Calcium ferrite(CF)is recognized as a potential green and efficient functional material because of its advantages of magnetism,electrochemistry,catalysis,and biocompatibility in the fields of materials chemistry,envir...Calcium ferrite(CF)is recognized as a potential green and efficient functional material because of its advantages of magnetism,electrochemistry,catalysis,and biocompatibility in the fields of materials chemistry,environmental engineering,and biomedicine.There-fore,the obtained research results need to be systematically summarized,and new perspectives on CF and its composite materials need to be analyzed.Based on the presented studies of CF and its composite materials,the types and structures of the crystal are summarized.In addition,the current application technologies and theoretical mechanisms with various properties in different fields are elucidated.Moreover,the various preparation methods of CF and its composite materials are elaborated in detail.Most importantly,the advantages and disadvantages of the synthesis methods of CF and its composite materials are discussed,and the existing problems and emerging challenges in practical production are identified.Furthermore,the key future research directions of CF and its composite materials have been prospected from the potential application technologies to provide references for its synthesis and efficient utilization.展开更多
Concerns about air quality in dental clinics where aerosol generation during procedures poses significant health risks,have prompted investigations on advanced disinfection technologies.This editorial describes the st...Concerns about air quality in dental clinics where aerosol generation during procedures poses significant health risks,have prompted investigations on advanced disinfection technologies.This editorial describes the strengths and limitations of ventilation and aerosol control measures in dental offices,especially with respect to the use of graphene nanocomposites.The potential of graphene nanocomposites as an innovative solution to aerosol-associated health risks is examined in this review due to the unique properties of graphene(e.g.,high con-ductivity,mechanical strength,and antimicrobial activity).These properties have produced promising results in various fields,but the application of graphene in dentistry remains unexplored.The recent study by Ju et al which was published in World Journal of Clinical Cases evaluated the effectiveness of graphene-based air disinfection systems in dental clinics.The study demonstrated that graphene-based disinfection techniques produced significant reductions in suspended particulate matter and bacterial colony counts,when co-mpared with traditional methods.Despite these positive results,challenges such as material saturation,frequency of filter replacement,and associated costs must be addressed before widespread adoption of graphene-based disinfection techniques in clinical practice.Therefore,there is need for further research on material structure optimization,long-term safety evaluations,and broader clinical applications,in order to maximize their positive impact on public health.展开更多
Theoretical education and practical education are very important in clinical laboratory teaching.The teaching evaluation system is one of the important means to test the quality of course teaching.The traditional summ...Theoretical education and practical education are very important in clinical laboratory teaching.The teaching evaluation system is one of the important means to test the quality of course teaching.The traditional summative evaluation needs to be improved in terms of scientificity and impartiality,and its guiding effect on teaching reform is limited.Therefore,this paper proposes to apply formative evaluation to clinical laboratory teaching to remobilize students'learning enthusiasm and provide valuable guidance for the subsequent teaching reform,hoping to achieve the purpose of improving the quality of laboratory teaching.展开更多
With the rapid development of generative artificial intelligence(AI)technology in the field of education,global educational systems are facing unprecedented opportunities and challenges,urgently requiring the establis...With the rapid development of generative artificial intelligence(AI)technology in the field of education,global educational systems are facing unprecedented opportunities and challenges,urgently requiring the establishment of comprehensive,flexible,and forward-looking governance solutions.The“Australian Framework for Generative AI in Schools”builds a multi-dimensional governance system covering aspects such as teaching and humanistic care,fairness and transparency,and accountability and security.Based on 22 specific principles and six core elements,it emphasizes a human-centered design concept,adopts a principle-based flexible structure,focuses on fairness and transparency,and stresses accountability and security.The framework provides valuable references for the use of generative AI in China’s education system and holds significant importance for promoting educational modernization and cultivating innovative talents adapted to the era of artificial intelligence.展开更多
The Health Action Process Approach(HAPA),developed by German psychologist Schwarzer in the 1980s,provides a comprehensive framework for understanding and influencing health behavior change.By dividing behavior change ...The Health Action Process Approach(HAPA),developed by German psychologist Schwarzer in the 1980s,provides a comprehensive framework for understanding and influencing health behavior change.By dividing behavior change into three dynamic stages-pre-intention,intention,and action-HAPA highlights the critical role of self-efficacy as a driving force in adopting healthier behaviors.This stage-based approach addresses the limitations of continuous health behavior models by emphasizing individual differentiation and recognizing that behavior change is not linear but progresses through distinct phases.HAPA theory has demonstrated significant potential in clinical applications,particularly in orthopedic postoperative patients.Its implementation facilitates the development of positive behavioral intentions,enhances self-efficacy,and supports sustained health action,ultimately improving patients’health outcomes and quality of life.Tailored interventions based on HAPA stages ensure that patients receive appropriate guidance and support throughout their recovery journey.Despite its successes,limitations remain.Future research should focus on expanding the application of HAPA to various orthopedic conditions and developing more targeted behavioral plans and health education programs to optimize patient rehabilitation.Additionally,further exploration is needed to sustain HAPA’s effectiveness during long-term recovery.Strengthening interdisciplinary collaboration and integrating HAPA with other theoretical models could create a more comprehensive health behavior education system,providing robust support for orthopedic patients and advancing their overall recovery and well-being.展开更多
