不同手术类型、手术方式以及人群的术后新发心房颤动(post-operative atrial fibrillation, POAF)发病率存在较大差异。非心脏胸外科手术后POAF在围术期较为常见,可能与炎症反应、氧化应激以及交感神经激活等多种原因有关。虽然多数房...不同手术类型、手术方式以及人群的术后新发心房颤动(post-operative atrial fibrillation, POAF)发病率存在较大差异。非心脏胸外科手术后POAF在围术期较为常见,可能与炎症反应、氧化应激以及交感神经激活等多种原因有关。虽然多数房颤表现为无症状或是一过性,但越来越多研究表明POAF会增加住院时长和费用及远期心血管不良事件的发生率。因此,识别POAF发生的危险因素并监测其预测指标,能够更有针对性地对其进行早期预防、诊断及治疗。The incidence of postoperative new-onset atrial fibrillation (POAF) varies widely depending on the type of surgery, surgical procedure, and population. POAF is more common in the perioperative period after noncardiac thoracic surgery and may be related to a variety of causes, including inflammatory response, oxidative stress, and sympathetic activation. Although most atrial fibrillation is asymptomatic or transient, several studies have shown that POAF increases the length and cost of hospitalization and the incidence of long-term adverse cardiovascular events. Therefore, identifying the risk factors for POAF and monitoring its predictive indicators will enable more targeted early prevention, diagnosis, and treatment of POAF.展开更多
文摘不同手术类型、手术方式以及人群的术后新发心房颤动(post-operative atrial fibrillation, POAF)发病率存在较大差异。非心脏胸外科手术后POAF在围术期较为常见,可能与炎症反应、氧化应激以及交感神经激活等多种原因有关。虽然多数房颤表现为无症状或是一过性,但越来越多研究表明POAF会增加住院时长和费用及远期心血管不良事件的发生率。因此,识别POAF发生的危险因素并监测其预测指标,能够更有针对性地对其进行早期预防、诊断及治疗。The incidence of postoperative new-onset atrial fibrillation (POAF) varies widely depending on the type of surgery, surgical procedure, and population. POAF is more common in the perioperative period after noncardiac thoracic surgery and may be related to a variety of causes, including inflammatory response, oxidative stress, and sympathetic activation. Although most atrial fibrillation is asymptomatic or transient, several studies have shown that POAF increases the length and cost of hospitalization and the incidence of long-term adverse cardiovascular events. Therefore, identifying the risk factors for POAF and monitoring its predictive indicators will enable more targeted early prevention, diagnosis, and treatment of POAF.