Phytochemical constituents of the shoots and roots extract of chosen eight medicinal plants （Plantago major, Verbesina encelioides, Glinus lotoides, Helotropium supinum, Mentha microphylla, Euphorbia hirta, Juncus su...Phytochemical constituents of the shoots and roots extract of chosen eight medicinal plants （Plantago major, Verbesina encelioides, Glinus lotoides, Helotropium supinum, Mentha microphylla, Euphorbia hirta, Juncus subulatus and Convolvulus arvensis） were estimated using standard qualitative analysis. The extract contained alkaloids, glycosides, saponins, phenols, tannins, f[avonoids and terpenoids in some medicinal plants while others contain some only of these phytochemical components. Allelopathic effect of the various concentrations of the extracts on the soil algal diversity was also investigated. Wollea saccata was the only algal species disappeared from all applied investigated plant extracts. Phormidium richardsii, Monoraphidium braunii, Eunotia verneris and Nitzschia bilobata were the highly sensitive algal species to all applied shoot and root extract from all tested plants, they disappeared from most of the studied plants. On the other hand, Phormidium animale and Chlorella neustonice were highly tolerant algal species to all applied extracts. Counts of Cyanophyceae, Chlorophyceae and Bacillariophyceae were decreased by addition of some investigated medicinal plants extracts such as Juncus subulatus, Convolvulus arvensis and Euphorbia hirta. So the authors can use these plants extracts in biocontrol of the nuisance of algal bloom or any other microorganisms. Also, these plants may be useful to recover eutrophic water which needs further investigation.展开更多
Six indigenous folk medicinal plants growing wild in the area of Tabuk, Saudi Arabia which were selected for the study of their phytochemistry as well as their biological activities as antitumor and antifolate agents....Six indigenous folk medicinal plants growing wild in the area of Tabuk, Saudi Arabia which were selected for the study of their phytochemistry as well as their biological activities as antitumor and antifolate agents. Antitumor activities of methanol extracts of the six plants were measured in vitro using three human tumor cell lines （breast, lung and CNS cancers） while antifolate activities were assessed using commercial dihyrofolate reductase obtained from Sigma Co. Among the six plant extracts tested, the most remarkable were those of Caralluma sinaica and Fagonia tenuifolia. Caralluma extract showed strong antitumor activity （low GIso） against the three human tumor cell lines. Fagonia extract, on the other hand, was quite inhibitory to the growth of CNS cancer and breast cancer cell lines but much less so against lung cancer cells. Extracts of both Sonchus oleraceus and Caralluma sinaica were strongly inhibitory to DHFR. These results suggest that the mechanism of anticancer activity of Caralluma plant is through DHFR inhibition but that of Fagonia may follow a different path.展开更多
The aim of the study was to investigate the vibriocidal activity of crude extracts of 18 ethnomedicinal plants used by Nicobarese tribe. Plants were collected from the villages of Car Nicobar Island with the help of T...The aim of the study was to investigate the vibriocidal activity of crude extracts of 18 ethnomedicinal plants used by Nicobarese tribe. Plants were collected from the villages of Car Nicobar Island with the help of TKPs （traditional knowledge practitioners）. The methanol extracts were obtained by cold percolation method and the antimicrobial activity of the extracts was observed by agar well diffusion method. Results indicated that out of 18 plants, seven plants exhibited vibriocidal activity. Morinda citrifolia, Ganophyllumfalcatum and Leea aequata were most active among the plants tested. This study thus can be further utilized to formulate the new antimicrobial agents to fight against Vibrio cholerae.展开更多
OBJECTIVE: To report some of the pharmacological features of the medicinal plant Ocimum basilicum.METHODS: In the current studies, Antifungal activity of crude methanolic fraction of Ocimum basilicum was determined ag...OBJECTIVE: To report some of the pharmacological features of the medicinal plant Ocimum basilicum.METHODS: In the current studies, Antifungal activity of crude methanolic fraction of Ocimum basilicum was determined against eight pathogenic fungal strains using tube dilution assay. The methanolic fraction was also investigated for phytotoxic and hemagglutination activity.RESULTS: Of the eight strains investigated only Candida albicans and Curvilaria lunata were found to be least affected by plant extract while the rest were significantly inhibited. Moderate phytotoxic activity was observed against lemna minor. Hemagglutination activity showed absence of phytolectins and hence no agglutination of erythrocytes.CONCLUSION: The crude extract of Ocimum basilicum has significant properties against fungi and phytotoxic substances.展开更多
