The geometry of a landslide dam is an important component of evaluating dam stability.However,the geometry of a natural dam commonly cannot be obtained immediately with field investigations due to their remote locatio...The geometry of a landslide dam is an important component of evaluating dam stability.However,the geometry of a natural dam commonly cannot be obtained immediately with field investigations due to their remote locations.A rapid evaluation model is presented to estimate the geometries of natural dams based on the slope of the stream,volume of landslides,and the properties of the deposit.The proposed model uses high resolution satellite images to determine the geometry of the landside dam.These satellite images are the basic information to a preliminary stability analysis of a natural dam.This study applies the proposed method to two case studies in Taiwan.One is the earthquakeinduced Lung-Chung landslide dam in Taitung,and the second is the rainfall-induced Shih-Wun landslide dam in Pingtung.展开更多
There is a need for cost-efficient methods in consumer research. Existing qualitative methods are expensive to conduct. This paper aims to improve the focus group method. The objective was to improve focus groups with...There is a need for cost-efficient methods in consumer research. Existing qualitative methods are expensive to conduct. This paper aims to improve the focus group method. The objective was to improve focus groups with different aims： shorter time conducting interviews, interview greater number of respondents, deliver results faster than traditionally analysis of data, and lower total cost. CurroCus groups of 15-45 minutes duration were tested in five different experiments, including 70 to 160 respondents in groups of 7-11 respondents. The name of the new method is formed from the word ＂Curro＂ in Latin that means speed in English, and ＂Cus＂ that is the last syllable of the word ＂focus＂, thereby forming a new word： CurroCus~ on the method. The results from testing of the CurroCus~ group method at different cases showed that trained moderators and observers could collect relevant responses in a given time for each group. It was possible to process a number of 6 to 10 respondents for each group. By conducting several successive groups, saturation of information was reached after an adequate number of CurroCus~ groups. Therefore, the total number of respondents can be optimized and results can be more precise, with reduced risk of inaccuracy. At the same time, the cost for each case can be lowered substantially, in our cases to approximately 1/10 of a traditional focus group cost. The role （skills） of the moderator is important. A disadvantage is the risk that some of the respondents are not able to express their thoughts in due time when time is limited. There is a need for more research on all parts of the CurroCus group process.展开更多
The increase of import/export of every kind of herbal products calls urgently for adequate controls. Analysis of herbal food supplement （botanicals） is a difficult task, like in the composition determination of a mu...The increase of import/export of every kind of herbal products calls urgently for adequate controls. Analysis of herbal food supplement （botanicals） is a difficult task, like in the composition determination of a multi-ingredient product, where several botanical drugs were used. Actually, this is an important argument in consideration of health security. The authors reported the results of an analytical approach based on HPTLC （high performance thin layer chromatography） fingerprints comparison and tailored to determine the composition of marketed multi-ingredient botanicals. The method gave positive data in case of the presence of 3-5 species, whereas difficulties were recorded when the number of plants is increased.展开更多
目的系统阐明灯盏生脉胶囊中的化学成分组成,并初步探究其治疗心绞痛的作用机制。方法采用超高效液相色谱-四级杆/静电场轨道阱高分辨质谱(UHPLC-Q-Orbitrap HRMS)技术对灯盏生脉胶囊中的化合物进行准确定性,并结合网络药理学分析在灯...目的系统阐明灯盏生脉胶囊中的化学成分组成,并初步探究其治疗心绞痛的作用机制。方法采用超高效液相色谱-四级杆/静电场轨道阱高分辨质谱(UHPLC-Q-Orbitrap HRMS)技术对灯盏生脉胶囊中的化合物进行准确定性,并结合网络药理学分析在灯盏生脉胶囊中治疗心绞痛过程中起调控作用的靶点及通路。结果共鉴定出黄酮类、木脂素类、酚酸类、皂苷类和其他类共5类共30种化合物,其中16种化合物为灯盏生脉胶囊入血成分,可通过调控丝裂原活化蛋白激酶(mitogen-activated protein kinases,MAPK)通路和p53通路等来发挥治疗心绞痛的作用。结论为探索灯盏生脉胶囊药效物质基础提供了新的思路,并为指导临床合理用药提供了科学的理论依据。展开更多
The new measures computed here are the spectral detrended fluctuation anatysls （sDFA） and spectral multi-taper method （sMTM）. sDFA applies the standard detrended fluctuation analysis （DFA） algorithm to power spe...The new measures computed here are the spectral detrended fluctuation anatysls （sDFA） and spectral multi-taper method （sMTM）. sDFA applies the standard detrended fluctuation analysis （DFA） algorithm to power spectra, sMTM exploits the minute increases in the broadband response, typical of chaotic spectra approaching optimal values. The authors chose the Brusselator, Lorenz, and Duffing as the proposed models to measure and locate chaos and severe irregularity. Their series of chaotic parametric responses in short time-series is advantageous. Where cycles have only a limited number of slow oscillations such as for systems biology and medicine. It is difficult to create, locate, or monitor chaos. From 50 linearly increasing starting points applied to the chaos target function （CTF）; the mean percentage increases in Kolmogorov-Sinai entropy （KS-Entropy） for the proposed chosen models; and p-values when the models were compared statistically by Kruskal-Wallis and ANOVA1 test with distributions assumed normal are Duffing （CTF： 31%： p 〈0.03）; Lorenz （CTF： 2%： p 〈0.03）, and I3russelator （CTF： 8%： p 〈0.01）. Principal component analysis （PCA） is applied to assess the significance of the objective functions for tuning the chaotic response. From PCA the conclusion is that CTF is the most beneficial objective function overall delivering the highest increases in mean KS-Entropy.展开更多
基金supported by National Science Council,Taiwan,China.The project name is Numerical Approach to Estimate the Stability and Deformation Response of Landslide Dams(NSC99-2625-M-006-004)and Modeling of The Compound Disaster in Hsiaolin Village(NSC99-2218-E-006-238)
文摘The geometry of a landslide dam is an important component of evaluating dam stability.However,the geometry of a natural dam commonly cannot be obtained immediately with field investigations due to their remote locations.A rapid evaluation model is presented to estimate the geometries of natural dams based on the slope of the stream,volume of landslides,and the properties of the deposit.The proposed model uses high resolution satellite images to determine the geometry of the landside dam.These satellite images are the basic information to a preliminary stability analysis of a natural dam.This study applies the proposed method to two case studies in Taiwan.One is the earthquakeinduced Lung-Chung landslide dam in Taitung,and the second is the rainfall-induced Shih-Wun landslide dam in Pingtung.
