Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming t...Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming to summarize the results of prior primary research studies on available evidence Community type 2 diabetes structured education (CT2DSHE). Methods: Research question: Type 2 diabetic structured health education within a community how effective is it? Qualitative Systematic review, defined as a way to get reliable and objective picture of current available evidence on the specific topic—(CT2DSHE), (Denscombe, 2021) through reflexivity synthesis of available data as an example. This is valuable in time constraints such as project assignments that must be met within specific time and also to bring together available evidence together [1]. Results: This review has shown that CT2DSHE is effective with seven out of the eleven authors supporting, three authors against and one was neutral, further showed that knowledge and skills acquired can last longer with patient activation improved among T2DM patients ideal for sustaining their self-management of T2DM. Conclusion: This research provides suggestive answers to the research question: “Type 2 diabetic structured health education within a community how effective is it?”, This has demonstrated CT2DSHE effectiveness in knowledge acquisition and improving T2DM awareness among T2DM patients, whilst evidencing long effects beyond the study times of 3 - 9 months period in relation to patient activation. Also Identified diabetes education self-management on newly diagnosed (DESMOND) patient as CT2DSHE program for recommendation. Patient or Public Contribution: This work aspires to contribute to CT2DSHE in these areas;Influencing policy decision-making for community diabetes care within the UK and world at large., Contributing to already vast knowledge on diabetes self-management and reasons why?, Influencing educators on how CT2DSHEP are designed, delivered by putting the patient at the Centre and bringing different perspectives on CT2DSHEP in one place that is serving users time of having to consult several resources especially busy clinicians [2] [3].展开更多
A genistein derivative, 5-hydroxy-3-（4-hydroxyphenyl）-7-（2-（piperidin- 1-yl）ethoxy）- 4H-chromen-4-one 3, was designed, prepared and structurally characterized by single-crystal X-ray diffraction. X-ray structure...A genistein derivative, 5-hydroxy-3-（4-hydroxyphenyl）-7-（2-（piperidin- 1-yl）ethoxy）- 4H-chromen-4-one 3, was designed, prepared and structurally characterized by single-crystal X-ray diffraction. X-ray structure analysis reveals that 3 crystallizes in the orthorhombic system, space group Pbca, with a = 16.238（3）, b = 10.308（2）, c = 22.987（5）A, V = 3847.6（13）A3, Z = 8,μ= 0.093 mm^-1, Dc = 1.317 g/cm^3, F（000） = 1616, R = 0.0789 and wR = 0.1554 for 1463 observed reflections with I 〉 2σ（I）.展开更多
A new hydrogen bonded Cobalt(II) Schiff base complex,?N’-(pyridine-4-carboxaldehyde) isonicotinoylhydrazone Cobalt(II), has been synthesized from isoniazid and pyridine-4-carboxaldehyde and characterized by IR spectr...A new hydrogen bonded Cobalt(II) Schiff base complex,?N’-(pyridine-4-carboxaldehyde) isonicotinoylhydrazone Cobalt(II), has been synthesized from isoniazid and pyridine-4-carboxaldehyde and characterized by IR spectroscopy, 1H-NMR, elemental analysis, TGA and single crystal X-ray structure determination. X-ray crystal structure analysis shows an octahedral complex with a metal centre coordinated to two ligand molecules through the pyridine nitrogen atoms and four water molecules and containing two nitrate groups as counter ions. The complex crystallizes in the monoclinic crystal system and P2(1)/n space group. The unit cell dimensions are: a = 7.2108(4) Å, b = 16.6020(9) Å, c = 13.0389(6) Å,α = 90°, β = 103.972(4)°, γ = 90°. The molecule is symmetrical about the cobalt centre as observed from the 1H-NMR and 13C-NMR and confirmed by the single crystal X-ray structure of the complex. Thermogravimetric analysis shows two steps decomposition of the complex to leave a metal oxide residue. The title compound is expected to be biologically active as one of the precursors (isoniazid) is a therapeutic agent with well-established clinical applications.展开更多
A new chain-like coordination polymer, namely, [CuL]n （1, Na2L = 2-[（2-hydroxy- benzylidene）-amino]-benzenesulfonic acid sodium salt）, has been synthesized and characterized by single-crystal X-ray diffraction, IR...A new chain-like coordination polymer, namely, [CuL]n （1, Na2L = 2-[（2-hydroxy- benzylidene）-amino]-benzenesulfonic acid sodium salt）, has been synthesized and characterized by single-crystal X-ray diffraction, IR spectroscopy and elemental analysis. Complex 1 crystallizes in monoclinic system, space group P21/c with a = 9.2296（16）, b = 10.4754（18）, c = 12.200（2） A, β = 102.392（2）°, V = 1152.0（3）A3, CI3H9CuNOaN, Mr = 338.83, Dc = 1.953 g/cm3, Z = 4, F（000） = 684, p = 2.089 mm-1, the final R = 0.0376 and wR = 0.0956. X-ray diffraction analyses indicate that 1 displays a square-pyramidal metal center with NO4 donor sets. The sulfonate-derived Schiff base serves as a common N,O,O＇-tridentate and a unique O-bridged ligand connecting the metals. Dinuclear copper complexes serve as secondary building blocks （SBUs） to construct an unusual 2D coordination network. In the crystal, the components form a stable 3D supramolecular architecture by C-H...O interactions and to-stacking展开更多
Direct kinematics with analytic solutions is critical to the real-time control of parallel mechanisms.Therefore,the type synthesis of a mechanism having explicit form of forward kinematics has become a topic of intere...Direct kinematics with analytic solutions is critical to the real-time control of parallel mechanisms.Therefore,the type synthesis of a mechanism having explicit form of forward kinematics has become a topic of interest.Based on this purpose,this paper deals with the type synthesis of 1T2R parallel mechanisms by investigating the topological structure coupling-reducing of the 3UPS&UP parallel mechanism.With the aid of the theory of mechanism topology,the analysis of the topological characteristics of the 3UPS&UP parallel mechanism is presented,which shows that there are highly coupled motions and constraints amongst the limbs of the mechanism.Three methods for structure coupling-reducing of the 3UPS&UP parallel mechanism are proposed,resulting in eight new types of 1T2R parallel mechanisms with one or zero coupling degree.One obtained parallel mechanism is taken as an example to demonstrate that a mechanism with zero coupling degree has an explicit form for forward kinematics.The process of type synthesis is in the order of permutation and combination;therefore,there are no omissions.This method is also appli cable to other configurations,and novel topological structures having simple forward kinematics can be obtained from an original mechanism via this method.展开更多
