目的探讨不同温度的灌注液对肩关节镜手术病人术后肿胀、疼痛及肩关节功能的影响。方法选取我院2019年1月至2020年1月行肩关节镜择期手术的病人200例,采用随机数字表法将病人分为观察组和对照组,每组各100例。观察组病人采用37℃灌注液...目的探讨不同温度的灌注液对肩关节镜手术病人术后肿胀、疼痛及肩关节功能的影响。方法选取我院2019年1月至2020年1月行肩关节镜择期手术的病人200例,采用随机数字表法将病人分为观察组和对照组,每组各100例。观察组病人采用37℃灌注液进行术中灌注,对照组病人采用22℃~24℃的常温灌注液。观察两组病人低体温及寒战发生情况;测量两组病人术前、术后即刻、术后24 h的臂围和肩周径,并计算术后臂围和肩周径与术前差值;应用疼痛视觉模拟量表(visual analogue scale,VAS)评估病人术前、术后24 h和48 h的疼痛情况;采用美国肩肘外科协会(American Society of Shoulder and Elbow Surgery,ASES)评分评估病人术后3个月和6个月肩关节功能恢复情况。结果观察组发生低体温5例(5%)及寒战2例(2%),明显低于对照组的11例(11%)和4例(4%)。观察组术后即刻、术后24 h与术前臂围及肩周径的差值较对照明显缩小,差异均有统计学意义(P均<0.05)。观察组术后24 h和48 h VAS评分较对照组改善明显,差异均有统计学意义(P均<0.05)。两组术后3个月和6个月ASES评分的差异均无统计学意义(P均>0.05)。结论肩关节镜手术中采用37℃恒温灌注液,能降低术中低体温及寒战的发生率,减轻病人术后关节肿胀和疼痛,有利于病人术后的快速康复,在临床中有推广价值。展开更多
A 3D ultrasound thermal model with a 3D finite element representation for modeling the thermal diffusion effects for hepatic ablation induced by spherical-section ultrasound phased array was developed. The model was f...A 3D ultrasound thermal model with a 3D finite element representation for modeling the thermal diffusion effects for hepatic ablation induced by spherical-section ultrasound phased array was developed. The model was first validated against available published measured data in rat liver. Using the validated model,effects of blood perfusion and heating schemes on lesion formation were studied for both single focus and split-focus intensity patterns. It was shown that for single focus sonication pattern the short-duration(～2 s) and high-intensity(～1250 W/cm2) heating scheme can completely reduce the cooling effect of the blood perfusion. The lesion shape and size were significantly altered by perfusion for split-focus pattern even with a rapid heating scheme when the focus spacing was larger than 2.4 mm. Underdosed areas might be present between two foci. Prolonging ex-posure time or shortening focus spacing can reduce the cool region between two foci. In addition,the influences of thermal and acoustic parameters were also studied. When the therapy depth is short(<5 cm) ,the lesion size monotonically increases with increasing attenuation coefficient that ranges from 5.4 to 11 Np/(m?MHz) .展开更多
Objective To investigate whether the impairment of grafted livers after transplantation was induced by the same inflammatory cells both in cold and warm ischemia. Methods Male SD rats were divided into two groups at r...Objective To investigate whether the impairment of grafted livers after transplantation was induced by the same inflammatory cells both in cold and warm ischemia. Methods Male SD rats were divided into two groups at random,24 donor livers in each group were stored in Ringers solution at 4℃ for 120min or 240min of transplantation for blood sample and tissue specimen collection. Results Along with the prolongation of cold and warm ischemia time,the serum ALT,AST and LDH level increased gradually after transplantation.Under light microscopy,some hepatocytes presented necrosis after 3h and 6h of transplantation in cold ischemia,and neutrophilic infiltration in sinusoids were evident.Also,a large number of hepatocytes were necrotic 3h or 6h after transplantation in warm ischemia from NHBDs,and lymphocytic infiltration was evident in the sinusoids.The findings in electron microscopy was as the same as those of light microscopy,and the cells which infiltrated the sinusoids in warm ischemia were identified as T lymphocytes. Conclusion The impairment of grafted livers after transplantation appeared to be induced by two different kinds of inflammatory cells in cold and warm ischemia,that is,neutrophils mediated the cold ischemia-reperfusion,and T lymphocytes mediated the warm ischemia-reperfusion from NHBDs,but these findings are to be comfirmed in further investigations.展开更多
