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超声乳化术中不同粘弹剂(Viscoat和透明质酸钠)对角膜内皮细胞的影响 被引量:8

The abilities of Viscoat and sodium hyaluronate to protect the corneal endothelium during endocapsular phacoemulsification
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摘要 目的 比较两种粘弹性物质Viscoat和透明质酸钠在白内障超声乳化手术中对角膜内皮的影响。方法 老年性白内障 49人 68眼 ,其中透明质酸钠组 2 5人 3 4眼 ,Viscoat组 2 4人 3 4眼 ,两组患者无内眼病史、眼外伤及眼内手术史 ,无糖尿病等全身疾病史。采用超声乳化术摘出白内障同时植入折叠性人工晶体 ,术前术后用非接触型角膜内皮显微镜观察测量角膜内皮细胞密度。结果 二组一般情况包括年龄 ,晶体核硬度及超声能量与时间的乘积无显著性差异 (P >0 0 5 ) ;透明质酸钠组术前和术后的角膜内皮细胞丢失率为 15 % ,经统计学处理有统计学意义 (P <0 0 5 )。Viscoat组术前和术后的角膜内皮细胞丢失率为 9% ,经统计学处理没有显普性差异 (P >0 0 5 )。 Objective To compare the ability of Viscoat and sodium hyaluronate to protec the corneal endothelium during endocapsular phacoemulsification and foldable intraocular lens implantation.Methods In 68 eyes of 49 senile cataract patients undergoing endocapular phacoemulsification with foldable intraocular lens implantation,In 34 eyes of 25 patients with sodium hyaluronate,in 34 eyes of 24 patients with Viscoat.One ophthalmologist performed all surgery.The endothelial cell density were measured in one week pre operation and two week postoperation.Results There were no statistically significant differences between two groups in age,cataract density,or phacoemulsification time during operation( P >0 05).There was statistically significant differences to compare before an after surgery for endothelial cell density in the sodium hyaluronate group( P <0 05).There was no significant differences to compare before and after surgery for endothelial cell density,it lose 9% in the Viscoat group( P <0 05).Conclusions Viscoat and sodium hyaluronate comparable in their ability to protect the corneal endothelium during phacoemulsication,this study suggested the Viscoat better than sodium hyaluronate for protect corneal endothelial cell.
出处 《中国实用眼科杂志》 CSCD 北大核心 2004年第4期294-295,共2页 Chinese Journal of Practical Ophthalmology
关键词 超声乳化术 粘弹剂 角膜内皮细胞 白内障 超声乳化手术 Cataract phacoemulsification Sodium hyaluronate
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参考文献4

  • 1Thomas J, Lieseg ang. Viscoelastic substances in Ophthalmology.Survey of Ophthalmology, 1990, 34 (4): 268~292
  • 2Glasser DB, Osbom DC, et al. Endothelial protection and viscoelastic retention during phacoemulsification and intraocular lens implantation.Arch Ophthalmology, 1991, 109:1438~1440
  • 3Craig MT, Olson RJ, Mamalis N, Olson RJ. Air bubble endothelial damage phacoemulsification in human eye bank eyes: the protective effects of Healon and Viscoat. Journal cataract refract surgery,1990, 16:597~602
  • 4Mark L. Mcdermott, Linda D Hazlett, et al. Viscoelastic adherence to corneal endothelium following phacoemulsification. Journal cataract refract surgery, 1998, 24:678~683

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