Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biot...Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.展开更多
Purpose:The disseminating of academic knowledge to nonacademic audiences partly relies on the transition of subsequent citing papers.This study aims to investigate direct and indirect impact on technology and policy o...Purpose:The disseminating of academic knowledge to nonacademic audiences partly relies on the transition of subsequent citing papers.This study aims to investigate direct and indirect impact on technology and policy originating from transformative research based on ego citation network.Design/methodology/approach:Key Nobel Prize-winning publications(NPs)in fields of gene engineering and astrophysics are regarded as a proxy for transformative research.In this contribution,we introduce a network-structural indicator of citing patents to measure technological impact of a target article and use policy citations as a preliminary tool for policy impact.Findings:The results show that the impact on technology and policy of NPs are higher than that of their subsequent citation generations in gene engineering but not in astrophysics.Research limitations:The selection of Nobel Prizes is not balanced and the database used in this study,Dimensions,suffers from incompleteness and inaccuracy of citation links.Practical implications:Our findings provide useful clues to better understand the characteristics of transformative research in technological and policy impact.Originality/value:This study proposes a new framework to explore the direct and indirect impact on technology and policy originating from transformative research.展开更多
The design and fabrication method of magnetic field coils with high uniformity is essential for atomic magnetometers.In this paper,a novel design strategy for cylindrical uniform coils is first proposed,which combines...The design and fabrication method of magnetic field coils with high uniformity is essential for atomic magnetometers.In this paper,a novel design strategy for cylindrical uniform coils is first proposed,which combines the target-field method(TFM)with an optimized slime mold algorithm(SMA)to determine optimal structure parameters.Then,the realization method for the designed cylindrical coil by using the flexible printed circuit(FPC)technology is presented.Compared with traditional fabrication methods,this method has advantages in excellent flexibility and bending property,making the coils easier to be arranged in limited space.Moreover,the manufacturing process of the FPC technology via a specific cylindrical uniform magnetic field coil is discussed in detail,and the successfully realized coil is well tested in a verification system.By comparing the uniformity performance of the experimental coil with the simulation one,the effectiveness of the FPC technology in producing cylindrical coils has been well validated.展开更多
The rapid development of communication technology and computer networks has brought a lot of convenience to production and life,but it also increases the security problem.Information security has become one of the sev...The rapid development of communication technology and computer networks has brought a lot of convenience to production and life,but it also increases the security problem.Information security has become one of the severe challenges faced by people in the digital age.Currently,the security problems facing the field of communication technology and computer networks in China mainly include the evolution of offensive technology,the risk of large-scale data transmission,the potential vulnerabilities introduced by emerging technology,and the dilemma of user identity verification.This paper analyzes the frontier challenges of communication technology and computer network security,and puts forward corresponding solutions,hoping to provide ideas for coping with the security challenges of communication technology and computer networks.展开更多
In recent years,perovskite solar cells(PSCs)have garnered significant attention as a potential mainstream technology in the future photovol-taic(PV)market.This is primarily attributed to their salient advantages inclu...In recent years,perovskite solar cells(PSCs)have garnered significant attention as a potential mainstream technology in the future photovol-taic(PV)market.This is primarily attributed to their salient advantages including high efficiency,low cost,and ease of preparation.Nota-bly,the power conversion efficiency(PCE)of PSCs has experienced a remarkable increase from 3.8%in 2009 to over 26%at present.Conse-quently,the adoption of roll-to-roll(R2R)technology for PSCs is considered a crucial step towards their successful commercialization.This arti-de reviews the diverse substrates,scalable deposition techniques(such as solution-based knife-coating and spraying technology),and optimiza.tion procedures employed in recent years to enhance device performance within the R2R process.Additionally,novel perspectives are presented to enrich the existing knowledge in this field.展开更多
Objective The aim of this study was to explore the action mechanism of Sanhua decoction in treating ischemic stroke through network pharmacology and molecular docking technology.Methods Active components and related t...Objective The aim of this study was to explore the action mechanism of Sanhua decoction in treating ischemic stroke through network pharmacology and molecular docking technology.Methods Active components and related targets of Sanhua decoction were obtained from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform.A“drug-active component-target”network was constructed,and core components were selected throughtopological analysis.Disease targets related to ischemic stroke were screened based on the Online Mendelian Inheritance in Man(OMIM),Therapeutic Target Database(TTD),GeneCards,DrugBank,and PharmGKB databases.The intersection of active component–related targets and ischemic stroke disease targets was identified to obtain