A novel imidazole derivative with functional group and π-conjugated system, 1- [trans-4-（4-diethylaminostyryl）phenyl]imidazole （abbreviated as L）, and its Con complex （COCl2L4）2 （Co2C168H184N24Cl4, Mr = 2799....A novel imidazole derivative with functional group and π-conjugated system, 1- [trans-4-（4-diethylaminostyryl）phenyl]imidazole （abbreviated as L）, and its Con complex （COCl2L4）2 （Co2C168H184N24Cl4, Mr = 2799.05 ） have been synthesized and the crystal structure of the latter was determined by X-ray diffraction. The crystal is of triclinic, space group PI with a = 8.823（3）, b = 18.799（7）, c =23.065（9） A, α = 77.349（6）, β = 83.128（7）, ）, γ= 80.942（3）°, V = 3671.5（12） A^3, Z = 1, Dc = 1.266 g/cm^3,/z = 0.361 mm^-1 F（000） = 1482, the final R = 0.0587 and wR = 0.1284 for 6562 observed reflections with I 〉 2σ（I）. In the molecular structure of （COCl2L4）2, there are two crystallographically unique units. The Co^Ⅱ atoms are six-coordinated by four N atoms from four imidazole ligands （L） and two Cl atoms to form a distorted octahedral geometry. The optical properties of complex （COCl2L4）2 have been experimentally studied.展开更多
The Loess Plateau in China is one of the most eroded areas in the world. Accordingly, vegetation restoration has been implemented in this area over the past two decades to remedy the soil degradation problem. Understa...The Loess Plateau in China is one of the most eroded areas in the world. Accordingly, vegetation restoration has been implemented in this area over the past two decades to remedy the soil degradation problem. Understanding the microbial community structure is essential for the sustainability of ecosystems and for the reclamation of degraded arable land. This study aimed to determine the effect of different vegetation types on microbial processes and community structure in rhizosphere soils in the Loess Plateau. The six vegetation types were as follows：two natural grassland （Artemisia capillaries and Heteropappus altaicus）, two artificial grassland （Astragalus adsurgens and Panicum virgatum）, and two artificial shrubland （Caragana korshinskii and Hippophae rhamnoides） species. The microbial community structure and functional diversity were examined by analyzing the phospholipid fatty acids （PLFAs） and community-level physiological profiles. The results showed that rhizosphere soil sampled from the H. altaicus and A. capillaries plots had the highest values of microbial biomass C, average well color development of carbon resources, Gram-negative （G-） bacterial PLFA, bacterial PLFA, total PLFA, Shannon richness, and Shannon evenness, as well as the lowest metabolic quotient. Soil sampled from the H. rhamnoides plots had the highest metabolic quotient and Gram-positive （G＋） bacterial PLFA, and soil sampled from the A. adsurgens and A. capillaries plots had the highest fungal PLFA and fungal：bacterial PLFA ratio. Correlation analysis indicated a signiifcant positive relationship among the microbial biomass C, G- bacterial PLFA, bacterial PLFA, and total PLFA. In conclusion, plant species under arid climatic conditions signiifcantly affected the microbial community structure in rhizosphere soil. Among the studied plants, natural grassland species generated the most favorable microbial conditions.展开更多
In order to improve the cycle stability of La-Mg-Ni-Co type alloy electrode, rapid quenching technology was employed. The effects of rapid quenching on the microstructure and cycle stability of the alloy were investig...In order to improve the cycle stability of La-Mg-Ni-Co type alloy electrode, rapid quenching technology was employed. The effects of rapid quenching on the microstructure and cycle stability of the alloy were investigated. The obtained results show that the La2Mg(Ni0.85Co0.15)9M0.1 (M=B, Cr) alloy electrodes are composed of (La, Mg)Ni3 phase, LaNi5 phase and a small amount of the LaNi2 phase. A trace of the Ni2B phase exists in the as-cast MB alloy, and the Ni2B phase in the alloy nearly disappears after rapid quenching. Rapid quenching technology can slightly improve the cycling life of the alloy. When the quenching rate increases from 0 m·s-1 (As-cast is defined as quenching rate of 0 m·s-1) to 30 m·s-1, the cycle lives of the MB, MCr alloys enhance from 86 and 87 cycles to 106 and 119 cycles, respectively. On the other hand, the average capacity decay rates of the MB, MCr alloys decrease from 1.7172 and 1.7178 mAh·g-1·cycle-1 to 1.5751 and 1.3060 mAh·g-1·cycle-1 after 86 charge-discharges cycling, respectively.展开更多
AIM To carry out randomized trial for evaluating effects of autologous bone marrow derived stem cell therapy(ABMSCT) through different routes.METHODS Bone marrow aspirate was taken from the iliac crest of patients. Bo...AIM To carry out randomized trial for evaluating effects of autologous bone marrow derived stem cell therapy(ABMSCT) through different routes.METHODS Bone marrow aspirate was taken from the iliac crest of patients. Bone marrow mononuclear cells were separatedand purified using centrifugation. These cells were then infused in a total of 21 patients comprising three groups of 7 patients each. Cells were infused into the superior pancreaticoduodenal artery(Group Ⅰ), splenic artery(Group Ⅱ) and through the peripheral intravenous route(Group Ⅲ). Another group of 7 patients acted as controls and a sham procedure was carried out on them(Group Ⅳ). The cells were labelled with the PET tracer F18-FDG to see their homing and in vivo distribution. Data for clinical outcome was expressed as mean ± SE. All other data was expressed as mean ± SD. Baseline and post treatment data was compared at the end of six months, using paired t-test. Cases and controls data were analyzed using independent t-test. A probability(P) value of < 0.05 was regarded as statistically significant. Measures of clinical outcome were taken as the change or improvement in the following parameters:(1) C-peptide assay;(2) HOMA-IR and HOMA-B;(3) reduction in Insulin dose; subjects who showed reduction of insulin requirement of more than 50% from baseline requirement were regarded as responders; and(4) reduction in HbA 1c. RESULTS All the patients, after being advised for healthy lifestyle changes, were evaluated at periodical intervals and at the end of 6 mo. The changes in body weight, body mass index, waist circumference and percentage of body fat in all groups were not significantly different at the end of this period. The results of intra-group comparison before and after ABMSCT at the end of six months duration was as follows:(1) the area under C-peptide response curve was increased at the end of 6 mo however the difference remained statistically non-significant(P values for fasting C-peptide were 0.973, 0.103, 0.263 and 0.287 respectively and the P values for stimulated C-peptide were 0.989, 0.395, 0.325 and 0.408 respectively for groups Ⅰ?to Ⅳ);(2) the Insulin sensitivity indices of HOMA IR and HOMA B also did not show any significant differences(P values for HOMA IR were 0.368, 0.223, 0.918 and 0.895 respectively and P values for HOMA B were 0.183, 0.664, 0.206 and 0.618 respectively for groups Ⅰto Ⅳ);(3) Group Ⅰshowed a significant reduction in Insulin dose requirement(P < 0.01). Group Ⅱ patients also achieved a significant reduction in Insulin dosages(P = 0.01). The Group Ⅰand Group Ⅱ patients together constituted the targeted group wherein the feeding arteries to pancreas were used for infusing stem cells. Group Ⅲ, which was the intravenous group, showed a non-significant reduction in Insulin dose requirement(P = 0.137). Group Ⅳ patients which comprised the control arm also showed a significant reduction in Insulin dosages at the end of six months(P < 0.05); and(4) there was a non-significant change in the Hb A1 c levels at the end of 6 mo across all groups(P = 0.355, P = 0.351, P = 0.999 and P = 0.408 respectively for groups Ⅰto Ⅳ). CONCLUSION Targeted route showed a significant reduction in Insulin requirement at the end of six months of study period whereas the intravenous group failed to show reduction.展开更多
