This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and pract...This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).展开更多
Some aspects of the robot application in the iron and steel industry were introduced.Even though many successful robot systems improved automation and human-machine operation in iron plants,based on the characteristic...Some aspects of the robot application in the iron and steel industry were introduced.Even though many successful robot systems improved automation and human-machine operation in iron plants,based on the characteristics of the iron and steel industry,difficulties remain for robot applications that are different from other industries.Research and development for robot application is necessary to promote more robots that help personnel work.Furthermore,some key points,new applications,and technological innovation need to be focused on.展开更多
Some of the progress made in our laboratories in collaboration with industry in research and development work on high performance oxide-nonoxide composites for metallurgical applications has been reviewed. （1） SiAlO...Some of the progress made in our laboratories in collaboration with industry in research and development work on high performance oxide-nonoxide composites for metallurgical applications has been reviewed. （1） SiAlON bonded corundum composites for blast furnace usage have been produced by reduction-nitridation sinte-ring at high temperature, using bauxite instead of alu-mina in the matrix. （2） Low carbon Al2O3 - SiAlON slide plate materials successfully used in high quality steel continuous casting have been developed in which most or all of the graphite in Al2O3 - C brick is replaced by bauxite-based β-SiAlON. （3） A1/Si metal bonded A12 03 - C material characterized by low carbon content, low firing temperature and in-situ formation of carbides and nitrides at high temperature during service are found to possess very high hot strength and very good thermal shock resistance and have also been successfully used as slide plates in ladles and tundishes for high quality steel casting.展开更多
Baoshan Iron ＆ Steel Co.,Ltd., （referred to as Baosteel） in China first succeeded in developing the U-ing-O- ing-Expanding （UOE） longitudinal submerged arc welded pipes （SAWLs） offshore linepipe of a maximum th...Baoshan Iron ＆ Steel Co.,Ltd., （referred to as Baosteel） in China first succeeded in developing the U-ing-O- ing-Expanding （UOE） longitudinal submerged arc welded pipes （SAWLs） offshore linepipe of a maximum thickness/ outside diameter （T/D） 0.042 in 2011. Described in this paper is the research and development of the X70 UOE SAWL pipes by the company. The result shows that the said X70 linepipe has been in compliance with relevant requirements as specified in Specifications DNV-OS-F101 ,and has been successfully used in the South China Sea deepwater gas pipeline project.展开更多
Anticancer drugs research and development have been the largest market area in the pharmaceutical industry in terms of the number of project, clinical trials and spending. In the last 10 - 30 years, targeting therapy ...Anticancer drugs research and development have been the largest market area in the pharmaceutical industry in terms of the number of project, clinical trials and spending. In the last 10 - 30 years, targeting therapy for cancers has been developed and achieved enormous clinical effectiveness by transforming some previously deadly malignancies into chronically manageable conditions, but cure problem still remains. This mini review outlined the current status of anticancer drugs development and hinted the opinions of how to further increase the accuracy and efficacy of discovery for cancer treatment.展开更多
In 1981,Nanyang Technological Institute was established in Singapore to train engineers and accountants to keep up with the fast-growing economy of the country.In 1991,the institute was upgraded to Nanyang Technologic...In 1981,Nanyang Technological Institute was established in Singapore to train engineers and accountants to keep up with the fast-growing economy of the country.In 1991,the institute was upgraded to Nanyang Technological University(NTU).NTU holds the rank for world's top young university for six consecutive years according to the Quacquarelli Symonds(QS)world university ranking.Virtual Reality(VR)research began in NTU in the late 1990s.NTU's colleges,schools,institutes,and centers have contributed toward the excellence of VR research.This article briefly describes the VR research directions and activities in NTU.展开更多
The full name of CISRI is Central Iron&Steel Research Institute under the Ministry of Metallurgical Industry in China.It is the largest institute of metallurgical process research in China(the word"large"...The full name of CISRI is Central Iron&Steel Research Institute under the Ministry of Metallurgical Industry in China.It is the largest institute of metallurgical process research in China(the word"large"here refers to various fields,large personnel and many research projects).It includes ironmaking,steel-making,cold and hot processing of steel,metallic product,ferroalloy,refractory,automatic metallurgy control,design展开更多
