摘要
目的 :对 168例住院胰腺癌患者血清检测 ,评价它们在胰腺癌诊断中的作用。方法 :患者在治疗前进行检测CA199、AFP、CEA、CA5 0、CA12 5、AKP、LDH、γ GT ,超过正常标准者为阳性。结果 :65名患者中CA199阳性率 75 4 % ,119名患者中AFP阳性率 3 36% ,113名患者中CEA阳性率 38 9% ,117名患者中AKP阳性率 5 6 4 % ,113名患者中LDH阳性率 35 4 % ,119名患者中γ GT阳性率 5 8 8% ,4 2名患者CA5 0和 6名患者CA12 5的阳性率分别为 5 7 1%和 5 0 0 %。结论 :CA199可作为有价值的胰腺癌诊断指标 ,CA5 0 ,CA12 5 ,γ GT ,AKP可作为辅助参考指标 ,AFP ,LDH在胰腺癌临床诊断中价值不高 。
Objective To study the serum of 168 pancreatic cancer cases who were in-patient,and assess the serum assay's diagnostic value in pancreatic cancer.Methods The patients were detected carbohydrate antigen 199(CA199),alpha-fetoprotein(AFP),carcinoembryonic antigen(CEA),carbohydrate antigen50(CA50),carbohydrate antigen125(CA125),alkalin phosphatase(AKP),lactic dehydrogenase(LDH), r-glutamyl-transpeptidase(γ-GT) before treatment.The data which over than the normal standard means positive detection.Results The CA199 positive rate was 75.4% in 65 cases,the AFP positive rate was 3.36% in 119 cases,the CEA positive rate was 38.9% in 113 cases,the AKP positive rate was 56.4% in 117 cases,the LDH positive rate was 35.4% in 113 cases,theγ-GT positive rate was 58.8%,the CA50 and CA125 positive rate were 57.1% and 50.0% in 42 and 6 cases,respectively.Conclusions All of these serum detection show that CA199 determination has a good sensitivity and was the best index in the diagnosis of pancreatic cancer.It was superior to that of the other serum tumor markers currently available.The CA50,CA125,AKP,γ-GT might be helpful for the diagnosis in pancreatic cancer as a assistant.AFP and LDH have no diagnostic value in pancreatic cancer clinically.CEA can't be a routine index in the diagnosis of pancreatic cancer.
出处
《肿瘤防治杂志》
2003年第4期386-387,共2页
China Journal of Cancer Prevention and Treatment
关键词
胰腺肿瘤
诊断
血清学检查
肿瘤标注
生物学
pancreatic neoplasms/diagnosis
serologic tests
tumor markers,biological
