Two-mode circular states,which are superposition states from some two-mode coherent states,are studiedtheoretically.It is shown that under certain conditions two-mode circular states may exhibit nonclassical effects,s...Two-mode circular states,which are superposition states from some two-mode coherent states,are studiedtheoretically.It is shown that under certain conditions two-mode circular states may exhibit nonclassical effects,suchas sub-Poissonian statistics and intermode correlation.We propose schemes to generate two-mode circular states by theinteraction of a trapped ion with traveling wave lasers.展开更多
An analysis of historical data of Fitzroy River, which lies in the east coast of Australia, reveals that there is an increasing trend in extreme floods and droughts apparently attributable to increased variability of ...An analysis of historical data of Fitzroy River, which lies in the east coast of Australia, reveals that there is an increasing trend in extreme floods and droughts apparently attributable to increased variability of blue and green waters which could be due to climate change. In order to get a better understanding of the impacts of climate change on the water resources of the study area for near future as well as distant future, SWAT （soil and water assessment tool） model was applied. The model is first tested for its suitability in capturing the basin characteristics with available data, and then, forecasts from six GCMs （general circulation model） with about half-a-century lead time to 2046-2064 and about one-century lead time to 2080-2100 are incorporated to evaluate the impacts of climate change under three marker emission scenarios： A2, A1B and B 1. The results showed worsening water resources regime into the future.展开更多
Objective: This study aimed to investigate DNA sequences that are substantially homologous to the corresponding RNA sequence sections of the hepatitis C virus (HCV). These DNA sequences are present in the whole DNA ex...Objective: This study aimed to investigate DNA sequences that are substantially homologous to the corresponding RNA sequence sections of the hepatitis C virus (HCV). These DNA sequences are present in the whole DNA extracted from peripheral blood mononuclear cells (PBMCs) of HCV-negative subjects. We presumed that these experimentally proven 5'-noncoding region (5'-NCR) homologous DNA sequences could be contained in the extrachromosomal circular DNA (eccDNA) fraction as part of the whole cellular DNA. Methods: Home-made polymerase chain reaction (PCR) with whole cellular and isolated eccDNA, nucleotide basic local alignment search tool (BLASTn) alignments, and tests for patterns of methylation in selected sequence sections were performed. Results: The PCR tests revealed DNA sequences of up to 320 bp that broadly matched the corresponding sequence sections of known HCV genotypes. In contrast, BLASTn alignment searches of published HCV 5'-NCR sequences with human genome databases revealed only sequence segments of up to 36 bp of the 5'-NCR. The composition of these sequences shows missing base pairs, base pair mismatches as well as complete homology with HCV reference sequences. These short sequence sections are present in numerous copies on both the same and different chromosomes. The selected sequence region within the DNA sequences of the 5'-NCR revealed a broad diversity of individual patterns of methylation. Conclusions: The experimental results confirm our assumption that parts of the HCV 5'-NCR genomic RNA sequences are present at the DNA level in the eccDNA fraction of PBMCs. The tests for methylation patterns therein revealed individual methylomes which could represent an epigenetic feature. The respective sequence section might be subject to genetic regulation.展开更多
基金supported by the Natural Science Foundation of the Education Committee of Anhui Province of China under Grant No.JK2008A029
文摘Two-mode circular states,which are superposition states from some two-mode coherent states,are studiedtheoretically.It is shown that under certain conditions two-mode circular states may exhibit nonclassical effects,suchas sub-Poissonian statistics and intermode correlation.We propose schemes to generate two-mode circular states by theinteraction of a trapped ion with traveling wave lasers.
文摘An analysis of historical data of Fitzroy River, which lies in the east coast of Australia, reveals that there is an increasing trend in extreme floods and droughts apparently attributable to increased variability of blue and green waters which could be due to climate change. In order to get a better understanding of the impacts of climate change on the water resources of the study area for near future as well as distant future, SWAT （soil and water assessment tool） model was applied. The model is first tested for its suitability in capturing the basin characteristics with available data, and then, forecasts from six GCMs （general circulation model） with about half-a-century lead time to 2046-2064 and about one-century lead time to 2080-2100 are incorporated to evaluate the impacts of climate change under three marker emission scenarios： A2, A1B and B 1. The results showed worsening water resources regime into the future.
基金Project supported by the Exchange Scholarship Programs of the Landesregierung Schleswig-Holstein,Germany,for Jian-er WO
文摘Objective: This study aimed to investigate DNA sequences that are substantially homologous to the corresponding RNA sequence sections of the hepatitis C virus (HCV). These DNA sequences are present in the whole DNA extracted from peripheral blood mononuclear cells (PBMCs) of HCV-negative subjects. We presumed that these experimentally proven 5'-noncoding region (5'-NCR) homologous DNA sequences could be contained in the extrachromosomal circular DNA (eccDNA) fraction as part of the whole cellular DNA. Methods: Home-made polymerase chain reaction (PCR) with whole cellular and isolated eccDNA, nucleotide basic local alignment search tool (BLASTn) alignments, and tests for patterns of methylation in selected sequence sections were performed. Results: The PCR tests revealed DNA sequences of up to 320 bp that broadly matched the corresponding sequence sections of known HCV genotypes. In contrast, BLASTn alignment searches of published HCV 5'-NCR sequences with human genome databases revealed only sequence segments of up to 36 bp of the 5'-NCR. The composition of these sequences shows missing base pairs, base pair mismatches as well as complete homology with HCV reference sequences. These short sequence sections are present in numerous copies on both the same and different chromosomes. The selected sequence region within the DNA sequences of the 5'-NCR revealed a broad diversity of individual patterns of methylation. Conclusions: The experimental results confirm our assumption that parts of the HCV 5'-NCR genomic RNA sequences are present at the DNA level in the eccDNA fraction of PBMCs. The tests for methylation patterns therein revealed individual methylomes which could represent an epigenetic feature. The respective sequence section might be subject to genetic regulation.
