Background: Anesthetists should measure the concentration of supplemental oxygen to determine whether patients’ partial pressure of arterial oxygen (PaO2) is correct during general anesthesia. However, the standard P...Background: Anesthetists should measure the concentration of supplemental oxygen to determine whether patients’ partial pressure of arterial oxygen (PaO2) is correct during general anesthesia. However, the standard PaO2 value in obese patients in the supine position is unknown. We evaluated the PaO2 with respect to the Broca-Katsura obesity index. Materials and Methods: From January 2001 to December 2013, we evaluated 472 patients aged ≥16 years old that underwent general anesthesia in the supine position. The anesthetic charts of 472 patients with an American Society of Anesthesiologists physical status of I or II were retrospectively reviewed to investigate the PaO2. Results: In patients aged 16 to 2 was 165.7 ± 25.6 mmHg at a Broca-Katsura index of 2 was 152.1 ± 23.8 mmHg at a Broca-Katsura index of 2 tended to decrease with age from 16 to 2 tended to decrease with age from 16 to <65 years at a Broca-Katsura index of 20% to <40%.展开更多
目的分析脓毒症肺损伤患者中医证型分布状况与肺损伤相关指标及序贯性器官衰竭评分(sequential organ failure assessment,SOFA)、急性生理和慢性健康状况Ⅱ(Acute Physiology and Chronic Health EvaluationⅡ,APACHEⅡ)评分的相关性...目的分析脓毒症肺损伤患者中医证型分布状况与肺损伤相关指标及序贯性器官衰竭评分(sequential organ failure assessment,SOFA)、急性生理和慢性健康状况Ⅱ(Acute Physiology and Chronic Health EvaluationⅡ,APACHEⅡ)评分的相关性。方法选取2022年1月—2023年1月医院收治的脓毒症肺损伤患者80例,收集患者的一般资料、肺损伤相关指标[动脉血氧合指数(ratio of partial pressure of O_(2) in arterial blood to fraction of inspired oxygen,PaO_(2)/FiO_(2))、肺泡动脉氧分压差(alveolar-arterial oxygen gradient,P(A-a)O_(2))]及SOFA、APACHEⅡ评分情况,根据中医分型标准对脓毒症肺损伤患者进行分型,比较不同分型的脓毒症肺损伤患者以上各观察指标情况并分析相关性。结果脓毒症肺损伤患者以肺热壅痹证型占比最高、35.00%(28/80),其次为瘀血阻肺型27.50%(22/80),肺塞腑实型23.75%(19/80),水饮郁肺型13.75%(11/80)。不同证型的患者在性别、年龄方面差异均无统计学意义(P>0.05);不同证型的患者肺损伤指标PaO_(2)/FiO_(2)、P(A-a)O_(2)差异均有统计学意义(P<0.05);不同证型的患者SOFA、APACHEⅡ评分差异均有统计学意义(P<0.05)。肺热壅痹、瘀血阻肺、肺塞腑实、水饮郁肺证型与PaO_(2)/FiO_(2)呈显著负相关(P<0.05),与P(A-a)O_(2)、SOFA评分、APACHEⅡ评分呈显著正相关(P<0.05)。结论脓毒症肺损伤患者中医证型主要为肺热壅痹、瘀血阻肺、肺塞腑实、水饮郁肺,与肺损伤相关指标及SOFA、APACHEⅡ评分密切相关,掌握脓毒症肺损伤辨证分型特点并观察患者肺损伤相关指标及SOFA、APACHEⅡ评分变化,对疾病诊治及预后评估具有较高价值。展开更多
After irradiated by & Gy 60Co γ-ray, mice were intraperitoneally injected immediately with 0.2 ml 100 % compound blood-activating soup twice a day for 10 days. The in situ ulnar bone marrow partial pressure of ox...After irradiated by & Gy 60Co γ-ray, mice were intraperitoneally injected immediately with 0.2 ml 100 % compound blood-activating soup twice a day for 10 days. The in situ ulnar bone marrow partial pressure of oxygen (PbO2) was determined in vivo before, during and after irradiation respectively. The bone marrow sections in the same part were observed. Our results showed that the normal murine ulnar PbO2 was 12.72±1. 05kpa. During irradiation, the level of PbO2 decreased to 10. 78±1. 17 kpa (P＜0. 001). And 3 days after irradiation, PbO2 decreased to 9. 75±0. 52 kpa, suggesting that the commonly used 'blood-activating and stasis-eliminating' Chinese drugs could promote the rehabilitation and proliferation of bone marrow microvessels in the acute radiation injured mice, expand their areas, increase the oxygen supply of bone marrow microenviroment, thereby leading to PbO2 much higher increase than that of control group. It is also helpful in the proliferation and rehabilitation of hematopoietic cells.展开更多
