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条件性控制小鼠基因表达方法的研究进展 被引量:1
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作者 王金霞 郑志红 《实验动物与比较医学》 CAS 2008年第6期416-420,共5页
基因的时空表达和可控表达,一直是人们希望解决的问题,在小鼠中可以从DNA、转录、转录后和翻译后四个水平,通过Cre/LoxP、GAL4/UAS和条件性RNA干扰等多种方法实现。本文介绍了条件性控制小鼠基因表达的几种方法及研究进展。
关键词 基因表达 条件性控制 小鼠
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The effect of acute exercise on cognitive performance in children with and without ADHD 被引量:9
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作者 Aaron T.Piepmeier Chia-Hao Shih +6 位作者 Margaret Whedon Lauren M.Williams Matthew E.Davis David A.Henning Se Yun Park Susan D.Calkins Jennifer L.Etnier 《Journal of Sport and Health Science》 SCIE 2015年第1期97-104,共8页
Background: Attention deficit hyperactivity disorder (ADHD) is a common childhood disorder that affects approximately 11% of children in the United States. Research supports that a single session of exercise benefi... Background: Attention deficit hyperactivity disorder (ADHD) is a common childhood disorder that affects approximately 11% of children in the United States. Research supports that a single session of exercise benefits cognitive performance by children, and a limited number of studies have demonstrated that these effects can also be realized by children with ADHD. The purpose of this study was to examine the effect of acute exercise on cognitive performance by children with and without ADHD. Methods: Children with and without ADHD were asked to perform cognitive tasks on 2 days following treatment conditions that were assigned in a random, counterbalanced order. The treatment conditions consisted of a 30-min control condition on 1 day and a moderate intensity exercise condition on the other day. Results: Exercise significantly benefited performance on all three conditions of the Stroop Task, but did not significantly affect performance on the Tower of London or the Trail Making Test. Conclusion: children with and without ADHD realize benefits in speed of processing and inhibitory control in response to a session of acute exercise, but do not experience benefits in planning or set shifting. 展开更多
关键词 Executive function Physical activity Stroop Test Tower of London Test Trail Making Test
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Failure mechanism and stability control technology of rock surrounding a roadway in complex stress conditions 被引量:8
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作者 Yu Yang Bai Jianbiao +3 位作者 Chen Ke Wang Xiangyu Xiao Tongqiang Chen Yong 《Mining Science and Technology》 EI CAS 2011年第3期301-306,共6页
To solve the problem of supporting three downhill coal structures in the Yongan Coal Mine of Shanxi Jincheng, we studied the regular development of stress and plastic zones and characteristics of deformation of rock s... To solve the problem of supporting three downhill coal structures in the Yongan Coal Mine of Shanxi Jincheng, we studied the regular development of stress and plastic zones and characteristics of deformation of rock surrounding roadway groups after a period of roadway driving, mining one side as well as mining both sides, we used FLAC 3D for our numerical and theoretical analyses. Field test were carried out, where we revealed the deformation mechanism of roadways and its coal pillars in complex stress conditions. We proposed a roadway stability control technology using backwall grouting with high-water rapid hardening material and combined support with bolt and cable anchoring after mining both sides. Our field practices showed that deformation of rock surrounding roadways can be controlled with this technology. 展开更多
关键词 Both sides miningNumerical simulation FLAC3D Grouting reinforcementSupport parameters
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Determination of Internal Controls for Quantitative Gene Expression of Isochrysis zhangjiangensis at Nitrogen Stress Condition 被引量:1
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作者 WU Shuang ZHOU Jiannan +1 位作者 CAO Xupeng XUE Song 《Journal of Ocean University of China》 SCIE CAS 2016年第1期137-144,共8页
lsochrysis zhangfiangensis is a potential marine microalga for biodiesel production, which accumulates lipid under ni- trogen limitation conditions, but the mechanism on molecular level is veiled. Quantitative real-ti... lsochrysis zhangfiangensis is a potential marine microalga for biodiesel production, which accumulates lipid under ni- trogen limitation conditions, but the mechanism on molecular level is veiled. Quantitative real-time polymerase chain reaction (qPCR) provides the possibility to investigate the gene expression levels, and a valid reference for data normalization is an essential prerequisite for firing up the analysis. In this study, five housekeeping genes, actin (ACT), α-tubulin (TUA), β-tubulin (TUB), ubiquitin (UBI), 18S rRNA (18S) and one target gene, diacylglycerol acyltransferase (DGAT), were used for determining the reference. By analyzing the stabilities based on calculation of the stability index and on operating the two types of software, geNorm and bestkeeper, it showed that the reference genes widely used in higher plant and microalgae, such as UBI, TUA and 18S, were not the most stable ones in nitrogen-stressed 1. zhangjiangensis, and thus are not suitable for exploring the mRNA expression levels under these experi- mental conditions. Our results show that ACT together with TUB is the most feasible internal control for investigating gene expres- sion under nitrogen-stressed conditions. Our findings will contribute not only to future qPCR studies of/. zhangfiangensis, but also to verification of comparative transcriptomics studies of the microalgae under similar conditions. 展开更多
关键词 CHRYSOPHYTA Isochrysis zhang/iangensis nitrogen deficiency lipid accumulation reference gene selection
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ON CONTROLLABILITY FOR STOCHASTIC CONTROL SYSTEMS WHEN THE COEFFICIENT IS TIME-VARIANT 被引量:2
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作者 Feng LIU Shige PENG 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2010年第2期270-278,共9页
This paper investigates the controllability problem of time-variant linear stochastic controlsystems.A sufficient and necessary condition is established for stochastic exact controllability,whichprovides a useful alge... This paper investigates the controllability problem of time-variant linear stochastic controlsystems.A sufficient and necessary condition is established for stochastic exact controllability,whichprovides a useful algebraic criterion for stochastic control systems.Furthermore,when the stochasticsystems degenerate to deterministic systems,the algebraic criterion becomes the counterpart for thecomplete controllability of deterministic control systems. 展开更多
关键词 Backward stochastic differential equation (BSDE) E-well-posedness Stochastic controlsystem stochastic exact controllability.
