目的探讨SQL数据库技术在临床研究中的应用价值。方法基于B/S(Browser/Server,浏览器/服务器模式)体系结构,运用SQL Server 2005数据库以及ASP(Active Server Page)技术,记录和分析原始资料进行中医药防治中风后认知障碍临床应用研究。...目的探讨SQL数据库技术在临床研究中的应用价值。方法基于B/S(Browser/Server,浏览器/服务器模式)体系结构,运用SQL Server 2005数据库以及ASP(Active Server Page)技术,记录和分析原始资料进行中医药防治中风后认知障碍临床应用研究。由于该研究是多中心、大样本、入组病例约3000例,通过数据库管理系统建立病例资料数据库的方法实时收集病例的有关信息,最后进行相关分析。结果临床资料数据库管理系统的建立不仅为多中心临床研究提供了极大的便利条件并节省了时间,实现数据的实时动态管理,加强了临床研究的数据管理和监控。结论 SQL数据库技术为临床研究提供了一种有效的技术手段。展开更多
Objective： To observe the clinical efficacy of long-time needle retaining at Baihui（GV 20） in treating post-stroke cognitive impairment. Methods： A total of 60 eligible patients with post-stroke cognitive impairme...Objective： To observe the clinical efficacy of long-time needle retaining at Baihui（GV 20） in treating post-stroke cognitive impairment. Methods： A total of 60 eligible patients with post-stroke cognitive impairment were randomized into a treatment group and a control group by random digital table, 30 cases in each group. The control group was intervened by basic treatment including routine therapy in Neurology department and Western medicine rehabilitation therapy, while the treatment group was intervened by same treatment in the control group combined with long-time needle retaining at Baihui（GV 20）. Mental state of patients was evaluated by National Institute of Health stroke scale（NIHSS） and mini-mental state examination（MMSE） after 4 weeks of treatment. Results： After 4-week treatment, the NIHSS score dropped in both groups, and intra-group comparisons showed statistical significances（both P〈0.05）, and the score in the treatment group was statistically lower than that in the control group（P〈0.01）; the MMSE score in the treatment group was significantly higher than that in the control group, there was a statistical inter-group difference（P〈0.01）; the total effective rate was 93.3%, and the marked effective rate was 50.0% in the treatment group, versus 76.7% and 20.0% in the control group, there were significant differences in the total effective rate and the marked effective rate between the two groups（all P〈0.05）. Conclusion： Long-time needle retaining at Baihui（GV 20） can produce a safe valid therapeutic efficacy in treating post-stroke cognitive impairment.展开更多
Objective：To observe the effect of row needling in muscle regions combined with seven-star needle tapping on cognitive function and quality of life （QOL） in patients with post-stroke upper limb spasticity. Methods...Objective：To observe the effect of row needling in muscle regions combined with seven-star needle tapping on cognitive function and quality of life （QOL） in patients with post-stroke upper limb spasticity. Methods： A total of 448 eligible cases were randomly allocated into a treatment group and a control group, 244 in each group. Based on standard conventional treatment, cases in the treatment group received row needling in muscle regions combined with seven-star needle tapping, whereas cases in the control group took oral Western medication. After 3 weeks of treatment, the cognitive functions were assessed using comprehensive functional assessment （CFA） and mini-mental state examination （MMSE）. The O,OL was evaluated using the Chinese-version 36-item short-form health survey （SF-36）. Results： After treatment, the CFA and MMSE scores were significantly improved in both groups （P〈0.05）; and there were between-group statistical differences （P〈0.05）, showing a better effect in the treatment group than that in the control group. In addition, there were between-group statistical significances in scores of QOL （P〈0.05, P〈0.01）. Conclusion： Row needling in muscle regions combined with seven-star needle tapping can significantly improve the cognitive function and O, OL of patients with post-stroke upper limb spasticity.展开更多
Objective:To observe the clinical efficacy of Jin's three-needle therapy on post-stroke cognitive impairment(PSCI)and the effect on neuroelectrophysiology(event-related potentials).Methods:A total of 60 PSCI patie...Objective:To observe the clinical efficacy of Jin's three-needle therapy on post-stroke cognitive impairment(PSCI)and the effect on neuroelectrophysiology(event-related potentials).Methods:A total of 60 PSCI patients were selected and divided into a treatment group and a control group according to the method of random number table,with 30 cases in each group.The patients in the control group received routine treatment while the patients in the treatment group received additional Jin's three-needle therapy.The treatment for both groups lasted four weeks.Mini-mental state examination(MMSE)and Montreal cognitive assessment(MoCA)scores as well as amplitude and latency of potential 300(P300)were adopted to compare the between-group results before and after treatment.Results:Before treatment,there were no significant differences(all P>0.05)in MMSE and MoCA scores,P300 latency and P300 amplitude between the two groups.After 4 weeks of treatment,the MMSE and MoCA scores and P300 amplitudes were improved in both groups,and the P300 latencies became shorter.The results showed significant intra-group and between-group differences(all P<0.05).Conclusion:Based on the routine treatment,Jin's three-needle therapy is effective for PSCI.The mechanism is probably through its regulation on the patients'neuroelectrophysiology.展开更多
