提出一种适合心电信号(ECG)检测的OTA-C滤波器。为了达到低功耗、低截止频率、高直流增益、高阻带衰减、低谐波失真的目的,滤波器采用五阶巴特沃斯全差分低通滤波结构和高增益的两级单端输出OTA,其中OTA电路采用亚阈值区驱动、电流分流...提出一种适合心电信号(ECG)检测的OTA-C滤波器。为了达到低功耗、低截止频率、高直流增益、高阻带衰减、低谐波失真的目的,滤波器采用五阶巴特沃斯全差分低通滤波结构和高增益的两级单端输出OTA,其中OTA电路采用亚阈值区驱动、电流分流和源极负反馈等技术。采用SMIC 0.18-μm 1P6M CMOS工艺进行电路、版图设计及优化。仿真结果表明,滤波器在静态功耗为17.6μW,截止频率为240 Hz,直流增益为-6 d B,阻带衰减大于72 d B每五倍频,三次谐波失真小于-62 d B在400 m V时,适合应用于心电信号检测模拟前端。展开更多
Respiratory monitoring is increasingly used in clinical and healthcare practices to diagnose chronic cardio-pulmonary functional diseases during various routine activities.Wearable medical devices have realized the po...Respiratory monitoring is increasingly used in clinical and healthcare practices to diagnose chronic cardio-pulmonary functional diseases during various routine activities.Wearable medical devices have realized the possibilities of ubiquitous respiratory monitoring,however,relatively little attention is paid to accuracy and reliability.In previous study,a wearable respiration biofeedback system was designed.In this work,three kinds of signals were mixed to extract respiratory rate,i.e.,respiration inductive plethysmography(RIP),3D-acceleration and ECG.In-situ experiments with twelve subjects indicate that the method significantly improves the accuracy and reliability over a dynamic range of respiration rate.It is possible to derive respiration rate from three signals within mean absolute percentage error 4.37%of a reference gold standard.Similarly studies derive respiratory rate from single-lead ECG within mean absolute percentage error 17%of a reference gold standard.展开更多
A new model based on dyadic differential wavelet was developed for detecting the R peak in Holter ECG signal according to the design of data mining. The Mallat recursive filter algorithm was introduced to calculate wa...A new model based on dyadic differential wavelet was developed for detecting the R peak in Holter ECG signal according to the design of data mining. The Mallat recursive filter algorithm was introduced to calculate wavelet and optimize the detection algorithm which is based on the equivalent filter technique. The detection algorithm has been verified by MIT arrhythmia database with a high efficiency of 99%. After optimization, the algorithm was put into clinical experiment and tested in the Air Force Hospital in Tianjin for about two months. After about 108 hearts beating test of more than 100 patients, the total efficient detection rate has reached 97%. Now this algorithm module has been applied in business software and shows perfect performance under the complex conditions such as the inversion of heart beating, the falling off of the electrodes, the excursion of base line and so on.展开更多
文摘提出一种适合心电信号(ECG)检测的OTA-C滤波器。为了达到低功耗、低截止频率、高直流增益、高阻带衰减、低谐波失真的目的,滤波器采用五阶巴特沃斯全差分低通滤波结构和高增益的两级单端输出OTA,其中OTA电路采用亚阈值区驱动、电流分流和源极负反馈等技术。采用SMIC 0.18-μm 1P6M CMOS工艺进行电路、版图设计及优化。仿真结果表明,滤波器在静态功耗为17.6μW,截止频率为240 Hz,直流增益为-6 d B,阻带衰减大于72 d B每五倍频,三次谐波失真小于-62 d B在400 m V时,适合应用于心电信号检测模拟前端。
基金Project(2012M510207)supported by the China Postdoctoral Science FoundationProjects(60932001,61072031)supported by the National Natural Science Foundation of China+2 种基金Project(2012AA02A604)supported by the National High Technology Research and Development Program of ChinaProject(2013ZX03005013)supported by the Next Generation Communication Technology Major Project of National Science and Technology,ChinaProject supported by the"One-hundred Talent"and the"Low-cost Healthcare"Programs of Chinese Academy of Sciences
文摘Respiratory monitoring is increasingly used in clinical and healthcare practices to diagnose chronic cardio-pulmonary functional diseases during various routine activities.Wearable medical devices have realized the possibilities of ubiquitous respiratory monitoring,however,relatively little attention is paid to accuracy and reliability.In previous study,a wearable respiration biofeedback system was designed.In this work,three kinds of signals were mixed to extract respiratory rate,i.e.,respiration inductive plethysmography(RIP),3D-acceleration and ECG.In-situ experiments with twelve subjects indicate that the method significantly improves the accuracy and reliability over a dynamic range of respiration rate.It is possible to derive respiration rate from three signals within mean absolute percentage error 4.37%of a reference gold standard.Similarly studies derive respiratory rate from single-lead ECG within mean absolute percentage error 17%of a reference gold standard.
文摘A new model based on dyadic differential wavelet was developed for detecting the R peak in Holter ECG signal according to the design of data mining. The Mallat recursive filter algorithm was introduced to calculate wavelet and optimize the detection algorithm which is based on the equivalent filter technique. The detection algorithm has been verified by MIT arrhythmia database with a high efficiency of 99%. After optimization, the algorithm was put into clinical experiment and tested in the Air Force Hospital in Tianjin for about two months. After about 108 hearts beating test of more than 100 patients, the total efficient detection rate has reached 97%. Now this algorithm module has been applied in business software and shows perfect performance under the complex conditions such as the inversion of heart beating, the falling off of the electrodes, the excursion of base line and so on.