With the advancement of the modernization of traditional Chinese medicine(TCM),TCM granules have emerged and garnered widespread attention.This study provides a comprehensive review of the development of TCM granules,...With the advancement of the modernization of traditional Chinese medicine(TCM),TCM granules have emerged and garnered widespread attention.This study provides a comprehensive review of the development of TCM granules,analyzing their characteristics in terms of ease of use,quality stability,and pharmacodynamic advantages.It also explores their broad application prospects in clinical TCM treatment and preventive healthcare.Through an integrative analysis of relevant research literature,the study highlights the significant value and vast development potential of TCM granules in modern medicine.The article aims to offer valuable references for the modernization and internationalization of TCM while promoting the continuous development and innovative application of TCM granules in the field of traditional Chinese medicine.展开更多
Nucleic acid analysis is a key technique that enables accurate detection of various microorganisms.Conventional nucleic acid testing typically requires access to specialized laboratories,equipment,and trained personne...Nucleic acid analysis is a key technique that enables accurate detection of various microorganisms.Conventional nucleic acid testing typically requires access to specialized laboratories,equipment,and trained personnel,which hinders the widespread use of on-site testing for DNA and RNA targets.However,integrating gene editing technology with traditional nucleic acid detection methods,especially isothermal amplification technology,can help overcome the limitations associated with on-site testing.This combination can accomplish precise and swift detection of nucleic acid sequences,offering a robust tool for on-site detection.The Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated proteins(CRISPR/Cas)technology,which comprises the CRISPR system and Cas effector proteins,is a powerful tool that is advancing the field of nucleic acid detection.Specifically,Cas12,Cas13,and Cas14 proteins have emerged as straightforward,effective,precise,sensitive,and cost-effective methods for in vitro nucleic acid detection because of their“collateral cleavage”characteristics.When combined with the“collateral cleavage”ability of Cas protein and isothermal amplification,CRISPR/Cas systems have great potential to advance nucleic acid detection.This article summarizes the research progress of different CRISPR/Cas systems and their applications in nucleic acid detection and future perspectives.展开更多
Zinc oxide(ZnO),as a broadband gap semiconductor material,exhibits unique physical and chemical properties that make it highly suitable for optoelectronics,piezoelectric devices,and gas-sensitive sensors,showing signi...Zinc oxide(ZnO),as a broadband gap semiconductor material,exhibits unique physical and chemical properties that make it highly suitable for optoelectronics,piezoelectric devices,and gas-sensitive sensors,showing significant potential for various applications.This paper focuses on the regulation and application of ZnO-based p-n junctions and piezoelectric devices.It discusses in detail the preparation of ZnO materials,the construction of p-n junctions,the optimization of piezoelectric device performance,and its application in various fields.By employing different preparation methods and strategies,high-quality ZnO thin films can be grown,and effective control of p-type conductivity achieved.This study provides both a theoretical foundation and technical support for controlling the performance of ZnO-based piezoelectric devices,as well as paving new pathways for the broader application of ZnO materials.展开更多
Objective:To analyze the application value of a non-catheter tampon in abdominal hysterectomy,providing a reference for related research.Methods:A total of 100 patients were included in this study,with data collected ...Objective:To analyze the application value of a non-catheter tampon in abdominal hysterectomy,providing a reference for related research.Methods:A total of 100 patients were included in this study,with data collected between January 4,2022,and January 4,2024.The patients were divided into two groups:the new group and the traditional group,each comprising 50 patients.Results:Compared with the traditional group,the new group demonstrated significantly lower intraoperative blood loss(P<0.05).Additionally,the incidence of complications,operation time,hospital stay,time required to resume normal activities,and postoperative VAS scores were all significantly lower in the new group(P<0.05).Conclusion:The application of a non-catheter tampon during abdominal hysterectomy yields satisfactory results.This approach is worthy of further clinical promotion and application.展开更多
To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-minin...To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-mining technology system with non-pillar in mines(ETSNM)in recent years.The petal warning criterion for the stability of the surrounding rock of the roadway at the end-mining stage was obtained by studying the inverse problem of the petal theorem.A conformal mathematical model of the end-mining stage was established using the conformal mapping method,and the limit theorem of the peak point of mine pressure(LTPPMP)in the end-mining stage was demonstrated.Based on the cross-fusion of the above basic mathematical theory and the LTPPMP,a new ETSNM model was proposed,which includes no coal pillar,no dedicated retracement roadways,and fast retracement equipment(NNF).The mathematical principles of engineering technology for height control,speed limit,and roof cutting in the end-mining stage with non-pillar were revealed.The scientific and application values of the ETSNM were confirmed through engineering applications.Based on this,a new non-pillar control technology for dynamic disasters in the end-mining stage was proposed.The above research will play an active role in promoting the engineering application of ETSNM driven by mathematical theory.展开更多