Objective: To study the mechanism and effects of different scraping techniques on body surface blood perfusion volume and local skin temperature of healthy subjects and to provide a baseline for microcirculation and e...Objective: To study the mechanism and effects of different scraping techniques on body surface blood perfusion volume and local skin temperature of healthy subjects and to provide a baseline for microcirculation and energy metabolism for the evaluation of the therapeutic effects of scraping. Methods: Changes of the local blood perfusion volume and skin temperature of healthy subjects before and after applying different scraping techniques were observed with a laser Doppler imager combined with an infrared thermographic device and the resulting data was analyzed with imaging and processing software for statistical analysis. Results: Local blood perfusion volume and skin temperature all increased after both reinforcing and reducing scraping techniques. The value of blood flow 60 and 90 min after the reducing technique was significantly higher than that after the reinforcing technique (P<0.01), while the skin temperature increased after both techniques but was not significantly different between the two (P>0.05). Conclusion: Scraping can significantly improve the local blood perfusion volume, increase skin temperature and promote local blood circulation and metabolism of tissues.展开更多
Blinking is regarded as the continuous interrupted eyelid closure or opening and its thermal effect will compromise between these two. During a blink, the heat loss via convection, radiation and tear evaporation from ...Blinking is regarded as the continuous interrupted eyelid closure or opening and its thermal effect will compromise between these two. During a blink, the heat loss via convection, radiation and tear evaporation from cornea is prevented, warm tear is lay- ered across corneal surface and the vessels of the palpebral conjunctiva provide heat to anterior eye. In most of the thermal models in human eye that are found in literatures, effect of blinking is not included, simulation is carried out only in open eye. Thus, in this paper, thermal effects of blinking are investigated using one-dimensional finite element method in transient state case. The bio-heat transfer process is simulated during different blinking rates, lid closure and opening. The simulation is carried out using normal and extreme values of ambient temperatures, blood temperatures, evaporation rates, blood perfusion rates, and lens thermal conduetivities. Blinking is found to increase corneal and lens temperature by 1.29℃ and 0.78℃ respectively when compared to open eye. The results obtained from this model are useful in predicting temperature distribution in different laser eye surgeries, hyperthermia and cryosurgery treatment of eyelid carci- noma, choroidal melanoma and can be used for diagnosing temperature-related diseases.展开更多
文摘目的探讨不同温度的灌注液对肩关节镜手术病人术后肿胀、疼痛及肩关节功能的影响。方法选取我院2019年1月至2020年1月行肩关节镜择期手术的病人200例,采用随机数字表法将病人分为观察组和对照组,每组各100例。观察组病人采用37℃灌注液进行术中灌注,对照组病人采用22℃~24℃的常温灌注液。观察两组病人低体温及寒战发生情况;测量两组病人术前、术后即刻、术后24 h的臂围和肩周径,并计算术后臂围和肩周径与术前差值;应用疼痛视觉模拟量表(visual analogue scale,VAS)评估病人术前、术后24 h和48 h的疼痛情况;采用美国肩肘外科协会(American Society of Shoulder and Elbow Surgery,ASES)评分评估病人术后3个月和6个月肩关节功能恢复情况。结果观察组发生低体温5例(5%)及寒战2例(2%),明显低于对照组的11例(11%)和4例(4%)。观察组术后即刻、术后24 h与术前臂围及肩周径的差值较对照明显缩小,差异均有统计学意义(P均<0.05)。观察组术后24 h和48 h VAS评分较对照组改善明显,差异均有统计学意义(P均<0.05)。两组术后3个月和6个月ASES评分的差异均无统计学意义(P均>0.05)。结论肩关节镜手术中采用37℃恒温灌注液,能降低术中低体温及寒战的发生率,减轻病人术后关节肿胀和疼痛,有利于病人术后的快速康复,在临床中有推广价值。
基金Project (No. 2003CB716103) supported by the National Basic Research Program (973) of China
文摘A 3D ultrasound thermal model with a 3D finite element representation for modeling the thermal diffusion effects for hepatic ablation induced by spherical-section ultrasound phased array was developed. The model was first validated against available published measured data in rat liver. Using the validated model,effects of blood perfusion and heating schemes on lesion formation were studied for both single focus and split-focus intensity patterns. It was shown that for single focus sonication pattern the short-duration(～2 s) and high-intensity(～1250 W/cm2) heating scheme can completely reduce the cooling effect of the blood perfusion. The lesion shape and size were significantly altered by perfusion for split-focus pattern even with a rapid heating scheme when the focus spacing was larger than 2.4 mm. Underdosed areas might be present between two foci. Prolonging ex-posure time or shortening focus spacing can reduce the cool region between two foci. In addition,the influences of thermal and acoustic parameters were also studied. When the therapy depth is short(<5 cm) ,the lesion size monotonically increases with increasing attenuation coefficient that ranges from 5.4 to 11 Np/(m?MHz) .
