1 INTRODUCTION The tropical Indo-Pacific Oceans span over twothirds of the global tropical oceans.A major warm pool with the highest large-scale sea surface temperature of the global oceans is located in the western P...1 INTRODUCTION The tropical Indo-Pacific Oceans span over twothirds of the global tropical oceans.A major warm pool with the highest large-scale sea surface temperature of the global oceans is located in the western Pacific and eastern Indian Oceans.The climate systems over the tropical Pacific and Indian Oceans are subject to strong ocean-atmosphere coupling at multiple scales from intraseasonal to interannual,and to centennial.The展开更多
Summary： With dwindling number of new antibiotics and inappropriate use of antibiotics, the emergence and spread of antibiotics resistance occurs commonly in healthcare institutions worldwide. In China, antibiotics a...Summary： With dwindling number of new antibiotics and inappropriate use of antibiotics, the emergence and spread of antibiotics resistance occurs commonly in healthcare institutions worldwide. In China, antibiotics are commonly overprescribed and misused. This study is to assess the effect of the nationwide special campaign on antibiotic stewardship program （ASP） at specialized hospitals in China by investigating prescription information from 2011 to 2012. Data on the hospital consumption and prescription of systemic antibiotics were obtained from four specialized hospitals, including maternity, children＇s, stomatological and cancer hospitals. Systematic random sampling was used to select outpatient prescriptions and inpatient cases. A total of 105 specialized hospitals in 2011 and 121 specialized hospitals in 2012 were analysed. The defined daily doses （DDDs） per 100 inpatient days, the percentage of antibiotic use in outpatient prescriptions, and the percentage of antibiotic use in inpatient eases were used as measurements of antibiotic use. The overall antibiotic use density in the selected hospitals decreased between 2011 and 2012 from 39.37 to 26.54 DDD/100 inpatient days （P〈0.001）. The percentage of antibiotic use in outpatient prescriptions （range： 24.12%-18.71%, P=0.109） and inpatient cases （64.85%-60.10%, P=-0.006） also decreased within the two years. Significant changes were observed among regions and different hospitals within the two years. And antibiotic consumption was correlated with the type and size of specialized hospital in 2012, but not with the regions. This analysis of antibiotic consumption of specialized hospitals allows relevant comparisons for benchmarking and shows that national ASP has improved antibiotic rational use in China. The data will assist policymakers in formulating effective strategies to decrease antibiotic overuse and identify areas that require further work.展开更多
Sustainable Development Goal(SDG 4)lays solid theoretical foundation for the development of higher teacher education in improving the quality of teaching faculty nationwide.Sustainable teacher training paves a way for...Sustainable Development Goal(SDG 4)lays solid theoretical foundation for the development of higher teacher education in improving the quality of teaching faculty nationwide.Sustainable teacher training paves a way for teacher professional development in the long run.China’s“National Teacher Training Program”serves a connection between higher teacher education and K-12 teachers in multiple perspectives when exploring K-12 teachers’improvement of the essence by upgrading the initiative of the program with the assistance of educational technology and modern educational philosophy from mutual creation to mutual benefit.Direction orientation strategic design based on demand for teaching faculty,curriculum setting in modules,and characteristics creation have been carried out to upgrade the training of teacher colleges and National Teacher Training Program in the future for achieving a win-win situation between higher teacher education and K-12 education.展开更多
THE continental dynamics has become a goaI since the beginning of the 1990s and it will still bethe key subject in the 21st century. Orogenic belts, having experienced the most intensechanges of geotherm and mechanics...THE continental dynamics has become a goaI since the beginning of the 1990s and it will still bethe key subject in the 21st century. Orogenic belts, having experienced the most intensechanges of geotherm and mechanics in the lithosphere, are the important research object in thestudy of continental dynamics. For this reason, the study of orogenic belts forms a hot and dif-ficult point in the geological society and the concentration of efforts is needed for overcomingthis difficult point. China has the most orogenic belts of various types in the world, so the De-partment of Earth Sciences caught this scientific chance in the early 1990s, took the展开更多
