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Moderating Effect of Perceived Threat of Breast Cancer on Relation between Knowledge and Breast Self Examination
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作者 Carolle Annie Njopvoui Armel Valdin Teague Tsopgny Henri Rodrigue Njengoue Ngamaleu 《Psycho-Oncologie》 SCIE 2024年第1期59-68,共10页
Estimated at more than 2.2 million cases worldwide,most breast cancer cases and deaths from breast cancer occur in low and middle-income countries.In Cameroon,many studies have underlined the effect of knowledge of br... Estimated at more than 2.2 million cases worldwide,most breast cancer cases and deaths from breast cancer occur in low and middle-income countries.In Cameroon,many studies have underlined the effect of knowledge of breast cancer on screening measures such as self-examination and,to a lesser extent,the perception of the threat of this disease.This research aims to assess according to the Health Belief Model(HBM),the moderating effect of perceived threat of breast cancer on the relation between knowledge and breast self-examination.A questionnaire survey was conducted among 517 Cameroonian women to assess their general knowledge about breast cancer(risk factors and screening measures),their level of the perceived threat of breast cancer through Perceived susceptibility and severity,and the prevalence of breast self-examination amongst them.A regression analysis using the Macro Process for moderation indicates the main effect of Perceived threat(b=0,29;t(517)=2,36;p=0,02)of breast cancer and knowledge(b=0,02;t(517)=4,29;p<0,001)on breast self-examination.Results also confirm that the perceived threat of breast cancer moderates the effect of knowledge on breast self-examination.While the low level of perceived threat highlights the effect of knowledge on breast self-examination(b=0,02;t(517)=3,49;p<0,001),the high level of perceived threat cancels that effect(b=0,01;t(517)=1,97;p=0,01).A woman who perceives severity and susceptibility to breast cancer is more inclined to perform breast self-examination.This result suggests the importance of taking into account,in a context where knowledge of breast cancer is limited,relevant factors of the health belief model in preventive measures against breast cancer in general and the practice of breast self-examination in particular. 展开更多
关键词 KNOWLEDGE perceived threat breast cancer breast self-examination moderation effect HBM
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The Mediating and Moderating Effects of Family Resilience on the Relationship between Individual Resilience and Depression in Patients with Breast Cancer
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作者 Youqi Jiang Bing Wu +5 位作者 Jiahui Chen Ruyi Jin Guangshan Jin Minhao Zhang Qin Zhou Aiji Jiang 《Psycho-Oncologie》 SCIE 2024年第3期191-200,共10页
Objective:This study evaluated the effect of resilience on depression among patients with breast cancer from individual and familial perspectives by exploring the mediating and moderating effects of family resilience ... Objective:This study evaluated the effect of resilience on depression among patients with breast cancer from individual and familial perspectives by exploring the mediating and moderating effects of family resilience between individual resilience and depression.Methods:A questionnaire survey was conducted among 337 patients with breast cancer who were admitted to the Oncology Department of Jiangsu Province Hospital.The survey included demographic information,the Connor–Davidson Resilience Scale(CD-RISC),the Family Resilience Assessment Scale(FRAS),and the Chinese version of the Patient Health Questionnaire-9(PHQ-9)for Depression.The relationship among individual resilience,family resilience,and depression was analyzed using hierarchical regression and bootstrap test to assess the mediating and moderating effects of family resilience.Results:The depression scores were(13.50±5.16),the individual resilience scores were(48.62±17.50),and the family resilience scores were(105.98±24.35).Significant differences in depression scores were observed in terms of family monthly income,average weekly exercise before diagnosis,post-diagnosis interpersonal relationship quality,and overall sleep quality in the past month(p<0.05).Patients with lower individual resilience had significantly higher depression scores than those with higher resilience(F=24.314,p<0.001),and similarly,patients with lower family resilience had higher depression scores than those with higher family resilience(F=41.660,p<0.001).Individual resilience and family resilience were significantly negatively correlated with depression(r=-0.447 and-0.441,respectively,p<0.001).Hierarchical regression analysis and bootstrap test showed that family resilience(β=-0.310,p<0.001)had a partial mediating effect between individual resilience(β=-0.321,p<0.001)and depression.The indirect effect size was-0.038,the 95%CI was(-0.056,-0.020),and the direct effect ratio was 71.43%.The interaction of family resilience and individual resilience had a moderating effect on depression(B=0.166,p<0.001).Family resilience negatively moderated the relationship between individual resilience and depressive symptoms and enhanced the protective effect of individual resilience against depression with increasing family resilience.Conclusion:Family resilience has mediating and moderating effects between individual resilience and depression in patients with breast cancer. 展开更多