Objective:To establish a model of pulmonary embolism in rabbits by using autologous thrombosis of rabbit ear vein, to study the method of establishing acute pulmonary embolism by using autologous thrombus and to explo...Objective:To establish a model of pulmonary embolism in rabbits by using autologous thrombosis of rabbit ear vein, to study the method of establishing acute pulmonary embolism by using autologous thrombus and to explore the diagnostic value of oxygen partial pressure in acute pulmonary embolism.Methods: Twenty rabbits were randomly divided into normal group (n=5), 7 h group, 24h group, 1 week after model establishment Group. The arterial blood gas analysis was performed on the carotid arteries of rabbits at 7 h, 24 h and 1 W after modeling.Results: Normal group oxygen partial pressure (93.15 ± 2.26) mmHg, 7 h group oxygen partial pressure (81.98 ± 1.94) mmHg, 24 h group oxygen partial pressure (84.55 ± 2.18) mmHg, 1 W group oxygen partial pressure (92.66 ± 1.92) mmHg. Normal group oxygen partial pressure and 7 h group, 24 h group oxygen partial pressure, P value was less than 0.05 and less than 0.01, indicating that the difference was statistically significant. Normal group oxygen partial pressure and 1 week group oxygen partial pressure, P value greater than 0.05, indicating that the difference was not statistically significant.Conclusion: The oxygen partial pressure was reduced at 7 h after the establishment of the acute pulmonary embolism model and failed to return to normal within 24 h. After 1 week, the embolus began to dissolve, the respiratory and circulatory system was reestablished, and the oxygen partial pressure gradually Return to normal level. Indicating that there is a positive correlation between oxygen partial pressure and acute pulmonary embolism.展开更多
Objective: to analyze the effect of optimizing emergency nursing process on the rescue of patients with chest pain. Methods: a total of 62 patients with emergency chest pain admitted to our hospital from July 2020 to ...Objective: to analyze the effect of optimizing emergency nursing process on the rescue of patients with chest pain. Methods: a total of 62 patients with emergency chest pain admitted to our hospital from July 2020 to June 2021 were randomly selected. They were divided into the control group (even number of beds) with emergency nursing and the observation group (odd number of beds) with optimized emergency nursing process. There were 31 patients in each group, and the effects after the intervention were compared. Results: after the intervention, the time spent in the rescue process of the patients in the observation group was lower than that of the control group (P < 0.05), and the hospitalization time was lower than that of the control group (P < 0.05). Meanwhile, the incidence of adverse events was also lower than that of the control group (P < 0.05), and the PaCO2 level of the patients in the observation group was significantly lower than that of the control group (P < 0.05);The PaO2 level in the observation group was higher than that in the control group (P < 0.05);The quality of life score was higher than that of the control group (P < 0.05);The satisfaction was higher than that of the control group (P < 0.05);The rescue success was also higher than that of the control group (P < 0.05). Conclusion: for emergency chest pain patients, the application of optimized emergency nursing process has a significant effect in improving the rescue success rate, reducing the incidence of adverse events, reducing the length of hospital stay, and improving the quality of life.展开更多
文摘Background: Anesthetists should measure the concentration of supplemental oxygen to determine whether patients’ partial pressure of arterial oxygen (PaO2) is correct during general anesthesia. However, the standard PaO2 value in obese patients in the supine position is unknown. We evaluated the PaO2 with respect to the Broca-Katsura obesity index. Materials and Methods: From January 2001 to December 2013, we evaluated 472 patients aged ≥16 years old that underwent general anesthesia in the supine position. The anesthetic charts of 472 patients with an American Society of Anesthesiologists physical status of I or II were retrospectively reviewed to investigate the PaO2. Results: In patients aged 16 to 2 was 165.7 ± 25.6 mmHg at a Broca-Katsura index of 2 was 152.1 ± 23.8 mmHg at a Broca-Katsura index of 2 tended to decrease with age from 16 to 2 tended to decrease with age from 16 to <65 years at a Broca-Katsura index of 20% to <40%.
