The formation of multiple oxygen intermediates supporting efficient oxygen evolution reaction(OER)are affinitive with hydroxyl adsorption.However,ability of the catalyst to capture hydroxyl and maintain the continuous...The formation of multiple oxygen intermediates supporting efficient oxygen evolution reaction(OER)are affinitive with hydroxyl adsorption.However,ability of the catalyst to capture hydroxyl and maintain the continuous supply at active sits remains a tremendous challenge.Herein,an affordable Ni2P/FeP2 heterostructure is presented to form the internal polarization field(IPF),arising hydroxyl spillover(HOSo)during OER.Facilitated by IPF,the oriented HOSo from FeP2 to Ni2P can activate the Ni site with a new hydroxyl transmission channel and build the optimized reaction path of oxygen intermediates for lower adsorption energy,boosting the OER activity(242 mV vs.RHE at 100 mA cm-2)for least 100 h.More interestingly,for the anion exchange membrane water electrolyzer(AEMWE)with low concentration electrolyte,the advantage of HOSo effect is significantly amplified,delivering 1 A cm^(-2)at a low cell voltage of 1.88 V with excellent stability for over 50 h.展开更多
Summary What is already known about this topic?Silica dust and coal dust are the main occupational hazards in coal-fired thermal power plants,which mainly exist in coal transportation workplaces,combustion milling wor...Summary What is already known about this topic?Silica dust and coal dust are the main occupational hazards in coal-fired thermal power plants,which mainly exist in coal transportation workplaces,combustion milling workplaces,and ash removal workplaces.What is added by this report?The overall environmental and personal dust exposure levels decrease with an increase in the capacity of coalfired thermal power plants.展开更多
Iron plays a crucial role in improving the oxygen evolution reaction(OER)activity of hydroxide materials.Increasing the number of iron active sites at the solid–liquid interface is beneficial to enhancing the OER per...Iron plays a crucial role in improving the oxygen evolution reaction(OER)activity of hydroxide materials.Increasing the number of iron active sites at the solid–liquid interface is beneficial to enhancing the OER performance of catalysts but still challenging.Here,by systematic exploring the activity trends of M(OH)_(x)and Cu-M(OH)_(x)(M=Mn,Cu,Ni,Fe,and Co),we discover that the Cu doping can promote the deposition of Fe active sites on metal hydroxide and Cu-Co(OH)2 shows the most favorable iron adsorption capacity.When loaded on a conductive substrate(cobalt foam(CF),the M-Cu-Co(OH)2/CF(Co(OH)_(2))prepared by molten salt method)exhibits an attractive low overpotential of 337 mV at 1,000 mA·cm^(−2).Using in anion exchange membrane(AEM)water electrolyzer,the single cell with M-Cu-Co(OH)_(2)/CF as anode catalyst performs a stable cell voltage of 2.02 V to reach 1,000 mA·cm^(−2)over 24 h,indicating a great application potential for actual electrolytic water.Therefore,the promoted adsorption of copper on iron provides a new perspective for further enhancing the OER activity of other metal hydroxides.展开更多
Debates persist regarding the efficacy and safety of azvudine,particularly its real-world outcomes.This study involved patients aged 60 years who were admitted to 25 hospitals in China's Mainland with confirmed SA...Debates persist regarding the efficacy and safety of azvudine,particularly its real-world outcomes.This study involved patients aged 60 years who were admitted to 25 hospitals in China's Mainland with confirmed SARS-CoV-2 infection between December 1,2022,and February 28,2023.Efficacy outcomes were all-cause mortality during hospitalization,the proportion of patients discharged with recovery,time to nucleic acid-negative conversion(TNANC),time to symptom improvement(TSI),and time of hospital stay(THS).Safety was also assessed.Among the 5884 participants identified,1999 received azvudine,and 1999 matched controls were included after exclusion and propensity score matching.Azvudine recipients exhibited lower all-cause mortality compared with controls in the overall population(13.3%vs.17.1%,RR,0.78;95%CI,0.67e0.90;P Z 0.001)and in the severe subgroup(25.7%vs.33.7%;RR,0.76;95%CI,0.66e0.88;P<0.001).A higher proportion of patients discharged with recovery,and a shorter TNANC were associated with azvudine recipients,especially in the severe subgroup.The incidence of adverse events in azvudine recipients was comparable to that in the control group(2.3%vs.1.7%,P Z 0.170).In conclusion,azvudine showed efficacy and safety in older patients hospitalized with COVID-19 during the SARS-CoV-2 omicron wave in China.展开更多
基金This work is financially supported by National Natural Science Foundation of China(52174283 and 52274308)Innovation Fund Project for Graduate Student of China University of Petroleum(East China)(22CX04023A)the Fundamental Research Funds for the Central Universities。
文摘The formation of multiple oxygen intermediates supporting efficient oxygen evolution reaction(OER)are affinitive with hydroxyl adsorption.However,ability of the catalyst to capture hydroxyl and maintain the continuous supply at active sits remains a tremendous challenge.Herein,an affordable Ni2P/FeP2 heterostructure is presented to form the internal polarization field(IPF),arising hydroxyl spillover(HOSo)during OER.Facilitated by IPF,the oriented HOSo from FeP2 to Ni2P can activate the Ni site with a new hydroxyl transmission channel and build the optimized reaction path of oxygen intermediates for lower adsorption energy,boosting the OER activity(242 mV vs.RHE at 100 mA cm-2)for least 100 h.More interestingly,for the anion exchange membrane water electrolyzer(AEMWE)with low concentration electrolyte,the advantage of HOSo effect is significantly amplified,delivering 1 A cm^(-2)at a low cell voltage of 1.88 V with excellent stability for over 50 h.