关键词 Breast cancer individual resilience family resilience DEPRESSION moderating effect
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Relation between Interparental Conflict and Non-Suicidal Self-Injury in Adolescents:Mediating Role of Alexithymia and Moderating Role of Resilience
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作者 Lu Jia Ye Zhang Sijia Yu 《International Journal of Mental Health Promotion》 2024年第10期837-846,共10页
Background:Adolescents frequently engage in Non-Suicidal Self-Injury(NSSI),with recent trends indicating an increase in this behavior.At the same time,Chinese adolescents have a higher incidence of NSSI than Western a... Background:Adolescents frequently engage in Non-Suicidal Self-Injury(NSSI),with recent trends indicating an increase in this behavior.At the same time,Chinese adolescents have a higher incidence of NSSI than Western adolescents.Therefore,it is necessary to explore the relationship between interparental conflict and NSSI among adolescents within the context of Chinese families.Methods:The research sample comprised 755 senior high school students(46.62%male;age M=16.82,SD=0.94 years)who completed the Interparental Conflict Child Perception Scale(CPIC),Adolescent Self-Injury Behavior Questionnaire(ASHS),Toronto Alexithymia Scale-20(TAS-20),and Scale of Adolescent Resilience(RSCA).Results:Findings suggest that interparental conflict is a significant positive predictor of NSSI(r=0.22,p<0.01).Alexithymia mediates the relation between interparental conflict and NSSI(effect size=0.09,95%CI[0.05,0.13]).Additionally,resilience moderates both the direct relation(β=−0.08,p<0.05)and the latter half of the mediating pathway(β=−0.08,p<0.05)in the moderated mediation model.Conclusion:This study indicates that interparental conflict have an impact on adolescents’NSSI in Chinese families,and alexithymia and resilience play important roles in the relationship.These findings offer valuable guidance for the prevention and intervention efforts targeting NSSI among adolescents in China and in similar family contexts. 展开更多
关键词 Interparental conflict non-suicidal self-injury ALEXITHYMIA RESILIENCE ADOLESCENT moderated mediation model
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The Moderating Effect of Organizational Identification on Occupational Stress and Insomnia Among Nurses
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作者 Jing Wang Haiyun Gai +3 位作者 Chunping Ni Juan Du Shanshan Li Huihui Yu 《Journal of Clinical and Nursing Research》 2024年第1期36-44,共9页
Objective:To explore the relationship between organizational identification,occupational stress,and insomnia among nurses and to analyze the moderating role of organizational identification between occupational stress... Objective:To explore the relationship between organizational identification,occupational stress,and insomnia among nurses and to analyze the moderating role of organizational identification between occupational stress and insomnia.Methods:Through stratified sampling,720 nurses working in a tertiary A-level hospital in Shandong Province from March to May 2021 were surveyed using an effort-reward imbalance questionnaire,an organizational identification questionnaire,and the Athens Insomnia scale.Results:Organizational identification was negatively correlated with occupational stress and insomnia(r_(1)=-0.121,P_(1)<0.01;r_(2)=-0.144,P_(2)<0.01).Occupational stress was positively correlated with insomnia(r=0.379,P<0.01).Organizational identity significantly moderated nurses’occupational stress and insomnia(β=-0.192,t=-2.558,P<0.05).Conclusion:Occupational stress and organizational identification can predict insomnia.Organizational identification could negatively mediate the relationship between occupational stress and insomnia.Improving organizational identification may help alleviate insomnia symptoms by relieving occupational stress. 展开更多
关键词 NURSE Occupational stress INSOMNIA Organizational identification moderating effect
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Seeking Health Information Online:The Moderating Effects of Problematic Situations on User Intention 被引量:4
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作者 Lidan Xia Shengli Deng Yirong Liu 《Journal of Data and Information Science》 CSCD 2017年第2期76-95,共20页
Purpose: This study investigates how online user intention in searching health information is affected by problematic situations.Design/methodology/approach: Based on the Theory of Reasoned Action, the Technology Ac... Purpose: This study investigates how online user intention in searching health information is affected by problematic situations.Design/methodology/approach: Based on the Theory of Reasoned Action, the Technology Acceptance Model, and Sense-making theory, we propose two dimensions of problematic situations: urgency and severity of health issues being searched online. Data were collected through a questionnaire survey among 214 Wuhan University students and analyzed using hierarchical regression analysis.Findings: Perceived usefulness, perceived ease of use, and subjective norm can influence user intention to seek health information online. The urgency of problematic