Cardiovascular magnetic resonance (CMR) has become a reference standard for the measure-ment of cardiac volumes, function, and mass. This study aims to reconstruct three dimen-sional modeling of the left ventricle (LV...Cardiovascular magnetic resonance (CMR) has become a reference standard for the measure-ment of cardiac volumes, function, and mass. This study aims to reconstruct three dimen-sional modeling of the left ventricle (LV) in pa-tients with heart failure (HF) using CMRtools and thereby derive the LV functional indices. CMR images were acquired in 41 subjects (6 females) with heart failure (HF) and 12 normal controls (4 females). Five comparisons were made (i) nor-mal and dilated heart failure subjects, (ii) male and female normal heart, (iii) male and female dilated heart, (iv) male normal and dilated heart failure and (v) female normal and dilated heart failure. In HF, a significant higher values of EDV (320 刡 79 vs. 126 刡 22 ml, P<0.0001), ESV (255 刡 68 vs. 54 刡 12 ml, P<0.00001) and lower values of EF (20 刡 7 vs. 58 刡 5 %) were found compared that of normal control. There were significant difference on LV EDV and ESV between sex in both normal and HF subjects.展开更多
目的应用超声心动图组织多普勒技术评价右室心尖部起搏对左室收缩同步性及心脏功能的影响,探讨起搏诱发的心室不同步收缩对于心脏功能的影响机制。方法65例置入双腔起搏器的病窦综合征患者分别在心室节律全部为起搏节律或室上性节律状...目的应用超声心动图组织多普勒技术评价右室心尖部起搏对左室收缩同步性及心脏功能的影响,探讨起搏诱发的心室不同步收缩对于心脏功能的影响机制。方法65例置入双腔起搏器的病窦综合征患者分别在心室节律全部为起搏节律或室上性节律状态下行常规及组织多普勒超声心动图检查,测量左室收缩功能及收缩同步性指标。结果右室完全起搏模式下左室收缩功能下降(射血分数:0.58±0.07 vs 0.61±0.01,P<0.001),左室6节段收缩期平均速度下降(4.0±1.5cm/s vs 4.7±1.6cm/s,P<0.001),心室收缩同步性下降(12节段达峰时间标准差:37.5±12.5ms vs 23.7±10.2ms,P<0.001),心室同步性恶化程度与收缩功能恶化中度相关(r=0.37,P<0.05)。结论右室心尖部起搏可致左室收缩不同步及左室功能降低。展开更多
文摘Cardiovascular magnetic resonance (CMR) has become a reference standard for the measure-ment of cardiac volumes, function, and mass. This study aims to reconstruct three dimen-sional modeling of the left ventricle (LV) in pa-tients with heart failure (HF) using CMRtools and thereby derive the LV functional indices. CMR images were acquired in 41 subjects (6 females) with heart failure (HF) and 12 normal controls (4 females). Five comparisons were made (i) nor-mal and dilated heart failure subjects, (ii) male and female normal heart, (iii) male and female dilated heart, (iv) male normal and dilated heart failure and (v) female normal and dilated heart failure. In HF, a significant higher values of EDV (320 刡 79 vs. 126 刡 22 ml, P&amp;amp;amp;amp;lt;0.0001), ESV (255 刡 68 vs. 54 刡 12 ml, P&amp;amp;amp;amp;lt;0.00001) and lower values of EF (20 刡 7 vs. 58 刡 5 %) were found compared that of normal control. There were significant difference on LV EDV and ESV between sex in both normal and HF subjects.
文摘目的应用超声心动图组织多普勒技术评价右室心尖部起搏对左室收缩同步性及心脏功能的影响,探讨起搏诱发的心室不同步收缩对于心脏功能的影响机制。方法65例置入双腔起搏器的病窦综合征患者分别在心室节律全部为起搏节律或室上性节律状态下行常规及组织多普勒超声心动图检查,测量左室收缩功能及收缩同步性指标。结果右室完全起搏模式下左室收缩功能下降(射血分数:0.58±0.07 vs 0.61±0.01,P<0.001),左室6节段收缩期平均速度下降(4.0±1.5cm/s vs 4.7±1.6cm/s,P<0.001),心室收缩同步性下降(12节段达峰时间标准差:37.5±12.5ms vs 23.7±10.2ms,P<0.001),心室同步性恶化程度与收缩功能恶化中度相关(r=0.37,P<0.05)。结论右室心尖部起搏可致左室收缩不同步及左室功能降低。
文摘目的探讨三维斑点追踪成像(3-dimensional speckle tracking imaging,3D-STI)技术评价妊娠高血压综合征(pregnancy-induced hypertension syndrome,PIHS)患者产前和产后左心室收缩功能的临床价值。方法采用3D-STI测量32例待产的PIHS孕妇(PIHS产前组)、30例产后3个月复查的PIHS产妇(PIHS产后组)及40例待产的正常孕妇(正常对照组)的左心室整体纵向收缩期峰值应变(left ventricle global longitudinal strain,LVGLS)、左心室整体径向收缩期峰值应变(left ventricle global radial strain,LVGRS)、左心室整体圆周收缩期峰值应变(left ventricle global circumferential strain,LVGCS)、左心室整体面积收缩期峰值应变(left ventricular global area peak systolic strain,LVGAS)值,并进行比较。结果与正常对照组比较,PIHS产前组LVGLS值降低(P<0.05),LVGRS、LVGCS、LVGAS值无明显变化(P>0.05);PIHS产后组LVGLS、LVGRS、LVGCS、LVGAS值无明显变化(P>0.05)。与PIHS产前组比较,PIHS产后组LVGLS值升高(P<0.05),LVGRS、LVGCS、LVGAS值无明显变化(P>0.05)。结论 3D-STI技术通过评估PIH患者产前及产后3个月左心室的三维整体应变,可反映PIH患者分娩前后左心室整体收缩功能的改变,为临床早期判断及治疗提供参考。
文摘目的研究MRI在评估扩张型心肌病(DCM)患者左心室收缩和心肌纤维化中的应用价值。方法选取2016年10月至2018年10月我院DCM患者53例及同期健康体检者50例分别为研究组和对照组并进行心脏磁共振(CMR)和磁共振纵向弛豫时间定量(T1 mapping)成像检查,比较两组左室舒张末期室壁厚度(TDD)、左室收缩末期室壁厚度(TSD)、室间隔基底段厚度(IVS)及左室心肌质量(LVMM)等结构参数以及左室舒张末期容积(LVEDV)、左室收缩末期容积(LVESV)、左室每搏输出量(LVSV)及左室射血分数(LVEF)等功能参数及心肌T1值并采用Pearson系数进行相关性分析。结果研究组TDD和TSD低于对照组,LVMM高于对照组;研究组LVEDV、LVESV及心肌T1值高于对照组,LVSV及LVEF低于对照组,差异有统计学意义(P<0.05);Pearson相关性分析结果显示心肌T1值与TDD、TSD、LVSV及LVEF呈负相关性,与LVEDV和LVESV呈正相关性,差异均有统计学意义(P<0.05)。结论CMR技术可准确测量D C M患者心脏结构和功能参数,直接判断患者心功能状态,T1 mapping可有效反映心肌弥漫性纤维化程度,对DCM临床诊断、病情评估和预后判断均具有重要价值。
