背景:C反应蛋白–白蛋白–淋巴细胞(CALLY)指数在具有免疫过程的疾病中显示出良好的前景。然而,有关其在皮肌炎中的应用的研究还很有限。这项回顾性研究旨在评估CALLY对皮肌炎患者的间质性肺病和疾病活动度的预测价值。方法:我们收集了...背景:C反应蛋白–白蛋白–淋巴细胞(CALLY)指数在具有免疫过程的疾病中显示出良好的前景。然而,有关其在皮肌炎中的应用的研究还很有限。这项回顾性研究旨在评估CALLY对皮肌炎患者的间质性肺病和疾病活动度的预测价值。方法:我们收集了105位皮肌炎患者(45位患有间质性肺炎,60位无间质性肺炎)和102名健康对照者的临床数据。从电子医疗记录中提取临床特征,采用二元逻辑回归和ROC曲线分析CALLY、临床特征和疾病活动度之间的相关性。结果:皮肌炎患者的CALLY水平明显低于对照组(P Background: The C-reactive protein-albumin-lymphocyte (CALLY) index has demonstrated potential in assessing diseases with immunological processes. However, investigations into its applicability in dermatomyositis (DM) remain limited. This retrospective study aims to assess the predictive value of the CALLY index for interstitial lung disease and disease activity in patients with dermatomyositis. Methods: Data from 105 patients with DM (45 with interstitial lung disease [ILD], 60 without ILD) and 102 healthy controls were collected. Relevant clinical characteristics were extracted from medical records. Logistic regression and receiver operating characteristic (ROC) curve analyses were employed to examine correlations among CALLY, clinical characteristics, and disease activity. Results: Patients with DM demonstrated significantly lower CALLY values compared to controls (P < 0.001). Within the DM cohort, patients with ILD exhibited significantly lower CALLY values than those without ILD (P <0.05). CALLY showed a negative correlation with the global Visual Analogue Scale (VAS) score (r = −0.305, P = 0.002). ROC analysis determined the optimal CALLY cutoff value for predicting non-ILD in DM patients to be 8.41 (sensitivity 91.1%, specificity 40%, area under the ROC curve = 0.620). CALLY (P = 0.005) was identified as an independent predictor of DM without concurrent ILD. Conclusions: The CALLY index demonstrated a significant association with the absence of interstitial lung disease and reduced disease activity in patients with DM, indicating its potential utility in the assessment and monitoring of dermatomyositis.展开更多
本文对上海市高校普通大学生与湖北省武汉市高校普通大学生的一、二、三年级的大学生进行了简单问卷调查,通过文献资料法、问卷调查法及数理统计法分析,在当代社会背景下大学生体育参与活动度及体育态度的行为习惯与行为意向;了解大学...本文对上海市高校普通大学生与湖北省武汉市高校普通大学生的一、二、三年级的大学生进行了简单问卷调查,通过文献资料法、问卷调查法及数理统计法分析,在当代社会背景下大学生体育参与活动度及体育态度的行为习惯与行为意向;了解大学生的体育参与活动度以及从行为习惯和行为意向了解大学生体育态度,为体育教育事业的发展提供基础建议。In this paper, a simple questionnaire survey was conducted among college students in Shanghai and Wuhan, Hubei Province. Through the analysis of literature, questionnaires and mathematical statistics, the behavior habits and intentions of college students’ sports participation and sports attitude in the contemporary social background were analyzed. Understanding college students’ participation in sports activities and the attitude of ordinary college students to sports from their behavior habits and intentions will provide basic suggestions for the development of physical education.展开更多
文摘背景:C反应蛋白–白蛋白–淋巴细胞(CALLY)指数在具有免疫过程的疾病中显示出良好的前景。然而,有关其在皮肌炎中的应用的研究还很有限。这项回顾性研究旨在评估CALLY对皮肌炎患者的间质性肺病和疾病活动度的预测价值。方法:我们收集了105位皮肌炎患者(45位患有间质性肺炎,60位无间质性肺炎)和102名健康对照者的临床数据。从电子医疗记录中提取临床特征,采用二元逻辑回归和ROC曲线分析CALLY、临床特征和疾病活动度之间的相关性。结果:皮肌炎患者的CALLY水平明显低于对照组(P Background: The C-reactive protein-albumin-lymphocyte (CALLY) index has demonstrated potential in assessing diseases with immunological processes. However, investigations into its applicability in dermatomyositis (DM) remain limited. This retrospective study aims to assess the predictive value of the CALLY index for interstitial lung disease and disease activity in patients with dermatomyositis. Methods: Data from 105 patients with DM (45 with interstitial lung disease [ILD], 60 without ILD) and 102 healthy controls were collected. Relevant clinical characteristics were extracted from medical records. Logistic regression and receiver operating characteristic (ROC) curve analyses were employed to examine correlations among CALLY, clinical characteristics, and disease activity. Results: Patients with DM demonstrated significantly lower CALLY values compared to controls (P < 0.001). Within the DM cohort, patients with ILD exhibited significantly lower CALLY values than those without ILD (P <0.05). CALLY showed a negative correlation with the global Visual Analogue Scale (VAS) score (r = −0.305, P = 0.002). ROC analysis determined the optimal CALLY cutoff value for predicting non-ILD in DM patients to be 8.41 (sensitivity 91.1%, specificity 40%, area under the ROC curve = 0.620). CALLY (P = 0.005) was identified as an independent predictor of DM without concurrent ILD. Conclusions: The CALLY index demonstrated a significant association with the absence of interstitial lung disease and reduced disease activity in patients with DM, indicating its potential utility in the assessment and monitoring of dermatomyositis.
文摘本文对上海市高校普通大学生与湖北省武汉市高校普通大学生的一、二、三年级的大学生进行了简单问卷调查,通过文献资料法、问卷调查法及数理统计法分析,在当代社会背景下大学生体育参与活动度及体育态度的行为习惯与行为意向;了解大学生的体育参与活动度以及从行为习惯和行为意向了解大学生体育态度,为体育教育事业的发展提供基础建议。In this paper, a simple questionnaire survey was conducted among college students in Shanghai and Wuhan, Hubei Province. Through the analysis of literature, questionnaires and mathematical statistics, the behavior habits and intentions of college students’ sports participation and sports attitude in the contemporary social background were analyzed. Understanding college students’ participation in sports activities and the attitude of ordinary college students to sports from their behavior habits and intentions will provide basic suggestions for the development of physical education.