potential targets of Sanhua decoction for treating ischemic stroke,represented using a Venn diagram.The STRING database was used to construct a protein–protein interaction(PPI)network of potential targets and filter for core targets.Gene Ontology(GO)functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis of core targets were performed using the DAVID database and Metascape platform.Molecular docking verification of core targets and core components was conducted using AutoDock.Results A total of 52 active components and 142 related targets were screened from Sanhua decoction,with core active components including luteolin,nobiletin,β-sitosterol,eucalyptol,and aloe-emodin.There were 2,991 ischemic stroke–related targets,with 98 potential targets identified in the intersection with active component–related targets.An analysis of the PPI network analysis revealed 23 core targets,including serine/threonine-protein kinase 1(AKT1),tumor protein p53(TP53),and mitogen-activated protein kinase 3(MAPK3).Enrichment analysis obtained 35 GO results and 41 signaling pathways.Molecular docking results indicated good binding between core components and core targets.Conclusion Multiple components in the classic formula Sanhua decoction,such as luteolin and nobiletin,may play a role in treating ischemic stroke by regulating core targets like AKT1,TP53,and MAPK3,and participating in multiple signaling pathways.展开更多
In recent years,artificial intelligence technology has developed rapidly around the world is widely used in various fields,and plays an important role.The integration of industrial Internet security with new technolog...In recent years,artificial intelligence technology has developed rapidly around the world is widely used in various fields,and plays an important role.The integration of industrial Internet security with new technologies such as big models and generative artificial intelligence has become a hot research issue.In this regard,this paper briefly analyzes the industrial Internet security technology and application from the perspective of generative artificial intelligence,hoping to provide some valuable reference and reference for readers.展开更多
With the continuous development of computer network technology, its applications in daily life and work have become increasingly widespread, greatly improving efficiency. However, certain security risks remain. To ens...With the continuous development of computer network technology, its applications in daily life and work have become increasingly widespread, greatly improving efficiency. However, certain security risks remain. To ensure the security of computer networks and databases, it is essential to enhance the security of both through optimization of technology. This includes improving management practices, optimizing data processing methods, and establishing comprehensive laws and regulations. This paper analyzes the current security risks in computer networks and databases and proposes corresponding solutions, offering reference points for relevant personnel.展开更多
Special Purpose Rice (SPR) is a technology that consists of different rice varieties that were developed by Central Luzon State University. The unique varietal characteristics of SPR are pigmented, glutinous, good-yie...Special Purpose Rice (SPR) is a technology that consists of different rice varieties that were developed by Central Luzon State University. The unique varietal characteristics of SPR are pigmented, glutinous, good-yielding varieties planted in lowland areas. This study was conducted to increase farmers’ income through employing different promotion and extension activities and enterprise development. Data were analyzed using descriptive statistics. Cost and return and benefit-cost analysis were used to determine the financial benefits of using the SPR in different production systems. Results revealed that incorporating the following parameters is critical in the sustainable adoption of the SPR. Amongst them are: ensuring that recommended production technologies are strictly followed by the farmers, ensuring the quality of seeds for planting, the presence of a market for the produce, engaging the farmers in value-adding activities like processing, capability development in entrepreneurship, and adopting clustering approach of the farmers to address economies of scale in marketing and processing. The use of SPR produced an average yield of 6.11 MT/ha and 5.04 MT/ha during the dry and wet seasons from 2021-2023, respectively, higher than the usual varieties of inbred rice. The net benefit from producing a CLS-2 variety of SPR is higher than regular rice, having an average difference of Php 22,355.53 per hectare from 2021-2023.展开更多
Cracks are important migration channels and storage spaces for oil and gas, and the peripheral cracks in the Ordos Basin have developed extensively after multiple tectonic movements. Using unmanned aerial vehicle obli...Cracks are important migration channels and storage spaces for oil and gas, and the peripheral cracks in the Ordos Basin have developed extensively after multiple tectonic movements. Using unmanned aerial vehicle oblique photogrammetry technology to obtain field outcrop image data and establish a three-dimensional model for observation, the NEE and NNW fractures are the most developed in the Yanchang Formation of the study area, while the NW and NNE fractures are slightly developed, all of which are high angle vertical fractures and belong to regional structural fractures. The NNW oriented cracks are restricted by the NEE oriented cracks and developed in the late stage. Combined with the analysis of regional geological background, fracture intersection relationship and tectonic stress field, it is considered that there are two stages of fractures in Dongjiahe, namely, the late Indosinian and Yanshanian.展开更多
