在婴儿发育早期对有机磷(organophosphate,OP)农药神经毒性的敏感性可能是最高的,然而,以往的研究对宫内有机磷农药暴露和儿童认知能力的研究结果并不一致。本研究的目的是确定孕妇尿液中有机磷农药代谢物的浓度是否与其后代6岁时的非...在婴儿发育早期对有机磷(organophosphate,OP)农药神经毒性的敏感性可能是最高的,然而,以往的研究对宫内有机磷农药暴露和儿童认知能力的研究结果并不一致。本研究的目的是确定孕妇尿液中有机磷农药代谢物的浓度是否与其后代6岁时的非言语智商(nonverbal IQ)水平呈负相关关系,并检查PON1基因对潜在效应测量的修正。本研究数据来自参与了荷兰R代研究项目(Generation R Study)的708对母婴。使用气相色谱-串联质谱法测定了孕周<18、18~25和>25周的孕妇尿液中六种二烷基磷酸酯类化合物(dialkylphosphates,DAPs)的浓度。展开更多
Routine chemical examination of urine has changed dramatically since the early days of urine testing, owing to the development of the reagent strip method for chemical analysis. Reagent strips currently provide a simp...Routine chemical examination of urine has changed dramatically since the early days of urine testing, owing to the development of the reagent strip method for chemical analysis. Reagent strips currently provide a simple, rapid means for performing medically significant chemical analysis of urine, including pH, protein, glucose, ketones, blood, bilirubin, urobilinogen, nitrite, leukocytes, and specific gravity. The study was conducted in the Medical Hospital in Berat City. A total of 480 midstream urine specimens were collected in sterile containers from urinalysis cases of women （reproductive age group） from outdoor and indoor female patients （n = 480）. A total of 240 pregnant women and 240 non-pregnant women were evaluated. The patients included were between the ages of 15-50 years. The obtained results in this study ware： 1） The percentage of glucose in pregnant women has resulted in 6.67%, while in non-pregnant women 23.34% distributed by age group; 2） 16% of pregnant women had bilirubinuria, where the highest percentage is occupied by 1＋, while in non-pregnant women 26%, where the highest percentage is occupied by 1＋; 3） Urobilinogen in pregnant women has this distribution： 11.67% of the cases included in the amount of 0.7, 82% of the cases included in the amount of 1 and only 6.34% of the quantity 1.5. Urobilinogen in non-pregnant women： 11.67% of cases are in the amount 0.7 and 72.92% of the quantity 1, while others are scattered. The material was collected in sterile cups for urine. The collected material was processed based on evidence to beakers or microscope preparations. In 5 age groups, the highest percentage is from 26 to 30 years old in the pregnant women and for the non-pregnant women 15 to 20 years old.展开更多
文摘在婴儿发育早期对有机磷(organophosphate,OP)农药神经毒性的敏感性可能是最高的,然而,以往的研究对宫内有机磷农药暴露和儿童认知能力的研究结果并不一致。本研究的目的是确定孕妇尿液中有机磷农药代谢物的浓度是否与其后代6岁时的非言语智商(nonverbal IQ)水平呈负相关关系,并检查PON1基因对潜在效应测量的修正。本研究数据来自参与了荷兰R代研究项目(Generation R Study)的708对母婴。使用气相色谱-串联质谱法测定了孕周<18、18~25和>25周的孕妇尿液中六种二烷基磷酸酯类化合物(dialkylphosphates,DAPs)的浓度。
文摘Routine chemical examination of urine has changed dramatically since the early days of urine testing, owing to the development of the reagent strip method for chemical analysis. Reagent strips currently provide a simple, rapid means for performing medically significant chemical analysis of urine, including pH, protein, glucose, ketones, blood, bilirubin, urobilinogen, nitrite, leukocytes, and specific gravity. The study was conducted in the Medical Hospital in Berat City. A total of 480 midstream urine specimens were collected in sterile containers from urinalysis cases of women （reproductive age group） from outdoor and indoor female patients （n = 480）. A total of 240 pregnant women and 240 non-pregnant women were evaluated. The patients included were between the ages of 15-50 years. The obtained results in this study ware： 1） The percentage of glucose in pregnant women has resulted in 6.67%, while in non-pregnant women 23.34% distributed by age group; 2） 16% of pregnant women had bilirubinuria, where the highest percentage is occupied by 1＋, while in non-pregnant women 26%, where the highest percentage is occupied by 1＋; 3） Urobilinogen in pregnant women has this distribution： 11.67% of the cases included in the amount of 0.7, 82% of the cases included in the amount of 1 and only 6.34% of the quantity 1.5. Urobilinogen in non-pregnant women： 11.67% of cases are in the amount 0.7 and 72.92% of the quantity 1, while others are scattered. The material was collected in sterile cups for urine. The collected material was processed based on evidence to beakers or microscope preparations. In 5 age groups, the highest percentage is from 26 to 30 years old in the pregnant women and for the non-pregnant women 15 to 20 years old.