IN recent years, a series of environmental problems have attracted wide attention in the world.As environmental changes can result from both the operations of natural factors and human ac-tivities, the international s...IN recent years, a series of environmental problems have attracted wide attention in the world.As environmental changes can result from both the operations of natural factors and human ac-tivities, the international science community has the common opinion that environmental prob-lems should be studied in a broader perspect. In other words, the earth environment should beregarded as an entity that consists of many interactive and interrelated parts. Highlighted展开更多
I. Introduction 1. The children of today will run the families of the 21st century. Their survival, protection and development decide, for the most part, the quality of a people and lay the foundation of human progres...I. Introduction 1. The children of today will run the families of the 21st century. Their survival, protection and development decide, for the most part, the quality of a people and lay the foundation of human progress as a whole. The 1990 World Summit for Children endorsed the "World Declaration on the Survival, Protection and Development of Children" and the "Plan of Action for Implementing the World Declaration on the Survival, Protection and Development of Children in the 1990s," (hereinafter referred to as "Declaration" and "Plan of Action" for short), In March 1991, Premier Li Peng signed the two documents on behalf of the Chinese Government, making a solemn commitment to this major undertaking. 2. The wholesome development of children has a bearing upon the future of China. The Communist Party of China and the Chinese Government have always paid close attention to the survival,展开更多
Bemisia tabaci(Gennadius) biotype B,called a "superbug",is one of the most harmful biotypes of this species complex worldwide.In this report,the invasive mechanism and management of B.tabaci biotype B,based ...Bemisia tabaci(Gennadius) biotype B,called a "superbug",is one of the most harmful biotypes of this species complex worldwide.In this report,the invasive mechanism and management of B.tabaci biotype B,based on our 5-year studies,are presented.Six B.tabaci biotypes,B,Q,ZHJ1,ZHJ2,ZHJ3 and FJ1,have been identified in China.Biotype B dominates the other biotypes in many regions of the country.Genetic diversity in biotype B might be induced by host plant,geographical conditions,and/or insecticidal application.The activities of CarE(carboxylesterase) and GSTs(glutathione-S-transferase) in biotype B reared on cucumber and squash were greater than on other host plants,which might have increased its resistance to insecticides.The higher activities of detoxification enzymes in biotype B might be induced by the secondary metabolites in host plants.Higher adaptive ability of biotype B adults to adverse conditions might be linked to the expression of heat shock protein genes.The indigenous B.tabaci biotypes were displaced by the biotype B within 225 d.The asymmetric mating interactions and mutualism between biotype B and begomoviruses via its host plants speed up widespread invasion and displacement of other biotypes.B.tabaci biotype B displaced Trialeurodes vaporariorum(Westwood) after 4-7 generations under glasshouse conditions.Greater adaptive ability of the biotype B to adverse conditions and its rapid population increase might be the reasons of its successful displacement of T.vaporariorum.Greater ability of the biotype B to switch to different host plants may enrich its host plants,which might enable it to better compete with T.vaporariorum.Native predatory natural enemies possess greater ability to suppress B.tabaci under field conditions.The kairomones in the 3rd and 4th instars of biotype B may provide an important stimulus in host searching and location by its parasitoids.The present results provide useful information in explaining the mechanisms of genetic diversity,evolution and molecular eco-adaptation of biotype B.Furthermore,it provides a base for sustainable management of B.tabaci using biological and ecological measures.展开更多