The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relations...The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relationships between knowledge modeling, institutional memory, leadership styles, technology, and administrative efficiency at the University of Cape Coast (UCC). The study sought to identify the challenges and opportunities in integrating digital tools into administrative processes and to provide actionable recommendations for improvement. A mixed-methods research design was employed, combining quantitative analysis using Partial Least Squares Structural Equation Modeling (PLS-SEM) with qualitative thematic analysis of interviews. The findings revealed key challenges, including resistance to change, fragmented knowledge repositories, and inadequate funding, alongside opportunities such as centralized knowledge systems, cost-effective open-source tools, and capacity-building initiatives. The study highlights the importance of strategic leadership, robust policies, and investments in digital infrastructure to enhance administrative practices. Policy implications include the need for clear digital transformation guidelines and leadership training to foster innovation and collaboration. Recommendations include investing in scalable digital tools, implementing comprehensive capacity-building programs, and promoting stakeholder engagement to drive successful digital integration. These insights provide a roadmap for UCC and similar institutions seeking to optimize administrative efficiency through digital transformation.展开更多
The world today is undergoing disruptive,transformative shifts driven by a new wave of technological revolutions and industrial changes.In this context,a central question for China’s innovation-driven development str...The world today is undergoing disruptive,transformative shifts driven by a new wave of technological revolutions and industrial changes.In this context,a central question for China’s innovation-driven development strategy is how to effectively identify and measure high-quality technological innovations.Drawing on the stylized facts and scenario narrative of China’s technological landscape,this paper proposes a framework and measurement system for evaluating high-quality technological innovations.While China’s top-level design for technological innovation is guided by policy documents,the increasing number of enterprises applying for“high-tech enterprise”status has coincided with a decline in the quality of patent filings.In response,this paper first underscores the challenges and necessity of measuring the quality of technological innovations.Second,we introduce the high-quality technological innovation indicators and employ them to assess the quality of tech innovations at the firm level,utilizing an approach that combines analogical narrative,gene coding,text analysis,semantic logic,and a database of granted invention patents in China.Third,we examine the systematic and individual biases inherent in citation counts,a commonly used indicator,under specific contexts,and employ a granular instrumental variable approach to validate the effectiveness of the indicators.Finally,we develop a“family tree”of the indicators and explore their application scenarios through a combination of established and extended indicators.Our findings provide a theoretical foundation for evaluating China’s technological innovation quality,inform policy incentives,and offer insights for academia to apply high-quality technological innovation indicators in different contexts.展开更多
High-power laser technology is widely used in manufacturing processing,medical diagnosis,and treatment,and is one of the important fields of strategic high-tech competition in China at the moment.In the context of ind...High-power laser technology is widely used in manufacturing processing,medical diagnosis,and treatment,and is one of the important fields of strategic high-tech competition in China at the moment.In the context of industrial upgrading,high-power laser technology plays an important role in leading the development of the manufacturing industry and industrial intelligence.Based on this,this paper carries out research on high-power laser technology and industry,summarizes the basic principle and classification of high-power laser technology,analyzes the current status of high-power laser technology industry,points out the opportunities and challenges faced by the industry development,puts forward suggestions to promote the development of high-power laser technology industry,and to provide an effective reference for the application and development of high-power laser technology.展开更多
This paper systematically elucidates the application of plasma technology in cancer treatment,including its principles,case studies,comparative advantages over traditional methods,challenges,and countermeasures.Plasma...This paper systematically elucidates the application of plasma technology in cancer treatment,including its principles,case studies,comparative advantages over traditional methods,challenges,and countermeasures.Plasma technology targets and eliminates cancer cells with precision through physical,chemical,and immune-regulatory mechanisms,offering high accuracy and low side effects.International applications include plasma scalpels in the United States,combined chemotherapy and low-temperature plasma therapy in Russia,and plasma-targeted capture technology in China.However,plasma technology faces technical hurdles and clinical application barriers,requiring interdisciplinary collaboration and industry-academia-research cooperation to advance its development.展开更多
With the advent of the information age,people’s production and life are more closely connected with the Internet.Internet technology not only improves the production efficiency,but also provides great convenience for...With the advent of the information age,people’s production and life are more closely connected with the Internet.Internet technology not only improves the production efficiency,but also provides great convenience for people’s life.At present,people’s requirements for computer information technology are gradually increasing.When we look directly at the information transmission and storage capacity,computer information technology cannot meet the market demand.Due to rapid development,the integration of artificial intelligence(AI)can enable the development of computer information technology.In this paper,computer information technology and artificial intelligence integration act as a starting point,and the integration of the development of the two is analyzed for reference.展开更多
