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补骨汤防治肾虚性绝经后骨质疏松症的实验观察 被引量:8

Experimental Observation of BuGuTang to Prevent and Ttreat Postmenopausal osteoporosis
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摘要 目的 :观察补骨汤对于绝经后骨质疏松症的防治作用。方法 :去势雌性大鼠作为绝经后骨质疏松症的实验模型 ,并将其分为补骨汤治疗组、模型空白组、骨疏康对照组 ,并与正常对照组进行组间对照比较 ,采用骨密度 ,骨矿含量等指标进行观察。结果显示 :补骨汤治疗组大鼠的骨密度 ,骨矿含量明显高于模型空白组(P<0 .0 5 ) ,而与正常对照组 ,骨疏康对照组比较 ,无显著性差异 (P>0 .0 5 )。结论 :说明补骨汤对于肾虚性绝经后骨质疏松症有良好的防治作用。 Objective:To observe the effects of BuGuTang that prevents and treats kidney deficient postmenopausal osteoporosis.Methods:Ovariectomized female rats were used as experimental model of kidney deficient postmenopausal osteoporosis, which were classified by BuGuTang group, model group and GuShuKang group, and compared with normal group. The parameters such as bone mineral density (BMD), bone mineral content (BMC) were observed.Results:The value of BMD and BMC in BuGuTang group were significantly higher than model group (P<0.05), but there were not significant difference in comparison with normal group and GuShuKang group (P>0.05).Conclusion:the results illustrated that BuGuTang possessed Very good effect on preventing and treating kidney deficient postmenopausal osteoporosis.
作者 毛碧峰
机构地区 沈阳市骨科医院
出处 《中国中医骨伤科杂志》 CAS 2003年第3期10-14,共5页 Chinese Journal of Traditional Medical Traumatology & Orthopedics
基金 研究生论文
关键词 补骨汤 绝经后骨质疏松症 骨密度 骨矿含量 大鼠 防治 肾虚性 BuGuTang Postmenopausal steoporosis Bone mineral density Bone mineral content Ovariectomized rat
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  • 1T. J. Wronski, M. Cintron, A. L. Dohorty. et al. Estrogen treatment prevents osteopenia and depresses bone turnover in ovariectomized rats. Endoerinol 1988,123 : 681.
  • 2Dike N. Kalu,et al. Evaluation of the pathogenesis of skeletal changes in ovariectomized rats. Endocrinol 1984, 115:507.

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