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SOLVABILITY AND CONTROL DESIGN FOR SYNCHRONIZATION OF BOOLEAN NETWORKS 被引量:8
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作者 XU Xiangru HONG Yiguang 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2013年第6期871-885,共15页
This paper addresses the synchronization problem of Boolean networks.Based on the matrix expression of logic,solvability conditions and design procedures of the synchronization of Boolean networks with outputs are giv... This paper addresses the synchronization problem of Boolean networks.Based on the matrix expression of logic,solvability conditions and design procedures of the synchronization of Boolean networks with outputs are given for both open-loop and feedback control.Necessary and sufficient conditions on open-loop control are proposed first with a constructive design procedure.Then sufficient condition for the feedback control case is obtained,and corresponding design procedure is proposed with the help of algorithms to solve logic matrix equations.Numerical examples are also provided to illustrate the proposed control design. 展开更多
关键词 Boolean networks open-loop and feedback control semi-tensor product synchronization.
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Performance of ground penetrating radar in root detection and its application in root diameter estimation under controlled conditions 被引量:1
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作者 YEUNG Shan Wing YAN Wai Man HAU Chi Hang Billy 《Science China Earth Sciences》 SCIE EI CAS CSCD 2016年第1期145-155,共11页
A plant is stabilized by its root system. In congested urban cities such as Hong Kong, ground trenching is frequently seen due to the installation of utility lines along the roadside. Soil nailing, which involves soil... A plant is stabilized by its root system. In congested urban cities such as Hong Kong, ground trenching is frequently seen due to the installation of utility lines along the roadside. Soil nailing, which involves soil coring in slopes, is a common solution to improve the slope stability. However, both activities inevitably pose a risk to the integrity of any root sys- tems present, and thus reduce the root anchorage. To prevent or minimize such damage, a careful design of the excava- tion/drilling location is of prime importance. Ground penetrating radar (GPR) provides a non-destructive method for locating roots by examining the contrast between the dielectric properties of the roots and the surrounding soil. To examine the perfor- mance of GPR and promote its use in Hong Kong, a test bed was prepared using local materials to create a controlled envi- ronment in which to conduct a series of systematic tests evaluating the performance of a 900 MHz GPR. The reflected radar- grams were subject to the influence of the following factors: size and depth of roots, horizontal distance between roots, and contrast between the root and soil water content. Correlations between root size and a number of waveform parameters were also explored. Limiting values for root size, root embedded depth, horizontal separation distance between roots, and water content contrast between root and soil were obtained. A significant correlation was found between the root diameter and time travel parameter T2 (p〈0.001, t=0.795). Because GPR root detection is highly site-specific, this study provides a local refer- ence for GPR performance in the Hong Kong environment. The findings demonstrate that the 900 MHz GPR is applicable in Hong Kong for the detection of main roots. 展开更多
关键词 GPR Radar profile Root detection Root water content Root size
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On symplectic self-adjointness of Hamiltonian operator matrices 被引量:5
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作者 CHEN Alatancang JIN GuoHai WU DeYu 《Science China Mathematics》 SCIE CSCD 2015年第4期821-828,共8页
Symplectic self-adjointness of Hamiltonian operator matrices is studied, which is important to symplectic elasticity and optimal control. For the cases of diagonal domain and off-diagonal domain, necessary and suffici... Symplectic self-adjointness of Hamiltonian operator matrices is studied, which is important to symplectic elasticity and optimal control. For the cases of diagonal domain and off-diagonal domain, necessary and sufficient conditions are shown. The proofs use Frobenius-Schur factorizations of unbounded operator matrices.Under additional assumptions, sufficient conditions based on perturbation method are obtained. The theory is applied to a problem in symplectic elasticity. 展开更多
关键词 symplectic elasticity symplectic self-adjoint Hamiltonian operator matrix
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Stochastic H_2/H_∞ Control with Random Coefcients 被引量:2
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作者 Meijiao WANG 《Chinese Annals of Mathematics,Series B》 SCIE CSCD 2013年第5期733-752,共20页