To date, it remains poorly understood whether astrocytes can be easily reprogrammed into neurons. Mashl and Brn2 have been previously shown to cooperate to reprogram fibroblasts into neurons. In this study, we examine...To date, it remains poorly understood whether astrocytes can be easily reprogrammed into neurons. Mashl and Brn2 have been previously shown to cooperate to reprogram fibroblasts into neurons. In this study, we examined astrocytes from 2-month-old Sprague-Dawley rats, and found that Brn2 was expressed, but Mashl was not detectable. Thus, we hypothesized that Mashl alone could be used to reprogram astrocytes into neurons. We transfected a recombinant MSCV-MASH1 plasmid into astrocytes for 72 hours, and saw that all cells expressed Mashl. One week later, we observed the changes in morphology of astrocytes, which showed typical neuro- nal characteristics. Moreover, β-tubulin expression levels were significantly higher in astrocytes expressing Mashl than in control cells. These results indicate that Mashl alone can reprogram astrocytes into neurons.展开更多
Background Immunization is a crucial preventive measure to safeguard children under five years old against a range of diseases.In China,the coverage rate of non-National Immunization Program(non-NIP)vaccines can be im...Background Immunization is a crucial preventive measure to safeguard children under five years old against a range of diseases.In China,the coverage rate of non-National Immunization Program(non-NIP)vaccines can be improved by leveraging the recommendation from public health workers.Hence,understanding the influencing factors of recommendation behaviors assume paramount importance.This study aims to investigate influencing factors of public health workers’recommendation behaviors towards non-NIP vaccines,with a particular emphasis on financial incentives.Methods A cross-sectional survey was conducted using a multi-stage sampling method in 2019 from August to October.627 public health workers were recruited from 148 community healthcare centers in ten provincial-level administrative divisions in China.An anonymous questionnaire was used to collect demographic information,attitudes towards vaccination,and recommendation behaviors towards non-NIP vaccines,includingHaemophilus influenzae type b(Hib)vaccine,pneumococcal conjugate vaccine,varicella vaccine,and rotavirus vaccine.Descriptive analysis and multivariate logistic regression analysis were adopted in this study.Results Of the 610 public health workers with complete survey data,53.8%,57.4%,84.1%,and 54.1%often recommended Hib vaccine,pneumococcal pneumonia vaccine(PCV),varicella vaccine,and rotavirus vaccine,respectively.Logistic regression revealed that gender(Hib vaccine:OR=0.4,95%CI:0.2-0.8;PCV:OR=0.4,95%CI:0.2-0.8;rotavirus vaccine:OR=0.3,95%CI:0.2-0.6),financial incentives for non-NIP vaccination(Hib vaccine:OR=1.9,95%CI:1.1-3.6;PCV:OR=2.1,95%CI:1.1-3.9;rotavirus vaccine:OR=2.0,95%CI:1.1-3.8)and perception of vaccine safety(Hib vaccine:OR=2.7,95%CI:1.1-7.0;PCV:OR=3.2,95%CI:1.2-8.0;rotavirus vaccine:OR=3.0,95%CI:1.2-7.7)were associated with public health workers’recommendation towards Hib vaccine,PCV and rotavirus vaccine.Conclusions The findings highlighted public health workers’recommendation behaviors of non-NIP vaccines in China and revealed strong association between vaccine recommendation and financial incentives.This highlights the importance of financial incentives in public health workers’recommendation toward non-NIP vaccines in China.Proper incentives are recommended for public health workers to encourage effective health promotion in immunization practices.展开更多
Good laboratory practice（GLP） plays an important role in pre-clinical studies, which are a key stage in new drug research and development（R＆D）. The development of GLP in China started in the late 1990 s. Followin...Good laboratory practice（GLP） plays an important role in pre-clinical studies, which are a key stage in new drug research and development（R＆D）. The development of GLP in China started in the late 1990 s. Following 20 years of developments, GLP system has already been established in this country. This review firstly evaluated all the institutions in this field, and described the annual number and total number of institutions, the distribution of GLP institutions, the types of GLP institutions, and the service provided by these GLP institutions. Since the initiation of the National Key Technology R＆D Program during the 11 th Five-Year Plan, it had a significant effect on the development of GLP. Therefore, the institutions which have undertaken projects from this program will be introduced later. We also described the infrastructure of hardware and software in GLP institutions along with their faults, such as variation in development and the lack of innovation.展开更多