situations has a negative moderating effect on the relationship between perceived ease of use and user intention and the relationship between subjective norm and user intention. The severity of problematic situations has a negative moderating effect on the relationship between subjective norm and user intention.Research limitations: The respondents of the survey are limited to students in one Chinese university, so whether this study's results can be applied to another population or not remains to be verified. In addition, only two dimensions of problematic situations are considered in this study. Practical implications: The paper puts forward the moderating effect of problematic situations and verifies it, which is the compensation for online health information-seeking behavior research. Besides, our analyses have implications for professional design of health care systems and related consumer information searches, and improve their performance. Originality/value: Previous work has reported the effects of problematic situation on user intention to seek health information online, ignoring its influence on other factors. This empirical study extends that work to identify the influence of problematic situation when seeking intention-behavior data in two dimensions, urgency and severity. 展开更多
关键词 Health information seeking Situation moderating effect Urgency Severity
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Relationships between Features of EmergingAdulthood, Situated Decisions toward PhysicalActivity, and Physical Activity among CollegeStudents: The Moderating Role of ExerciseIntensity Tolerance 被引量:1
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作者 Jinghua Chen Zihe Wang +5 位作者 Fabian Herold Alyx Taylor Jin Kuang Ting Wang Arthur F.Kramer Liye Zou 《International Journal of Mental Health Promotion》 2023年第11期1209-1217,共9页
A significant portion of emerging adults do not achieve recommended levels of physical activity (PA). Previous studies observedassociations between features of emerging adulthood and PA levels, while the potential psy... A significant portion of emerging adults do not achieve recommended levels of physical activity (PA). Previous studies observedassociations between features of emerging adulthood and PA levels, while the potential psychological mechanisms that mightexplain this phenomenon are not fully understood. In this context, there is some evidence that situated decisions towardphysical activity (SDPA) and exercise-intensity tolerance might influence PA level. To provide empirical support for thisassumption, the current study investigated whether (i) features of emerging adulthood are linked to SDPA, which, in turn,might affect PA engagement;(ii) exercise-intensity tolerance moderate the relationship between SDPA and PA level;and (iii)SDPA is a mediator of the relationship between features of emerging adulthood and PA levels under the prerequisite thatexercise-intensity tolerance moderates the link between SDPA and PA engagement. In this study a group of 1,706 Chinesecollege students was recruited and asked to complete a set of questionnaires assessing their SDPA, PA levels, exercise-intensitytolerance, and features associated with emerging adulthood, namely Self-exploration, Instability, and Possibility. Our resultsindicated that SDPA positively predicted PA levels and this relationship became stronger when exercise-intensity tolerance wasused as a moderator. Furthermore, it was observed that individuals with a higher level of Instability and a lower level ofPossibility during emerging adulthood exhibited a lower level of SDPA. Taken together, the results of our study providefurther insights on a potential psychological mechanism linking features of emerging adulthood and physical activity. 展开更多
关键词 Emerging adulthood situated decisions physical activity exercise-intensity tolerance moderated model
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Burden of disability in type 2 diabetes mellitus and the moderating effects of physical activity 被引量:1
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作者 Olufemi O Oyewole Ayotunde O Ale +1 位作者 Michael O Ogunlana Thavanesi Gurayah 《World Journal of Clinical Cases》 SCIE 2023年第14期3128-3139,共12页
The growing diabetic epidemic has created a substantial burden,not only on the people with diabetes but also on society at large.This mini-review discussed the limitations and patterns of disability in type 2 diabetes... The growing diabetic epidemic has created a substantial burden,not only on the people with diabetes but also on society at large.This mini-review discussed the limitations and patterns of disability in type 2 diabetes mellitus and put forward a case for the moderating effects of physical activity(PA)in the management of diabetes.The limitations and impairments associated with diabetes include vascular,neurological,cardiac,and renal impairments.Moreover,individuals participate less in their daily lives and in their instrumental activities of daily living,which negatively impacts the quality of life of individuals with diabetes.This often leads to a loss of quality of life due to disabilities,resulting in an increased rate of disability-adjusted life years among people with type 2 diabetes mellitus.Moreover,there are psychosocial sequelae of diabetes mellitus.This necessitates looking for moderating factors that may reduce the burden of the disease.PA has been shown to be one of the factors that can mitigate these burdens.PA does this in several ways,including through the benefits it confers,such as a reduction of hemoglobin A1c,a reduction of excess fat in the liver and pancreas,and the reduction of cardiovascular risk factors,all of which favorably affect glycemic parameters.Specifically,PA regulates or moderates diabetes disability through two mechanisms:The regulation of glucolipid metabolism disorders and the optimization of body mass index and systemic conditions.Therefore,efforts should be directed at PA uptake through identified strategies.This will not only prevent diabetes or diabetes complications but will reduce its burden. 展开更多
