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经颅磁刺激:生理、心理、脑成像及其临床应用 被引量:22

Transcranial Magnetic Stimulation (TMS): Physiology, Psychology, Brain Mapping and Clinical Applications
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摘要 非侵入性的经颅磁刺激 (TranscranialMagneticStimulation ,TMS)可以无痛地产生感应性电流来激活皮层 ,从而改变大脑内的生理过程。通过改变TMS的参数可以观测到不同的生理和心理效应。TMS对大脑的不同的调节方式体现在对感觉的调节、对认知功能和行为表现的促进或抑制上。TMS还可以与神经病学、精神病学和药理学研究相结合。无框架的TMS立体定位技术可以提高用于解剖定位的TMS以及用于指引脑外科手术的准确性。最后 。 Non-invasive Transcranial Magnetic Stimulation (TMS) can painlessly induce conductive current to excite cortex. This changes physiological processing in the brain. Varying the parameters of TMS, differential physiologic effects, psychological impacts can be examined. Modulation of sensory perception, suppression or facilitation of cognitive capacity and behavioral performance depicts differential modulatory operation in the brain. TMS could be applied in the research of neurological disease, psychiatric disorders, and pharmacological investigation. Stereotaxic and frameless TMS can improve the anatomy-guided TMS and use for navigation in brain surgery. Finally, the principles derived from acupuncture mechanisms can be integrated into the frequency modulation effects on the brain, shared by TMS.
出处 《生理科学进展》 CAS CSCD 北大核心 2004年第2期102-106,共5页 Progress in Physiological Sciences
基金 国家重点基础研究专项经费 (2 0 0 3CB5 15 4 0 0 )资助课题
关键词 经颅磁刺激 生理学 心理学 脑成像 脑外科手术 TMS TMS physics Physiology Psychology Mechanisms and therapy
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