Broadband Wireless Access (BWA) has become one of the major evolution trends in the fields of broadband access and mobile communications. However,some difficulties emerged during the application and industrialization ...Broadband Wireless Access (BWA) has become one of the major evolution trends in the fields of broadband access and mobile communications. However,some difficulties emerged during the application and industrialization of the BWA system,which calls for typical service models,key technology innovations and backbone support from broadband Internet. This article introduces a Broadband Wireless Multimedia (BWM) access system. It aims to build a new-type "triple play" BWA network by integrating terrestrial digital TV system and the BWA system,and by taking broadband Internet as its core network platform. A primary research shows that the new BWA system is an effective solution to the existing difficulties of BWA system. Moreover,it is quite competitive in service provision,service coverage,frequency planning,terminal power consumption and cost for network construction.展开更多
Tsinghua-TOYO Research and Development Center of Magnesium and Aluminum Alloys Processing Technology was officially established between Tsinghua University and TOYO Machinery & Metal Co. on Feb. 26, 2002, which is...Tsinghua-TOYO Research and Development Center of Magnesium and Aluminum Alloys Processing Technology was officially established between Tsinghua University and TOYO Machinery & Metal Co. on Feb. 26, 2002, which is a non-independent legal research organization located in Department of Mechanical Engineering of Tsinghua University. The center was equipped with one set of 650t automatic magnesium and aluminum alloys diecasting machine and necessary accessories including the melting furnaces for magnesium alloys and aluminum alloys, an accurate magnesium pump to transfer the magnesium alloys to the shot sleeve of the die casting machine, a die temperature controller, and data logging systems for cavity pressure and die temperature distributions, etc. The center is aimed to the research and development of magnesium and aluminum die casting process and their related technologies, and the main research contents include:展开更多
The Institute for Agricultural Research,Samaru,has the national mandate for genetic improvement and development of production technologies for cotton,maize,sorghum,cowpea,groundnut,
Pharmaceutical technology is an indispensable and important link in drug research and development,which plays a key role in drug research and development quality.In the background of science and technology development...Pharmaceutical technology is an indispensable and important link in drug research and development,which plays a key role in drug research and development quality.In the background of science and technology development,pharmaceutical technology has been greatly developed,but also to promote the quality of drug research and development,to provide more guarantee for people’s health.In the new era,how to achieve pharmaceutical technology innovation,so as to further improve the quality of drug research and development,is an important research topic in the current related industries.This paper mainly revolves around quality of pharmaceutical technology development of a series of exploration,in the traditional drug development based on a better control of drug quality,the future of smart pharmaceutical green pharmaceutical development direction,aims to further enhance the pharmaceutical technology,promote the quality of research and development to promote the comprehensive,promote the steady development of the pharmaceutical industry as a whole.展开更多
There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical archit...There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical architecture is selected to design and develop the POB plan management module applicable to offshore platform facilities. The main functions of this module include task management, facility management, area management, sea-going unit management, plan management, report management, authority control, and comprehensive query. It can efficiently solve on-site business problems and improve the efficiency of POB plan management for various professionals on land and at sea. In actual use, the module can well assist in completing POB plan management tasks and improve work efficiency.展开更多