College English teaching is a crucial component of higher education.Enhancing college students’English learning outcomes has long been a primary focus for educators.With the continuous evolution of educational philos...College English teaching is a crucial component of higher education.Enhancing college students’English learning outcomes has long been a primary focus for educators.With the continuous evolution of educational philosophies,traditional college English teaching methods no longer meet the learning needs of contemporary students.Situational cognitive learning theory emphasizes learner-centered approaches and highlights the contextual and practical application of knowledge,offering innovative perspectives for reforming college English teaching.When applied effectively,situational cognitive learning theory can optimize teaching methods and significantly improve learning outcomes.This paper explores the connotation and characteristics of situational cognitive learning theory,evaluates its applicability in college English teaching,and discusses its practical implementation in this context.The aim is to provide theoretical and practical references for improving the quality of college English education.展开更多
The application of generative artificial intelligence(GAI)in the judicial domain represents an innovative approach to achieving digital justice.GAI’s functionalities are primarily exhibited in the enhancement of judi...The application of generative artificial intelligence(GAI)in the judicial domain represents an innovative approach to achieving digital justice.GAI’s functionalities are primarily exhibited in the enhancement of judicial efficiency,improving the accuracy and fairness of adjudications,promoting the uniform application of the law,and enhancing transparency and engagement in judicial processes.However,these advancements are accompanied by potential risks and challenges in technology,adjudication,and ethics.It is thus essential to strengthen privacy protection during the processing and transmission of data,ensure data security and confidentiality,and establish and refine clear legal norms regarding the roles,responsibilities,and legal obligations of GAI in judicial settings.In addition,ethical guidelines that delineate the behavioral boundaries and value orientations of GAI need to be formulated.Collectively,these elements can form a trinary model of technical controls,legal norms,and ethical constraints,to facilitate the modernization and intelligent development of the judicial system.展开更多
As one of the commonly used technologies in modern civil engineering,the construction technology is becoming more and more widely used with the continuous growth of building height.In the construction process of highr...As one of the commonly used technologies in modern civil engineering,the construction technology is becoming more and more widely used with the continuous growth of building height.In the construction process of highrise buildings,the deep foundation pit support provides the necessary stability for the foundation structure of the building project,and more effectively guarantees the quality of the project.Through the reasonable supporting structure,the deep foundation pit technology can effectively prevent the risk of soil collapse,foundation pit deformation and other risks,and improve the safety factor of the whole construction project.Especially in the high-rise buildings,the deep foundation pit support technology can consolidate the foundation for the long-term stability of the project,and significantly prolong the service life of the building.The continuous development of deep foundation pit construction technology is the inevitable demand of high-rise building construction,and also provides a powerful help for the development of civil engineering industry.Based on this,this paper focuses on the application of deep foundation pit construction technology in civil engineering construction.展开更多
Exosomes(Exos)are extracellular vesicles secreted by cells and serve as crucial mediators of intercellular communication.They play a pivotal role in the pathogenesis and progression of various diseases and offer promi...Exosomes(Exos)are extracellular vesicles secreted by cells and serve as crucial mediators of intercellular communication.They play a pivotal role in the pathogenesis and progression of various diseases and offer promising avenues for therapeutic interventions.Exos derived from mesenchymal stem cells(MSCs)have significant immunomodulatory properties.They effectively regulate immune responses by modulating both innate and adaptive immunity.These Exos can inhibit excessive inflammatory responses and promote tissue repair.Moreover,they participate in antigen presentation,which is essential for activating immune responses.The cargo of these Exos,including ligands,proteins,and microRNAs,can suppress T cell activity or enhance the population of immunosuppressive cells to dampen the immune response.By inhibiting lymphocyte proliferation,acting on macrophages,and increasing the population of regulatory T cells,these Exos contribute to maintaining immune and metabolic homeostasis.Furthermore,they can activate immune-related signaling pathways or serve as vehicles to deliver microRNAs and other bioactive substances to target tumor cells,which holds potential for immunotherapy applications.Given the immense therapeutic potential of MSC-derived Exos,this review comprehensively explores their mechanisms of immune regulation and therapeutic applications in areas such as infection control,tumor suppression,and autoimmune disease management.This article aims to provide valuable insights into the mechanisms behind the actions of MSC-derived Exos,offering theoretical references for their future clinical utilization as cell-free drug preparations.展开更多
Grape crops are a great source of income for farmers.The yield and quality of grapes can be improved by preventing and treating diseases.The farmer’s yield will be dramatically impacted if diseases are found on grape...Grape crops are a great source of income for farmers.The yield and quality of grapes can be improved by preventing and treating diseases.The farmer’s yield will be dramatically impacted if diseases are found on grape leaves.Automatic detection can reduce the chances of leaf diseases affecting other healthy plants.Several studies have been conducted to detect grape leaf diseases,but most fail to engage with end users and integrate the model with real-time mobile applications.This study developed a mobile-based grape leaf disease detection(GLDD)application to identify infected leaves,Grape Guard,based on a TensorFlow Lite(TFLite)model generated from the You Only Look Once(YOLO)v8 model.A public grape leaf disease dataset containing four classes was used to train the model.The results of this study were relied on the YOLO architecture,specifically YOLOv5 and YOLOv8.After extensive experiments with different image sizes,YOLOv8 performed better than YOLOv5.YOLOv8 achieved 99.9%precision,100%recall,99.5%mean average precision(mAP),and 88%mAP50-95 for all classes to detect grape leaf diseases.The Grape Guard android mobile application can accurately detect the grape leaf disease by capturing images from grape vines.展开更多
Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hosp...Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hospital treatment from July to October 2022 were selected and randomly divided into an observation group and a control group, with 100 patients in each group. Patients in the control group received routine nursing methods, while those in the observation group were managed using the safety risk management method of the infusion project team. The tube blocking rate and tube removal rate were compared between the two groups. Results: The one-time puncture success rate and the standard implementation rate of intravenous indwelling needle use in the observation group were significantly higher than those in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group, and patient satisfaction in the observation group was notably higher, with statistically significant differences (P < 0.05). Conclusion: The application of an infusion project team in the safety risk management of indwelling needle use is effective and has positive impacts on improving the one-time puncture success rate, the standard implementation rate of intravenous indwelling needle use, and patient satisfaction. It is a practice worth promoting in clinical settings.展开更多
Moringa oleifera Lam.is a Moringa genus in the Moringaceae family that is high in nutrients and has a wide range of applications.Phenolic compounds are widely found in plants and have various health benefits for the h...Moringa oleifera Lam.is a Moringa genus in the Moringaceae family that is high in nutrients and has a wide range of applications.Phenolic compounds are widely found in plants and have various health benefits for the human body.With its high content and wide variety of phenolic compounds,M.oleifera Lam.has been widely studied for its health benefits.The phenolic compounds in M.oleifera Lam.(MOPCs)can be a potential source of functional food ingredients in pharmaceutical and industrial applications.Numerous studies have shown that MOPCs have antioxidant,anti-obesity,anti-diabetic,and antibacterial effects.Although the research on MOPCs has been gradually increasing,the extraction,isolation,identification,biological activities,and comprehensive application of MOPCs need a more systematic summary and generalization.Therefore,this paper reviews the isolation and extraction methods,structure identification,biological activities,and comprehensive applications to provide a further reference for the research and application of MOPCs.展开更多
Lonicera japonica(honeysuckle)is a traditional Chinese medicinal food,in which the main active ingredients are phenolic acids,polysaccharides,flavonoids,and volatile oils.They have various biological activities,includ...Lonicera japonica(honeysuckle)is a traditional Chinese medicinal food,in which the main active ingredients are phenolic acids,polysaccharides,flavonoids,and volatile oils.They have various biological activities,including antiviral,antibacterial,antioxidant,hypoglycemic and lipid-lowering,and anti-inflammatory effects.This review summarizes the health effects and pharmacodynamic mechanisms of L.japonica extracts and the major active ingredients in these extracts,and the structures,metabolic process in vivo,and biotransformation processes of these compounds.In addition,the current status of the development of L.japonica-related functional foods is summarized.The aim is to provide a theoretical basis and reference for the further development and use of the active ingredients in L.japonica as functional foods for disease prevention and treatment.展开更多
Objective: To analyze the clinical effects of the patient participation health model in the health management of type 2 diabetes mellitus. Methods: A total of 124 patients with type 2 diabetes admitted to the hospital...Objective: To analyze the clinical effects of the patient participation health model in the health management of type 2 diabetes mellitus. Methods: A total of 124 patients with type 2 diabetes admitted to the hospital from June 2023 to June 2024 were randomly assigned to either the control group (64 patients) or the intervention group (60 patients). Patients in the control group received routine health management, while those in the intervention group were managed using a patient-participation health model with progressive, stage-based interventions. Outcomes were assessed based on blood glucose control, disease awareness, and self-management behaviors. Adverse reactions during health management were closely monitored in both groups. Results: Patients in the intervention group showed significantly better outcomes in blood glucose control, disease awareness, and self-management behaviors compared to the control group. Conclusion: The patient participation health model demonstrated significant clinical value, effectively enhancing self-management abilities, improving glycemic control, and increasing disease awareness. This model is recommended for widespread adoption in the health management of type 2 diabetes to achieve better therapeutic outcomes and improve patient quality of life.展开更多
This study focuses on the teaching reform of the communication application development course based on the core requirements of engineering education accreditation.To address key challenges such as the disconnection b...This study focuses on the teaching reform of the communication application development course based on the core requirements of engineering education accreditation.To address key challenges such as the disconnection between software and hardware teaching and insufficient practical skills among students,a project-driven“learning-practiceapplication”teaching model is proposed.By optimizing course content,innovating teaching methods,and introducing university-industry collaboration mechanisms,the reform aligns the curriculum more closely with engineering education standards and industry demands.The approach significantly enhances students’comprehensive skills,practical abilities,and employability.This study provides theoretical foundations and practical strategies for the teaching reform of courses in communication engineering.展开更多
基金supported by the National Natural Science Foundation of China(No.51574105)the Science and Technology Program of Hebei Province,China(No.23564101D)+2 种基金the Natural Science Foundation of Hebei Province,China(No.E2021209147)the Key Research Project of North China University of Science and Technology(No.ZD-ST-202308)the Postgraduate Innovation Funding Project of Hebei Province,China(No.CXZZBS2024135).