文摘Phytochemical constituents of the shoots and roots extract of chosen eight medicinal plants （Plantago major, Verbesina encelioides, Glinus lotoides, Helotropium supinum, Mentha microphylla, Euphorbia hirta, Juncus subulatus and Convolvulus arvensis） were estimated using standard qualitative analysis. The extract contained alkaloids, glycosides, saponins, phenols, tannins, f[avonoids and terpenoids in some medicinal plants while others contain some only of these phytochemical components. Allelopathic effect of the various concentrations of the extracts on the soil algal diversity was also investigated. Wollea saccata was the only algal species disappeared from all applied investigated plant extracts. Phormidium richardsii, Monoraphidium braunii, Eunotia verneris and Nitzschia bilobata were the highly sensitive algal species to all applied shoot and root extract from all tested plants, they disappeared from most of the studied plants. On the other hand, Phormidium animale and Chlorella neustonice were highly tolerant algal species to all applied extracts. Counts of Cyanophyceae, Chlorophyceae and Bacillariophyceae were decreased by addition of some investigated medicinal plants extracts such as Juncus subulatus, Convolvulus arvensis and Euphorbia hirta. So the authors can use these plants extracts in biocontrol of the nuisance of algal bloom or any other microorganisms. Also, these plants may be useful to recover eutrophic water which needs further investigation.
文摘Six indigenous folk medicinal plants growing wild in the area of Tabuk, Saudi Arabia which were selected for the study of their phytochemistry as well as their biological activities as antitumor and antifolate agents. Antitumor activities of methanol extracts of the six plants were measured in vitro using three human tumor cell lines （breast, lung and CNS cancers） while antifolate activities were assessed using commercial dihyrofolate reductase obtained from Sigma Co. Among the six plant extracts tested, the most remarkable were those of Caralluma sinaica and Fagonia tenuifolia. Caralluma extract showed strong antitumor activity （low GIso） against the three human tumor cell lines. Fagonia extract, on the other hand, was quite inhibitory to the growth of CNS cancer and breast cancer cell lines but much less so against lung cancer cells. Extracts of both Sonchus oleraceus and Caralluma sinaica were strongly inhibitory to DHFR. These results suggest that the mechanism of anticancer activity of Caralluma plant is through DHFR inhibition but that of Fagonia may follow a different path.
文摘The aim of the study was to investigate the vibriocidal activity of crude extracts of 18 ethnomedicinal plants used by Nicobarese tribe. Plants were collected from the villages of Car Nicobar Island with the help of TKPs （traditional knowledge practitioners）. The methanol extracts were obtained by cold percolation method and the antimicrobial activity of the extracts was observed by agar well diffusion method. Results indicated that out of 18 plants, seven plants exhibited vibriocidal activity. Morinda citrifolia, Ganophyllumfalcatum and Leea aequata were most active among the plants tested. This study thus can be further utilized to formulate the new antimicrobial agents to fight against Vibrio cholerae.
基金Supported by University of Peshawar(Bio-activities of methanolic extracts of Ocimum basilicum)
文摘OBJECTIVE: To report some of the pharmacological features of the medicinal plant Ocimum basilicum.METHODS: In the current studies, Antifungal activity of crude methanolic fraction of Ocimum basilicum was determined against eight pathogenic fungal strains using tube dilution assay. The methanolic fraction was also investigated for phytotoxic and hemagglutination activity.RESULTS: Of the eight strains investigated only Candida albicans and Curvilaria lunata were found to be least affected by plant extract while the rest were significantly inhibited. Moderate phytotoxic activity was observed against lemna minor. Hemagglutination activity showed absence of phytolectins and hence no agglutination of erythrocytes.CONCLUSION: The crude extract of Ocimum basilicum has significant properties against fungi and phytotoxic substances.