关键词 Type 2 diabetes mellitus Disability burden Physical activity moderating effect
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Antecedents of Social Network Trust in SNS Usage: The Moderating Role of Offline Familiarity
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作者 Yu Wang 《Social Networking》 2017年第2期107-134,共28页
With the rapid development of social networks, there is a focus on marketing strategies and business models that are based on social media. In the academic world, scholars believe that online trust is a key factor con... With the rapid development of social networks, there is a focus on marketing strategies and business models that are based on social media. In the academic world, scholars believe that online trust is a key factor contributing to online purchasing behavior. This article explored several factors in social media trust and verified the moderating role of offline familiarity by using relevant research on online trust in conjunction with a structure equation model. The results show that independent variables such as reputation, SNS interaction, information quality, reciprocity, satisfaction and shared values have a positive influence on trust, whereas perceived similarity does not, and information quality is the most important factor. In addition, offline familiarity significantly moderates the relations between information quality, reciprocity, reputation, shared values and social media trust. This information is important to assist companies in developing an effective social network marketing strategy. 展开更多
关键词 OFFLINE FAMILIARITY SOCIAL Network Trust moderATE Structure Equation Modeling
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Dysfunctional attitudes,social support,negative life events,and depressive symptoms in Chinese adolescents:A moderated mediation model 被引量:2
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作者 Teng-Fei Yu Li Liu +3 位作者 Lu-Ning Shang Fang-Fang Xu Zhi-Min Chen Li-Ju Qian 《World Journal of Psychiatry》 SCIE 2024年第11期1671-1680,共10页
BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLE... BACKGROUND Depression is a prevalent psychological issue in adolescents that is significantly related to negative life events(NLEs)and dysfunctional attitudes.High levels of social support can significantly buffer NLEs’effect on depression.Currently,there is limited research on how social support moderates the relationship between NLEs,dysfunctional attitudes,and depression in adolescents in China.It is imperative to investigate this moderating effect to mitigate dysfunctional attitudes in adolescent undergoing depressive mood,ultimately enhancing their overall mental health.AIM To investigate the relationship and underlying mechanisms between specific dysfunctional attitudes,social support,and depression among Chinese adolescents.METHODS This is a cross-sectional study which selected five middle schools in Shandong Province for investigation in March 2022.Participants included 795 adolescents(49.87%male,mage=15.15,SD=1.84,age range=11-18 years old).All participants completed the Dysfunctional Attitude Scale,Adolescent Life Event Scale,Beck Depression Inventory,and Social Support Rating Scale.A moderated mediation model was conducted to examine the relationship between specific dysfunctional attitudes,social support,and depression.RESULTS Results indicated that NLEs affected depression through the mediating role of specific dysfunctional attitudes(autonomy attitudesβ=0.21;perfectionismβ=0.25).Moreover,social support was found to moderate the mediating effect between NLEs,specific dysfunctional attitudes,and depressive symptoms(autonomy attitudes b2=-0.08;perfectionism b2=-0.09).CONCLUSION Dysfunctional attitudes mediated and social support moderated the relationship between NLEs and depression.Social support can buffer depression symptoms among adolescents with autonomy attitudes and perfectionism. 展开更多
关键词 DEPRESSION Dysfunctional attitudes Social support Adolescents moderated mediation model
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The Relationship Between Parent Shyness and Child Shyness: Examining the Moderating Effect of Child Gender and Parenting Style 被引量:2
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作者 Han PiGuo Wu YunPeng Gao FengQiang 《Psychology Research》 2015年第1期23-31,共9页
关键词 教养 父母 儿童 调节作用 性别 检查 随机抽样 预测效果
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The impact of the digital economy on the servitization of industrial structures: the moderating effect of human capital 被引量:1