To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-minin...To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-mining technology system with non-pillar in mines(ETSNM)in recent years.The petal warning criterion for the stability of the surrounding rock of the roadway at the end-mining stage was obtained by studying the inverse problem of the petal theorem.A conformal mathematical model of the end-mining stage was established using the conformal mapping method,and the limit theorem of the peak point of mine pressure(LTPPMP)in the end-mining stage was demonstrated.Based on the cross-fusion of the above basic mathematical theory and the LTPPMP,a new ETSNM model was proposed,which includes no coal pillar,no dedicated retracement roadways,and fast retracement equipment(NNF).The mathematical principles of engineering technology for height control,speed limit,and roof cutting in the end-mining stage with non-pillar were revealed.The scientific and application values of the ETSNM were confirmed through engineering applications.Based on this,a new non-pillar control technology for dynamic disasters in the end-mining stage was proposed.The above research will play an active role in promoting the engineering application of ETSNM driven by mathematical theory.展开更多
The Advanced French course is a core subject for the major of French,and ideological and political education is an important component of its teaching.By restructuring the teaching content according to the educational...The Advanced French course is a core subject for the major of French,and ideological and political education is an important component of its teaching.By restructuring the teaching content according to the educational modules of ideological and political education,we can provide a more comprehensive and systematic educational experience.Empowered by information technology,this approach broadens the dimensions of ideological and political education in the Advanced French course.Meanwhile,the learning outcomes from the“first classroom”can be transformed into the results of the“second classroom”through social platforms such as WeChat public accounts,micro-video competitions,and innovation projects,achieving the effect of spreading Chinese culture and telling Chinese stories.By using diverse evaluation criteria,we continuously improve teaching and learning activities and innovate the teaching model of ideological and political education.展开更多
As one of the commonly used technologies in modern civil engineering,the construction technology is becoming more and more widely used with the continuous growth of building height.In the construction process of highr...As one of the commonly used technologies in modern civil engineering,the construction technology is becoming more and more widely used with the continuous growth of building height.In the construction process of highrise buildings,the deep foundation pit support provides the necessary stability for the foundation structure of the building project,and more effectively guarantees the quality of the project.Through the reasonable supporting structure,the deep foundation pit technology can effectively prevent the risk of soil collapse,foundation pit deformation and other risks,and improve the safety factor of the whole construction project.Especially in the high-rise buildings,the deep foundation pit support technology can consolidate the foundation for the long-term stability of the project,and significantly prolong the service life of the building.The continuous development of deep foundation pit construction technology is the inevitable demand of high-rise building construction,and also provides a powerful help for the development of civil engineering industry.Based on this,this paper focuses on the application of deep foundation pit construction technology in civil engineering construction.展开更多
When the expressway crosses the goafs inevitably,the design is generally to build the road on coal pillars as much as possible.However,the existing coal pillars are often unable to meet relevant requirements of highwa...When the expressway crosses the goafs inevitably,the design is generally to build the road on coal pillars as much as possible.However,the existing coal pillars are often unable to meet relevant requirements of highway construction.Combining three-dimensional physical model tests,numerical simulations and fi eld monitoring,with the Urumqi East Second Ring Road passing through acute inclined goafs as a background,the deformation and failure mechanism of the overlying rock and coal pillars in acute inclined goafs under expressway load were studied.And in accordance with construction requirements of subgrade,comprehensive consideration of the deformation and instability mechanism of acute inclined goafs,the treatment measures and suggestions for this type of geological disasters were put forward.The research results confi rmed the rationality of coal pillars in acute inclined goafs under the expressway through grouting.According to the ratio of diff erent overlying rock thickness to coal pillar height,the change trend and value of the required grouting range were summarized,which can provide reference for similar projects.展开更多
基金supported by grants from the National Key R&D Program of China,No.2017YFC0909200(to DC)the National Natural Science Foundation of China,No.62075225(to HZ)+1 种基金Zhejiang Provincial Medical Health Science and Technology Project,No.2023XY053(to ZP)Zhejiang Provincial Traditional Chinese Medical Science and Technology Project,No.2023ZL703(to ZP).