文摘Objective To investigate whether the impairment of grafted livers after transplantation was induced by the same inflammatory cells both in cold and warm ischemia. Methods Male SD rats were divided into two groups at random,24 donor livers in each group were stored in Ringers solution at 4℃ for 120min or 240min of transplantation for blood sample and tissue specimen collection. Results Along with the prolongation of cold and warm ischemia time,the serum ALT,AST and LDH level increased gradually after transplantation.Under light microscopy,some hepatocytes presented necrosis after 3h and 6h of transplantation in cold ischemia,and neutrophilic infiltration in sinusoids were evident.Also,a large number of hepatocytes were necrotic 3h or 6h after transplantation in warm ischemia from NHBDs,and lymphocytic infiltration was evident in the sinusoids.The findings in electron microscopy was as the same as those of light microscopy,and the cells which infiltrated the sinusoids in warm ischemia were identified as T lymphocytes. Conclusion The impairment of grafted livers after transplantation appeared to be induced by two different kinds of inflammatory cells in cold and warm ischemia,that is,neutrophils mediated the cold ischemia-reperfusion,and T lymphocytes mediated the warm ischemia-reperfusion from NHBDs,but these findings are to be comfirmed in further investigations.
基金supported by a national Natural Science Foundation awarded project (81173346):Research of biological efficacy and mechanism on different techniques of scraping therapy
文摘Objective: To study the mechanism and effects of different scraping techniques on body surface blood perfusion volume and local skin temperature of healthy subjects and to provide a baseline for microcirculation and energy metabolism for the evaluation of the therapeutic effects of scraping. Methods: Changes of the local blood perfusion volume and skin temperature of healthy subjects before and after applying different scraping techniques were observed with a laser Doppler imager combined with an infrared thermographic device and the resulting data was analyzed with imaging and processing software for statistical analysis. Results: Local blood perfusion volume and skin temperature all increased after both reinforcing and reducing scraping techniques. The value of blood flow 60 and 90 min after the reducing technique was significantly higher than that after the reinforcing technique (P<0.01), while the skin temperature increased after both techniques but was not significantly different between the two (P>0.05). Conclusion: Scraping can significantly improve the local blood perfusion volume, increase skin temperature and promote local blood circulation and metabolism of tissues.
文摘Blinking is regarded as the continuous interrupted eyelid closure or opening and its thermal effect will compromise between these two. During a blink, the heat loss via convection, radiation and tear evaporation from cornea is prevented, warm tear is lay- ered across corneal surface and the vessels of the palpebral conjunctiva provide heat to anterior eye. In most of the thermal models in human eye that are found in literatures, effect of blinking is not included, simulation is carried out only in open eye. Thus, in this paper, thermal effects of blinking are investigated using one-dimensional finite element method in transient state case. The bio-heat transfer process is simulated during different blinking rates, lid closure and opening. The simulation is carried out using normal and extreme values of ambient temperatures, blood temperatures, evaporation rates, blood perfusion rates, and lens thermal conduetivities. Blinking is found to increase corneal and lens temperature by 1.29℃ and 0.78℃ respectively when compared to open eye. The results obtained from this model are useful in predicting temperature distribution in different laser eye surgeries, hyperthermia and cryosurgery treatment of eyelid carci- noma, choroidal melanoma and can be used for diagnosing temperature-related diseases.