文摘目的探讨SQL数据库技术在临床研究中的应用价值。方法基于B/S(Browser/Server,浏览器/服务器模式)体系结构,运用SQL Server 2005数据库以及ASP(Active Server Page)技术,记录和分析原始资料进行中医药防治中风后认知障碍临床应用研究。由于该研究是多中心、大样本、入组病例约3000例,通过数据库管理系统建立病例资料数据库的方法实时收集病例的有关信息,最后进行相关分析。结果临床资料数据库管理系统的建立不仅为多中心临床研究提供了极大的便利条件并节省了时间,实现数据的实时动态管理,加强了临床研究的数据管理和监控。结论 SQL数据库技术为临床研究提供了一种有效的技术手段。
基金supported by Science and Technology Planning Project of Jiaxing City,Zhejiang Province,No.2016AY23078~~
文摘Objective： To observe the clinical efficacy of long-time needle retaining at Baihui（GV 20） in treating post-stroke cognitive impairment. Methods： A total of 60 eligible patients with post-stroke cognitive impairment were randomized into a treatment group and a control group by random digital table, 30 cases in each group. The control group was intervened by basic treatment including routine therapy in Neurology department and Western medicine rehabilitation therapy, while the treatment group was intervened by same treatment in the control group combined with long-time needle retaining at Baihui（GV 20）. Mental state of patients was evaluated by National Institute of Health stroke scale（NIHSS） and mini-mental state examination（MMSE） after 4 weeks of treatment. Results： After 4-week treatment, the NIHSS score dropped in both groups, and intra-group comparisons showed statistical significances（both P〈0.05）, and the score in the treatment group was statistically lower than that in the control group（P〈0.01）; the MMSE score in the treatment group was significantly higher than that in the control group, there was a statistical inter-group difference（P〈0.01）; the total effective rate was 93.3%, and the marked effective rate was 50.0% in the treatment group, versus 76.7% and 20.0% in the control group, there were significant differences in the total effective rate and the marked effective rate between the two groups（all P〈0.05）. Conclusion： Long-time needle retaining at Baihui（GV 20） can produce a safe valid therapeutic efficacy in treating post-stroke cognitive impairment.
基金supported by Scientific Research Project of Hebei Provincial Administration Bureau of Traditional Chinese Medicine,No.2009180~~
文摘Objective：To observe the effect of row needling in muscle regions combined with seven-star needle tapping on cognitive function and quality of life （QOL） in patients with post-stroke upper limb spasticity. Methods： A total of 448 eligible cases were randomly allocated into a treatment group and a control group, 244 in each group. Based on standard conventional treatment, cases in the treatment group received row needling in muscle regions combined with seven-star needle tapping, whereas cases in the control group took oral Western medication. After 3 weeks of treatment, the cognitive functions were assessed using comprehensive functional assessment （CFA） and mini-mental state examination （MMSE）. The O,OL was evaluated using the Chinese-version 36-item short-form health survey （SF-36）. Results： After treatment, the CFA and MMSE scores were significantly improved in both groups （P〈0.05）; and there were between-group statistical differences （P〈0.05）, showing a better effect in the treatment group than that in the control group. In addition, there were between-group statistical significances in scores of QOL （P〈0.05, P〈0.01）. Conclusion： Row needling in muscle regions combined with seven-star needle tapping can significantly improve the cognitive function and O, OL of patients with post-stroke upper limb spasticity.
文摘Objective:To observe the clinical efficacy of Jin's three-needle therapy on post-stroke cognitive impairment(PSCI)and the effect on neuroelectrophysiology(event-related potentials).Methods:A total of 60 PSCI patients were selected and divided into a treatment group and a control group according to the method of random number table,with 30 cases in each group.The patients in the control group received routine treatment while the patients in the treatment group received additional Jin's three-needle therapy.The treatment for both groups lasted four weeks.Mini-mental state examination(MMSE)and Montreal cognitive assessment(MoCA)scores as well as amplitude and latency of potential 300(P300)were adopted to compare the between-group results before and after treatment.Results:Before treatment,there were no significant differences(all P>0.05)in MMSE and MoCA scores,P300 latency and P300 amplitude between the two groups.After 4 weeks of treatment,the MMSE and MoCA scores and P300 amplitudes were improved in both groups,and the P300 latencies became shorter.The results showed significant intra-group and between-group differences(all P<0.05).Conclusion:Based on the routine treatment,Jin's three-needle therapy is effective for PSCI.The mechanism is probably through its regulation on the patients'neuroelectrophysiology.