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作者 Rong Ran Xinyuan Wang +1 位作者 Ting Wang Lei Hua 《Data Science and Management》 2023年第3期174-182,共9页
The digital economy,which was born during the late third technological revolution,has caused significant economic and societal changes.Amid sluggish global economic growth,China’s economy is facing upgrades and trans... The digital economy,which was born during the late third technological revolution,has caused significant economic and societal changes.Amid sluggish global economic growth,China’s economy is facing upgrades and transformations.The sample selection for this study was conducted from 2013 to 2020.Data related to the digital economy and servitization of the industrial structure of 30 Chinese provinces,municipalities,and autonomous regions were collected.This study presents the human capital variable,based on which an econometric analysis was conducted,and examines its moderating effect.The findings indicate that even after the replacement variable indicator’s robustness test,the relationship between the digital economy and the servitization of industrial structures remains unchanged.This study demonstrats that the quality of human capital plays a positive role in this effect.Finally,a heterogeneity test demonstrated that there are different pathways for the impact of the digital economy on the servitization of industrial structures in the eastern,central,and western regions.This study provides evidence to help researchers understand the moderating utility of human capital. 展开更多
关键词 Digital economy Human capital Industrial structure servitization moderating effect model
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Moderating variables in the relationship between mental toughness and performance in basketball
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作者 Aubrey Newland Maria Newton +2 位作者 Laura Finch Colin R.Harbke Leslie Podlog 《Journal of Sport and Health Science》 SCIE 2013年第3期184-192,共9页
Purpose: This study explored the relationship between mental toughness and college basketball performance, specifically examining possible moderating variables (gender and starting status). Methods: Male and fema... Purpose: This study explored the relationship between mental toughness and college basketball performance, specifically examining possible moderating variables (gender and starting status). Methods: Male and female (n = 197) college basketball players completed the Psychological Performance Inventory-Alternative (PPI-A), a measure of characteristics and skills consistent with mental toughness, and the PERK an objective measure of basketball performance. Results: Findings suggest that basketball performance can be partially predicted by mental toughness and starting status. Males reported greater mental toughness than females. Starters and nonstarters did not differ in mental toughness. Moderated hierarchical regression analysis indicated that mental toughness was related to performance for male players as both a main effect and interaction with starter status. For female players, in contrast, starter status was the only significant predictor of performance. Practitioners are encouraged to foster the psychological skills associated with mental toughness in females and non-starters in basketball. Conclusion: Discussion of the PPI-A as a measure of mental toughness and suggestions for its improvement are explored. A need exists for additional research on mental toughness and objective performance, as performance enhancement is a major impetus for research on mental toughness. Copyright @ 2012, Shanghai University of Sport. Production and hosting by Elsevier B.V. All rights reserved. 展开更多
关键词 BASKETBALL Mental toughness moderating variables PERFORMANCE Psychological Performance Inventory-Alternative Psychological skills
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Moderating Mechanism in the Relationship between Social Isolation and Mental Health among College Students during High-Risk Period of COVID-19 Transmission in Hubei, China
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作者 Dong Yang Chia Ching Tu +2 位作者 Zhengyan Guo Xiao Dai Chia Feng Tu 《International Journal of Mental Health Promotion》 2023年第2期193-206,共14页
This study explored the effect of perceived social isolation on the mental health of college students during the high-risk period of COVID-19 transmission in Hubei,China and the role of social support from online frie... This study explored the effect of perceived social isolation on the mental health of college students during the high-risk period of COVID-19 transmission in Hubei,China and the role of social support from online friends in alleviating this effect.The questionnaire responses of 213 college students from four universities in Hubei were included.Measurement and structural models were constructed using structural equation modeling.The findings revealed that perceived social isolation while under home quarantine was a negative predictor of the mental health of college students in Hubei.Low social support from online friends may lead to a relatively strong relationship between perceived social isolation and mental health in these college students,whereas high social support from online friends may lead to a relatively weak relationship between perceived social isolation and mental health. 展开更多
