Let p and q be two distinct primes, epq（n） denotes the largest exponent of power pq which divides n. In this paper, we study the mean value properties of function epq（n）, and give some hybrid mean value formulas f...Let p and q be two distinct primes, epq（n） denotes the largest exponent of power pq which divides n. In this paper, we study the mean value properties of function epq（n）, and give some hybrid mean value formulas for epq（n） and Dirichlet divisor function d（n）. Key words： largest exponent; asymptotic formula; hybrid mean value; Dirichlet divisor function d（n）展开更多
目的分析外周血同型半胱氨酸(homocysteine,Hcy)、D-二聚体(D-dimer,D-D)、中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)结合血小板与淋巴细胞比值(platelet to lymphocyte ratio,PLR)对急性脑梗死溶栓治疗后复发的...目的分析外周血同型半胱氨酸(homocysteine,Hcy)、D-二聚体(D-dimer,D-D)、中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)结合血小板与淋巴细胞比值(platelet to lymphocyte ratio,PLR)对急性脑梗死溶栓治疗后复发的预测价值。方法选取2020年3月-2022年3月周口市中心医院收治的急性脑梗死患者367例,均行静脉溶栓治疗;出院后随访1年,根据患者脑梗死有无复发将其分为复发组和未复发组,比较两组入院次日外周血Hcy、D-D、NLR、PLR及其他临床资料;采用logistic回归分析法分析急性脑梗死溶栓治疗后复发的影响因素,另采用受试者工作特征曲线分析外周血Hcy、D-D、NLR、PLR单项及联合对急性脑梗死溶栓治疗后复发的预测价值。结果复发组的高血压患者占比、低密度脂蛋白胆固醇(low density lipoprotein-cholesterol,LDL-C)水平、Hcy水平、D-D水平、NLR、PLR均高于未复发组(P<0.05);高血压、LDL-C、Hcy、D-D、NLR及PLR均为急性脑梗死溶栓治疗后复发的影响因素(P<0.05);外周血Hcy、D-D、NLR、PLR联合预测急性脑梗死溶栓治疗后复发的敏感度和曲线下面积高于单独预测(P<0.05),特异度与单独预测差异无统计学意义(P>0.05)。结论外周血LDL-C、Hcy、D-D、NLR、PLR均为急性脑梗死溶栓治疗后复发的影响因素,并对脑梗死复发具有一定的预测价值,且上述指标联合预测的效能更高。展开更多
With more ready-to-eat foods and increased shelf-lives, prevention of Listeria monocytogenes contamination has become a necessity for the food industry. This study examined the effects of sublethal heat treatment on t...With more ready-to-eat foods and increased shelf-lives, prevention of Listeria monocytogenes contamination has become a necessity for the food industry. This study examined the effects of sublethal heat treatment on the decimal reduction time (D-values) of three L. monocytogenes serotypes (1/2a, 1/2b, 4c), and non-pathogenic L. innocua. The D70 (D-value at 70℃) values of heat-shocked (HS) and non-heat-shocked (NHS) Listeria grown in tryptic soy broth (TSB) were determined. The D70 values of HS L. monocytogenes serotype 1/2a and L. innocua were significantly higher compared to NHS cultures, although by 48 h, the values returned to NHS levels. When HS and NHS 1/2a and 1/2b were inoculated on crab meat and cooked shrimp, the D70 values of HS cultures were at least 2-fold higher, compared to when they were grown in TSB. This increase in heat resistance for the HS cultures may be attributed to the protective effect of the seafood matrix itself.展开更多
目的分析联合检测D-二聚体、白细胞介素-6(interleukin-6,IL-6)及纤维蛋白原(fibrinogen,FIB)诊断急性胰腺炎的价值。方法回顾性分析2021年1月—2023年9月厦门大学附属中山医院救治的164例急性胰腺炎患者。根据急性胰腺炎病情的严重程...目的分析联合检测D-二聚体、白细胞介素-6(interleukin-6,IL-6)及纤维蛋白原(fibrinogen,FIB)诊断急性胰腺炎的价值。方法回顾性分析2021年1月—2023年9月厦门大学附属中山医院救治的164例急性胰腺炎患者。根据急性胰腺炎病情的严重程度进行分组,即轻症急性胰腺炎组(n=67)、中度重症急性胰腺炎组(n=47)、重症急性胰腺炎组(n=50);同时选择同期200名健康者设为对照组。所有患者均于入院48 h内测定D-二聚体、IL-6、FIB水平,并进行对比;同时阐明D-二聚体、IL-6、FIB单一检测及联合检测对诊断急性胰腺炎的临床意义与价值。结果4组D-二聚体、IL-6、FIB水平比较,差异有统计学意义(P<0.05)。D-二聚体、IL-6、FIB水平均与急性胰腺炎病情严重程度呈正相关(P<0.05)。D-二聚体的曲线下面积(area under curve,AUC)、敏感度、特异度分别为0.941、86.57%、99.00%;IL-6的AUC、敏感度、特异度分别为0.844、79.10%、98.50%;FIB的AUC、敏感度、特异度分别为0.789、68.66%、81.00%;联合检测的AUC、敏感度、特异度分别为0.974、92.54%、93.00%。结论D-二聚体、IL-6、FIB均可用于急性胰腺炎的诊断中,且上述指标水平的变化与急性胰腺炎病情具有相关性,同时联合检测更有助于减少漏诊、误诊的发生。展开更多