Tree species diversity and population structure at different community types were described and analyzed for primary and secondary lowland moist deciduous forests in Tripura. Overall 10,957 individual trees belonging ...Tree species diversity and population structure at different community types were described and analyzed for primary and secondary lowland moist deciduous forests in Tripura. Overall 10,957 individual trees belonging to 46 family, 103 genera and 144 species were counted at ≥30 cm DBH （diameter at breast height） using 28 permanent belt transects with a size of 1 ha （10 m × 1000 m）. Four different tree communities were identified. The primary forests was dominated by Shorea robusta （mean density 464.77 trees.ha^-1, 105 species） and Schima wallichii （336.25 trees.ha^-1, 82 species）, while the secondary forests was dominated by Tectona grandis （333.88 trees.ha^-1, 105 species） and Hevea brasiliensis （299.67 trees.ha^-1, 82 species）. Overall mean basal area in this study was 18.01m2.ha^-1; the maximum value was recorded in primary Shorea forest （26.21 m2.ha^-1）. Mean density and diversity indices were differed significantly within four different communities. No significant differences were observed in number of species, genera, family and tree basal cover area. Significant relationships were found between the species richness and different tree population groups across the communities. Results revealed that species diversity and density were increased in those forests due to past disturbances which resulted in slow accumu- lation of native oligarchic small tree species. Seventeen species were recorded with 〈2 individuals of which Saraca asoka （Roxb.） de Wilde and Entada phaseoloides （L.） Men＇. etc. extensively used in local ethnomedicinal formulations. The present S. robusta Gaertn dominated forest was recorded richer （105 species） than other reported studies. Moraceae was found more speciose family instead of Papilionaceae and Euphorbiaceae than other Indian moist deciduous forests. Seasonal phenological gap in such moist deciduous forests influenced the population of Trachypithecus pileatus and capped langur. The analysis of FIV suggested a slow trend of shifting the population of Lamiaceae group by Moraceae species in secondary T. grandis L. dominated community.展开更多
A two-line hybrid rice combination, Liangyoupeijiu, was used to estimate several factors of plant type, and environmental models for these factors at the heading stage were established using the data of eight ecologic...A two-line hybrid rice combination, Liangyoupeijiu, was used to estimate several factors of plant type, and environmental models for these factors at the heading stage were established using the data of eight ecological experimental sites in 2006 and 2007. According to climatic data from 1951 to 2005, the differences in those factors and their effects on plant canopy were analyzed for four rice cropping areas in China, including South China, the middle-lower reaches of the Yangtze River, Sichuan Basin, and river valley in Yunnan, China. The thickness of leaf layer （the distance from pulvinus of the third leaf from the top to the tip of flag leaf） and distribution of leaf area could be used as candidate indices for the plant type of a rice canopy.展开更多
Diabetes mellitus type 2(T2DM)is a global pandemic that will affect 300 million people in the next decade.It has been shown that early and aggressive treatment of T2DM from the onset decreases complications,and the pa...Diabetes mellitus type 2(T2DM)is a global pandemic that will affect 300 million people in the next decade.It has been shown that early and aggressive treatment of T2DM from the onset decreases complications,and the patient’s active role is necessary to achieve better glycemic control.In order to achieve glycemic control targets,an active attitude in patients is needed,and selfmonitoring of blood glucose(SMBG)plays a significant role.Nowadays,SMBG has become an important component of modern therapy for diabetes mellitus,and is even more useful if it is performed in a structured way.SMBG aids physicians and patients to achieve a specific level of glycemic control and to prevent hypoglycemia.In addition,SMBG empowers patients to achieve nutritional and physical activity goals,and helps physicians to optimize the different hypoglycemic therapies as demonstrated in the St Carlos study.This article describes the different ways of using this educational and therapeutic tool from the medical point of view as well as from the patient’s perspective.展开更多
[Zn（L）（CH3OH）3]（H2L = N-（1-phenyl-3-methyl-4-propenylidene-5-pyrazolone）-salicylidene hydrazide） has been synthesized by the reaction of zinc nitrate and ligand H2 L. The complex crystallizes in orthorhombic s...[Zn（L）（CH3OH）3]（H2L = N-（1-phenyl-3-methyl-4-propenylidene-5-pyrazolone）-salicylidene hydrazide） has been synthesized by the reaction of zinc nitrate and ligand H2 L. The complex crystallizes in orthorhombic system, space group Pbca with a = 5.888（15）, b = 14.564（14）, c = 22.20（2） , V = 5137（8） 3, Z = 8 and F（000） = 2184. The ligand serves as a negative bivalent tridentate chelating agent to coordinate with the central zinc（II） atom. DNA-binding was studied by UV-Vis spectral analysis and ethidium bromide（EB） displacement experiments. The results showed that the DNA-binding constant of the complex is 5.1×104 M–1. Antitumor activity of [Zn（L）（CH3OH）3] and the ligand have been investigated by MTT assay, which indicated that the complex has better cytotoxicity to Eca-109 and He La than free ligand.展开更多
Two japonica rice varieties, Longjing 20 （more tillers and curved panicle type, MCP） and Longjing 21 （few tillers and half erect panicle type, FEP）, were used to study the effects of row-spacing on canopy structur...Two japonica rice varieties, Longjing 20 （more tillers and curved panicle type, MCP） and Longjing 21 （few tillers and half erect panicle type, FEP）, were used to study the effects of row-spacing on canopy structure, morphological characteristics and yield. The results showed that the percentage of productive tiller reduced first, and increased afterwards as row-spacing increasing. The relationship between row spacing and the percentage of productive tiller fitted a quadratic regression. The effects of row spacing on leaf area index （LAI） at later tillering stage and the highest stem number per square meter also followed a quadratic regression relationship with increasing first and then reducing. The effects of row-spacing on primary branch were larger than the secondary branch in Longjing 20. However, the trend in Longjing 21 was opposite. The relationship between row spacing and seed setting rate of the secondary branch or panicle was negatively correlated. An extreme significant negative correlation was obtained between seed setting rate of secondary