文摘Terahertz biotechnology has been increasingly applied in various biomedical fields and has especially shown great potential for application in brain sciences.In this article,we review the development of terahertz biotechnology and its applications in the field of neuropsychiatry.Available evidence indicates promising prospects for the use of terahertz spectroscopy and terahertz imaging techniques in the diagnosis of amyloid disease,cerebrovascular disease,glioma,psychiatric disease,traumatic brain injury,and myelin deficit.In vitro and animal experiments have also demonstrated the potential therapeutic value of terahertz technology in some neuropsychiatric diseases.Although the precise underlying mechanism of the interactions between terahertz electromagnetic waves and the biosystem is not yet fully understood,the research progress in this field shows great potential for biomedical noninvasive diagnostic and therapeutic applications.However,the biosafety of terahertz radiation requires further exploration regarding its two-sided efficacy in practical applications.This review demonstrates that terahertz biotechnology has the potential to be a promising method in the field of neuropsychiatry based on its unique advantages.
基金supported by the National Natural Science Foundation of China(Grant No.71974167).
文摘Purpose:The disseminating of academic knowledge to nonacademic audiences partly relies on the transition of subsequent citing papers.This study aims to investigate direct and indirect impact on technology and policy originating from transformative research based on ego citation network.Design/methodology/approach:Key Nobel Prize-winning publications(NPs)in fields of gene engineering and astrophysics are regarded as a proxy for transformative research.In this contribution,we introduce a network-structural indicator of citing patents to measure technological impact of a target article and use policy citations as a preliminary tool for policy impact.Findings:The results show that the impact on technology and policy of NPs are higher than that of their subsequent citation generations in gene engineering but not in astrophysics.Research limitations:The selection of Nobel Prizes is not balanced and the database used in this study,Dimensions,suffers from incompleteness and inaccuracy of citation links.Practical implications:Our findings provide useful clues to better understand the characteristics of transformative research in technological and policy impact.Originality/value:This study proposes a new framework to explore the direct and indirect impact on technology and policy originating from transformative research.
基金Project supported by the National Natural Science Foundation of China(Grant No.62101004)the Opening Research Fund of Anhui Engineering Research Center of Vehicle Display Integrated Systems(Grant No.VDIS2023C05)+1 种基金the Opening Project of Key Laboratory of Electric Drive and Control of Anhui Province,China(Grant No.DQKJ202309)the Excellent Scientific Research and Innovation Teams of Anhui Province,China(Grant No.2022AH010059)。
文摘The design and fabrication method of magnetic field coils with high uniformity is essential for atomic magnetometers.In this paper,a novel design strategy for cylindrical uniform coils is first proposed,which combines the target-field method(TFM)with an optimized slime mold algorithm(SMA)to determine optimal structure parameters.Then,the realization method for the designed cylindrical coil by using the flexible printed circuit(FPC)technology is presented.Compared with traditional fabrication methods,this method has advantages in excellent flexibility and bending property,making the coils easier to be arranged in limited space.Moreover,the manufacturing process of the FPC technology via a specific cylindrical uniform magnetic field coil is discussed in detail,and the successfully realized coil is well tested in a verification system.By comparing the uniformity performance of the experimental coil with the simulation one,the effectiveness of the FPC technology in producing cylindrical coils has been well validated.
文摘The rapid development of communication technology and computer networks has brought a lot of convenience to production and life,but it also increases the security problem.Information security has become one of the severe challenges faced by people in the digital age.Currently,the security problems facing the field of communication technology and computer networks in China mainly include the evolution of offensive technology,the risk of large-scale data transmission,the potential vulnerabilities introduced by emerging technology,and the dilemma of user identity verification.This paper analyzes the frontier challenges of communication technology and computer network security,and puts forward corresponding solutions,hoping to provide ideas for coping with the security challenges of communication technology and computer networks.
文摘In recent years,perovskite solar cells(PSCs)have garnered significant attention as a potential mainstream technology in the future photovol-taic(PV)market.This is primarily attributed to their salient advantages including high efficiency,low cost,and ease of preparation.Nota-bly,the power conversion efficiency(PCE)of PSCs has experienced a remarkable increase from 3.8%in 2009 to over 26%at present.Conse-quently,the adoption of roll-to-roll(R2R)technology for PSCs is considered a crucial step towards their successful commercialization.This arti-de reviews the diverse substrates,scalable deposition techniques(such as solution-based knife-coating and spraying technology),and optimiza.tion procedures employed in recent years to enhance device performance within the R2R process.Additionally,novel perspectives are presented to enrich the existing knowledge in this field.