关键词 Social isolation social support mental health moderATOR HUBEI
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Moderating effect of psychological resilience on the perceived social support and loneliness in the left-behind elderly in rural areas
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作者 Yue Liu Lin Huang +3 位作者 Qin Liu Gui-Zhen Qian Huan Zou Shan Zhang 《Frontiers of Nursing》 2021年第4期357-363,共7页
Objective:To investigate the loneliness and psychological resilience with the perceived social support of the left-behind elderly in rural areas and explore the moderating effect of psychological resilience on the und... Objective:To investigate the loneliness and psychological resilience with the perceived social support of the left-behind elderly in rural areas and explore the moderating effect of psychological resilience on the understanding of social support and loneliness of the left-behind elderly in rural areas.Methods:A cross-sectional study was conducted;272 left-behind elderly people in 6 rural villages in the Sichuan Province were investigated by using the General Situation Questionnaire,Perceived Social Support Scale(PSSS),Connor-Davidson Resilience Scale(CD-RISC),and the University of California at Los Angeles Loneliness Scale(UCLA)with a stratified random cluster sampling method.Results:The loneliness score of the left-behind elderly in rural areas was 52.54±7.25,the psychological resilience score was 78(68.87),and the perceived social support score was 57(51.62).The perceived social support and psychological resilience were negatively correlated with loneliness,while the perceived social support was positively correlated with psychological resilience.The moderating effect of psychological resilience on the perceived social support and loneliness of the left-behind elderly in rural areas was−0.102(P<0.001).Conclusions:Higher level resilience is of positive significance to alleviate the negative effect of social support on loneliness.Improving the resilience of the left-behind elderly in rural areas is a beneficial exploration to promote their mental health. 展开更多
关键词 LONELINESS moderating effect perceived social support psychological resilience the left-behind elderly
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The Effect of Perceived Anonymity on Online Transgressions:The Moderating Role of Moral Excuses
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作者 ZHANG Qianju 《Psychology Research》 2023年第6期246-252,共7页
With the development of science and technology,the use of the Internet is becoming more and more widespread.However,with the popularity of the Internet,some problems have gradually surfaced.The anonymity of Internet u... With the development of science and technology,the use of the Internet is becoming more and more widespread.However,with the popularity of the Internet,some problems have gradually surfaced.The anonymity of Internet use has become a breeding ground for many acts that are contrary to public decency,and this study is conducted against this background.This study explored the impact of perceived anonymity on online transgressions and investigated the moderating effect of moral excuses.A total of 414 subjects,210 males and 204 females,participated in this experimental survey.The SPSS data analysis concluded that perceived anonymity played a significant positive predictive role on online deviance(p<0.01),and the moderating role of moral excuses was not significant.This study will be conducive to the better implementation of the action of clearing cyberspace and to the regulation of public behaviour in cyberspace. 展开更多
关键词 ANONYMITY online socialization online transgressions moral excuses moderating effects
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Marital Status as a Moderator:Exploring the Relationship between Social Engagement and Depressive Symptoms in China’s Older Adult Population
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作者 Jianlun Wu Yaping Ye +4 位作者 Man Zhang Ruichen Cong Yitao Chen Pengfei Yu Qing Guo 《Biomedical and Environmental Sciences》 SCIE CAS CSCD 2024年第10期1142-1157,共16页
Objective This study aims to explore the complex relationship between social engagement and depressive symptoms among older adults in China,focusing particularly on the moderating role of marital status.Methods This s... Objective This study aims to explore the complex relationship between social engagement and depressive symptoms among older adults in China,focusing particularly on the moderating role of marital status.Methods This study used data from the latest Chinese Longitudinal Healthy Longevity Survey(CLHLS).The analysis used the latent class analysis to delineate personality clusters and hierarchical linear regression,supplemented by the PROCESS macro,to investigate the effects of social engagement and marital status on depressive symptoms.Results The analysis encompassed 7,789 respondents(mean age:82.53[s=11.20]years),with 54%female.The personality analysis categorized participants into four clusters,with the majority(77.60%)classified as Confident Idealists,who exhibited the lowest levels of depressive symptoms.Hierarchical linear regression analysis yielded several significant findings:Higher levels of social engagement were significantly associated with fewer depressive symptoms(t=-7.932,P<0.001,B=-0.463).Marital status was a significant factor;married individuals reported fewer depressive symptoms compared to their unmarried counterparts(t=-6.368,P<0.001,B=-0.750).There was a significant moderating effect of marital status on the relationship between social engagement and depressive symptoms(t=-2.092,P=0.037,B=-0.217).Conclusion This study demonstrates that,among Chinese older adults,both social engagement and marital status significantly influence depressive symptoms.Higher social engagement,particularly in other activities like doing household chores,gardening,reading newspapers or books,and playing cards or Mahjong,is associated with fewer depressive symptoms,especially among married individuals. 展开更多
