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CKS1 siRNA对人舌癌Tca8113细胞中CKS1蛋白的抑制作用 被引量:1

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摘要 目的探讨CKS1 siRNA对人舌鳞状细胞癌Tca8113细胞中CKS1蛋白的干扰作用。方法设计特异性CKS1插入序列,转入Tca8113细胞,应用免疫组化、RT-PCR、Western印迹检测Tca8113细胞中CKS1蛋白的表达。结果 CKS1 siRNA成功导入并抑制了Tca8113细胞中CKS1蛋白的表达(P<0.05)。结论 CKS1 siRNA能抑制Tca8113细胞中CKS1蛋白的表达,应用CKS1 siRNA治疗舌癌具有可行性。
出处 《中国老年学杂志》 CAS CSCD 北大核心 2015年第3期743-745,共3页 Chinese Journal of Gerontology
基金 吉林省发展和改革委员会资助项目(JF2012C006-8)
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