早发性卵巢功能不全是指女性40岁之前出现的卵巢功能衰退,严重危害女性生育力。随着现代生活方式的转变,该病发病率逐年上升,且有年轻化趋势。益经汤是中医临床常用方剂,古往今来常用于治疗“年未老经水断”,即卵巢早衰。药理学研究表明...早发性卵巢功能不全是指女性40岁之前出现的卵巢功能衰退,严重危害女性生育力。随着现代生活方式的转变,该病发病率逐年上升,且有年轻化趋势。益经汤是中医临床常用方剂,古往今来常用于治疗“年未老经水断”,即卵巢早衰。药理学研究表明,益经汤通过多靶点、多层面抑制卵巢炎症反应,激活卵巢细胞生长代谢,改善实验室指标,能有效缓解临床症状、提高卵巢功能。本文从中医和西医角度分别探讨益经汤的作用机制,总结益经汤治疗早发性卵巢功能不全的研究进展。Premature ovarian insufficiency refers to the decline of ovarian function in women before the age of 40, which seriously endangers female fertility. With the transformation of modern lifestyles, the incidence of this disease has been increasing year by year, and there is a trend of younger onset. Yijing Decoction is a commonly used traditional Chinese medicine formula, which has been used for treating “menstruation cessation before old age”, that is, premature ovarian failure, since ancient times. Pharmacological studies have shown that Yijing Decoction can effectively alleviate clinical symptoms and improve ovarian function by inhibiting ovarian inflammatory responses through multiple targets and multiple levels, activating the growth and metabolism of normal ovarian cells, and improving laboratory indicators. This article discusses the mechanism of action of Yijing Decoction from both traditional Chinese medicine and Western medicine perspectives and summarizes the research progress of Yijing Decoction in the treatment of premature ovarian insufficiency.展开更多
卵巢储备功能下降(DOR)是现代女性常见疾病之一,因其发病率逐年上升,且“三胎”政策的开放促使部分女性更加重视生育能力,故而对该病的诊治更加重视。西医对该病常采取激素序贯疗法,治疗期有效,但停药后易复发且副作用较多;而中医从整...卵巢储备功能下降(DOR)是现代女性常见疾病之一,因其发病率逐年上升,且“三胎”政策的开放促使部分女性更加重视生育能力,故而对该病的诊治更加重视。西医对该病常采取激素序贯疗法,治疗期有效,但停药后易复发且副作用较多;而中医从整体观念、辨证论治出发,中药随证加减,副作用小、安全性相对较高、疗效显著,值得应用和推广。现代研究发现《傅青主女科》中“益经汤”对卵巢储备功能下降所致的月经不调、不孕症的治疗卓有成效,故本文主要探讨卵巢储备功能下降的病因病机、益经汤对DOR的作用原理,并附一案例加以佐证。Decreased ovarian reserve function (DOR) is one of the common diseases in modern women. Due to its incidence rate has increased year by year, and the opening of the “three child” policy has prompted some women to pay more attention to fertility, Therefore, the diagnosis and treatment of this disease are increasingly attracting people’s attention. Western medicine often adopts hormone sequential therapy for this disease, which is effective during the treatment period, but is prone to recurrence and more side effects after discontinuation of medication. Traditional Chinese Medicine starts from a holistic concept and differentiation of syndromes for treatment. Addition and subtraction of traditional Chinese medicine based on syndrome differentiation, with minimal side effects, relatively high safety, and significant therapeutic effects. It is worthy of application and promotion. Modern research has found that the “Yijing Decoction” in “Fu Qingzhu’s Medical Department for Women” is effective in treating menstrual disorders and infertility caused by decreased ovarian reserve function. Therefore, this article mainly explores the etiology and pathogenesis of decreased ovarian reserve function, as well as the principle of action of Yijing Decoction on DOR, and attaches a case to support it.展开更多
文摘早发性卵巢功能不全是指女性40岁之前出现的卵巢功能衰退,严重危害女性生育力。随着现代生活方式的转变,该病发病率逐年上升,且有年轻化趋势。益经汤是中医临床常用方剂,古往今来常用于治疗“年未老经水断”,即卵巢早衰。药理学研究表明,益经汤通过多靶点、多层面抑制卵巢炎症反应,激活卵巢细胞生长代谢,改善实验室指标,能有效缓解临床症状、提高卵巢功能。本文从中医和西医角度分别探讨益经汤的作用机制,总结益经汤治疗早发性卵巢功能不全的研究进展。Premature ovarian insufficiency refers to the decline of ovarian function in women before the age of 40, which seriously endangers female fertility. With the transformation of modern lifestyles, the incidence of this disease has been increasing year by year, and there is a trend of younger onset. Yijing Decoction is a commonly used traditional Chinese medicine formula, which has been used for treating “menstruation cessation before old age”, that is, premature ovarian failure, since ancient times. Pharmacological studies have shown that Yijing Decoction can effectively alleviate clinical symptoms and improve ovarian function by inhibiting ovarian inflammatory responses through multiple targets and multiple levels, activating the growth and metabolism of normal ovarian cells, and improving laboratory indicators. This article discusses the mechanism of action of Yijing Decoction from both traditional Chinese medicine and Western medicine perspectives and summarizes the research progress of Yijing Decoction in the treatment of premature ovarian insufficiency.
文摘卵巢储备功能下降(DOR)是现代女性常见疾病之一,因其发病率逐年上升,且“三胎”政策的开放促使部分女性更加重视生育能力,故而对该病的诊治更加重视。西医对该病常采取激素序贯疗法,治疗期有效,但停药后易复发且副作用较多;而中医从整体观念、辨证论治出发,中药随证加减,副作用小、安全性相对较高、疗效显著,值得应用和推广。现代研究发现《傅青主女科》中“益经汤”对卵巢储备功能下降所致的月经不调、不孕症的治疗卓有成效,故本文主要探讨卵巢储备功能下降的病因病机、益经汤对DOR的作用原理,并附一案例加以佐证。Decreased ovarian reserve function (DOR) is one of the common diseases in modern women. Due to its incidence rate has increased year by year, and the opening of the “three child” policy has prompted some women to pay more attention to fertility, Therefore, the diagnosis and treatment of this disease are increasingly attracting people’s attention. Western medicine often adopts hormone sequential therapy for this disease, which is effective during the treatment period, but is prone to recurrence and more side effects after discontinuation of medication. Traditional Chinese Medicine starts from a holistic concept and differentiation of syndromes for treatment. Addition and subtraction of traditional Chinese medicine based on syndrome differentiation, with minimal side effects, relatively high safety, and significant therapeutic effects. It is worthy of application and promotion. Modern research has found that the “Yijing Decoction” in “Fu Qingzhu’s Medical Department for Women” is effective in treating menstrual disorders and infertility caused by decreased ovarian reserve function. Therefore, this article mainly explores the etiology and pathogenesis of decreased ovarian reserve function, as well as the principle of action of Yijing Decoction on DOR, and attaches a case to support it.
