膝关节置换术后假体周围感染是膝关节置换术后最严重的并发症之一,不仅严重影响患者生活质量、增加患者负担,也给医师造成一定的影响。随着对该疾病的研究,临床上的治疗方案也越来越多,目前常见的治疗方案有保守治疗(如单纯抗生素治疗...膝关节置换术后假体周围感染是膝关节置换术后最严重的并发症之一,不仅严重影响患者生活质量、增加患者负担,也给医师造成一定的影响。随着对该疾病的研究,临床上的治疗方案也越来越多,目前常见的治疗方案有保守治疗(如单纯抗生素治疗、中医药治疗)、手术治疗等,本文对当前膝关节置换术后假体周围感染的中西医治疗进行综述,为临床研究和临床治疗提供一定的参考。According Periprosthetic joint infection after knee replacement is one of the most serious complications after knee replacement surgery, not only seriously affecting the quality of life of patients and increasing the burden of patients, but also causing certain impact on doctors. With the research on this disease, the clinical treatment schemes have become more and more, and the common treatment schemes at present include conservative treatment (such as simple antibiotic treatment, Chinese medicine treatment), surgical treatment, etc. This paper reviews the current Chinese and Western medicine treatment of periprosthetic joint infection after knee replacement surgery, providing certain reference for clinical research and clinical treatment.展开更多
目的探究中枢敏化(central sensitization,CS)与全膝关节置换术(total knee arthroplasty,TKA)术后西安大略和麦克马斯特大学(the Western Ontario and McMaster Universities,WOMAC)骨关节炎指数之间的关系。方法这项前瞻性研究纳入了2...目的探究中枢敏化(central sensitization,CS)与全膝关节置换术(total knee arthroplasty,TKA)术后西安大略和麦克马斯特大学(the Western Ontario and McMaster Universities,WOMAC)骨关节炎指数之间的关系。方法这项前瞻性研究纳入了2022年2月至2023年2月在西安交通大学附属红会医院接受初次单侧TKA的180例患者,男53例,女127例;年龄50~79岁,平均(64.8±5.9)岁。使用中枢敏化量表(central sensitization inventory,CSI)的A部分来评估术前CS。评估术前CSI与术后1年WOMAC评分之间的相关性,以及术后WOMAC评分与术前CSI严重程度之间的关联。此外,还评估了不同CSI严重程度与WOMAC评分各维度之间的关系。结果29例患者(16.1%)在术前有CS,术前CSI与术后WOMAC评分呈正相关(r=0.607,P<0.001)。术前CSI严重程度为中度或更高的患者,术后WOMAC评分显著高于术前CSI严重程度为亚临床或轻度的患者(P<0.001)。与亚临床组相比,中度或更高CSI严重程度的WOMAC评分各个维度得分显著较高(P<0.001)。结论术前CSI与TKA术后1年WOMAC评分呈显著正相关,对术前CS患者进行干预有助于改善TKA后的临床效果。展开更多
文摘膝关节置换术后假体周围感染是膝关节置换术后最严重的并发症之一,不仅严重影响患者生活质量、增加患者负担,也给医师造成一定的影响。随着对该疾病的研究,临床上的治疗方案也越来越多,目前常见的治疗方案有保守治疗(如单纯抗生素治疗、中医药治疗)、手术治疗等,本文对当前膝关节置换术后假体周围感染的中西医治疗进行综述,为临床研究和临床治疗提供一定的参考。According Periprosthetic joint infection after knee replacement is one of the most serious complications after knee replacement surgery, not only seriously affecting the quality of life of patients and increasing the burden of patients, but also causing certain impact on doctors. With the research on this disease, the clinical treatment schemes have become more and more, and the common treatment schemes at present include conservative treatment (such as simple antibiotic treatment, Chinese medicine treatment), surgical treatment, etc. This paper reviews the current Chinese and Western medicine treatment of periprosthetic joint infection after knee replacement surgery, providing certain reference for clinical research and clinical treatment.