关键词 Social engagement Depressive symptoms Marital status moderATOR Older adults
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Effect of Dendrobium nobile powder combined with conventional therapy on mild to moderate fatty liver
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作者 Xi Le Yin Zhang +5 位作者 Mei Yang Jie Li Hao Wang Jin-Lin Wu Juan Deng Hong-Min Zhang 《World Journal of Gastroenterology》 SCIE CAS 2024年第45期4791-4800,共10页
BACKGROUND Nonalcoholic fatty liver disease(NAFLD)encompasses a variety of liver conditions impacting individuals who consume minimal or no alcohol.Recently,traditional Chinese medicine has been gradually used to trea... BACKGROUND Nonalcoholic fatty liver disease(NAFLD)encompasses a variety of liver conditions impacting individuals who consume minimal or no alcohol.Recently,traditional Chinese medicine has been gradually used to treat mild to moderate fatty liver,among which Dendrobium nobile Lindl.powder has been affirmed by many doctors and patients to be effective.However,there is limited research on combining this treatment with standard therapies for mild to moderate NAFLD.AIM To survey the effect of combining Dendrobium nobile Lindl.powder with standard treatment on liver function and lipid metabolism disorder in patients with mild to moderate NAFLD.METHODS Eighty patients with mild to moderate NAFLD participated in this retrospective study,classified into two groups:The observation group(n=40)and the control group(n=40).In November 2020 and November 2022,the study was conducted at People’s Hospital of Chongqing Liang Jiang New Area.The control group received standard treatment,while the observation group received Dendrobium nobile Lindl.powder based on the control group.The study compared differences in traditional Chinese medicine clinical syndrome scores,liver fibrosis treatment,liver function indicators,lipid levels,and serum inflammatory factor levels before and after treatment,and we calculated the incidence of adverse reactions for both groups.RESULTS The total effective rate was 97.50%in the observation group and 72.5%in the control group.After 8 weeks of treatment,the main and secondary symptom scores remarkably decreased,especially in the observation group(P<0.05),and there was a significant reduction in the serum levels of hyaluronic acid(HA),laminin(LN),human rocollagen III(PC III),and collagen type IV(CIV).The levels of HA,LN,PC III,and CIV were significantly lower in the observation group(P<0.05).After 8 weeks,both groups indicated remarkable improvements in liver function and blood lipid levels,with the observation group having even lower levels(P<0.05).Serum levels of interleukin-1β,tumor necrosis factor-α,and interleukin-8 also dropped significantly.The observation group had a lower rate of adverse reactions(5.00%)compared to the control group(22.50%).CONCLUSION Adding Dendrobium nobile Lindl.powder to standard treatment has been found to remarkably improve symptoms and reduce inflammation in patients with mild to moderate fatty liver disease.It also enhances hepatic function and lipid profile,ameliorates liver fibrosis indices,and lowers the risk of side effects.Consequently,this therapeutic protocol shows promise for clinical implementation and dissemination. 展开更多
关键词 Dendrobium nobile Lindl.powder Nonalcoholic fatty liver disease Combination treatment Mild to moderate fatty liver Liver function Lipid metabolism disorder
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Parental Psychological Control and Internet Gaming Disorder Tendency:A Moderated Mediation Model of Core Self-Evaluation and Intentional Self-Regulation
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作者 Zhiqiao Ji Shuhua Wei Hejuan Ding 《International Journal of Mental Health Promotion》 2024年第7期547-558,共12页
Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high... Internet gaming disorder(IGD)among junior high school students is an increasingly prominent mental health concern.It is important to look for influences behind internet gaming disorder tendency(IGDT)in the junior high school student population.The present study aimed to reveal the explanatory mechanisms underlying the association between parental psychological control(PPC)and internet gaming disorder tendency among junior high school students by testing the mediating role of core self-evaluation(CSE)and the moderating role of intentional self-regulation(ISR).Participants in present study were 735 Chinese junior high school students who completed offline self-report questionnaires on parental psychological control,core self-evaluation,intentional self-regulation,and Internet gaming disorder tendency.Analyses were conducted via mediation and moderated mediation.The results showed that:(1)Parental psychological control was positively related to junior high school students’Internet gaming disorder tendency.Core self-evaluation,and intentional self-regulation were negatively related to junior high school students’Internet gaming disorder tendency,respectively.