With the rapid development of China's economy, the demand for automobiles is increasing, and the quality requirements are getting higher and higher. Developing high-quality automobile products is a major topic of ...With the rapid development of China's economy, the demand for automobiles is increasing, and the quality requirements are getting higher and higher. Developing high-quality automobile products is a major topic of project planning and management. In this paper, the automobile project management is deeply studied, and through the analysis and summary of the problems existing in daily work, improvement measures and suggestions are put forward. Doing things according to the rules, emphasizing planning, building processes, unifying thoughts, managing projects with adaptive teams, grasping critical paths, controlling costs, mastering core delivery and performance acceptance, etc., can solve the pain points of automobile project management, and gradually form a method and theory combined with practice, thus contributing to the collective wisdom of project management.展开更多
As far as Chinese herbal medicine resources are concerned,China is one of the countries with the richest biodiversity in the world.As for the future development direction of Chinese skin care products,the development ...As far as Chinese herbal medicine resources are concerned,China is one of the countries with the richest biodiversity in the world.As for the future development direction of Chinese skin care products,the development of special Chinese herbal skin care products is an important issue.The technical route for the research and development(R&D)of Chinese herbal-medicine skin care products should focus on“combining ancient and modern,combining Chinese and Western”,that is to say combining the ancient knowledge and wisdom with modern science and technology,and combining Chinese traditional therapy with western pharmacology.This article will elaborate the five stages of developing innovative Chinese herbal skin care products:pondering and thinking stage;extraction and purification stage;experimental evaluation stage;quality index establishment stage;product development stage.The key points of these five stages can provide a reference for the cosmetics R&D personnel.This project will be beneficial to the development of Chinese herbal-medicine skin care products and the formulation of an overall effective development strategy,which is helpful to actively respond to new challenges and continuously improve product competitiveness,so as to vigorously build a world-renowned high-end cosmetic brand in China,and strive to cultivate a world-class cosmetics talent team.展开更多
Objective To help investors assess and control the costs of new drug development and reduce the risks of new drug development projects.Methods Cost analysis and financial forecasting were carried out with the integrat...Objective To help investors assess and control the costs of new drug development and reduce the risks of new drug development projects.Methods Cost analysis and financial forecasting were carried out with the integrated approach of earned value management.According to the principle of earned value management deviation analysis,the basic process of the new drug research and development project was combined with the hypothesis method from the research of Tufts Drug Development Research Center.Results and Conclusion If the project progress check was carried out in the clinical trial,the project costs were found overspent,the efficiency was low,the project progress was faster,and the resource investment was ahead.It is recommended that the adjustment should be made to reduce the input of resources,and increase the efficient key personnel to take the place of some less efficient staff.展开更多
The research and development of new traditional Chinese medicine(TCM)drugs have progressively established a novel system founded on the integration of TCM theory,human experience,and clinical trials(termed the“Three ...The research and development of new traditional Chinese medicine(TCM)drugs have progressively established a novel system founded on the integration of TCM theory,human experience,and clinical trials(termed the“Three Combinations”).However,considering TCM's distinctive features of“syndrome differentiation and treatment”and“multicomponent formulations and complex mechanisms”,current TCM drug development faces challenges such as insufficient understanding of the material basis and the overall mechanism of action and an incomplete evidence chain system.Moreover,significant obstacles persist in gathering human experience data,evaluating clinical efficacy,and controlling the quality of active ingredients,which impede the innovation process in TCM drug development.Network pharmacology,centered on the“network targets”theory,transcends the limitations of the conventional“single target”reductionist research model.It emphasizes the comprehensive effects of disease or syndrome biological networks as targets to elucidate the overall regulatory mechanism of TCM prescriptions.This approach aligns with the holistic perspective of TCM,offering a novel method consistent with TCM's holistic view for investigating the complex mechanisms of TCM and developing new TCM drugs.It is internationally recognized as a“next-generation drug research model”.To advance the research of new tools,methods,and standards for TCM evaluation and to overcome fundamental,critical,and cutting-edge technical challenges in TCM regulation,this consensus aims to explore the characteristics,progress,challenges,applicable pathways,and specific applications of network pharmacology as a new theory,method,and tool in TCM drug development.The goal is to enhance the quality of TCM drug research and development and accelerate the efficiency of developing new TCM products.展开更多