branch in Longjing 20. There was no significant positive correlation between row-spacing and yield in Longjing 20 （R2=0.68）. However, the negative correlation between row-spacing and yield of Longjing 21 was extremely significant （R2=–0.96＊＊）. The canopy structure of MCP was more sensitive to row-spacing. The positive correlation between row spacing and the length of the flag leaf （R2=0.89＊＊）, the width of the flag leaf （R2=0.85＊）, the length of the last internode （R2=0.85＊）, the length of the last 2nd internode （R2=0.96＊＊） or the length of the panicle （R2=0.91＊＊） was significant or extremely significant in Longjing 20, but not in Longjing 21. The wider row-spacing promoted the accumulation of the dry matter of panicle, stem and leaf and the yield formation in MCP. The best row-spacing in Longjing 20 was 30 cm. For Longjing 21, the narrower row-spacing was better. The best row-spacing of it was 21 cm. These results suggested that improved the population environment of MCP or the utilization of the free space in the field of FEP could be reached either by wider row-spacing or narrow row-spacing.展开更多
Different solvothermal reactions of ZnC2O_(4)with oxalic acid(H_(2)ox)and 1,2,4-triazole(Htrz)successfully gave a new quaternary(NJTU-Bai83,NJTU-Bai=Nanjing Tech University Bai's group)and a new quinary(NJTU-Bai84...Different solvothermal reactions of ZnC2O_(4)with oxalic acid(H_(2)ox)and 1,2,4-triazole(Htrz)successfully gave a new quaternary(NJTU-Bai83,NJTU-Bai=Nanjing Tech University Bai's group)and a new quinary(NJTU-Bai84)anionic metal-organic frameworks(MOFs),where NJTU-Bai83=(Me_(2)NH_(2))2[Zn_(3)(trz)_(2)(ox)_(3)]·2H_(2)O and NJTU-Bai84=(Me_(2)NH_(2))[Zn_(3)(trz)_(3)(ox)_(2)]·H_(2)O,respectively.With the[Zn_(2)(ox)4(trz)_(2)]secondary building unit(SBU)in NJTU-Bai83 replaced by the[Zn_(3)(ox)_(2)(trz)_(6)]and planar[Zn(ox)_(2)(trz)_(2)]ones in NJTU-Bai84,2D supramolecular building layers(SBLs)are changed from the A-layer and B-layer to another A-layer,while pillars are transformed from the tetrahedral[Zn(ox)_(2)(trz)_(2)]SBU to the irregular tetrahedral[Zn(ox)_(2)(trz)_(2)]and planar[Zn(ox)_(2)(trz)_(2)]SBUs.Thus,cdq-topological quaternary NJTU-Bai83 is tuned to(4,4,8)-c new topological quinary NJTU-Bai84.Two MOFs were well characterized by powder X-ray diffraction,thermogravimetric analysis,elemental analysis,etc.CCDC:2351819,NJTU-Bai83;2351820,NJTU-Bai84.展开更多
Two new diaryquioxaline derivatives, C21H10N2S3Br2（1） and C21H10Br2 N2OS2（2）,have been successfully synthesized. These two compounds have been determined by single-crystal X-ray diffraction analyses. Compound 1 cr...Two new diaryquioxaline derivatives, C21H10N2S3Br2（1） and C21H10Br2 N2OS2（2）,have been successfully synthesized. These two compounds have been determined by single-crystal X-ray diffraction analyses. Compound 1 crystallizes in monoclinic system, space group P21/n with a = 12.7896（3）, b = 6.0613（2）, c = 26.1153（7） ?, β = 94.1810（10）°, V = 2018.（97） ?3, Z = 4,C21H10N2S3Br2, Mr = 546.32, Dc = 1.797 g/cm3 and F（000） = 1072. The final R = 0.0343 and wR =0.785 for 3585 observed reflections with I > 2σ（I）. Compound 2 crystallizes in monoclinic system,space group P21/n with a = 7.8638（4）, b = 14.3447（7）, c = 17.8936（8） ?, β = 96.6980（10）°, V =2004.69（17） ?3, Z = 4, C21H10Br2 N2OS2, Mr = 530.25, Dc = 1.757 g/cm3 and F（000） = 1040. The final R = 0.0988 and wR = 0.1108 for 4613 observed reflections with I > 2σ（I）. By combination of diarylquinoxaline core and a 1,3-dithiole-2-thione unit, compound 1 is used as "turn on"chemosensors for Hg2+ by making use of the aggregation-induced emission（AIE） feature of diarylquinoxaline core and the specific reaction of 1,3-dithiole-2-thione with Hg2+.展开更多
A 1D supramolecular compound [dmbbbi]（1） and a 2D cobalt coordination polymer [Co（dmbbbi）（ox）] 2（2） [dmbbbi=1,1-（1,4-butanediyl）bis（5,6-dimethylbenzimidazole）,ox=oxalate],C48H52Co2N8O8,were obtained under ...A 1D supramolecular compound [dmbbbi]（1） and a 2D cobalt coordination polymer [Co（dmbbbi）（ox）] 2（2） [dmbbbi=1,1-（1,4-butanediyl）bis（5,6-dimethylbenzimidazole）,ox=oxalate],C48H52Co2N8O8,were obtained under hydrothermal conditions by tuning the molar ratio of the reactants.The crystal structure analysis reveals that in compound 1,the adjacent dmbbbi molecules connect with each other via hydrogen bonds to form a 1D supramolecular chain.In compound 2,two crystallographically independent Co2＋ ions show the same six-coordination mode.Each Co2＋ ion is coordinated by four oxygen atoms from two ox anions and two nitrogen atoms from two cis-dmbbbi ligands.The adjacent Co2＋ ions are bridged by ox anions to generate an infinite 1D zigzag chain,which is extended by pairs of dmbbbi ligands to form a 2D honeycomb-like（6,3） network.Moreover,the thermal stability and the electrochemical property of compound 2 were studied.展开更多
New cadmium and rare earth metal tungstates with the formula Cd0.25RE0.50 0.25WO4 （RE=Nd, Sin, Eu, Gd, D-statistical distrib- uted vacancies in cation sublattice） were synthesized by the solid-state reaction between...New cadmium and rare earth metal tungstates with the formula Cd0.25RE0.50 0.25WO4 （RE=Nd, Sin, Eu, Gd, D-statistical distrib- uted vacancies in cation sublattice） were synthesized by the solid-state reaction between CdWO4 and corresponding RE2W209. The obtained phases crystallize in the scheelite type structure. The Cd0.25RE0.5 0.25WO4 compounds were characterized by X-ray diffractometer （XRD）, （DTA-TG）, infrared （IR） and EPR methods.展开更多
A novel and efficient Ir-catalyzed 1,4-and 1,2-addition of diphenylphosphine oxide to quinolines was developed to obtain various 1,2,3,4-tetrahydroquinoline-2,4-diyl（bisdiphenylphosphine oxide） derivatives. The stru...A novel and efficient Ir-catalyzed 1,4-and 1,2-addition of diphenylphosphine oxide to quinolines was developed to obtain various 1,2,3,4-tetrahydroquinoline-2,4-diyl（bisdiphenylphosphine oxide） derivatives. The structures of these derivatives were characterized by H-RMS and NMR analysis. X-ray crystallography showed that 3 a is in a monoclinic system, space group of P21/c with a = 13.0464（16）, b = 12.6244（16）, c = 20.210（3） ?, β = 105.215（2）o, V =3211.9（7） ?3, Z = 4, F（000） = 1352, μ = 0.42 mm–1, S = 1.07, the final R = 0.059 and wR = 0.195.The in vitro antitumor activities of target compounds were evaluated by MTT assay against human cancer K562, HL-60, HeLa and BGC-823. The target compounds demonstrated weak or moderate antitumor activity against these cell lines.展开更多
Two new a-aminophosphonate derivatives containing thieno[2,3-d]pyrimidine, diethyl（（（6-ethyl-2-methyl-4-oxothieno[2,3-d]pyrimidin-3 （4H）-yl）amino）（4-methoxyphenyl）methyl） phosphonate （1） and diethyl（（4-b...Two new a-aminophosphonate derivatives containing thieno[2,3-d]pyrimidine, diethyl（（（6-ethyl-2-methyl-4-oxothieno[2,3-d]pyrimidin-3 （4H）-yl）amino）（4-methoxyphenyl）methyl） phosphonate （1） and diethyl（（4-bromophenyl）（（6-ethyl-2-methyl-4-oxothieno[2,3-d]pyrimidin-3 （4//）-yl）amino）methyl）phosphonate （2）, have been synthesized by a facial phosphorylated reaction, and their structures were characterized by NMR, IR, HRMS and X-ray single-crystal diffraction. Compound 1 （C21H28N3O5PS, Mr = 465.49） belongs to the orthorhombic system, space group P212121, with a = 10.83653（16）, b = 12.04906（19）, c = 18.0061（3） A, V= 2351.06（6） A3, Z= 4, Dc= 1.315 g/cm3, p = 2.177 mm-1, F（000） = 984.0, the final R = 0.0389 and wR = 0.0985 for all data. Compound 2 （C20H25BrN304PS, Mr = 514.37） belongs to the orthorhombic system, space group P212121, with a = 10.9187（5）, b = 11.9522（4）, c = 17.7667（7） A, V= 2318.60（16） A3, Z = 4, Dc= 1.474 g/cm3,μ = 4.175 mm^-1, F（000） = 1056.0, the final R = 0.0367 and wR = 0.0946 for all data.展开更多
