Effect of active components group of Xiaoxuming decoction on cerebral mitophagy after focal cerebral ischemia/reperfusion injury,OBJECTIVE To explore the effect of the active components group of Xiaoxuming decoction(X...Effect of active components group of Xiaoxuming decoction on cerebral mitophagy after focal cerebral ischemia/reperfusion injury,OBJECTIVE To explore the effect of the active components group of Xiaoxuming decoction(XXMD)on mitophagy after cerebral ischemia/reperfusion(I/R)in MCAO rats.METHODS Male Sprague-Dawley rats were randomly divided into 4 groups:sham group,XXMD and rapamycin group.The I/R models were induced by middle cerebral artery occlusion.The effects of XXMD and rapamycin on behavioral study of focal cerebral I/R in rats were measured by Zea-Longa′s level standard scoring method and neurological defect score(m NSS).展开更多
文摘Effect of active components group of Xiaoxuming decoction on cerebral mitophagy after focal cerebral ischemia/reperfusion injury,OBJECTIVE To explore the effect of the active components group of Xiaoxuming decoction(XXMD)on mitophagy after cerebral ischemia/reperfusion(I/R)in MCAO rats.METHODS Male Sprague-Dawley rats were randomly divided into 4 groups:sham group,XXMD and rapamycin group.The I/R models were induced by middle cerebral artery occlusion.The effects of XXMD and rapamycin on behavioral study of focal cerebral I/R in rats were measured by Zea-Longa′s level standard scoring method and neurological defect score(m NSS).