文摘This comparative review explores the dynamic and evolving landscape of artificial intelligence(AI)-powered innovations within high-tech research and development(R&D).It delves into both theoreticalmodels and practical applications across a broad range of industries,including biotechnology,automotive,aerospace,and telecom-munications.By examining critical advancements in AI algorithms,machine learning,deep learning models,simulations,and predictive analytics,the review underscores the transformative role AI has played in advancing theoretical research and shaping cutting-edge technologies.The review integrates both qualitative and quantitative data derived from academic studies,industry reports,and real-world case studies to showcase the tangible impacts of AI on product innovation,process optimization,and strategic decision-making.Notably,it discusses the challenges of integrating AI within complex industrial systems,such as ethical concerns,technical limitations,and the need for regulatory oversight.The findings reveal a mixed landscape where AI has significantly accelerated R&D processes,reduced costs,and enabled more precise simulations and predictions,but also highlighted gaps in knowledge transfer,skills adaptation,and cross-industry standardization.By bridging the gap between AI theory and practice,the review offers insights into the effectiveness,successes,and obstacles faced by organizations as they implement AI-driven solutions.Concluding with a forward-looking perspective,the review identifies emerging trends,future challenges,and promising opportunities inAI-poweredR&D,such as the rise of autonomous systems,AI-driven drug discovery,and sustainable energy solutions.It offers a holistic understanding of how AI is shaping the future of technological innovation and provides actionable insights for researchers,engineers,and policymakers involved in high-tech Research and Development(R&D).
文摘Some aspects of the robot application in the iron and steel industry were introduced.Even though many successful robot systems improved automation and human-machine operation in iron plants,based on the characteristics of the iron and steel industry,difficulties remain for robot applications that are different from other industries.Research and development for robot application is necessary to promote more robots that help personnel work.Furthermore,some key points,new applications,and technological innovation need to be focused on.
文摘Some of the progress made in our laboratories in collaboration with industry in research and development work on high performance oxide-nonoxide composites for metallurgical applications has been reviewed. （1） SiAlON bonded corundum composites for blast furnace usage have been produced by reduction-nitridation sinte-ring at high temperature, using bauxite instead of alu-mina in the matrix. （2） Low carbon Al2O3 - SiAlON slide plate materials successfully used in high quality steel continuous casting have been developed in which most or all of the graphite in Al2O3 - C brick is replaced by bauxite-based β-SiAlON. （3） A1/Si metal bonded A12 03 - C material characterized by low carbon content, low firing temperature and in-situ formation of carbides and nitrides at high temperature during service are found to possess very high hot strength and very good thermal shock resistance and have also been successfully used as slide plates in ladles and tundishes for high quality steel casting.
文摘Baoshan Iron ＆ Steel Co.,Ltd., （referred to as Baosteel） in China first succeeded in developing the U-ing-O- ing-Expanding （UOE） longitudinal submerged arc welded pipes （SAWLs） offshore linepipe of a maximum thickness/ outside diameter （T/D） 0.042 in 2011. Described in this paper is the research and development of the X70 UOE SAWL pipes by the company. The result shows that the said X70 linepipe has been in compliance with relevant requirements as specified in Specifications DNV-OS-F101 ,and has been successfully used in the South China Sea deepwater gas pipeline project.
文摘Anticancer drugs research and development have been the largest market area in the pharmaceutical industry in terms of the number of project, clinical trials and spending. In the last 10 - 30 years, targeting therapy for cancers has been developed and achieved enormous clinical effectiveness by transforming some previously deadly malignancies into chronically manageable conditions, but cure problem still remains. This mini review outlined the current status of anticancer drugs development and hinted the opinions of how to further increase the accuracy and efficacy of discovery for cancer treatment.