文摘Let p and q be two distinct primes, epq（n） denotes the largest exponent of power pq which divides n. In this paper, we study the mean value properties of function epq（n）, and give some hybrid mean value formulas for epq（n） and Dirichlet divisor function d（n）. Key words： largest exponent; asymptotic formula; hybrid mean value; Dirichlet divisor function d（n）
文摘目的分析外周血同型半胱氨酸(homocysteine,Hcy)、D-二聚体(D-dimer,D-D)、中性粒细胞与淋巴细胞比值(neutrophil to lymphocyte ratio,NLR)结合血小板与淋巴细胞比值(platelet to lymphocyte ratio,PLR)对急性脑梗死溶栓治疗后复发的预测价值。方法选取2020年3月-2022年3月周口市中心医院收治的急性脑梗死患者367例,均行静脉溶栓治疗;出院后随访1年,根据患者脑梗死有无复发将其分为复发组和未复发组,比较两组入院次日外周血Hcy、D-D、NLR、PLR及其他临床资料;采用logistic回归分析法分析急性脑梗死溶栓治疗后复发的影响因素,另采用受试者工作特征曲线分析外周血Hcy、D-D、NLR、PLR单项及联合对急性脑梗死溶栓治疗后复发的预测价值。结果复发组的高血压患者占比、低密度脂蛋白胆固醇(low density lipoprotein-cholesterol,LDL-C)水平、Hcy水平、D-D水平、NLR、PLR均高于未复发组(P<0.05);高血压、LDL-C、Hcy、D-D、NLR及PLR均为急性脑梗死溶栓治疗后复发的影响因素(P<0.05);外周血Hcy、D-D、NLR、PLR联合预测急性脑梗死溶栓治疗后复发的敏感度和曲线下面积高于单独预测(P<0.05),特异度与单独预测差异无统计学意义(P>0.05)。结论外周血LDL-C、Hcy、D-D、NLR、PLR均为急性脑梗死溶栓治疗后复发的影响因素,并对脑梗死复发具有一定的预测价值,且上述指标联合预测的效能更高。
文摘With more ready-to-eat foods and increased shelf-lives, prevention of Listeria monocytogenes contamination has become a necessity for the food industry. This study examined the effects of sublethal heat treatment on the decimal reduction time (D-values) of three L. monocytogenes serotypes (1/2a, 1/2b, 4c), and non-pathogenic L. innocua. The D70 (D-value at 70℃) values of heat-shocked (HS) and non-heat-shocked (NHS) Listeria grown in tryptic soy broth (TSB) were determined. The D70 values of HS L. monocytogenes serotype 1/2a and L. innocua were significantly higher compared to NHS cultures, although by 48 h, the values returned to NHS levels. When HS and NHS 1/2a and 1/2b were inoculated on crab meat and cooked shrimp, the D70 values of HS cultures were at least 2-fold higher, compared to when they were grown in TSB. This increase in heat resistance for the HS cultures may be attributed to the protective effect of the seafood matrix itself.
文摘目的分析联合检测D-二聚体、白细胞介素-6(interleukin-6,IL-6)及纤维蛋白原(fibrinogen,FIB)诊断急性胰腺炎的价值。方法回顾性分析2021年1月—2023年9月厦门大学附属中山医院救治的164例急性胰腺炎患者。根据急性胰腺炎病情的严重程度进行分组,即轻症急性胰腺炎组(n=67)、中度重症急性胰腺炎组(n=47)、重症急性胰腺炎组(n=50);同时选择同期200名健康者设为对照组。所有患者均于入院48 h内测定D-二聚体、IL-6、FIB水平,并进行对比;同时阐明D-二聚体、IL-6、FIB单一检测及联合检测对诊断急性胰腺炎的临床意义与价值。结果4组D-二聚体、IL-6、FIB水平比较,差异有统计学意义(P<0.05)。D-二聚体、IL-6、FIB水平均与急性胰腺炎病情严重程度呈正相关(P<0.05)。D-二聚体的曲线下面积(area under curve,AUC)、敏感度、特异度分别为0.941、86.57%、99.00%;IL-6的AUC、敏感度、特异度分别为0.844、79.10%、98.50%;FIB的AUC、敏感度、特异度分别为0.789、68.66%、81.00%;联合检测的AUC、敏感度、特异度分别为0.974、92.54%、93.00%。结论D-二聚体、IL-6、FIB均可用于急性胰腺炎的诊断中,且上述指标水平的变化与急性胰腺炎病情具有相关性,同时联合检测更有助于减少漏诊、误诊的发生。