(2)Core self-evaluation partially mediated the relationship between parental psychological control and junior high school students’Internet gaming disorder tendency.(3)Intentional self-regulation moderated the association between parental psychological control and Internet gaming disorder tendency,as well as the relationships between parental psychological control and core self-evaluation and core self-evaluation and Internet gaming disorder tendency in the mediated model.Based on these findings,we believe that there is a need to weaken parental psychological control,strengthen junior high school students’core self-evaluation and intentional self-regulation,and to recognize the important role of parents as well as their children’s personal positive traits in the healthy development of junior high school students. 展开更多
关键词 Internet gaming disorder tendency parental psychological control core self-evaluation intentional self-regulation moderated mediation model junior high school students
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Analysis of Influencing Factors of Moderate to Severe Malnutrition in Elderly Patients with Lung Cancer during Chemotherapy
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作者 Ying Li Jiaying Qin +1 位作者 Ying Gao Junying Nie 《Proceedings of Anticancer Research》 2024年第5期1-6,共6页
Objective:This study aims to identify the factors influencing moderate to severe malnutrition in elderly lung cancer patients undergoing chemotherapy and to provide a basis for developing clinical prevention and inter... Objective:This study aims to identify the factors influencing moderate to severe malnutrition in elderly lung cancer patients undergoing chemotherapy and to provide a basis for developing clinical prevention and intervention strategies.Methods:The clinical data of 150 elderly lung cancer patients who received chemotherapy were retrospectively analyzed.Demographic data,clinical characteristics,laboratory indicators,treatment plans,and other relevant information were collected.Independent risk factors for moderate to severe malnutrition during chemotherapy were identified.Results:During chemotherapy,50 patients(33.33%)developed moderate to severe malnutrition.The BMI of patients with moderate to severe malnutrition was significantly lower than that of patients with no or mild malnutrition(21.20±1.60 vs.26.14±2.31,P<0.001),and the proportion of patients with stage IV tumors was significantly higher(60.00%vs.27.00%,P<0.001).Serum pre-albumin(pre-ALB)and hemoglobin(Hb)levels in patients with moderate to severe malnutrition were significantly lower than those in patients with no or mild malnutrition(152.67±30.41 g/L vs.252.47±51.24 g/L and 102.44±10.09 g/L vs.154.21±15.18 g/L,respectively,P<0.001 for all).Conclusion:Low BMI,decreased serum pre-ALB levels,and decreased serum Hb levels before chemotherapy are independent risk factors for moderate to severe malnutrition in elderly lung cancer patients during chemotherapy.Close clinical attention should be given to these patients,with early intervention measures such as nutritional support to reduce the incidence of malnutrition and improve patients’quality of life and prognosis. 展开更多
关键词 Lung cancer CHEMOTHERAPY moderate to severe malnutrition Influencing factors
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不同强度运动抑制糖尿病大鼠肾脏PI3K/AKT/mTOR信号通路改善自噬的比较 被引量:1
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作者 周鸿雁 张译丹 +1 位作者 季威 刘霞 《中国组织工程研究》 CAS 北大核心 2025年第11期2310-2318,共9页
背景:2型糖尿病损害肾功能。研究表明运动干预可以保护肾脏;鸢尾素可以通过抑制磷脂酰肌醇3-激酶/蛋白激酶B/雷帕霉素靶蛋白信号通路恢复自噬,保护糖尿病肾病患者的肾功能。目的:探讨运动能否通过抑制肾脏磷脂酰肌醇3-激酶/蛋白激酶B/... 背景:2型糖尿病损害肾功能。研究表明运动干预可以保护肾脏;鸢尾素可以通过抑制磷脂酰肌醇3-激酶/蛋白激酶B/雷帕霉素靶蛋白信号通路恢复自噬,保护糖尿病肾病患者的肾功能。目的:探讨运动能否通过抑制肾脏磷脂酰肌醇3-激酶/蛋白激酶B/雷帕霉素靶蛋白信号通路过度激活来恢复自噬,改善肾损伤,以及分析不同方式运动产生影响的差异。方法:将6周龄的SD大鼠随机分为空白对照组(正常大鼠)和糖尿病组,其中糖尿病组大鼠经过高脂高糖喂养加腹腔注射低剂量1%链脲佐菌素(30 mg/kg)建立2型糖尿病模型。造模成功后再将糖尿病组大鼠随机分成糖尿病模型组、中强度持续运动组和高强度间歇运动组。两个运动组大鼠分别进行8周不同强度运动干预。取材后采用葡萄糖氧化酶法检测大鼠空腹血糖,使用试剂盒检测糖化血红蛋白水平,Elisa法检测血清胰岛素浓度,计算胰岛素抵抗指数,RT-PCR检测肾组织磷脂酰肌醇3-激酶、蛋白激酶B、雷帕霉素靶蛋白、Beclin-1、podocin、nephrin的基因表达量,Western Blot检测肾组织雷帕霉素靶蛋白及自噬标记蛋白LC3-1、LC3-2、Beclin-1的蛋白表达量。结果与结论:①2型糖尿病大鼠空腹血糖和糖化血红蛋白水平极显著性升高,胰岛素抵抗水平显著上升,胰岛素水平显著下降;两种运动均能使2型糖尿病大鼠空腹血糖和糖化血红蛋白水平极显著下降,胰岛素抵抗水平显著下降,胰岛素水平显著上升;与中强度持续运动组相比,高强度间歇运动组胰岛素水平显著上升。②2型糖尿病大鼠podocin、nephrin基因表达量显著降低;两种不同形式运动均能显著提高其表达;与高强度间歇运动组相比,中等强度持续性运动组足细胞相关蛋白基因表达有进一步上升趋势,但无显著性差异。③2型糖尿病大鼠肾组织磷脂酰肌醇3-激酶、蛋白激酶B、mTORC1的mRNA及蛋白的表达量显著增加,自噬标志蛋白Beclin-1、LC3-2表达量以及LC3-2/LC3-1显著降低;两种不同形式运动均能使肾组织磷脂酰肌醇3-激酶、蛋白激酶B、mTORC1的mRNA及雷帕霉素靶蛋白蛋白的表达量显著降低,自噬标志蛋白Beclin-1、LC3-2以及LC3-2/LC3-1显著升高;与中等强度持续性运动组相比,高强度间歇运动的磷脂酰肌醇3-激酶、蛋白激酶B、mTORC1的mRNA及雷帕霉素靶蛋白的蛋白表达量有进一步下降的趋势,Beclin-1、LC3-2以及LC3-2/LC3-1有进一步升高的趋势,但仅Beclin-1有显著性差异。④结果说明2型糖尿病肾脏足细胞损伤,自噬受到抑制,与磷脂酰肌醇3-激酶/蛋白激酶B/mTORC1信号通路被异常激活密切相关。高强度间歇运动和中等强度持续性运动可以保护糖尿病肾脏,减少足细胞损伤,促进自噬恢复,这可能与运动抑制磷脂酰肌醇3-激酶/蛋白激酶B/雷帕霉素靶蛋白信号通路过度激活有关。与中等强度持续性运动相比,高强度间歇运动恢复自噬的效果呈更优趋势,但足细胞蛋白表达稍有下降。 展开更多
关键词 糖尿病肾病 足细胞 自噬 高强度间歇运动 中等强度持续性运动 PI3K AKT mTOR
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