文摘Aim: This paper aims to evaluate disparities of type 2 diabetes structured health education programmes that is utilised within the communities. Design: systematic review, (a type of secondary research design) aiming to summarize the results of prior primary research studies on available evidence Community type 2 diabetes structured education (CT2DSHE). Methods: Research question: Type 2 diabetic structured health education within a community how effective is it? Qualitative Systematic review, defined as a way to get reliable and objective picture of current available evidence on the specific topic—(CT2DSHE), (Denscombe, 2021) through reflexivity synthesis of available data as an example. This is valuable in time constraints such as project assignments that must be met within specific time and also to bring together available evidence together [1]. Results: This review has shown that CT2DSHE is effective with seven out of the eleven authors supporting, three authors against and one was neutral, further showed that knowledge and skills acquired can last longer with patient activation improved among T2DM patients ideal for sustaining their self-management of T2DM. Conclusion: This research provides suggestive answers to the research question: “Type 2 diabetic structured health education within a community how effective is it?”, This has demonstrated CT2DSHE effectiveness in knowledge acquisition and improving T2DM awareness among T2DM patients, whilst evidencing long effects beyond the study times of 3 - 9 months period in relation to patient activation. Also Identified diabetes education self-management on newly diagnosed (DESMOND) patient as CT2DSHE program for recommendation. Patient or Public Contribution: This work aspires to contribute to CT2DSHE in these areas;Influencing policy decision-making for community diabetes care within the UK and world at large., Contributing to already vast knowledge on diabetes self-management and reasons why?, Influencing educators on how CT2DSHEP are designed, delivered by putting the patient at the Centre and bringing different perspectives on CT2DSHEP in one place that is serving users time of having to consult several resources especially busy clinicians [2] [3].
基金This work was supported by the National Natural Science Foundation of China (No. 30672516)
文摘A genistein derivative, 5-hydroxy-3-（4-hydroxyphenyl）-7-（2-（piperidin- 1-yl）ethoxy）- 4H-chromen-4-one 3, was designed, prepared and structurally characterized by single-crystal X-ray diffraction. X-ray structure analysis reveals that 3 crystallizes in the orthorhombic system, space group Pbca, with a = 16.238（3）, b = 10.308（2）, c = 22.987（5）A, V = 3847.6（13）A3, Z = 8,μ= 0.093 mm^-1, Dc = 1.317 g/cm^3, F（000） = 1616, R = 0.0789 and wR = 0.1554 for 1463 observed reflections with I 〉 2σ（I）.
文摘A new hydrogen bonded Cobalt(II) Schiff base complex,?N’-(pyridine-4-carboxaldehyde) isonicotinoylhydrazone Cobalt(II), has been synthesized from isoniazid and pyridine-4-carboxaldehyde and characterized by IR spectroscopy, 1H-NMR, elemental analysis, TGA and single crystal X-ray structure determination. X-ray crystal structure analysis shows an octahedral complex with a metal centre coordinated to two ligand molecules through the pyridine nitrogen atoms and four water molecules and containing two nitrate groups as counter ions. The complex crystallizes in the monoclinic crystal system and P2(1)/n space group. The unit cell dimensions are: a = 7.2108(4) Å, b = 16.6020(9) Å, c = 13.0389(6) Å,α = 90°, β = 103.972(4)°, γ = 90°. The molecule is symmetrical about the cobalt centre as observed from the 1H-NMR and 13C-NMR and confirmed by the single crystal X-ray structure of the complex. Thermogravimetric analysis shows two steps decomposition of the complex to leave a metal oxide residue. The title compound is expected to be biologically active as one of the precursors (isoniazid) is a therapeutic agent with well-established clinical applications.
基金Supported by Guangxi Provincial Department of Education(No.YB2014333)the Scientific research and technological development project of Guilin(No.20110330)+2 种基金the Project of Key Laboratory for the Chemistry and Molecular Engineering of Medicinal Resources(Guangxi Normal University)Ministry of Education of China(CMEMR2011-13)Key Subjects of Universities in Guangxi Province Applied Chemistry(2007<20>)
文摘A new chain-like coordination polymer, namely, [CuL]n （1, Na2L = 2-[（2-hydroxy- benzylidene）-amino]-benzenesulfonic acid sodium salt）, has been synthesized and characterized by single-crystal X-ray diffraction, IR spectroscopy and elemental analysis. Complex 1 crystallizes in monoclinic system, space group P21/c with a = 9.2296（16）, b = 10.4754（18）, c = 12.200（2） A, β = 102.392（2）°, V = 1152.0（3）A3, CI3H9CuNOaN, Mr = 338.83, Dc = 1.953 g/cm3, Z = 4, F（000） = 684, p = 2.089 mm-1, the final R = 0.0376 and wR = 0.0956. X-ray diffraction analyses indicate that 1 displays a square-pyramidal metal center with NO4 donor sets. The sulfonate-derived Schiff base serves as a common N,O,O＇-tridentate and a unique O-bridged ligand connecting the metals. Dinuclear copper complexes serve as secondary building blocks （SBUs） to construct an unusual 2D coordination network. In the crystal, the components form a stable 3D supramolecular architecture by C-H...O interactions and to-stacking
基金Supported by National Key R&D program of China(Grant No.2017YFB1301800)National Natural Science Foundation of China(Grant No.51622508)National Defense Basic Scientific Research program of China(Grant No.JCKY2017203B066)
文摘Direct kinematics with analytic solutions is critical to the real-time control of parallel mechanisms.Therefore,the type synthesis of a mechanism having explicit form of forward kinematics has become a topic of interest.Based on this purpose,this paper deals with the type synthesis of 1T2R parallel mechanisms by investigating the topological structure coupling-reducing of the 3UPS&UP parallel mechanism.With the aid of the theory of mechanism topology,the analysis of the topological characteristics of the 3UPS&UP parallel mechanism is presented,which shows that there are highly coupled motions and constraints amongst the limbs of the mechanism.Three methods for structure coupling-reducing of the 3UPS&UP parallel mechanism are proposed,resulting in eight new types of 1T2R parallel mechanisms with one or zero coupling degree.One obtained parallel mechanism is taken as an example to demonstrate that a mechanism with zero coupling degree has an explicit form for forward kinematics.The process of type synthesis is in the order of permutation and combination;therefore,there are no omissions.This method is also appli cable to other configurations,and novel topological structures having simple forward kinematics can be obtained from an original mechanism via this method.