基金funded by Key Scientific Research Project of Higher Education in Henan Province(22B230010)National College Student Innovation and Entrepreneurship Training Program(202111071002).
文摘Objective The aim of this study was to explore the action mechanism of Sanhua decoction in treating ischemic stroke through network pharmacology and molecular docking technology.Methods Active components and related targets of Sanhua decoction were obtained from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform.A“drug-active component-target”network was constructed,and core components were selected throughtopological analysis.Disease targets related to ischemic stroke were screened based on the Online Mendelian Inheritance in Man(OMIM),Therapeutic Target Database(TTD),GeneCards,DrugBank,and PharmGKB databases.The intersection of active component–related targets and ischemic stroke disease targets was identified to obtain potential targets of Sanhua decoction for treating ischemic stroke,represented using a Venn diagram.The STRING database was used to construct a protein–protein interaction(PPI)network of potential targets and filter for core targets.Gene Ontology(GO)functional enrichment analysis and Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway enrichment analysis of core targets were performed using the DAVID database and Metascape platform.Molecular docking verification of core targets and core components was conducted using AutoDock.Results A total of 52 active components and 142 related targets were screened from Sanhua decoction,with core active components including luteolin,nobiletin,β-sitosterol,eucalyptol,and aloe-emodin.There were 2,991 ischemic stroke–related targets,with 98 potential targets identified in the intersection with active component–related targets.An analysis of the PPI network analysis revealed 23 core targets,including serine/threonine-protein kinase 1(AKT1),tumor protein p53(TP53),and mitogen-activated protein kinase 3(MAPK3).Enrichment analysis obtained 35 GO results and 41 signaling pathways.Molecular docking results indicated good binding between core components and core targets.Conclusion Multiple components in the classic formula Sanhua decoction,such as luteolin and nobiletin,may play a role in treating ischemic stroke by regulating core targets like AKT1,TP53,and MAPK3,and participating in multiple signaling pathways.
文摘In recent years,artificial intelligence technology has developed rapidly around the world is widely used in various fields,and plays an important role.The integration of industrial Internet security with new technologies such as big models and generative artificial intelligence has become a hot research issue.In this regard,this paper briefly analyzes the industrial Internet security technology and application from the perspective of generative artificial intelligence,hoping to provide some valuable reference and reference for readers.
文摘With the continuous development of computer network technology, its applications in daily life and work have become increasingly widespread, greatly improving efficiency. However, certain security risks remain. To ensure the security of computer networks and databases, it is essential to enhance the security of both through optimization of technology. This includes improving management practices, optimizing data processing methods, and establishing comprehensive laws and regulations. This paper analyzes the current security risks in computer networks and databases and proposes corresponding solutions, offering reference points for relevant personnel.
文摘Special Purpose Rice (SPR) is a technology that consists of different rice varieties that were developed by Central Luzon State University. The unique varietal characteristics of SPR are pigmented, glutinous, good-yielding varieties planted in lowland areas. This study was conducted to increase farmers’ income through employing different promotion and extension activities and enterprise development. Data were analyzed using descriptive statistics. Cost and return and benefit-cost analysis were used to determine the financial benefits of using the SPR in different production systems. Results revealed that incorporating the following parameters is critical in the sustainable adoption of the SPR. Amongst them are: ensuring that recommended production technologies are strictly followed by the farmers, ensuring the quality of seeds for planting, the presence of a market for the produce, engaging the farmers in value-adding activities like processing, capability development in entrepreneurship, and adopting clustering approach of the farmers to address economies of scale in marketing and processing. The use of SPR produced an average yield of 6.11 MT/ha and 5.04 MT/ha during the dry and wet seasons from 2021-2023, respectively, higher than the usual varieties of inbred rice. The net benefit from producing a CLS-2 variety of SPR is higher than regular rice, having an average difference of Php 22,355.53 per hectare from 2021-2023.
文摘Cracks are important migration channels and storage spaces for oil and gas, and the peripheral cracks in the Ordos Basin have developed extensively after multiple tectonic movements. Using unmanned aerial vehicle oblique photogrammetry technology to obtain field outcrop image data and establish a three-dimensional model for observation, the NEE and NNW fractures are the most developed in the Yanchang Formation of the study area, while the NW and NNE fractures are slightly developed, all of which are high angle vertical fractures and belong to regional structural fractures. The NNW oriented cracks are restricted by the NEE oriented cracks and developed in the late stage. Combined with the analysis of regional geological background, fracture intersection relationship and tectonic stress field, it is considered that there are two stages of fractures in Dongjiahe, namely, the late Indosinian and Yanshanian.
