摘要
目的:观察滋肾清肝颗粒剂治疗高催乳素血症(Hyperprolactinemia,HPRL)的临床疗效,并探讨其作用机制。方法:随机将患者分为治疗组(滋肾清肝颗粒剂)和对照组(溴隐停),每组20例。观察血中激素水平包括催乳素(PRL)、黄体生成素(LH)、卵泡刺激素(FSH)、雌二醇(E2)、孕酮(P)、雄激素(T);症状的变化;基础体温。结果:滋肾清肝颗粒剂可以有效的降低患者血中PRL水平,与对照组比较无显著性差异(P>0.05),对于其他相关激素有良好的调节作用;症状改善方面明显优于对照组(P<0.05),基础体温改善二者无显著性差异。结论:滋肾清肝颗粒可有效的治疗HPRL。
objective:To observe the therapeutic effects of treating hyperprolactinemia(HPRL) with nurishing kidney and clearing liver granule(NKCLG) and to explore its mechanism.Methods:40 patients were divided into two groups equally and randomly,NKCLG group and the control group(bromocriptine).observe:Changes of serum prolactin level and the relevant hormones(PRL、LH、FSH、E2、P、T);the symptoms;basal body temperature.Result:NKCLG could reduce the serum prolactin level in patient.There were no obvious differences between the effects on the NKCLG group and those on the control group.It could also regulate the level of the relevent hormones;NKCLG could remarkly mitigate the discomfort of the patients comparing the control group.The changes of the basal body temperature between the groups were no signifficantly different.Conclusion:NKCLG could effectively treat HPRL.
出处
《甘肃中医》
2004年第3期34-35,共2页
Gansu Journal of Traditional Chinese Medicine
关键词
滋肾清肝颗粒剂
高催乳素血症
临床观察
nurishing kidney and clearing liver granule
hyperprolactinemia
bromocrip- tine