Acupuncture dose-effect relationship is the essential feature of acupuncture and the key factor of acupuncture’s therapeutic effect.It is a comprehensive category,including needle direction,needle strength,needle dep...Acupuncture dose-effect relationship is the essential feature of acupuncture and the key factor of acupuncture’s therapeutic effect.It is a comprehensive category,including needle direction,needle strength,needle depth,selection of specific techniques,length of time between acupuncture treatment sessions,length of needle retention time,and frequency of treatment,all of which play a decisive role in the curative effect and prognosis of diseases[1].展开更多
Acupuncture therapy is widely used in the clinic,and its therapeutic effects have been proven by numerous studies.The dose–effect relationship of acupuncture is a fundamental aspect of the acupuncture research system...Acupuncture therapy is widely used in the clinic,and its therapeutic effects have been proven by numerous studies.The dose–effect relationship of acupuncture is a fundamental aspect of the acupuncture research system.Recent studies found that different acupuncture dosages altered study results directly,indicating the importance of screening the optimal stimulation dosage.However,the system for studying the acupuncture dose–effect relationship is still in its infancy,and the methodology of the system needs to be improved.This review aimed to define the factors impacting acupuncture“dosage”and“effect,”and to improve the methodological system for research on the dose–effect relationship of acupuncture.By summarizing the current findings of acupuncture dose–effect studies,we discussed the vital acupuncture parameters and methodological problems that influence the relationship between acupuncture dosage and its effects.These factors consist of specific influencing factors(acupoint selection,acupuncture manipulation parameters,de qi response)and nonspecific influencing factors(comparison selection,blinding procedure,patient expectancy).Our perspectives offer suggestions for the design of acupuncture dosage–effect trials.Further studies need to be conducted to establish the methodological system and provide systematic evidence of the acupuncture dose–effect relationship.展开更多
文摘Acupuncture dose-effect relationship is the essential feature of acupuncture and the key factor of acupuncture’s therapeutic effect.It is a comprehensive category,including needle direction,needle strength,needle depth,selection of specific techniques,length of time between acupuncture treatment sessions,length of needle retention time,and frequency of treatment,all of which play a decisive role in the curative effect and prognosis of diseases[1].
基金funded by the Ministry of Science and Technology of the People’s Republic of ChinaNational Key Research and Development Program(2010CB530506,2018YFC1706001,2019YFC0840709)+2 种基金Tianjin Municipal Science and Technology BureauTianjin Science and Technology Plan Project(18PTLCSY00060)the First Teaching Hospital of Tianjin University of Traditional Chinese Medicine,Exploration and Innovation Project(YB202112)
文摘Acupuncture therapy is widely used in the clinic,and its therapeutic effects have been proven by numerous studies.The dose–effect relationship of acupuncture is a fundamental aspect of the acupuncture research system.Recent studies found that different acupuncture dosages altered study results directly,indicating the importance of screening the optimal stimulation dosage.However,the system for studying the acupuncture dose–effect relationship is still in its infancy,and the methodology of the system needs to be improved.This review aimed to define the factors impacting acupuncture“dosage”and“effect,”and to improve the methodological system for research on the dose–effect relationship of acupuncture.By summarizing the current findings of acupuncture dose–effect studies,we discussed the vital acupuncture parameters and methodological problems that influence the relationship between acupuncture dosage and its effects.These factors consist of specific influencing factors(acupoint selection,acupuncture manipulation parameters,de qi response)and nonspecific influencing factors(comparison selection,blinding procedure,patient expectancy).Our perspectives offer suggestions for the design of acupuncture dosage–effect trials.Further studies need to be conducted to establish the methodological system and provide systematic evidence of the acupuncture dose–effect relationship.