文摘The integration of digital tools and effective knowledge management practices is critical for enhancing administrative efficiency and institutional continuity in higher education. This study investigates the relationships between knowledge modeling, institutional memory, leadership styles, technology, and administrative efficiency at the University of Cape Coast (UCC). The study sought to identify the challenges and opportunities in integrating digital tools into administrative processes and to provide actionable recommendations for improvement. A mixed-methods research design was employed, combining quantitative analysis using Partial Least Squares Structural Equation Modeling (PLS-SEM) with qualitative thematic analysis of interviews. The findings revealed key challenges, including resistance to change, fragmented knowledge repositories, and inadequate funding, alongside opportunities such as centralized knowledge systems, cost-effective open-source tools, and capacity-building initiatives. The study highlights the importance of strategic leadership, robust policies, and investments in digital infrastructure to enhance administrative practices. Policy implications include the need for clear digital transformation guidelines and leadership training to foster innovation and collaboration. Recommendations include investing in scalable digital tools, implementing comprehensive capacity-building programs, and promoting stakeholder engagement to drive successful digital integration. These insights provide a roadmap for UCC and similar institutions seeking to optimize administrative efficiency through digital transformation.
基金supported by the National Natural Science Foundation of China(NSFC)under the following projects:“Towards High-Quality Technological Innovation in Chinese Cities:Measurement,Mechanism,and Effects”(Grant No.72073093)“Implementation Effects and Micro-Mechanisms of China’s Industrial Policy:A Study of the Steel Industry from the Perspective of Implementation Mechanisms”(Grant No.72373160)“Research on Capital Circles and Enterprise Innovation Quality:Mechanisms and Economic Effects”(Grant No.71872150).
文摘The world today is undergoing disruptive,transformative shifts driven by a new wave of technological revolutions and industrial changes.In this context,a central question for China’s innovation-driven development strategy is how to effectively identify and measure high-quality technological innovations.Drawing on the stylized facts and scenario narrative of China’s technological landscape,this paper proposes a framework and measurement system for evaluating high-quality technological innovations.While China’s top-level design for technological innovation is guided by policy documents,the increasing number of enterprises applying for“high-tech enterprise”status has coincided with a decline in the quality of patent filings.In response,this paper first underscores the challenges and necessity of measuring the quality of technological innovations.Second,we introduce the high-quality technological innovation indicators and employ them to assess the quality of tech innovations at the firm level,utilizing an approach that combines analogical narrative,gene coding,text analysis,semantic logic,and a database of granted invention patents in China.Third,we examine the systematic and individual biases inherent in citation counts,a commonly used indicator,under specific contexts,and employ a granular instrumental variable approach to validate the effectiveness of the indicators.Finally,we develop a“family tree”of the indicators and explore their application scenarios through a combination of established and extended indicators.Our findings provide a theoretical foundation for evaluating China’s technological innovation quality,inform policy incentives,and offer insights for academia to apply high-quality technological innovation indicators in different contexts.
文摘High-power laser technology is widely used in manufacturing processing,medical diagnosis,and treatment,and is one of the important fields of strategic high-tech competition in China at the moment.In the context of industrial upgrading,high-power laser technology plays an important role in leading the development of the manufacturing industry and industrial intelligence.Based on this,this paper carries out research on high-power laser technology and industry,summarizes the basic principle and classification of high-power laser technology,analyzes the current status of high-power laser technology industry,points out the opportunities and challenges faced by the industry development,puts forward suggestions to promote the development of high-power laser technology industry,and to provide an effective reference for the application and development of high-power laser technology.
文摘This paper systematically elucidates the application of plasma technology in cancer treatment,including its principles,case studies,comparative advantages over traditional methods,challenges,and countermeasures.Plasma technology targets and eliminates cancer cells with precision through physical,chemical,and immune-regulatory mechanisms,offering high accuracy and low side effects.International applications include plasma scalpels in the United States,combined chemotherapy and low-temperature plasma therapy in Russia,and plasma-targeted capture technology in China.However,plasma technology faces technical hurdles and clinical application barriers,requiring interdisciplinary collaboration and industry-academia-research cooperation to advance its development.