文摘Calcium ferrite(CF)is recognized as a potential green and efficient functional material because of its advantages of magnetism,electrochemistry,catalysis,and biocompatibility in the fields of materials chemistry,environmental engineering,and biomedicine.There-fore,the obtained research results need to be systematically summarized,and new perspectives on CF and its composite materials need to be analyzed.Based on the presented studies of CF and its composite materials,the types and structures of the crystal are summarized.In addition,the current application technologies and theoretical mechanisms with various properties in different fields are elucidated.Moreover,the various preparation methods of CF and its composite materials are elaborated in detail.Most importantly,the advantages and disadvantages of the synthesis methods of CF and its composite materials are discussed,and the existing problems and emerging challenges in practical production are identified.Furthermore,the key future research directions of CF and its composite materials have been prospected from the potential application technologies to provide references for its synthesis and efficient utilization.
文摘Concerns about air quality in dental clinics where aerosol generation during procedures poses significant health risks,have prompted investigations on advanced disinfection technologies.This editorial describes the strengths and limitations of ventilation and aerosol control measures in dental offices,especially with respect to the use of graphene nanocomposites.The potential of graphene nanocomposites as an innovative solution to aerosol-associated health risks is examined in this review due to the unique properties of graphene(e.g.,high con-ductivity,mechanical strength,and antimicrobial activity).These properties have produced promising results in various fields,but the application of graphene in dentistry remains unexplored.The recent study by Ju et al which was published in World Journal of Clinical Cases evaluated the effectiveness of graphene-based air disinfection systems in dental clinics.The study demonstrated that graphene-based disinfection techniques produced significant reductions in suspended particulate matter and bacterial colony counts,when co-mpared with traditional methods.Despite these positive results,challenges such as material saturation,frequency of filter replacement,and associated costs must be addressed before widespread adoption of graphene-based disinfection techniques in clinical practice.Therefore,there is need for further research on material structure optimization,long-term safety evaluations,and broader clinical applications,in order to maximize their positive impact on public health.
文摘Theoretical education and practical education are very important in clinical laboratory teaching.The teaching evaluation system is one of the important means to test the quality of course teaching.The traditional summative evaluation needs to be improved in terms of scientificity and impartiality,and its guiding effect on teaching reform is limited.Therefore,this paper proposes to apply formative evaluation to clinical laboratory teaching to remobilize students'learning enthusiasm and provide valuable guidance for the subsequent teaching reform,hoping to achieve the purpose of improving the quality of laboratory teaching.
基金2024 Undergraduate Innovation Training Program Project“Research on the Current Situation,Impact and Management Countermeasures of Generative AI in College Students’Learning”(202410065153)。
文摘With the rapid development of generative artificial intelligence(AI)technology in the field of education,global educational systems are facing unprecedented opportunities and challenges,urgently requiring the establishment of comprehensive,flexible,and forward-looking governance solutions.The“Australian Framework for Generative AI in Schools”builds a multi-dimensional governance system covering aspects such as teaching and humanistic care,fairness and transparency,and accountability and security.Based on 22 specific principles and six core elements,it emphasizes a human-centered design concept,adopts a principle-based flexible structure,focuses on fairness and transparency,and stresses accountability and security.The framework provides valuable references for the use of generative AI in China’s education system and holds significant importance for promoting educational modernization and cultivating innovative talents adapted to the era of artificial intelligence.
基金Youth Project of Inner Mongolia Medical University in 2022(YKD2022QN020)。
文摘The Health Action Process Approach(HAPA),developed by German psychologist Schwarzer in the 1980s,provides a comprehensive framework for understanding and influencing health behavior change.By dividing behavior change into three dynamic stages-pre-intention,intention,and action-HAPA highlights the critical role of self-efficacy as a driving force in adopting healthier behaviors.This stage-based approach addresses the limitations of continuous health behavior models by emphasizing individual differentiation and recognizing that behavior change is not linear but progresses through distinct phases.HAPA theory has demonstrated significant potential in clinical applications,particularly in orthopedic postoperative patients.Its implementation facilitates the development of positive behavioral intentions,enhances self-efficacy,and supports sustained health action,ultimately improving patients’health outcomes and quality of life.Tailored interventions based on HAPA stages ensure that patients receive appropriate guidance and support throughout their recovery journey.Despite its successes,limitations remain.Future research should focus on expanding the application of HAPA to various orthopedic conditions and developing more targeted behavioral plans and health education programs to optimize patient rehabilitation.Additionally,further exploration is needed to sustain HAPA’s effectiveness during long-term recovery.Strengthening interdisciplinary collaboration and integrating HAPA with other theoretical models could create a more comprehensive health behavior education system,providing robust support for orthopedic patients and advancing their overall recovery and well-being.