基金This work was supported by the National Natural Science Foundation of China (50532030, 50335050, and 50325311) and Education Committee of Anhui Province (2006KJ158B)
文摘A novel imidazole derivative with functional group and π-conjugated system, 1- [trans-4-（4-diethylaminostyryl）phenyl]imidazole （abbreviated as L）, and its Con complex （COCl2L4）2 （Co2C168H184N24Cl4, Mr = 2799.05 ） have been synthesized and the crystal structure of the latter was determined by X-ray diffraction. The crystal is of triclinic, space group PI with a = 8.823（3）, b = 18.799（7）, c =23.065（9） A, α = 77.349（6）, β = 83.128（7）, ）, γ= 80.942（3）°, V = 3671.5（12） A^3, Z = 1, Dc = 1.266 g/cm^3,/z = 0.361 mm^-1 F（000） = 1482, the final R = 0.0587 and wR = 0.1284 for 6562 observed reflections with I 〉 2σ（I）. In the molecular structure of （COCl2L4）2, there are two crystallographically unique units. The Co^Ⅱ atoms are six-coordinated by four N atoms from four imidazole ligands （L） and two Cl atoms to form a distorted octahedral geometry. The optical properties of complex （COCl2L4）2 have been experimentally studied.
基金supported by the Strategic Technology Project of Chinese Academy of Sciences(XDA05060300)the Science and Technology Research and Development Program of Shaanxi ProvinceChina(2011KJXX63)
文摘The Loess Plateau in China is one of the most eroded areas in the world. Accordingly, vegetation restoration has been implemented in this area over the past two decades to remedy the soil degradation problem. Understanding the microbial community structure is essential for the sustainability of ecosystems and for the reclamation of degraded arable land. This study aimed to determine the effect of different vegetation types on microbial processes and community structure in rhizosphere soils in the Loess Plateau. The six vegetation types were as follows：two natural grassland （Artemisia capillaries and Heteropappus altaicus）, two artificial grassland （Astragalus adsurgens and Panicum virgatum）, and two artificial shrubland （Caragana korshinskii and Hippophae rhamnoides） species. The microbial community structure and functional diversity were examined by analyzing the phospholipid fatty acids （PLFAs） and community-level physiological profiles. The results showed that rhizosphere soil sampled from the H. altaicus and A. capillaries plots had the highest values of microbial biomass C, average well color development of carbon resources, Gram-negative （G-） bacterial PLFA, bacterial PLFA, total PLFA, Shannon richness, and Shannon evenness, as well as the lowest metabolic quotient. Soil sampled from the H. rhamnoides plots had the highest metabolic quotient and Gram-positive （G＋） bacterial PLFA, and soil sampled from the A. adsurgens and A. capillaries plots had the highest fungal PLFA and fungal：bacterial PLFA ratio. Correlation analysis indicated a signiifcant positive relationship among the microbial biomass C, G- bacterial PLFA, bacterial PLFA, and total PLFA. In conclusion, plant species under arid climatic conditions signiifcantly affected the microbial community structure in rhizosphere soil. Among the studied plants, natural grassland species generated the most favorable microbial conditions.
基金This work was financially supported by National Natural Science Foundations of China (No.50131040)Key Technologies R & D Program of Inner Mongolia (No.20050205)College Scientific Research Project of Inner Mongolia (No.NJ05064).
文摘In order to improve the cycle stability of La-Mg-Ni-Co type alloy electrode, rapid quenching technology was employed. The effects of rapid quenching on the microstructure and cycle stability of the alloy were investigated. The obtained results show that the La2Mg(Ni0.85Co0.15)9M0.1 (M=B, Cr) alloy electrodes are composed of (La, Mg)Ni3 phase, LaNi5 phase and a small amount of the LaNi2 phase. A trace of the Ni2B phase exists in the as-cast MB alloy, and the Ni2B phase in the alloy nearly disappears after rapid quenching. Rapid quenching technology can slightly improve the cycling life of the alloy. When the quenching rate increases from 0 m·s-1 (As-cast is defined as quenching rate of 0 m·s-1) to 30 m·s-1, the cycle lives of the MB, MCr alloys enhance from 86 and 87 cycles to 106 and 119 cycles, respectively. On the other hand, the average capacity decay rates of the MB, MCr alloys decrease from 1.7172 and 1.7178 mAh·g-1·cycle-1 to 1.5751 and 1.3060 mAh·g-1·cycle-1 after 86 charge-discharges cycling, respectively.
文摘AIM To carry out randomized trial for evaluating effects of autologous bone marrow derived stem cell therapy(ABMSCT) through different routes.METHODS Bone marrow aspirate was taken from the iliac crest of patients. Bone marrow mononuclear cells were separatedand purified using centrifugation. These cells were then infused in a total of 21 patients comprising three groups of 7 patients each. Cells were infused into the superior pancreaticoduodenal artery(Group Ⅰ), splenic artery(Group Ⅱ) and through the peripheral intravenous route(Group Ⅲ). Another group of 7 patients acted as controls and a sham procedure was carried out on them(Group Ⅳ). The cells were labelled with the PET tracer F18-FDG to see their homing and in vivo distribution. Data for clinical outcome was expressed as mean ± SE. All other data was expressed as mean ± SD. Baseline and post treatment data was compared at the end of six months, using paired t-test. Cases and controls data were analyzed using independent t-test. A probability(P) value of < 0.05 was regarded as statistically significant. Measures of clinical outcome were taken as the change or improvement in the following parameters:(1) C-peptide assay;(2) HOMA-IR and HOMA-B;(3) reduction in Insulin dose; subjects who showed reduction of insulin requirement of more than 50% from baseline requirement were regarded as responders; and(4) reduction in HbA 1c. RESULTS All the patients, after being advised for healthy lifestyle changes, were evaluated at periodical intervals and at the end of 6 mo. The changes in body weight, body mass index, waist circumference and percentage of body fat in all groups were not significantly different at the end of this period. The results of intra-group comparison before and after ABMSCT at the end of six months duration was as follows:(1) the area under C-peptide response curve was increased at the end of 6 mo however the difference remained statistically non-significant(P values for fasting C-peptide were 0.973, 0.103, 0.263 and 0.287 respectively and the P values for stimulated C-peptide were 0.989, 0.395, 0.325 and 0.408 respectively for groups Ⅰ?to Ⅳ);(2) the Insulin sensitivity indices of HOMA IR and HOMA B also did not show any significant differences(P values for HOMA IR were 0.368, 0.223, 0.918 and 0.895 respectively and P values for HOMA B were 0.183, 0.664, 0.206 and 0.618 respectively for groups Ⅰto Ⅳ);(3) Group Ⅰshowed a significant reduction in Insulin dose requirement(P < 0.01). Group Ⅱ patients also achieved a significant reduction in Insulin dosages(P = 0.01). The Group Ⅰand Group Ⅱ patients together constituted the targeted group wherein the feeding arteries to pancreas were used for infusing stem cells. Group Ⅲ, which was the intravenous group, showed a non-significant reduction in Insulin dose requirement(P = 0.137). Group Ⅳ patients which comprised the control arm also showed a significant reduction in Insulin dosages at the end of six months(P < 0.05); and(4) there was a non-significant change in the Hb A1 c levels at the end of 6 mo across all groups(P = 0.355, P = 0.351, P = 0.999 and P = 0.408 respectively for groups Ⅰto Ⅳ). CONCLUSION Targeted route showed a significant reduction in Insulin requirement at the end of six months of study period whereas the intravenous group failed to show reduction.