文摘There is a need for cost-efficient methods in consumer research. Existing qualitative methods are expensive to conduct. This paper aims to improve the focus group method. The objective was to improve focus groups with different aims： shorter time conducting interviews, interview greater number of respondents, deliver results faster than traditionally analysis of data, and lower total cost. CurroCus groups of 15-45 minutes duration were tested in five different experiments, including 70 to 160 respondents in groups of 7-11 respondents. The name of the new method is formed from the word ＂Curro＂ in Latin that means speed in English, and ＂Cus＂ that is the last syllable of the word ＂focus＂, thereby forming a new word： CurroCus~ on the method. The results from testing of the CurroCus~ group method at different cases showed that trained moderators and observers could collect relevant responses in a given time for each group. It was possible to process a number of 6 to 10 respondents for each group. By conducting several successive groups, saturation of information was reached after an adequate number of CurroCus~ groups. Therefore, the total number of respondents can be optimized and results can be more precise, with reduced risk of inaccuracy. At the same time, the cost for each case can be lowered substantially, in our cases to approximately 1/10 of a traditional focus group cost. The role （skills） of the moderator is important. A disadvantage is the risk that some of the respondents are not able to express their thoughts in due time when time is limited. There is a need for more research on all parts of the CurroCus group process.
文摘The increase of import/export of every kind of herbal products calls urgently for adequate controls. Analysis of herbal food supplement （botanicals） is a difficult task, like in the composition determination of a multi-ingredient product, where several botanical drugs were used. Actually, this is an important argument in consideration of health security. The authors reported the results of an analytical approach based on HPTLC （high performance thin layer chromatography） fingerprints comparison and tailored to determine the composition of marketed multi-ingredient botanicals. The method gave positive data in case of the presence of 3-5 species, whereas difficulties were recorded when the number of plants is increased.
文摘目的系统阐明灯盏生脉胶囊中的化学成分组成,并初步探究其治疗心绞痛的作用机制。方法采用超高效液相色谱-四级杆/静电场轨道阱高分辨质谱(UHPLC-Q-Orbitrap HRMS)技术对灯盏生脉胶囊中的化合物进行准确定性,并结合网络药理学分析在灯盏生脉胶囊中治疗心绞痛过程中起调控作用的靶点及通路。结果共鉴定出黄酮类、木脂素类、酚酸类、皂苷类和其他类共5类共30种化合物,其中16种化合物为灯盏生脉胶囊入血成分,可通过调控丝裂原活化蛋白激酶(mitogen-activated protein kinases,MAPK)通路和p53通路等来发挥治疗心绞痛的作用。结论为探索灯盏生脉胶囊药效物质基础提供了新的思路,并为指导临床合理用药提供了科学的理论依据。
文摘The new measures computed here are the spectral detrended fluctuation anatysls （sDFA） and spectral multi-taper method （sMTM）. sDFA applies the standard detrended fluctuation analysis （DFA） algorithm to power spectra, sMTM exploits the minute increases in the broadband response, typical of chaotic spectra approaching optimal values. The authors chose the Brusselator, Lorenz, and Duffing as the proposed models to measure and locate chaos and severe irregularity. Their series of chaotic parametric responses in short time-series is advantageous. Where cycles have only a limited number of slow oscillations such as for systems biology and medicine. It is difficult to create, locate, or monitor chaos. From 50 linearly increasing starting points applied to the chaos target function （CTF）; the mean percentage increases in Kolmogorov-Sinai entropy （KS-Entropy） for the proposed chosen models; and p-values when the models were compared statistically by Kruskal-Wallis and ANOVA1 test with distributions assumed normal are Duffing （CTF： 31%： p 〈0.03）; Lorenz （CTF： 2%： p 〈0.03）, and I3russelator （CTF： 8%： p 〈0.01）. Principal component analysis （PCA） is applied to assess the significance of the objective functions for tuning the chaotic response. From PCA the conclusion is that CTF is the most beneficial objective function overall delivering the highest increases in mean KS-Entropy.