基金The National Natural Science Foundation of China(81472956,30972449)the Occupational Health Risk Assessment and National Occupational Health Standard Setting Project(131031109000150003)of the National Institute of Occupational Health and Poison Control,Chinese Center for Disease Control and Prevention.
文摘Summary What is already known about this topic?Silica dust and coal dust are the main occupational hazards in coal-fired thermal power plants,which mainly exist in coal transportation workplaces,combustion milling workplaces,and ash removal workplaces.What is added by this report?The overall environmental and personal dust exposure levels decrease with an increase in the capacity of coalfired thermal power plants.
基金supported by the National Natural Science Foundation of China(No.52174283)Innovation Fund Project for Graduate Student of China University of Petroleum(East China)(No.22CX04026A)the Fundamental Research Funds for the Central Universities.
文摘Iron plays a crucial role in improving the oxygen evolution reaction(OER)activity of hydroxide materials.Increasing the number of iron active sites at the solid–liquid interface is beneficial to enhancing the OER performance of catalysts but still challenging.Here,by systematic exploring the activity trends of M(OH)_(x)and Cu-M(OH)_(x)(M=Mn,Cu,Ni,Fe,and Co),we discover that the Cu doping can promote the deposition of Fe active sites on metal hydroxide and Cu-Co(OH)2 shows the most favorable iron adsorption capacity.When loaded on a conductive substrate(cobalt foam(CF),the M-Cu-Co(OH)2/CF(Co(OH)_(2))prepared by molten salt method)exhibits an attractive low overpotential of 337 mV at 1,000 mA·cm^(−2).Using in anion exchange membrane(AEM)water electrolyzer,the single cell with M-Cu-Co(OH)_(2)/CF as anode catalyst performs a stable cell voltage of 2.02 V to reach 1,000 mA·cm^(−2)over 24 h,indicating a great application potential for actual electrolytic water.Therefore,the promoted adsorption of copper on iron provides a new perspective for further enhancing the OER activity of other metal hydroxides.
基金funded by National High Level Hospital Clinical Research Funding(BJ-2022-173,China)National Health Commission Clinical Research Projects for Innovative Drugs(WKZX2023CX210007,China).
文摘Debates persist regarding the efficacy and safety of azvudine,particularly its real-world outcomes.This study involved patients aged 60 years who were admitted to 25 hospitals in China's Mainland with confirmed SARS-CoV-2 infection between December 1,2022,and February 28,2023.Efficacy outcomes were all-cause mortality during hospitalization,the proportion of patients discharged with recovery,time to nucleic acid-negative conversion(TNANC),time to symptom improvement(TSI),and time of hospital stay(THS).Safety was also assessed.Among the 5884 participants identified,1999 received azvudine,and 1999 matched controls were included after exclusion and propensity score matching.Azvudine recipients exhibited lower all-cause mortality compared with controls in the overall population(13.3%vs.17.1%,RR,0.78;95%CI,0.67e0.90;P Z 0.001)and in the severe subgroup(25.7%vs.33.7%;RR,0.76;95%CI,0.66e0.88;P<0.001).A higher proportion of patients discharged with recovery,and a shorter TNANC were associated with azvudine recipients,especially in the severe subgroup.The incidence of adverse events in azvudine recipients was comparable to that in the control group(2.3%vs.1.7%,P Z 0.170).In conclusion,azvudine showed efficacy and safety in older patients hospitalized with COVID-19 during the SARS-CoV-2 omicron wave in China.