本文汇总2014—2023年国家自然科学基金委员会医学科学部在生物医学工程/再生医学方向面上项目、青年科学基金项目与地区科学基金项目(简称“面青地项目”)的申请与资助情况,同时分析近10年相关领域的文献报道热点,为该领域的进一步高...本文汇总2014—2023年国家自然科学基金委员会医学科学部在生物医学工程/再生医学方向面上项目、青年科学基金项目与地区科学基金项目(简称“面青地项目”)的申请与资助情况,同时分析近10年相关领域的文献报道热点,为该领域的进一步高水平发展提供参考依据。回顾性收集代码H28下面青地项目的申请与资助数据资料,主要包括:资助项数与资助经费、资助项目所在依托单位与省市分布、获资助申请人的年龄与职称分布、获资助项目申请书的关键词等内容。同时,基于Web of Science数据库对近10年发表的相关方向文献关键词进行汇总,利用CiteSpace 6.2.R4软件对关键词的热点聚类及时间分布进行分析。通过分析发现:在2014—2023年中,生物医学工程/再生医学方向共资助面青地项目1279项,包括面上项目623项、青年科学基金项目599项和地区科学基金项目57项,资助经费50799万元。其中2014年的资助项目数最少,2023年的资助项目数最多。该方向的项目资助主要集中在H2808、H2809及H2810,3个代码获资助项目数与经费总和分别占全部项目的65.9%及64.6%。上海市、上海交通大学分别是获资助项目数最多的地区、依托单位,分别占比14.7%和7.0%。31~35岁的申请人获资助项目数最多,共507项,占比39.6%。近10年该方向获资助面青地项目申请书中出现频率最高的中英文关键词都与纳米相关(纳米药物和nanomedicine),而在Web of Science数据库中已发表相关方向文献的热门关键词包括biomedical engineering、tissue engineering、biomedical applications等。近年来,国家自然科学基金委员会医学科学部对生物医学工程/再生医学方向面青地项目的资助呈稳步上升趋势,资助领域广泛且重点明确,逐步建立以青年科研人员为主体的人才梯队。展开更多
文摘1 INTRODUCTION The tropical Indo-Pacific Oceans span over twothirds of the global tropical oceans.A major warm pool with the highest large-scale sea surface temperature of the global oceans is located in the western Pacific and eastern Indian Oceans.The climate systems over the tropical Pacific and Indian Oceans are subject to strong ocean-atmosphere coupling at multiple scales from intraseasonal to interannual,and to centennial.The
基金supported by grants from the General Program of National Natural Science Foundation of China(No.71073062)Major Project in Philosophy and Social Science of Ministry of Education in China(No.10JZD0027)
文摘Summary： With dwindling number of new antibiotics and inappropriate use of antibiotics, the emergence and spread of antibiotics resistance occurs commonly in healthcare institutions worldwide. In China, antibiotics are commonly overprescribed and misused. This study is to assess the effect of the nationwide special campaign on antibiotic stewardship program （ASP） at specialized hospitals in China by investigating prescription information from 2011 to 2012. Data on the hospital consumption and prescription of systemic antibiotics were obtained from four specialized hospitals, including maternity, children＇s, stomatological and cancer hospitals. Systematic random sampling was used to select outpatient prescriptions and inpatient cases. A total of 105 specialized hospitals in 2011 and 121 specialized hospitals in 2012 were analysed. The defined daily doses （DDDs） per 100 inpatient days, the percentage of antibiotic use in outpatient prescriptions, and the percentage of antibiotic use in inpatient eases were used as measurements of antibiotic use. The overall antibiotic use density in the selected hospitals decreased between 2011 and 2012 from 39.37 to 26.54 DDD/100 inpatient days （P〈0.001）. The percentage of antibiotic use in outpatient prescriptions （range： 24.12%-18.71%, P=0.109） and inpatient cases （64.85%-60.10%, P=-0.006） also decreased within the two years. Significant changes were observed among regions and different hospitals within the two years. And antibiotic consumption was correlated with the type and size of specialized hospital in 2012, but not with the regions. This analysis of antibiotic consumption of specialized hospitals allows relevant comparisons for benchmarking and shows that national ASP has improved antibiotic rational use in China. The data will assist policymakers in formulating effective strategies to decrease antibiotic overuse and identify areas that require further work.
文摘Sustainable Development Goal(SDG 4)lays solid theoretical foundation for the development of higher teacher education in improving the quality of teaching faculty nationwide.Sustainable teacher training paves a way for teacher professional development in the long run.China’s“National Teacher Training Program”serves a connection between higher teacher education and K-12 teachers in multiple perspectives when exploring K-12 teachers’improvement of the essence by upgrading the initiative of the program with the assistance of educational technology and modern educational philosophy from mutual creation to mutual benefit.Direction orientation strategic design based on demand for teaching faculty,curriculum setting in modules,and characteristics creation have been carried out to upgrade the training of teacher colleges and National Teacher Training Program in the future for achieving a win-win situation between higher teacher education and K-12 education.