基金supported by DBT Network Project (BT/PR7928/NDB/52/9/2006)Department of Biotechnology(DBT),Govt. of India
文摘Tree species diversity and population structure at different community types were described and analyzed for primary and secondary lowland moist deciduous forests in Tripura. Overall 10,957 individual trees belonging to 46 family, 103 genera and 144 species were counted at ≥30 cm DBH （diameter at breast height） using 28 permanent belt transects with a size of 1 ha （10 m × 1000 m）. Four different tree communities were identified. The primary forests was dominated by Shorea robusta （mean density 464.77 trees.ha^-1, 105 species） and Schima wallichii （336.25 trees.ha^-1, 82 species）, while the secondary forests was dominated by Tectona grandis （333.88 trees.ha^-1, 105 species） and Hevea brasiliensis （299.67 trees.ha^-1, 82 species）. Overall mean basal area in this study was 18.01m2.ha^-1; the maximum value was recorded in primary Shorea forest （26.21 m2.ha^-1）. Mean density and diversity indices were differed significantly within four different communities. No significant differences were observed in number of species, genera, family and tree basal cover area. Significant relationships were found between the species richness and different tree population groups across the communities. Results revealed that species diversity and density were increased in those forests due to past disturbances which resulted in slow accumu- lation of native oligarchic small tree species. Seventeen species were recorded with 〈2 individuals of which Saraca asoka （Roxb.） de Wilde and Entada phaseoloides （L.） Men＇. etc. extensively used in local ethnomedicinal formulations. The present S. robusta Gaertn dominated forest was recorded richer （105 species） than other reported studies. Moraceae was found more speciose family instead of Papilionaceae and Euphorbiaceae than other Indian moist deciduous forests. Seasonal phenological gap in such moist deciduous forests influenced the population of Trachypithecus pileatus and capped langur. The analysis of FIV suggested a slow trend of shifting the population of Lamiaceae group by Moraceae species in secondary T. grandis L. dominated community.
基金supported by the National Natural Science Foundation of China (Grant No. 30370830)
文摘A two-line hybrid rice combination, Liangyoupeijiu, was used to estimate several factors of plant type, and environmental models for these factors at the heading stage were established using the data of eight ecological experimental sites in 2006 and 2007. According to climatic data from 1951 to 2005, the differences in those factors and their effects on plant canopy were analyzed for four rice cropping areas in China, including South China, the middle-lower reaches of the Yangtze River, Sichuan Basin, and river valley in Yunnan, China. The thickness of leaf layer （the distance from pulvinus of the third leaf from the top to the tip of flag leaf） and distribution of leaf area could be used as candidate indices for the plant type of a rice canopy.
文摘Diabetes mellitus type 2(T2DM)is a global pandemic that will affect 300 million people in the next decade.It has been shown that early and aggressive treatment of T2DM from the onset decreases complications,and the patient’s active role is necessary to achieve better glycemic control.In order to achieve glycemic control targets,an active attitude in patients is needed,and selfmonitoring of blood glucose(SMBG)plays a significant role.Nowadays,SMBG has become an important component of modern therapy for diabetes mellitus,and is even more useful if it is performed in a structured way.SMBG aids physicians and patients to achieve a specific level of glycemic control and to prevent hypoglycemia.In addition,SMBG empowers patients to achieve nutritional and physical activity goals,and helps physicians to optimize the different hypoglycemic therapies as demonstrated in the St Carlos study.This article describes the different ways of using this educational and therapeutic tool from the medical point of view as well as from the patient’s perspective.
基金Supported by the National Science Foundation of China(No.21161019,21301146)Natural Science Fund for Distinguished Young Scholars of Xinjiang Uygur Autonomous(No.2013711008)Technological Innovation Youth Training Project of Xinjiang Autonomous(No.2013721017)
文摘[Zn（L）（CH3OH）3]（H2L = N-（1-phenyl-3-methyl-4-propenylidene-5-pyrazolone）-salicylidene hydrazide） has been synthesized by the reaction of zinc nitrate and ligand H2 L. The complex crystallizes in orthorhombic system, space group Pbca with a = 5.888（15）, b = 14.564（14）, c = 22.20（2） , V = 5137（8） 3, Z = 8 and F（000） = 2184. The ligand serves as a negative bivalent tridentate chelating agent to coordinate with the central zinc（II） atom. DNA-binding was studied by UV-Vis spectral analysis and ethidium bromide（EB） displacement experiments. The results showed that the DNA-binding constant of the complex is 5.1×104 M–1. Antitumor activity of [Zn（L）（CH3OH）3] and the ligand have been investigated by MTT assay, which indicated that the complex has better cytotoxicity to Eca-109 and He La than free ligand.
基金Supported by the National Key Technology R&D Program (2007BAD65B01-4)Science and Technology Development Plan of Heilongjiang Province in China (GB06B104-1-5)Key Technology R&D Program of Heilongjiang Province in China (GA09B102-3)
文摘Two japonica rice varieties, Longjing 20 （more tillers and curved panicle type, MCP） and Longjing 21 （few tillers and half erect panicle type, FEP）, were used to study the effects of row-spacing on canopy structure, morphological characteristics and yield. The results showed that the percentage of productive tiller reduced first, and increased afterwards as row-spacing increasing. The relationship between row spacing and the percentage of productive tiller fitted a quadratic regression. The effects of row spacing on leaf area index （LAI） at later tillering stage and the highest stem number per square meter also followed a quadratic regression relationship with increasing first and then reducing. The effects of row-spacing on primary branch were larger than the secondary branch in Longjing 20. However, the trend in Longjing 21 was opposite. The relationship between row spacing and seed setting rate of the secondary branch or panicle was negatively correlated. An extreme significant negative correlation was obtained between seed setting rate of secondary branch in Longjing 20. There was no significant positive correlation between row-spacing and yield in Longjing 20 （R2=0.68）. However, the negative correlation between row-spacing and yield of Longjing 21 was extremely significant （R2=–0.96＊＊）. The canopy structure of MCP was more sensitive to row-spacing. The positive correlation between row spacing and the length of the flag leaf （R2=0.89＊＊）, the width of the flag leaf （R2=0.85＊）, the length of the last internode （R2=0.85＊）, the length of the last 2nd internode （R2=0.96＊＊） or the length of the panicle （R2=0.91＊＊） was significant or extremely significant in Longjing 20, but not in Longjing 21. The wider row-spacing promoted the accumulation of the dry matter of panicle, stem and leaf and the yield formation in MCP. The best row-spacing in Longjing 20 was 30 cm. For Longjing 21, the narrower row-spacing was better. The best row-spacing of it was 21 cm. These results suggested that improved the population environment of MCP or the utilization of the free space in the field of FEP could be reached either by wider row-spacing or narrow row-spacing.
