摘要
对慢性阻塞性肺气肿(简称慢阻肺)患者20例(男13例,女7例;年龄53±7a)采用硝苯啶10-15mg,tid,po×2wk,后改为5mg,tid,维持用药,总有效率95％,副作用轻微。另设24例慢阻肺患者(男17例,女7例,年龄52±6a)采用氨茶碱0.1-0.2g,tid,po,×2wk,总有效率71％,其中4例因副作用而停药。2组疗效比较无显著差别。
Twenty patients (M 13, F 7; age 53 + 7 a) suffering from chronic obstructive emphysema were given nifedipine 10-15 mg, tid, for 2 wk, then maintained on 5 mg, tid. The total response rate was 95%, and adverse effects were mild. The other group of 24 patients (M 17, F 7; age 52 + 6 a) were given aminophylline 0.1-0.2 g, tid, for 2 wk. The total response rate was 71 %. Four patients of the latter group were withdrawn due to adverse effects. It is suggested that the therapeutic effect of the nifedipine is similar to that of aminophylline (P>0.05).
出处
《新药与临床》
CSCD
北大核心
1992年第4期205-206,共2页
关键词
硝苯啶
氨茶碱
肺气肿
药物疗法
nifedipine/therapeutic use
aminophylline/therapeutic use
pulmonary emphysema/drug therapy