文摘THE continental dynamics has become a goaI since the beginning of the 1990s and it will still bethe key subject in the 21st century. Orogenic belts, having experienced the most intensechanges of geotherm and mechanics in the lithosphere, are the important research object in thestudy of continental dynamics. For this reason, the study of orogenic belts forms a hot and dif-ficult point in the geological society and the concentration of efforts is needed for overcomingthis difficult point. China has the most orogenic belts of various types in the world, so the De-partment of Earth Sciences caught this scientific chance in the early 1990s, took the
文摘IN recent years, a series of environmental problems have attracted wide attention in the world.As environmental changes can result from both the operations of natural factors and human ac-tivities, the international science community has the common opinion that environmental prob-lems should be studied in a broader perspect. In other words, the earth environment should beregarded as an entity that consists of many interactive and interrelated parts. Highlighted
文摘I. Introduction 1. The children of today will run the families of the 21st century. Their survival, protection and development decide, for the most part, the quality of a people and lay the foundation of human progress as a whole. The 1990 World Summit for Children endorsed the "World Declaration on the Survival, Protection and Development of Children" and the "Plan of Action for Implementing the World Declaration on the Survival, Protection and Development of Children in the 1990s," (hereinafter referred to as "Declaration" and "Plan of Action" for short), In March 1991, Premier Li Peng signed the two documents on behalf of the Chinese Government, making a solemn commitment to this major undertaking. 2. The wholesome development of children has a bearing upon the future of China. The Communist Party of China and the Chinese Government have always paid close attention to the survival,
基金Supported by the National Basic Research and Development Program of China (973 Program) of China (Grant No.2009CB119200)
文摘Bemisia tabaci(Gennadius) biotype B,called a "superbug",is one of the most harmful biotypes of this species complex worldwide.In this report,the invasive mechanism and management of B.tabaci biotype B,based on our 5-year studies,are presented.Six B.tabaci biotypes,B,Q,ZHJ1,ZHJ2,ZHJ3 and FJ1,have been identified in China.Biotype B dominates the other biotypes in many regions of the country.Genetic diversity in biotype B might be induced by host plant,geographical conditions,and/or insecticidal application.The activities of CarE(carboxylesterase) and GSTs(glutathione-S-transferase) in biotype B reared on cucumber and squash were greater than on other host plants,which might have increased its resistance to insecticides.The higher activities of detoxification enzymes in biotype B might be induced by the secondary metabolites in host plants.Higher adaptive ability of biotype B adults to adverse conditions might be linked to the expression of heat shock protein genes.The indigenous B.tabaci biotypes were displaced by the biotype B within 225 d.The asymmetric mating interactions and mutualism between biotype B and begomoviruses via its host plants speed up widespread invasion and displacement of other biotypes.B.tabaci biotype B displaced Trialeurodes vaporariorum(Westwood) after 4-7 generations under glasshouse conditions.Greater adaptive ability of the biotype B to adverse conditions and its rapid population increase might be the reasons of its successful displacement of T.vaporariorum.Greater ability of the biotype B to switch to different host plants may enrich its host plants,which might enable it to better compete with T.vaporariorum.Native predatory natural enemies possess greater ability to suppress B.tabaci under field conditions.The kairomones in the 3rd and 4th instars of biotype B may provide an important stimulus in host searching and location by its parasitoids.The present results provide useful information in explaining the mechanisms of genetic diversity,evolution and molecular eco-adaptation of biotype B.Furthermore,it provides a base for sustainable management of B.tabaci using biological and ecological measures.
基金supported by the National Basic Research Program of China(973 Program),No.2010CB530400the Key Project of National Natural Science Foundation of China,No.30930111
文摘To date, it remains poorly understood whether astrocytes can be easily reprogrammed into neurons. Mashl and Brn2 have been previously shown to cooperate to reprogram fibroblasts into neurons. In this study, we examined astrocytes from 2-month-old Sprague-Dawley rats, and found that Brn2 was expressed, but Mashl was not detectable. Thus, we hypothesized that Mashl alone could be used to reprogram astrocytes into neurons. We transfected a recombinant MSCV-MASH1 plasmid into astrocytes for 72 hours, and saw that all cells expressed Mashl. One week later, we observed the changes in morphology of astrocytes, which showed typical neuro- nal characteristics. Moreover, β-tubulin expression levels were significantly higher in astrocytes expressing Mashl than in control cells. These results indicate that Mashl alone can reprogram astrocytes into neurons.