Abstract This paper is concerned with the mixed H2/H∞ control for stochastic systems with random coefficients, which is actually a control combining the H2 optimization with the H∞ robust performance as the name of ... Abstract This paper is concerned with the mixed H2/H∞ control for stochastic systems with random coefficients, which is actually a control combining the H2 optimization with the H∞ robust performance as the name of H2/H∞ reveals. Based on the classical theory of linear-quadratic (LQ, for short) optimal control, the sufficient and necessary conditions for the existence and uniqueness of the solution to the indefinite backward stochastic Riccati equation (BSRE, for short) associated with H∞ robustness are derived. Then the sufficient and necessary conditions for the existence of the H2/H∞ control are given utilizing a pair of coupled stochastic Pdccati equations. 展开更多
关键词 Stochastic H∞ control Stochastic H2/H∞ control Linear quadratic(LQ) optimal control Indefinite backward stochastic Riccati equation
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OPTIMAL CONTROL OF GROWTH RATE FOR A CLASS OF POPULATION SYSTEMS
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作者 WUZhuoqun GAOHang 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2003年第1期53-66,共14页
In this paper,we discuss the optimal control of growth rate for a class of population systems governed by nonlinear degenerate parabolic equations.Given an ap-propriate cost functional,we prove the existence of the op... In this paper,we discuss the optimal control of growth rate for a class of population systems governed by nonlinear degenerate parabolic equations.Given an ap-propriate cost functional,we prove the existence of the optimal growth rate and give some necessary conditions for optimal growth rate. 展开更多
关键词 EXISTENCE necessary condition optimal growth rate population system.
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Darcy–Forchheimer Three-Dimensional Flow of Williamson Nanofluid over a Convectively Heated Nonlinear Stretching Surface 被引量:4
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作者 Tasawar Hayat Arsalan Aziz +1 位作者 Taseer Muhammad Ahmed Alsaedi 《Communications in Theoretical Physics》 SCIE CAS CSCD 2017年第9期387-394,共8页
The present study elaborates three-dimensional flow of Williamson nanoliquid over a nonlinear stretchable surface. Fluid flow obeys Darcy–Forchheimer porous medium. A bidirectional nonlinear stretching surface genera... The present study elaborates three-dimensional flow of Williamson nanoliquid over a nonlinear stretchable surface. Fluid flow obeys Darcy–Forchheimer porous medium. A bidirectional nonlinear stretching surface generates the flow. Convective surface condition of heat transfer is taken into consideration. Further the zero nanoparticles mass flux condition is imposed at the boundary. Effects of thermophoresis and Brownian diffusion are considered. Assumption of boundary layer has been employed in the problem formulation. Convergent series solutions for the nonlinear governing system are established through the optimal homotopy analysis method(OHAM). Graphs have been sketched in order to analyze that how the velocity, temperature and concentration distributions are affected by distinct emerging flow parameters. Skin friction coefficients and local Nusselt number are also computed and discussed. 展开更多
关键词 three-dimensional flow Williamson fluid nanoparticles Darcy-Forchheimer porous medium con-vective boundary condition nonlinear stretching surface
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The Effects of Redundant Control Inputs in Finite-Time Optimal Control 被引量:1
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作者 XIA Yaping CAI Chenxiao +1 位作者 YIN Minghui ZOU Yun 《Journal of Systems Science & Complexity》 SCIE EI CSCD 2016年第6期1553-1564,共12页
This paper is concerned with the effects of redundant control inputs on the quadratic optimal performance index in finite-time optimal control.Actually,the effects of redundant control input on quadratic performance i... This paper is concerned with the effects of redundant control inputs on the quadratic optimal performance index in finite-time optimal control.Actually,the effects of redundant control input on quadratic performance index is equal to study the effects of the redundant control input on the solution of Riccati differential equation(RDE).Hence,some sufficient conditions are presented to strictly decrease the solution of RDE with the column of input matrix increased.Especially,a necessary and sufficient condition is derived to strictly decrease the solution of the homogeneous RDE after control input extensions.Moreover,one sufficient condition is obtained,which guarantees that the minimum control energy index strictly decreases with input extension.It is shown that redundant control inputs can improve the system performance based on these results.Some examples are taken to illustrate the effectiveness of related problems. 展开更多
关键词 Optimal control quadratic performance index RDE redundant control.
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