摘要
血液相容性问题是影响心室辅助装置使用寿命及大量临床应用的重要因素之一。减少红细胞破坏和减少血液接触面积是目前可以提高血泵血液相容性的重要手段 ,为此我们 1997年到 1999年间研制了叶片为螺旋型且与血液接触面积小的螺旋血泵。血泵由泵体、螺旋叶轮、电机、医用硅橡胶密封圈和轴承等构成。叶轮的最大直径为 2 1 8mm ,最小直径是 9 8mm ,螺旋叶轮椎角 4 1 8度 ,泵体最大直径 30mm ,血泵为钛合金材料 ,体积 76ml,总重量 2 2 0g。体外试验结果显示 :1 螺旋血泵的输出是流量 4L min对应的平均压力为 10 0mmHg。 2 血泵的表面温度恒定在 39℃左右 ,密封性能良好。 3 螺旋血泵的溶血指数NIH为 0 0 85g 10 0L低于轴流血泵的NIH值 0 2 84g 10 0L ,且未在螺旋叶轮周围未发现任何微小血栓 ,证实螺旋血泵对血液的破坏明显低于轴流血泵。4 由于密封引起的产热和耗能尚待于改进。
The hemocompatibility is a very important feature of characteristics for a blood pump. The compatibility badly influences the life time and extent of clinical use of pumps. So far, the main method to increase the hemocompatibility of blood pump is to reduce the erythrocyte damage and the contact area. From 1997 to 1999, we developed a spiral blood pump. The spiral pump consists of a pump's housing, a spiral impeller, a brushless DC motor, a medical silicon rubber seal, and bearings. The maximum diameter of the impeller is 21\^8mm and minimum is 9\^8mm, the cone angle of the impeller threads is 41\^8 degrees, and the housing has a maximum diameter of 30mm. The blood pump was made of Titanium alloy, the volume was 76ml and its total weight was 220g. For vitro experiment,results were: 1\^The output flow rate was 4\^0L/min at 100mmHg average pressure when pump rotated at 10000rpm. 2\^The temperature of the pump's surface was fixed at about 39℃,and the performance of the seal was very good. 3\^The NIH result of the spiral pump was 0\^085±0\^021g/100L, which is lower than that of axial blood pump, representing 0\^284±0\^090g/100L. And there was not any small thrombus around the spiral impeller, which proved that the blood damage caused by the spiral pump was significantly lower than that of the axial blood pump. 4\^Nevertheless, we will improve the sealing structure so that the spiral pump will produce a lower amount of heat and consume less energy.
出处
《北京生物医学工程》
2003年第2期136-139,共4页
Beijing Biomedical Engineering
基金
国家"九五"重点攻关项目资助 ( 96-90 6-0 2 -14 )
