Myocardial infarction-induced heart failure (HF) is the leading cause of mortality and disability worldwide [1]. Studies have established that HF is characterized by impaired mitochondrial energy production [2]. Hence...Myocardial infarction-induced heart failure (HF) is the leading cause of mortality and disability worldwide [1]. Studies have established that HF is characterized by impaired mitochondrial energy production [2]. Hence, pharmacological targeting of energy production pathways has emerged as a promising strategy against HF [3]. Retinoid X receptor a (RXRa) is a ligand-activated transcription factor.展开更多
基金supported by the National Natural Science Foundation of China (82174215, 82230126, 82174364, 82374420,82305025 and 82222075)the Fundamental Research Funds for the Central Universities (Distinguished project)+1 种基金Science and Technology Department of Beijing University of Chinese Medicine(BZY-JMZY-2022-001)“High level Key Discipline of National Administration of Traditional Chinese Medicine-Traditional Chinese Constitutional Medicine (zyyzdxk-2023251)”。
文摘Myocardial infarction-induced heart failure (HF) is the leading cause of mortality and disability worldwide [1]. Studies have established that HF is characterized by impaired mitochondrial energy production [2]. Hence, pharmacological targeting of energy production pathways has emerged as a promising strategy against HF [3]. Retinoid X receptor a (RXRa) is a ligand-activated transcription factor.
