摘要
目的 描述 1996～ 2 0 0 0年期间我国围产儿唇腭裂畸形的流行病学特征。方法 采用以医院为基础的监测方法收集资料。调查为监测医院内住院分娩的孕 2 8周～产后 7d的围产儿。结果 中国人围产儿总唇裂发生率为 14 0 0 /万 ,其中唇裂为 5 0 3/万 ,唇裂合并腭裂为 8 97/万 ;城镇发生率为 13 2 8/万 ,乡村为 15 5 7/万 ;男性为 16 0 6 /万 ,女性为 11 4 0 /万。总唇裂产妇年龄组别发生率差异有显著性 ,在≥ 35岁年龄组最大。年度发生率无长期趋势。总唇裂畸形以单发形式多见 ,占87 2 5 %。围产期病死率为 19 0 4 % ,单发畸形为 12 6 9% ,多发畸形为 6 2 6 0 %。结论 我国总唇裂发生率无下降趋势 ,和其他国家同期水平比较 ,属于高发地区。
Objective To describe the epidemiological features of cleft lip with or without cleft palate (CL±P) in Chinese perinatals. Methods From 1996 through 2000, hospital-based cluster sampling method was adopted for collecting data. During that period all live or still births with 28 weeks of gestation or more delivered in monitoring hospitals were assessed within 7 days after birth. Results The birth prevalence rates of cleft lip (CL) and of cleft lip with cleft palate (CLP) were 5.03/10 000, 8.97/ 10 000 respectively, then the rate of CL±P was 14.0/10 000. The prevalence rates in urban and rural area, in male and female births were 13.28/10 000 and 15.57/10 000, 16.06/10 000 and 11.40/10 000 respectively. Significant difference was found among maternal-age-specific prevalence rates, and the highest one was observed in ≥35 maternal age group. 87.25% of CL±P was isolated forms. No secular trend was found during that period. The perinatal fatality rate of CL±P was 19.04%, and the rate in isolated forms was 12.69%, but the rate in syndromic CL±P was as high as 62.60%. Conclusions No decline trend in prevalence rate of CL±P was observed during 1996～2000. Compared with prevalence rates of CL±P in some foreign countries, it was higher in China during same period.
出处
《中华口腔医学杂志》
CAS
CSCD
北大核心
2003年第6期438-440,共3页
Chinese Journal of Stomatology
