下肢深静脉血栓形成(lower extremity deep venous thrombosis, LDVT)是一种临床常见的周围血管疾病,发病率逐年升高。随着传统与现代医学的发展,LDVT的治疗发生了变化。本文就近年来国内外对LDVT的相关文献资料进行综述,为临床治疗提...下肢深静脉血栓形成(lower extremity deep venous thrombosis, LDVT)是一种临床常见的周围血管疾病,发病率逐年升高。随着传统与现代医学的发展,LDVT的治疗发生了变化。本文就近年来国内外对LDVT的相关文献资料进行综述,为临床治疗提供客观依据。Lower extremity deep vein thrombosis (LDVT) is a common clinical peripheral vascular disease with an increasing incidence year by year. With the development of traditional and modern medicine, the treatment of LDVT has changed. In this paper, we review the relevant literature on LDVT at home and abroad in recent years to provide an objective basis for clinical treatment.展开更多
文摘下肢深静脉血栓形成(lower extremity deep venous thrombosis, LDVT)是一种临床常见的周围血管疾病,发病率逐年升高。随着传统与现代医学的发展,LDVT的治疗发生了变化。本文就近年来国内外对LDVT的相关文献资料进行综述,为临床治疗提供客观依据。Lower extremity deep vein thrombosis (LDVT) is a common clinical peripheral vascular disease with an increasing incidence year by year. With the development of traditional and modern medicine, the treatment of LDVT has changed. In this paper, we review the relevant literature on LDVT at home and abroad in recent years to provide an objective basis for clinical treatment.
文摘目的:分析经人工膝关节置换术(total knee arthroplasty, TKA)患者术后下肢深静脉血栓形成(deep venous thrombosis, DVT)的影响因素,并构建列线图模型预测患者术后DVT的发生风险。方法:回顾性分析2023年1月至2024年9月焦作市人民医院66例经TKA患者临床资料,根据术后患者是否发生DVT分为发生组与未发生组,收集并对比研究对象临床资料,对于存有差异的项目进行Logistic回归分析,探究影响TKA患者术后发生DVT的相关因素,通过绘制受试者工作特征曲线(receiver operating characteristiccurve, ROC)、列线图和校准曲线预测相关影响因素对于TKA患者术后发生DVT的风险。结果:本研究共纳入66例经TKA患者,共17例患者发生DVT,占比25.76%,49例患者未发生DVT,占比74.24%。通过对单因素分析的差异指标进行共线性分析发现,假体类型、术前D-二聚体、术后24 h血栓素B2(thromboxaneB2,TXB2)水平、纤维蛋白原(fibrinogen, FIB)水平不存在共线性关系(VIF≤10,容忍度≥0.1),可将上述指标纳入Logistic回归模型分析。利用多元线性回归方程计算,结果显示假体类型、术前D-二聚体、术后24 h TXB2水平、FIB水平均是影响TKA术后发生DVT的因素。绘制列线图和校准曲线,发现假体类型、术前D-二聚体、术后24 h TXB2水平、FIB水平预测TKA术后患者发生DVT的价值较高。结论:假体类型、术前D-二聚体、术后24 h TXB2水平和术后24 h FIB水平均是影响TKA术后患者发生DVT的危险因素,其在预测TKA术后DVT风险方面具有较高的应用价值。