文摘In 1981,Nanyang Technological Institute was established in Singapore to train engineers and accountants to keep up with the fast-growing economy of the country.In 1991,the institute was upgraded to Nanyang Technological University(NTU).NTU holds the rank for world's top young university for six consecutive years according to the Quacquarelli Symonds(QS)world university ranking.Virtual Reality(VR)research began in NTU in the late 1990s.NTU's colleges,schools,institutes,and centers have contributed toward the excellence of VR research.This article briefly describes the VR research directions and activities in NTU.
文摘The full name of CISRI is Central Iron&Steel Research Institute under the Ministry of Metallurgical Industry in China.It is the largest institute of metallurgical process research in China(the word"large"here refers to various fields,large personnel and many research projects).It includes ironmaking,steel-making,cold and hot processing of steel,metallic product,ferroalloy,refractory,automatic metallurgy control,design
文摘Broadband Wireless Access (BWA) has become one of the major evolution trends in the fields of broadband access and mobile communications. However,some difficulties emerged during the application and industrialization of the BWA system,which calls for typical service models,key technology innovations and backbone support from broadband Internet. This article introduces a Broadband Wireless Multimedia (BWM) access system. It aims to build a new-type "triple play" BWA network by integrating terrestrial digital TV system and the BWA system,and by taking broadband Internet as its core network platform. A primary research shows that the new BWA system is an effective solution to the existing difficulties of BWA system. Moreover,it is quite competitive in service provision,service coverage,frequency planning,terminal power consumption and cost for network construction.
文摘Tsinghua-TOYO Research and Development Center of Magnesium and Aluminum Alloys Processing Technology was officially established between Tsinghua University and TOYO Machinery & Metal Co. on Feb. 26, 2002, which is a non-independent legal research organization located in Department of Mechanical Engineering of Tsinghua University. The center was equipped with one set of 650t automatic magnesium and aluminum alloys diecasting machine and necessary accessories including the melting furnaces for magnesium alloys and aluminum alloys, an accurate magnesium pump to transfer the magnesium alloys to the shot sleeve of the die casting machine, a die temperature controller, and data logging systems for cavity pressure and die temperature distributions, etc. The center is aimed to the research and development of magnesium and aluminum die casting process and their related technologies, and the main research contents include:
文摘The Institute for Agricultural Research,Samaru,has the national mandate for genetic improvement and development of production technologies for cotton,maize,sorghum,cowpea,groundnut,
文摘Pharmaceutical technology is an indispensable and important link in drug research and development,which plays a key role in drug research and development quality.In the background of science and technology development,pharmaceutical technology has been greatly developed,but also to promote the quality of drug research and development,to provide more guarantee for people’s health.In the new era,how to achieve pharmaceutical technology innovation,so as to further improve the quality of drug research and development,is an important research topic in the current related industries.This paper mainly revolves around quality of pharmaceutical technology development of a series of exploration,in the traditional drug development based on a better control of drug quality,the future of smart pharmaceutical green pharmaceutical development direction,aims to further enhance the pharmaceutical technology,promote the quality of research and development to promote the comprehensive,promote the steady development of the pharmaceutical industry as a whole.
文摘There are many access ends and information asymmetry in the management of offshore platform production facility personnel information. In the actual business, the problem is decomposed and a multi-layer logical architecture is selected to design and develop the POB plan management module applicable to offshore platform facilities. The main functions of this module include task management, facility management, area management, sea-going unit management, plan management, report management, authority control, and comprehensive query. It can efficiently solve on-site business problems and improve the efficiency of POB plan management for various professionals on land and at sea. In actual use, the module can well assist in completing POB plan management tasks and improve work efficiency.
文摘With the rapid development of China's economy, the demand for automobiles is increasing, and the quality requirements are getting higher and higher. Developing high-quality automobile products is a major topic of project planning and management. In this paper, the automobile project management is deeply studied, and through the analysis and summary of the problems existing in daily work, improvement measures and suggestions are put forward. Doing things according to the rules, emphasizing planning, building processes, unifying thoughts, managing projects with adaptive teams, grasping critical paths, controlling costs, mastering core delivery and performance acceptance, etc., can solve the pain points of automobile project management, and gradually form a method and theory combined with practice, thus contributing to the collective wisdom of project management.
