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热疗在恶性肿瘤综合治疗中的作用 被引量：22

Hyperthermia combine with other therapies for carcer therapy
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摘要 肿瘤的发生与多种因素有关。目前 ,对恶性肿瘤强调有计划的综合治疗 ,而热疗是综合治疗的手段之一。研究表明 ,热疗可通过影响多个肿瘤发生的相关因素来达到杀伤肿瘤细胞和提高机体免疫功能的目的。 The mechanism of carcinoma occurrence is of multiform. One of the scheduled multi modality treatment is hyperthermia. Result of research indicates that hyperthermia can kills the tumor cells by affecting carcinogens, tumor suppressors and immunity. This review presents the current knowledge of hyperthermia on mechanism of therapeutic effects and the application in the treatment.
作者 鹿红 陈龙邦
机构地区 南京军区南京总医院南京大学医学院临床学院肿瘤科
出处 《医学研究生学报》 CAS 2004年第5期458-460,共3页 Journal of Medical Postgraduates
关键词 热疗 放疗 化疗 肿瘤 Hyperthermia Radiotherapy Chemotherapy Carcinoma
分类号 R730.59 [医药卫生—肿瘤]
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参考文献20

  • 1[1]Robins HI, Grosen E, Katschinski DM et al. Whole body hyperthermia induction of soluble tumor necrosis factor receptors: implications for rheumatoid disease [J]. J Rheumatol, 1999, 26(12):2513-2516.
  • 2[2]Katschinski DM, Benndorf R, Wiedemann GJ et al. Heat shock protein antibodies in sarcoma patients undergoing 41.8 C whole body hyperthermia[J]. J Immunother, 1999, 22(1):67-70.
  • 3[3]Morita M, Kuwano H, Araki K et al. Prognostic significance of lymphocyte infiltration following preoperative chemoradiotherapy and hyperthermia for esophageal cancer[J]. Int J Radiat Oncol Biol Phys, 2001, 49(5):1259-1266.
  • 4[4]Masunaga S, Ono K, Takahashi A et al. Usefulness of combined treatment with mild temperature hyperthermia and/or tirapazamine in the treatment of solid tumors: its independence of p53 status[J]. Cancer Sci, 2003, 94(1):125-133.
  • 5[5]Roca C, Primo L, Valdembri D et al. Hyperthermia inhibits angiogenesis by a plasminogen activator inhibitor 1-dependent mechanism[J]. Cancer Res, 2003, 63(7):1500-1507.
  • 6[6]Ressel A, Weiss C, Feyerabend T. Tumor oxygenation after radiotherapy, chemotherapy, and/or hyperthermia predicts tumor free survival[J]. Int J Radiat Oncol Biol Phys, 2001, 49(4):1119-1125.
  • 7[7]Van der Zee J. Heating the patient: a promising approach?[J] Ann Oncol, 2002, 13(8):1173-1784.
  • 8[8]Hehr T, Budach W, Lamprecht U et al.Experimental thermoradiotherapy in malignant hepatocellular carcinoma[J]. Int J Radiat Oncol Biol Phys, 2003, 55(5):1374-1380.
  • 9鹿红,李兵,熊晓斌,胡晓琳,高淑萍,张瑞忠.食管癌外照射结合低剂量率腔内照射加热疗的疗效分析[J].医学研究生学报,2002,15(4):340-342. 被引量：10
  • 10[10]Arends J.Effects of a combined thermochemotherapy on markers of apoptosis, differentiation and adhesion in the human mammary carcinoma MX-1.A light microscopic and immunohistochemical study[J]. Anat Anz, 2000,182(4):339-347.

二级参考文献20

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共引文献17

同被引文献167

引证文献22

二级引证文献110

医学研究生学报
2004年 第5期

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