文摘With the advent of the information age,people’s production and life are more closely connected with the Internet.Internet technology not only improves the production efficiency,but also provides great convenience for people’s life.At present,people’s requirements for computer information technology are gradually increasing.When we look directly at the information transmission and storage capacity,computer information technology cannot meet the market demand.Due to rapid development,the integration of artificial intelligence(AI)can enable the development of computer information technology.In this paper,computer information technology and artificial intelligence integration act as a starting point,and the integration of the development of the two is analyzed for reference.
基金supported by the National Natural Science Foundation of China(No.12071047,51774289,52074291).
文摘To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-mining technology system with non-pillar in mines(ETSNM)in recent years.The petal warning criterion for the stability of the surrounding rock of the roadway at the end-mining stage was obtained by studying the inverse problem of the petal theorem.A conformal mathematical model of the end-mining stage was established using the conformal mapping method,and the limit theorem of the peak point of mine pressure(LTPPMP)in the end-mining stage was demonstrated.Based on the cross-fusion of the above basic mathematical theory and the LTPPMP,a new ETSNM model was proposed,which includes no coal pillar,no dedicated retracement roadways,and fast retracement equipment(NNF).The mathematical principles of engineering technology for height control,speed limit,and roof cutting in the end-mining stage with non-pillar were revealed.The scientific and application values of the ETSNM were confirmed through engineering applications.Based on this,a new non-pillar control technology for dynamic disasters in the end-mining stage was proposed.The above research will play an active role in promoting the engineering application of ETSNM driven by mathematical theory.
基金2023 Xi’an Fanyi University-Level Education and Teaching Reform Research Project“Research on Information Technology-Based Innovative Model of Civics and Politics in the Advanced French Course”(J23B17)。
文摘The Advanced French course is a core subject for the major of French,and ideological and political education is an important component of its teaching.By restructuring the teaching content according to the educational modules of ideological and political education,we can provide a more comprehensive and systematic educational experience.Empowered by information technology,this approach broadens the dimensions of ideological and political education in the Advanced French course.Meanwhile,the learning outcomes from the“first classroom”can be transformed into the results of the“second classroom”through social platforms such as WeChat public accounts,micro-video competitions,and innovation projects,achieving the effect of spreading Chinese culture and telling Chinese stories.By using diverse evaluation criteria,we continuously improve teaching and learning activities and innovate the teaching model of ideological and political education.
文摘As one of the commonly used technologies in modern civil engineering,the construction technology is becoming more and more widely used with the continuous growth of building height.In the construction process of highrise buildings,the deep foundation pit support provides the necessary stability for the foundation structure of the building project,and more effectively guarantees the quality of the project.Through the reasonable supporting structure,the deep foundation pit technology can effectively prevent the risk of soil collapse,foundation pit deformation and other risks,and improve the safety factor of the whole construction project.Especially in the high-rise buildings,the deep foundation pit support technology can consolidate the foundation for the long-term stability of the project,and significantly prolong the service life of the building.The continuous development of deep foundation pit construction technology is the inevitable demand of high-rise building construction,and also provides a powerful help for the development of civil engineering industry.Based on this,this paper focuses on the application of deep foundation pit construction technology in civil engineering construction.
基金Science and Technology Major Project of Xinjiang Uygur Autonomous Region(2020A03003-7)Fundamental Research on Natural Science Program of Shaanxi Province(2021JM-180)+2 种基金Fundamental Research Funds for the Central Universities,CHD(Project for Leading Talents)(300102211302)Tianshan Cedar Plan of Science and Technology Department of Xinjiang Uygur Autonomous Region(2017XS13)Shaanxi Province Young Talent Lifting Program(CLGC202219).
文摘When the expressway crosses the goafs inevitably,the design is generally to build the road on coal pillars as much as possible.However,the existing coal pillars are often unable to meet relevant requirements of highway construction.Combining three-dimensional physical model tests,numerical simulations and fi eld monitoring,with the Urumqi East Second Ring Road passing through acute inclined goafs as a background,the deformation and failure mechanism of the overlying rock and coal pillars in acute inclined goafs under expressway load were studied.And in accordance with construction requirements of subgrade,comprehensive consideration of the deformation and instability mechanism of acute inclined goafs,the treatment measures and suggestions for this type of geological disasters were put forward.The research results confi rmed the rationality of coal pillars in acute inclined goafs under the expressway through grouting.According to the ratio of diff erent overlying rock thickness to coal pillar height,the change trend and value of the required grouting range were summarized,which can provide reference for similar projects.