文摘As far as Chinese herbal medicine resources are concerned,China is one of the countries with the richest biodiversity in the world.As for the future development direction of Chinese skin care products,the development of special Chinese herbal skin care products is an important issue.The technical route for the research and development(R&D)of Chinese herbal-medicine skin care products should focus on“combining ancient and modern,combining Chinese and Western”,that is to say combining the ancient knowledge and wisdom with modern science and technology,and combining Chinese traditional therapy with western pharmacology.This article will elaborate the five stages of developing innovative Chinese herbal skin care products:pondering and thinking stage;extraction and purification stage;experimental evaluation stage;quality index establishment stage;product development stage.The key points of these five stages can provide a reference for the cosmetics R&D personnel.This project will be beneficial to the development of Chinese herbal-medicine skin care products and the formulation of an overall effective development strategy,which is helpful to actively respond to new challenges and continuously improve product competitiveness,so as to vigorously build a world-renowned high-end cosmetic brand in China,and strive to cultivate a world-class cosmetics talent team.
文摘Objective To help investors assess and control the costs of new drug development and reduce the risks of new drug development projects.Methods Cost analysis and financial forecasting were carried out with the integrated approach of earned value management.According to the principle of earned value management deviation analysis,the basic process of the new drug research and development project was combined with the hypothesis method from the research of Tufts Drug Development Research Center.Results and Conclusion If the project progress check was carried out in the clinical trial,the project costs were found overspent,the efficiency was low,the project progress was faster,and the resource investment was ahead.It is recommended that the adjustment should be made to reduce the input of resources,and increase the efficient key personnel to take the place of some less efficient staff.
基金supported by the National Medical Products Administration Commissioned Research Project (No.20211440216)the National Administration of Traditional Chinese Medicine Science and Technology Project (No.GZY-KJS-2024-03)+3 种基金the State Key Laboratory of Drug Regulatory Science Project (No.2023SKLDRS0104)the Basic Research Program Natural Science Fund-Frontier Leading Technology Basic Research Special Project of Jiangsu Province (No.BK20232014)the Programs Foundation for Leading Talents in National Administration of Traditional Chinese Medicine of China“Qihuang scholars”Projectthe Tianjin Administration for Market Regulation Science and Technology Key Projects (No.2022-W35)。
文摘The research and development of new traditional Chinese medicine(TCM)drugs have progressively established a novel system founded on the integration of TCM theory,human experience,and clinical trials(termed the“Three Combinations”).However,considering TCM's distinctive features of“syndrome differentiation and treatment”and“multicomponent formulations and complex mechanisms”,current TCM drug development faces challenges such as insufficient understanding of the material basis and the overall mechanism of action and an incomplete evidence chain system.Moreover,significant obstacles persist in gathering human experience data,evaluating clinical efficacy,and controlling the quality of active ingredients,which impede the innovation process in TCM drug development.Network pharmacology,centered on the“network targets”theory,transcends the limitations of the conventional“single target”reductionist research model.It emphasizes the comprehensive effects of disease or syndrome biological networks as targets to elucidate the overall regulatory mechanism of TCM prescriptions.This approach aligns with the holistic perspective of TCM,offering a novel method consistent with TCM's holistic view for investigating the complex mechanisms of TCM and developing new TCM drugs.It is internationally recognized as a“next-generation drug research model”.To advance the research of new tools,methods,and standards for TCM evaluation and to overcome fundamental,critical,and cutting-edge technical challenges in TCM regulation,this consensus aims to explore the characteristics,progress,challenges,applicable pathways,and specific applications of network pharmacology as a new theory,method,and tool in TCM drug development.The goal is to enhance the quality of TCM drug research and development and accelerate the efficiency of developing new TCM products.
