清洁环保的燃料电池混合动力有轨电车近年来受到极大关注,其高效的能量管理方法对混合动力系统性能起到至关重要的作用。传统等效氢耗最小化方法的荷电状态(state of charge,SOC)平衡系数通常采用恒定值,而有轨电车在大功率峰值需求和...清洁环保的燃料电池混合动力有轨电车近年来受到极大关注,其高效的能量管理方法对混合动力系统性能起到至关重要的作用。传统等效氢耗最小化方法的荷电状态(state of charge,SOC)平衡系数通常采用恒定值,而有轨电车在大功率峰值需求和减速制动过程中,恒定的SOC平衡系数不能满足瞬时等效氢耗最小的指标要求,并且在未知有轨电车工况条件下最优SOC平衡系数无法确定。针对上述问题,建立基于燃料电池/锂电池的混合动力有轨电车动力系统模型,并通过分析SOC平衡系数与氢耗特性,提出一种基于运行模式和动态混合度的等效氢耗最小化能量管理控制方法。该方法通过划分有轨电车运行模式,分析不同运行模式下SOC平衡系数与瞬时氢耗的关系,在此基础上提出基于运行模式和动态混合度的等效氢耗瞬时优化方法。结合有轨电车典型工况,搭建RT-LAB实时仿真平台,开展有轨电车能量管理系统实时仿真,并与传统等效氢耗最小化方法进行对比分析。结果表明,所提出的能量管理方法能够根据有轨电车工况的实时变化而自动分配需求功率,并在不同初始SOC的情况下,满足等效氢耗量最小的性能指标要求,提高整车燃料经济性。展开更多
为了提高轨道交通用燃料电池混合动力系统的燃料经济性并有效保持储能单元的荷电状态(state of charge,SOC),该文提出一种适用于燃料电池/超级电容混合动力系统的瞬时等效最小氢耗硬件在环方法。该方法采用超级电容的一阶RC等效电路模型...为了提高轨道交通用燃料电池混合动力系统的燃料经济性并有效保持储能单元的荷电状态(state of charge,SOC),该文提出一种适用于燃料电池/超级电容混合动力系统的瞬时等效最小氢耗硬件在环方法。该方法采用超级电容的一阶RC等效电路模型,建立超级电容的等效氢耗模型,通过推导得到超级电容最优输出的功率,根据当前SOC下超级电容最优输出功率并结合需求功率控制燃料电池系统的输出。通过在搭建的RT-LAB半实物硬件在环平台下,与功率跟随方法进行对比分析。结果表明,提出的方法能够有效减少氢气消耗量和保持超级电容SOC,将在轨道交通混合动力车辆大功率应用中具有良好的应用前景。展开更多
Aim To evaluate the bioequivalence of two brands of losartan/hydrochlorothiazide （50 mg/12.5 mg） compound tablets in healthy Chinese male volunteers. Methods An open, randomized, single-dose, two-period cross-over s...Aim To evaluate the bioequivalence of two brands of losartan/hydrochlorothiazide （50 mg/12.5 mg） compound tablets in healthy Chinese male volunteers. Methods An open, randomized, single-dose, two-period cross-over study with a wash-out period of 7 d was conducted. Twenty healthy male volunteers were given a single dose 50 mg losartan/12.5 mg hydrochlorothiazide of either test （T） or reference （R） compound tablets, respectively. Blood samples were collected up to 48 h after oral administration. The concentrations of losartan and hydrochlorothiazide in plasma were determined by a validated HPLC-ESI-MS method. Results In the case of losartan, the 90% confidence intervals of two one-side test for percent ratios with a significant level （α） of 0. 05 were 86% - 112% for AUC0-12 and 89% - 134% for Cmax, respectively, which were within the interval proposed in the Chinese Pharmacopoeia, 80% - 125% of AUC and 70% - 143% of Cmax, respectively. Similarly, the 90% confidence intervals for percent ratios were 85% - 100% and 75% - 102% for hydrochlorothiazide, both of which fell into the accepted interval. Conclusion Two immediate-release compound tablets of losartan/hydrochlorothiazide are bioequivalent from a statistical standpoint in the extent and rate of absorption from the single-dose study in healthy Chinese male volunteers.展开更多
文摘清洁环保的燃料电池混合动力有轨电车近年来受到极大关注,其高效的能量管理方法对混合动力系统性能起到至关重要的作用。传统等效氢耗最小化方法的荷电状态(state of charge,SOC)平衡系数通常采用恒定值,而有轨电车在大功率峰值需求和减速制动过程中,恒定的SOC平衡系数不能满足瞬时等效氢耗最小的指标要求,并且在未知有轨电车工况条件下最优SOC平衡系数无法确定。针对上述问题,建立基于燃料电池/锂电池的混合动力有轨电车动力系统模型,并通过分析SOC平衡系数与氢耗特性,提出一种基于运行模式和动态混合度的等效氢耗最小化能量管理控制方法。该方法通过划分有轨电车运行模式,分析不同运行模式下SOC平衡系数与瞬时氢耗的关系,在此基础上提出基于运行模式和动态混合度的等效氢耗瞬时优化方法。结合有轨电车典型工况,搭建RT-LAB实时仿真平台,开展有轨电车能量管理系统实时仿真,并与传统等效氢耗最小化方法进行对比分析。结果表明,所提出的能量管理方法能够根据有轨电车工况的实时变化而自动分配需求功率,并在不同初始SOC的情况下,满足等效氢耗量最小的性能指标要求,提高整车燃料经济性。
文摘为了提高轨道交通用燃料电池混合动力系统的燃料经济性并有效保持储能单元的荷电状态(state of charge,SOC),该文提出一种适用于燃料电池/超级电容混合动力系统的瞬时等效最小氢耗硬件在环方法。该方法采用超级电容的一阶RC等效电路模型,建立超级电容的等效氢耗模型,通过推导得到超级电容最优输出的功率,根据当前SOC下超级电容最优输出功率并结合需求功率控制燃料电池系统的输出。通过在搭建的RT-LAB半实物硬件在环平台下,与功率跟随方法进行对比分析。结果表明,提出的方法能够有效减少氢气消耗量和保持超级电容SOC,将在轨道交通混合动力车辆大功率应用中具有良好的应用前景。
文摘Aim To evaluate the bioequivalence of two brands of losartan/hydrochlorothiazide （50 mg/12.5 mg） compound tablets in healthy Chinese male volunteers. Methods An open, randomized, single-dose, two-period cross-over study with a wash-out period of 7 d was conducted. Twenty healthy male volunteers were given a single dose 50 mg losartan/12.5 mg hydrochlorothiazide of either test （T） or reference （R） compound tablets, respectively. Blood samples were collected up to 48 h after oral administration. The concentrations of losartan and hydrochlorothiazide in plasma were determined by a validated HPLC-ESI-MS method. Results In the case of losartan, the 90% confidence intervals of two one-side test for percent ratios with a significant level （α） of 0. 05 were 86% - 112% for AUC0-12 and 89% - 134% for Cmax, respectively, which were within the interval proposed in the Chinese Pharmacopoeia, 80% - 125% of AUC and 70% - 143% of Cmax, respectively. Similarly, the 90% confidence intervals for percent ratios were 85% - 100% and 75% - 102% for hydrochlorothiazide, both of which fell into the accepted interval. Conclusion Two immediate-release compound tablets of losartan/hydrochlorothiazide are bioequivalent from a statistical standpoint in the extent and rate of absorption from the single-dose study in healthy Chinese male volunteers.
