非甾体抗炎药是临床最常用的药物之一,在抗炎、解热、镇痛等方面疗效显著,此外,NSAIDs还被进一步证明可以预防多种严重疾病,包括癌症和心脏病发作。然而,多项研究数据表明NSAIDs会对胃肠道造成损害。本综述提供了NSAIDs的临床应用与引...非甾体抗炎药是临床最常用的药物之一,在抗炎、解热、镇痛等方面疗效显著,此外,NSAIDs还被进一步证明可以预防多种严重疾病,包括癌症和心脏病发作。然而,多项研究数据表明NSAIDs会对胃肠道造成损害。本综述提供了NSAIDs的临床应用与引起的胃肠道损伤,旨在不损害临床益处的情况下更安全地使用NSAIDs。Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used drugs in the clinic, with significant efficacy in anti-inflammatory, antipyretic, and analgesic effects, in addition to NSAIDs being further proven to prevent a wide range of serious illnesses, including cancer and heart attacks. However, data from several studies suggest that NSAIDs can cause damage to the gastrointestinal tract. This review provides clinical applications of NSAIDs with induced gastrointestinal damage and aims to use NSAIDs more safely without compromising clinical benefits.展开更多
文摘非甾体抗炎药是临床最常用的药物之一,在抗炎、解热、镇痛等方面疗效显著,此外,NSAIDs还被进一步证明可以预防多种严重疾病,包括癌症和心脏病发作。然而,多项研究数据表明NSAIDs会对胃肠道造成损害。本综述提供了NSAIDs的临床应用与引起的胃肠道损伤,旨在不损害临床益处的情况下更安全地使用NSAIDs。Non-steroidal anti-inflammatory drugs (NSAIDs) are one of the most commonly used drugs in the clinic, with significant efficacy in anti-inflammatory, antipyretic, and analgesic effects, in addition to NSAIDs being further proven to prevent a wide range of serious illnesses, including cancer and heart attacks. However, data from several studies suggest that NSAIDs can cause damage to the gastrointestinal tract. This review provides clinical applications of NSAIDs with induced gastrointestinal damage and aims to use NSAIDs more safely without compromising clinical benefits.