摘要
目的 探讨新生儿重症监护室 (NICU)中新生儿血液酸碱失衡和阴离子间隙 (AG)的特点。方法 对NICU中 86例新生儿进行血气分析、血电解质测定及AG测定。应用单纯性酸碱失衡代偿预期公式判断混合性酸碱失衡。对AG和血气的关系进行t检验。结果 83例 ( 96 5 1% )存在酸碱紊乱 ,其中以代谢性酸中毒合并呼吸性酸中毒为最多见 ( 6 1 6 3% )。本组未见三重酸碱紊乱的病例。高AG4 9例 ( 5 6 98% ) ,为新生儿特点。AG与血气关系显示 ,高AG组与正常AG组的血液pH、氧分压 (PO2 )、氧饱和度 (SO2 )之间差异无显著性 (P >0 0 5 ) ,而与二氧化碳分压 (PCO2 )差异有显著性 (P <0 0 5 ) ,与剩余碱 (BE)、碳酸氢根 (HCO3 ) -差异有高度显著性 (P <0 0 1) 。结论 NICU中新生儿以代谢性酸中毒合并呼吸性酸中毒为最多见。危重新生儿存在高AG现象 。
Objective To explore the characteristics of blood acid base disturbance and serum anion gap (AG) of neonates in neonatal intensive care unit (NICU).Methods Blood gas,serum electrolyte and AG of 86 neonates in NICU were detected.Using simple form acid base disturbance calculation formula to judge mixed acid base disturbance.Relation between blood gas and AG was analysed by test.Results 83 cases (96.51%) had acid base disturbance,in which the metabolic acidosis with respiratory acidosis was most common (61.63%).There was no triple acid base disturbance in this group.49 cases had high AG (56.98%),which was characteristic of neonates.The AG blood gas relationship showed that between the high AG group and the normal AG group there existed no significant difference of blood pH,PO 2,SO 2 (P>0.05),but marked difference of PCO 2 existed between them (P<0.05),and even more marked difference of BE,HCO - 3 between them (P<0 01).Conclusion Metabolic acidosis with respiratory acidosis was most common in neonates in NICU.Critical neonates have high AG phenomenon.High AG acidosis should be comprehensively treated.
出处
《山西医药杂志》
CAS
2004年第4期298-300,共3页
Shanxi Medical Journal
关键词
重症监护
新生儿
血气
阴离子间隙
酸碱平衡失调
Acid base imbalance
Acicl base equilibrium
Infant,newborn
Neonatal intensive care unit