文摘With the advancement of the modernization of traditional Chinese medicine(TCM),TCM granules have emerged and garnered widespread attention.This study provides a comprehensive review of the development of TCM granules,analyzing their characteristics in terms of ease of use,quality stability,and pharmacodynamic advantages.It also explores their broad application prospects in clinical TCM treatment and preventive healthcare.Through an integrative analysis of relevant research literature,the study highlights the significant value and vast development potential of TCM granules in modern medicine.The article aims to offer valuable references for the modernization and internationalization of TCM while promoting the continuous development and innovative application of TCM granules in the field of traditional Chinese medicine.
基金supported by the Natural Science Foundation of Hunan Province(Grant Nos.2021JJ30050 and 2023JJ50368)Science and Technology Program of Hunan Province(Grant No.2021SK50313)+3 种基金the Research Project of Hunan Provincial Health Commission(Grant Nos.202203102912 and 202203103105,W20243264)the Science and Technology Program of Chenzhou(Grant No.ZDYF2020011)the Key Project of the First People’s Hospital of Chenzhou(Grant No.CZYY202203)the Innovative Team Project of the First People’s Hospital of Chenzhou(Grant No.CX202103).
文摘Nucleic acid analysis is a key technique that enables accurate detection of various microorganisms.Conventional nucleic acid testing typically requires access to specialized laboratories,equipment,and trained personnel,which hinders the widespread use of on-site testing for DNA and RNA targets.However,integrating gene editing technology with traditional nucleic acid detection methods,especially isothermal amplification technology,can help overcome the limitations associated with on-site testing.This combination can accomplish precise and swift detection of nucleic acid sequences,offering a robust tool for on-site detection.The Clustered Regularly Interspaced Short Palindromic Repeats/CRISPR-associated proteins(CRISPR/Cas)technology,which comprises the CRISPR system and Cas effector proteins,is a powerful tool that is advancing the field of nucleic acid detection.Specifically,Cas12,Cas13,and Cas14 proteins have emerged as straightforward,effective,precise,sensitive,and cost-effective methods for in vitro nucleic acid detection because of their“collateral cleavage”characteristics.When combined with the“collateral cleavage”ability of Cas protein and isothermal amplification,CRISPR/Cas systems have great potential to advance nucleic acid detection.This article summarizes the research progress of different CRISPR/Cas systems and their applications in nucleic acid detection and future perspectives.
基金The Natural Science Foundation of Guangdong Province(Project No.2023A1515012352)。
文摘Zinc oxide(ZnO),as a broadband gap semiconductor material,exhibits unique physical and chemical properties that make it highly suitable for optoelectronics,piezoelectric devices,and gas-sensitive sensors,showing significant potential for various applications.This paper focuses on the regulation and application of ZnO-based p-n junctions and piezoelectric devices.It discusses in detail the preparation of ZnO materials,the construction of p-n junctions,the optimization of piezoelectric device performance,and its application in various fields.By employing different preparation methods and strategies,high-quality ZnO thin films can be grown,and effective control of p-type conductivity achieved.This study provides both a theoretical foundation and technical support for controlling the performance of ZnO-based piezoelectric devices,as well as paving new pathways for the broader application of ZnO materials.
文摘Objective:To analyze the application value of a non-catheter tampon in abdominal hysterectomy,providing a reference for related research.Methods:A total of 100 patients were included in this study,with data collected between January 4,2022,and January 4,2024.The patients were divided into two groups:the new group and the traditional group,each comprising 50 patients.Results:Compared with the traditional group,the new group demonstrated significantly lower intraoperative blood loss(P<0.05).Additionally,the incidence of complications,operation time,hospital stay,time required to resume normal activities,and postoperative VAS scores were all significantly lower in the new group(P<0.05).Conclusion:The application of a non-catheter tampon during abdominal hysterectomy yields satisfactory results.This approach is worthy of further clinical promotion and application.
基金supported by the National Natural Science Foundation of China(No.12071047,51774289,52074291).
文摘To ameliorate the difficulties of on-site dynamic disaster control in the end-mining stage of traditional mining engineering,this paper introduces the mathematical research and engineering application of the end-mining technology system with non-pillar in mines(ETSNM)in recent years.The petal warning criterion for the stability of the surrounding rock of the roadway at the end-mining stage was obtained by studying the inverse problem of the petal theorem.A conformal mathematical model of the end-mining stage was established using the conformal mapping method,and the limit theorem of the peak point of mine pressure(LTPPMP)in the end-mining stage was demonstrated.Based on the cross-fusion of the above basic mathematical theory and the LTPPMP,a new ETSNM model was proposed,which includes no coal pillar,no dedicated retracement roadways,and fast retracement equipment(NNF).The mathematical principles of engineering technology for height control,speed limit,and roof cutting in the end-mining stage with non-pillar were revealed.The scientific and application values of the ETSNM were confirmed through engineering applications.Based on this,a new non-pillar control technology for dynamic disasters in the end-mining stage was proposed.The above research will play an active role in promoting the engineering application of ETSNM driven by mathematical theory.