文摘Different solvothermal reactions of ZnC2O_(4)with oxalic acid(H_(2)ox)and 1,2,4-triazole(Htrz)successfully gave a new quaternary(NJTU-Bai83,NJTU-Bai=Nanjing Tech University Bai's group)and a new quinary(NJTU-Bai84)anionic metal-organic frameworks(MOFs),where NJTU-Bai83=(Me_(2)NH_(2))2[Zn_(3)(trz)_(2)(ox)_(3)]·2H_(2)O and NJTU-Bai84=(Me_(2)NH_(2))[Zn_(3)(trz)_(3)(ox)_(2)]·H_(2)O,respectively.With the[Zn_(2)(ox)4(trz)_(2)]secondary building unit(SBU)in NJTU-Bai83 replaced by the[Zn_(3)(ox)_(2)(trz)_(6)]and planar[Zn(ox)_(2)(trz)_(2)]ones in NJTU-Bai84,2D supramolecular building layers(SBLs)are changed from the A-layer and B-layer to another A-layer,while pillars are transformed from the tetrahedral[Zn(ox)_(2)(trz)_(2)]SBU to the irregular tetrahedral[Zn(ox)_(2)(trz)_(2)]and planar[Zn(ox)_(2)(trz)_(2)]SBUs.Thus,cdq-topological quaternary NJTU-Bai83 is tuned to(4,4,8)-c new topological quinary NJTU-Bai84.Two MOFs were well characterized by powder X-ray diffraction,thermogravimetric analysis,elemental analysis,etc.CCDC:2351819,NJTU-Bai83;2351820,NJTU-Bai84.
基金supported by the National Natural Science Foundation of China(21372136)
文摘Two new diaryquioxaline derivatives, C21H10N2S3Br2（1） and C21H10Br2 N2OS2（2）,have been successfully synthesized. These two compounds have been determined by single-crystal X-ray diffraction analyses. Compound 1 crystallizes in monoclinic system, space group P21/n with a = 12.7896（3）, b = 6.0613（2）, c = 26.1153（7） ?, β = 94.1810（10）°, V = 2018.（97） ?3, Z = 4,C21H10N2S3Br2, Mr = 546.32, Dc = 1.797 g/cm3 and F（000） = 1072. The final R = 0.0343 and wR =0.785 for 3585 observed reflections with I > 2σ（I）. Compound 2 crystallizes in monoclinic system,space group P21/n with a = 7.8638（4）, b = 14.3447（7）, c = 17.8936（8） ?, β = 96.6980（10）°, V =2004.69（17） ?3, Z = 4, C21H10Br2 N2OS2, Mr = 530.25, Dc = 1.757 g/cm3 and F（000） = 1040. The final R = 0.0988 and wR = 0.1108 for 4613 observed reflections with I > 2σ（I）. By combination of diarylquinoxaline core and a 1,3-dithiole-2-thione unit, compound 1 is used as "turn on"chemosensors for Hg2+ by making use of the aggregation-induced emission（AIE） feature of diarylquinoxaline core and the specific reaction of 1,3-dithiole-2-thione with Hg2+.
基金Supported by the National Natural Science Foundation of China(No.21171025)the Natural Science Foundation of Liaoning Province,China(Nos.201102003 and 2009402007)
文摘A 1D supramolecular compound [dmbbbi]（1） and a 2D cobalt coordination polymer [Co（dmbbbi）（ox）] 2（2） [dmbbbi=1,1-（1,4-butanediyl）bis（5,6-dimethylbenzimidazole）,ox=oxalate],C48H52Co2N8O8,were obtained under hydrothermal conditions by tuning the molar ratio of the reactants.The crystal structure analysis reveals that in compound 1,the adjacent dmbbbi molecules connect with each other via hydrogen bonds to form a 1D supramolecular chain.In compound 2,two crystallographically independent Co2＋ ions show the same six-coordination mode.Each Co2＋ ion is coordinated by four oxygen atoms from two ox anions and two nitrogen atoms from two cis-dmbbbi ligands.The adjacent Co2＋ ions are bridged by ox anions to generate an infinite 1D zigzag chain,which is extended by pairs of dmbbbi ligands to form a 2D honeycomb-like（6,3） network.Moreover,the thermal stability and the electrochemical property of compound 2 were studied.
文摘New cadmium and rare earth metal tungstates with the formula Cd0.25RE0.50 0.25WO4 （RE=Nd, Sin, Eu, Gd, D-statistical distrib- uted vacancies in cation sublattice） were synthesized by the solid-state reaction between CdWO4 and corresponding RE2W209. The obtained phases crystallize in the scheelite type structure. The Cd0.25RE0.5 0.25WO4 compounds were characterized by X-ray diffractometer （XRD）, （DTA-TG）, infrared （IR） and EPR methods.
基金Supported by the foundation of the Department of Education of Guangdong Province(2016KTSCX144,2017KZDXM085)Natural Science Foundation of Hunan Province(No.2018JJ3196)the High-level Scientific Research Foundation for the introduction of talent(AL2018008)
文摘A novel and efficient Ir-catalyzed 1,4-and 1,2-addition of diphenylphosphine oxide to quinolines was developed to obtain various 1,2,3,4-tetrahydroquinoline-2,4-diyl（bisdiphenylphosphine oxide） derivatives. The structures of these derivatives were characterized by H-RMS and NMR analysis. X-ray crystallography showed that 3 a is in a monoclinic system, space group of P21/c with a = 13.0464（16）, b = 12.6244（16）, c = 20.210（3） ?, β = 105.215（2）o, V =3211.9（7） ?3, Z = 4, F（000） = 1352, μ = 0.42 mm–1, S = 1.07, the final R = 0.059 and wR = 0.195.The in vitro antitumor activities of target compounds were evaluated by MTT assay against human cancer K562, HL-60, HeLa and BGC-823. The target compounds demonstrated weak or moderate antitumor activity against these cell lines.
基金supported by the National Natural Science Foundation of China(Nos.21105091 and 21171149)
文摘Two new a-aminophosphonate derivatives containing thieno[2,3-d]pyrimidine, diethyl（（（6-ethyl-2-methyl-4-oxothieno[2,3-d]pyrimidin-3 （4H）-yl）amino）（4-methoxyphenyl）methyl） phosphonate （1） and diethyl（（4-bromophenyl）（（6-ethyl-2-methyl-4-oxothieno[2,3-d]pyrimidin-3 （4//）-yl）amino）methyl）phosphonate （2）, have been synthesized by a facial phosphorylated reaction, and their structures were characterized by NMR, IR, HRMS and X-ray single-crystal diffraction. Compound 1 （C21H28N3O5PS, Mr = 465.49） belongs to the orthorhombic system, space group P212121, with a = 10.83653（16）, b = 12.04906（19）, c = 18.0061（3） A, V= 2351.06（6） A3, Z= 4, Dc= 1.315 g/cm3, p = 2.177 mm-1, F（000） = 984.0, the final R = 0.0389 and wR = 0.0985 for all data. Compound 2 （C20H25BrN304PS, Mr = 514.37） belongs to the orthorhombic system, space group P212121, with a = 10.9187（5）, b = 11.9522（4）, c = 17.7667（7） A, V= 2318.60（16） A3, Z = 4, Dc= 1.474 g/cm3,μ = 4.175 mm^-1, F（000） = 1056.0, the final R = 0.0367 and wR = 0.0946 for all data.