文摘目的分析脓毒症肺损伤患者中医证型分布状况与肺损伤相关指标及序贯性器官衰竭评分(sequential organ failure assessment,SOFA)、急性生理和慢性健康状况Ⅱ(Acute Physiology and Chronic Health EvaluationⅡ,APACHEⅡ)评分的相关性。方法选取2022年1月—2023年1月医院收治的脓毒症肺损伤患者80例,收集患者的一般资料、肺损伤相关指标[动脉血氧合指数(ratio of partial pressure of O_(2) in arterial blood to fraction of inspired oxygen,PaO_(2)/FiO_(2))、肺泡动脉氧分压差(alveolar-arterial oxygen gradient,P(A-a)O_(2))]及SOFA、APACHEⅡ评分情况,根据中医分型标准对脓毒症肺损伤患者进行分型,比较不同分型的脓毒症肺损伤患者以上各观察指标情况并分析相关性。结果脓毒症肺损伤患者以肺热壅痹证型占比最高、35.00%(28/80),其次为瘀血阻肺型27.50%(22/80),肺塞腑实型23.75%(19/80),水饮郁肺型13.75%(11/80)。不同证型的患者在性别、年龄方面差异均无统计学意义(P>0.05);不同证型的患者肺损伤指标PaO_(2)/FiO_(2)、P(A-a)O_(2)差异均有统计学意义(P<0.05);不同证型的患者SOFA、APACHEⅡ评分差异均有统计学意义(P<0.05)。肺热壅痹、瘀血阻肺、肺塞腑实、水饮郁肺证型与PaO_(2)/FiO_(2)呈显著负相关(P<0.05),与P(A-a)O_(2)、SOFA评分、APACHEⅡ评分呈显著正相关(P<0.05)。结论脓毒症肺损伤患者中医证型主要为肺热壅痹、瘀血阻肺、肺塞腑实、水饮郁肺,与肺损伤相关指标及SOFA、APACHEⅡ评分密切相关,掌握脓毒症肺损伤辨证分型特点并观察患者肺损伤相关指标及SOFA、APACHEⅡ评分变化,对疾病诊治及预后评估具有较高价值。
文摘After irradiated by & Gy 60Co γ-ray, mice were intraperitoneally injected immediately with 0.2 ml 100 % compound blood-activating soup twice a day for 10 days. The in situ ulnar bone marrow partial pressure of oxygen (PbO2) was determined in vivo before, during and after irradiation respectively. The bone marrow sections in the same part were observed. Our results showed that the normal murine ulnar PbO2 was 12.72±1. 05kpa. During irradiation, the level of PbO2 decreased to 10. 78±1. 17 kpa (P＜0. 001). And 3 days after irradiation, PbO2 decreased to 9. 75±0. 52 kpa, suggesting that the commonly used 'blood-activating and stasis-eliminating' Chinese drugs could promote the rehabilitation and proliferation of bone marrow microvessels in the acute radiation injured mice, expand their areas, increase the oxygen supply of bone marrow microenviroment, thereby leading to PbO2 much higher increase than that of control group. It is also helpful in the proliferation and rehabilitation of hematopoietic cells.
文摘Objective:To establish a model of pulmonary embolism in rabbits by using autologous thrombosis of rabbit ear vein, to study the method of establishing acute pulmonary embolism by using autologous thrombus and to explore the diagnostic value of oxygen partial pressure in acute pulmonary embolism.Methods: Twenty rabbits were randomly divided into normal group (n=5), 7 h group, 24h group, 1 week after model establishment Group. The arterial blood gas analysis was performed on the carotid arteries of rabbits at 7 h, 24 h and 1 W after modeling.Results: Normal group oxygen partial pressure (93.15 ± 2.26) mmHg, 7 h group oxygen partial pressure (81.98 ± 1.94) mmHg, 24 h group oxygen partial pressure (84.55 ± 2.18) mmHg, 1 W group oxygen partial pressure (92.66 ± 1.92) mmHg. Normal group oxygen partial pressure and 7 h group, 24 h group oxygen partial pressure, P value was less than 0.05 and less than 0.01, indicating that the difference was statistically significant. Normal group oxygen partial pressure and 1 week group oxygen partial pressure, P value greater than 0.05, indicating that the difference was not statistically significant.Conclusion: The oxygen partial pressure was reduced at 7 h after the establishment of the acute pulmonary embolism model and failed to return to normal within 24 h. After 1 week, the embolus began to dissolve, the respiratory and circulatory system was reestablished, and the oxygen partial pressure gradually Return to normal level. Indicating that there is a positive correlation between oxygen partial pressure and acute pulmonary embolism.
文摘Objective: to analyze the effect of optimizing emergency nursing process on the rescue of patients with chest pain. Methods: a total of 62 patients with emergency chest pain admitted to our hospital from July 2020 to June 2021 were randomly selected. They were divided into the control group (even number of beds) with emergency nursing and the observation group (odd number of beds) with optimized emergency nursing process. There were 31 patients in each group, and the effects after the intervention were compared. Results: after the intervention, the time spent in the rescue process of the patients in the observation group was lower than that of the control group (P < 0.05), and the hospitalization time was lower than that of the control group (P < 0.05). Meanwhile, the incidence of adverse events was also lower than that of the control group (P < 0.05), and the PaCO2 level of the patients in the observation group was significantly lower than that of the control group (P < 0.05);The PaO2 level in the observation group was higher than that in the control group (P < 0.05);The quality of life score was higher than that of the control group (P < 0.05);The satisfaction was higher than that of the control group (P < 0.05);The rescue success was also higher than that of the control group (P < 0.05). Conclusion: for emergency chest pain patients, the application of optimized emergency nursing process has a significant effect in improving the rescue success rate, reducing the incidence of adverse events, reducing the length of hospital stay, and improving the quality of life.