文摘College English teaching is a crucial component of higher education.Enhancing college students’English learning outcomes has long been a primary focus for educators.With the continuous evolution of educational philosophies,traditional college English teaching methods no longer meet the learning needs of contemporary students.Situational cognitive learning theory emphasizes learner-centered approaches and highlights the contextual and practical application of knowledge,offering innovative perspectives for reforming college English teaching.When applied effectively,situational cognitive learning theory can optimize teaching methods and significantly improve learning outcomes.This paper explores the connotation and characteristics of situational cognitive learning theory,evaluates its applicability in college English teaching,and discusses its practical implementation in this context.The aim is to provide theoretical and practical references for improving the quality of college English education.
文摘The application of generative artificial intelligence(GAI)in the judicial domain represents an innovative approach to achieving digital justice.GAI’s functionalities are primarily exhibited in the enhancement of judicial efficiency,improving the accuracy and fairness of adjudications,promoting the uniform application of the law,and enhancing transparency and engagement in judicial processes.However,these advancements are accompanied by potential risks and challenges in technology,adjudication,and ethics.It is thus essential to strengthen privacy protection during the processing and transmission of data,ensure data security and confidentiality,and establish and refine clear legal norms regarding the roles,responsibilities,and legal obligations of GAI in judicial settings.In addition,ethical guidelines that delineate the behavioral boundaries and value orientations of GAI need to be formulated.Collectively,these elements can form a trinary model of technical controls,legal norms,and ethical constraints,to facilitate the modernization and intelligent development of the judicial system.
文摘As one of the commonly used technologies in modern civil engineering,the construction technology is becoming more and more widely used with the continuous growth of building height.In the construction process of highrise buildings,the deep foundation pit support provides the necessary stability for the foundation structure of the building project,and more effectively guarantees the quality of the project.Through the reasonable supporting structure,the deep foundation pit technology can effectively prevent the risk of soil collapse,foundation pit deformation and other risks,and improve the safety factor of the whole construction project.Especially in the high-rise buildings,the deep foundation pit support technology can consolidate the foundation for the long-term stability of the project,and significantly prolong the service life of the building.The continuous development of deep foundation pit construction technology is the inevitable demand of high-rise building construction,and also provides a powerful help for the development of civil engineering industry.Based on this,this paper focuses on the application of deep foundation pit construction technology in civil engineering construction.
基金Supported by the National Natural Science Foundation of China,No.82072537the General Project of Hunan Natural Science Foundation,No.2022JJ30412 and No.2021JJ30464.
文摘Exosomes(Exos)are extracellular vesicles secreted by cells and serve as crucial mediators of intercellular communication.They play a pivotal role in the pathogenesis and progression of various diseases and offer promising avenues for therapeutic interventions.Exos derived from mesenchymal stem cells(MSCs)have significant immunomodulatory properties.They effectively regulate immune responses by modulating both innate and adaptive immunity.These Exos can inhibit excessive inflammatory responses and promote tissue repair.Moreover,they participate in antigen presentation,which is essential for activating immune responses.The cargo of these Exos,including ligands,proteins,and microRNAs,can suppress T cell activity or enhance the population of immunosuppressive cells to dampen the immune response.By inhibiting lymphocyte proliferation,acting on macrophages,and increasing the population of regulatory T cells,these Exos contribute to maintaining immune and metabolic homeostasis.Furthermore,they can activate immune-related signaling pathways or serve as vehicles to deliver microRNAs and other bioactive substances to target tumor cells,which holds potential for immunotherapy applications.Given the immense therapeutic potential of MSC-derived Exos,this review comprehensively explores their mechanisms of immune regulation and therapeutic applications in areas such as infection control,tumor suppression,and autoimmune disease management.This article aims to provide valuable insights into the mechanisms behind the actions of MSC-derived Exos,offering theoretical references for their future clinical utilization as cell-free drug preparations.
文摘Grape crops are a great source of income for farmers.The yield and quality of grapes can be improved by preventing and treating diseases.The farmer’s yield will be dramatically impacted if diseases are found on grape leaves.Automatic detection can reduce the chances of leaf diseases affecting other healthy plants.Several studies have been conducted to detect grape leaf diseases,but most fail to engage with end users and integrate the model with real-time mobile applications.This study developed a mobile-based grape leaf disease detection(GLDD)application to identify infected leaves,Grape Guard,based on a TensorFlow Lite(TFLite)model generated from the You Only Look Once(YOLO)v8 model.A public grape leaf disease dataset containing four classes was used to train the model.The results of this study were relied on the YOLO architecture,specifically YOLOv5 and YOLOv8.After extensive experiments with different image sizes,YOLOv8 performed better than YOLOv5.YOLOv8 achieved 99.9%precision,100%recall,99.5%mean average precision(mAP),and 88%mAP50-95 for all classes to detect grape leaf diseases.The Grape Guard android mobile application can accurately detect the grape leaf disease by capturing images from grape vines.