基金This work was supported by the Bill&Melinda Gates Foundation(INV034554)。
文摘Background Immunization is a crucial preventive measure to safeguard children under five years old against a range of diseases.In China,the coverage rate of non-National Immunization Program(non-NIP)vaccines can be improved by leveraging the recommendation from public health workers.Hence,understanding the influencing factors of recommendation behaviors assume paramount importance.This study aims to investigate influencing factors of public health workers’recommendation behaviors towards non-NIP vaccines,with a particular emphasis on financial incentives.Methods A cross-sectional survey was conducted using a multi-stage sampling method in 2019 from August to October.627 public health workers were recruited from 148 community healthcare centers in ten provincial-level administrative divisions in China.An anonymous questionnaire was used to collect demographic information,attitudes towards vaccination,and recommendation behaviors towards non-NIP vaccines,includingHaemophilus influenzae type b(Hib)vaccine,pneumococcal conjugate vaccine,varicella vaccine,and rotavirus vaccine.Descriptive analysis and multivariate logistic regression analysis were adopted in this study.Results Of the 610 public health workers with complete survey data,53.8%,57.4%,84.1%,and 54.1%often recommended Hib vaccine,pneumococcal pneumonia vaccine(PCV),varicella vaccine,and rotavirus vaccine,respectively.Logistic regression revealed that gender(Hib vaccine:OR=0.4,95%CI:0.2-0.8;PCV:OR=0.4,95%CI:0.2-0.8;rotavirus vaccine:OR=0.3,95%CI:0.2-0.6),financial incentives for non-NIP vaccination(Hib vaccine:OR=1.9,95%CI:1.1-3.6;PCV:OR=2.1,95%CI:1.1-3.9;rotavirus vaccine:OR=2.0,95%CI:1.1-3.8)and perception of vaccine safety(Hib vaccine:OR=2.7,95%CI:1.1-7.0;PCV:OR=3.2,95%CI:1.2-8.0;rotavirus vaccine:OR=3.0,95%CI:1.2-7.7)were associated with public health workers’recommendation towards Hib vaccine,PCV and rotavirus vaccine.Conclusions The findings highlighted public health workers’recommendation behaviors of non-NIP vaccines in China and revealed strong association between vaccine recommendation and financial incentives.This highlights the importance of financial incentives in public health workers’recommendation toward non-NIP vaccines in China.Proper incentives are recommended for public health workers to encourage effective health promotion in immunization practices.
基金National Special Project Funds(Grant No.2012ZX09302,2013ZX09302)
文摘Good laboratory practice（GLP） plays an important role in pre-clinical studies, which are a key stage in new drug research and development（R＆D）. The development of GLP in China started in the late 1990 s. Following 20 years of developments, GLP system has already been established in this country. This review firstly evaluated all the institutions in this field, and described the annual number and total number of institutions, the distribution of GLP institutions, the types of GLP institutions, and the service provided by these GLP institutions. Since the initiation of the National Key Technology R＆D Program during the 11 th Five-Year Plan, it had a significant effect on the development of GLP. Therefore, the institutions which have undertaken projects from this program will be introduced later. We also described the infrastructure of hardware and software in GLP institutions along with their faults, such as variation in development and the lack of innovation.
文摘本文汇总2014—2023年国家自然科学基金委员会医学科学部在生物医学工程/再生医学方向面上项目、青年科学基金项目与地区科学基金项目(简称“面青地项目”)的申请与资助情况,同时分析近10年相关领域的文献报道热点,为该领域的进一步高水平发展提供参考依据。回顾性收集代码H28下面青地项目的申请与资助数据资料,主要包括:资助项数与资助经费、资助项目所在依托单位与省市分布、获资助申请人的年龄与职称分布、获资助项目申请书的关键词等内容。同时,基于Web of Science数据库对近10年发表的相关方向文献关键词进行汇总,利用CiteSpace 6.2.R4软件对关键词的热点聚类及时间分布进行分析。通过分析发现:在2014—2023年中,生物医学工程/再生医学方向共资助面青地项目1279项,包括面上项目623项、青年科学基金项目599项和地区科学基金项目57项,资助经费50799万元。其中2014年的资助项目数最少,2023年的资助项目数最多。该方向的项目资助主要集中在H2808、H2809及H2810,3个代码获资助项目数与经费总和分别占全部项目的65.9%及64.6%。上海市、上海交通大学分别是获资助项目数最多的地区、依托单位,分别占比14.7%和7.0%。31~35岁的申请人获资助项目数最多,共507项,占比39.6%。近10年该方向获资助面青地项目申请书中出现频率最高的中英文关键词都与纳米相关(纳米药物和nanomedicine),而在Web of Science数据库中已发表相关方向文献的热门关键词包括biomedical engineering、tissue engineering、biomedical applications等。近年来,国家自然科学基金委员会医学科学部对生物医学工程/再生医学方向面青地项目的资助呈稳步上升趋势,资助领域广泛且重点明确,逐步建立以青年科研人员为主体的人才梯队。
