Background Propolis, a natural product produced by the honeybee, has been used for thousands of years in folk medicine for several purposes. The extract contains amino acids, phenolic acids, phenolic acid esters, flav...Background Propolis, a natural product produced by the honeybee, has been used for thousands of years in folk medicine for several purposes. The extract contains amino acids, phenolic acids, phenolic acid esters, flavonoids, cinnamic acid, terpenes and caffeic acid. It has many effects such as antiinflammatory, immunostimulatory, antiviral and antibacterial, and so on. The exact mode of physiological or biochemical mechanisms responsible for the medical effects, however, is yet to be determined. The pharmacologically active molecules in the propolis are flavonoids and phenolic acids and their esters. The flavonoids are used by botanists for taxonomical classification. They regulate plant growth by induction of gene expression, and they influence other biological cells in numerous ways. Flavonoids inhibit or kill many bacterial strains, inhibit important viral enzymes, such as reverse transcriptase and protease, and destroy some pathogenic protozoans. There is considerable evidence suggesting that flavonoids have wide therapeutical effects to the diseases of cardiovascular system. According to our results, flavonoids extracted from propolis have been proven that it could ameliorate the cardiovascular disease. Ischemia-reperfusion injury (IRI) has been observed in many clinical cases, especially after angioplasty, ischemia, after thrombolysis, and after cardiopulmonary bypass.展开更多
文摘Background Propolis, a natural product produced by the honeybee, has been used for thousands of years in folk medicine for several purposes. The extract contains amino acids, phenolic acids, phenolic acid esters, flavonoids, cinnamic acid, terpenes and caffeic acid. It has many effects such as antiinflammatory, immunostimulatory, antiviral and antibacterial, and so on. The exact mode of physiological or biochemical mechanisms responsible for the medical effects, however, is yet to be determined. The pharmacologically active molecules in the propolis are flavonoids and phenolic acids and their esters. The flavonoids are used by botanists for taxonomical classification. They regulate plant growth by induction of gene expression, and they influence other biological cells in numerous ways. Flavonoids inhibit or kill many bacterial strains, inhibit important viral enzymes, such as reverse transcriptase and protease, and destroy some pathogenic protozoans. There is considerable evidence suggesting that flavonoids have wide therapeutical effects to the diseases of cardiovascular system. According to our results, flavonoids extracted from propolis have been proven that it could ameliorate the cardiovascular disease. Ischemia-reperfusion injury (IRI) has been observed in many clinical cases, especially after angioplasty, ischemia, after thrombolysis, and after cardiopulmonary bypass.