文摘Objective: To explore the effectiveness of applying an infusion project team in the safety risk management of indwelling needle use. Methods: A total of 200 patients who used intravenous indwelling needles during hospital treatment from July to October 2022 were selected and randomly divided into an observation group and a control group, with 100 patients in each group. Patients in the control group received routine nursing methods, while those in the observation group were managed using the safety risk management method of the infusion project team. The tube blocking rate and tube removal rate were compared between the two groups. Results: The one-time puncture success rate and the standard implementation rate of intravenous indwelling needle use in the observation group were significantly higher than those in the control group. The total incidence of complications in the observation group was significantly lower than that in the control group, and patient satisfaction in the observation group was notably higher, with statistically significant differences (P < 0.05). Conclusion: The application of an infusion project team in the safety risk management of indwelling needle use is effective and has positive impacts on improving the one-time puncture success rate, the standard implementation rate of intravenous indwelling needle use, and patient satisfaction. It is a practice worth promoting in clinical settings.
基金supported by Major Project of Science and Technology Department of Yunnan Province(202002AA100005,202102AE090027-2)National Natural Science Foundation of China(82260703)+1 种基金Cassava Industrial Technology System of China(CARS11-YNTY)Yunnan Province Ten Thousand Plan Industrial Technology Talents Project(YNWR-CYJS-2020-010)。
文摘Moringa oleifera Lam.is a Moringa genus in the Moringaceae family that is high in nutrients and has a wide range of applications.Phenolic compounds are widely found in plants and have various health benefits for the human body.With its high content and wide variety of phenolic compounds,M.oleifera Lam.has been widely studied for its health benefits.The phenolic compounds in M.oleifera Lam.(MOPCs)can be a potential source of functional food ingredients in pharmaceutical and industrial applications.Numerous studies have shown that MOPCs have antioxidant,anti-obesity,anti-diabetic,and antibacterial effects.Although the research on MOPCs has been gradually increasing,the extraction,isolation,identification,biological activities,and comprehensive application of MOPCs need a more systematic summary and generalization.Therefore,this paper reviews the isolation and extraction methods,structure identification,biological activities,and comprehensive applications to provide a further reference for the research and application of MOPCs.
基金supports from the National Natural Science Foundation of China(82130112,U24A20789)Beijing Hospitals Authority Ascent Plan(DFL20190702)Youth Beijing Scholar(2022-051)。
文摘Lonicera japonica(honeysuckle)is a traditional Chinese medicinal food,in which the main active ingredients are phenolic acids,polysaccharides,flavonoids,and volatile oils.They have various biological activities,including antiviral,antibacterial,antioxidant,hypoglycemic and lipid-lowering,and anti-inflammatory effects.This review summarizes the health effects and pharmacodynamic mechanisms of L.japonica extracts and the major active ingredients in these extracts,and the structures,metabolic process in vivo,and biotransformation processes of these compounds.In addition,the current status of the development of L.japonica-related functional foods is summarized.The aim is to provide a theoretical basis and reference for the further development and use of the active ingredients in L.japonica as functional foods for disease prevention and treatment.
文摘Objective: To analyze the clinical effects of the patient participation health model in the health management of type 2 diabetes mellitus. Methods: A total of 124 patients with type 2 diabetes admitted to the hospital from June 2023 to June 2024 were randomly assigned to either the control group (64 patients) or the intervention group (60 patients). Patients in the control group received routine health management, while those in the intervention group were managed using a patient-participation health model with progressive, stage-based interventions. Outcomes were assessed based on blood glucose control, disease awareness, and self-management behaviors. Adverse reactions during health management were closely monitored in both groups. Results: Patients in the intervention group showed significantly better outcomes in blood glucose control, disease awareness, and self-management behaviors compared to the control group. Conclusion: The patient participation health model demonstrated significant clinical value, effectively enhancing self-management abilities, improving glycemic control, and increasing disease awareness. This model is recommended for widespread adoption in the health management of type 2 diabetes to achieve better therapeutic outcomes and improve patient quality of life.
基金Quality Engineering Project of Higher Education Institutions in Anhui Province(2023aqnujyxm26,2023sx060,2023zyxwjxalk124)Natural Science Key Research Project for Higher Education Institutions of Anhui Province(2024AH051117,2024AH051126)+1 种基金Excellent Young Backbone Teachers’Domestic and Foreign Visiting and Training Program in Universities(gxgnfx20220262022)Research and Industrialization Project of High Precision Positioning System for Intelligent Connected Vehicles。
文摘This study focuses on the teaching reform of the communication application development course based on the core requirements of engineering education accreditation.To address key challenges such as the disconnection between software and hardware teaching and insufficient practical skills among students,a project-driven“learning-practiceapplication”teaching model is proposed.By optimizing course content,innovating teaching methods,and introducing university-industry collaboration mechanisms,the reform aligns the curriculum more closely with engineering education standards and industry demands.The approach significantly enhances students’comprehensive skills,practical abilities,and employability.This study provides theoretical foundations and practical strategies for the teaching reform of courses in communication engineering.
