目的:应用颞侧球结膜眼红指数(TCHI)、眼部症状评分(OSS)及视觉模拟量表(VAS)研究翼状胬肉切除联合自体结膜移植术后患者眼表炎症反应变化情况,并将上述指标应用于抗炎治疗效果评价中,判断其应用有效性。方法:以100例翼状胬肉患者为研...目的:应用颞侧球结膜眼红指数(TCHI)、眼部症状评分(OSS)及视觉模拟量表(VAS)研究翼状胬肉切除联合自体结膜移植术后患者眼表炎症反应变化情况,并将上述指标应用于抗炎治疗效果评价中,判断其应用有效性。方法:以100例翼状胬肉患者为研究对象,均采取翼状胬肉切除联合自体结膜移植术治疗,术后对眼表炎症进行治疗。评估术前,术后1、3、7、10 d,术后1、2个月眼表炎症,应用眼表综合分析仪对TCHI做出评估,观察OSS、VAS评分等主观量化指标的动态变化,采用荧光素钠染色法对角膜上皮愈合情况进行观察,并测量最佳矫正视力(BCVA)。结果:患者术后2个月BCVA明显较术前低(P<0.05)。术后10 d患者角膜无荧光素染色出现,提示角膜上皮缺损愈合完全。术后1 d OSS评分及TCHI值高于术前(均P<0.05);随着抗炎治疗的开展,患者术后7 d OSS评分及TCHI值均降至术前水平(均P>0.05);患者术后1、2个月上述指标均较术前低(均P<0.05)。患者术后1 d VAS评分高于术前(P<0.05);随着抗炎治疗的开展,患者术后7 d VAS评分降至术前水平(P>0.05);术后2个月VAS评分较术前低(P<0.05)。结论:OSS、VAS评分及TCHI可对行翼状胬肉切除联合自体结膜移植术治疗患者的炎症状态做出有效评估,并可作为抗炎治疗有效性的评价指标。展开更多
Purpose: To analyse clinical referral diagnoses and the location of lesions wi th histologically verified lacrimal gland tissue occurring outside the fossa of the lacrimal gland. Methods: Sections of lesions excised f...Purpose: To analyse clinical referral diagnoses and the location of lesions wi th histologically verified lacrimal gland tissue occurring outside the fossa of the lacrimal gland. Methods: Sections of lesions excised from areas outside the fossa of the lacrimal gland containing lacrimal gland tissue on histological exa mination were collected from the files of the Eye Pathology Institute, Copenhage n, Denmark. Specimens spanned a period of 50 years. Sections were re-examined a nd referral data on location and clinical diagnosis were compared with histologi cal findings. Results: A total of 120 lesions were collected. Of these, 59 (49% ) consisted of prolapsed lacrimal gland. The remaining 61 (51%) lesions contain ed ectopic lacrimal gland tissue, either as part of a complex choristoma in 38 ( 32%) cases, or as solitary ectopic lacrimal gland tissue in 23 (19%) cases. Th e majority (97; 81%) of lesions had been located at the temporal epibulbar conj unctiva and included mainly prolapsed lacrimal gland and complex choristoma. The clinical referral diagnoses covered a wide spectrum of lesions. The most freque nt clinical diagnoses were non-specific tumour (35%), non-specific cyst (18% ) and dermoid (11%). Of the 61 lesions containing ectopic lacrimal gland tissue , only two had been preoperatively diagnosed as such and only two of the 59 lesi ons with prolapsed lacrimal gland had been correctly diagnosed. Conclusions: Pro lapsed palpebral lobe of the lacrimal gland was the most common lesion and, as e xpected, the prime location was the temporal conjunctiva. Despite this location, the referring clinical diagnosis was often wrong or non-specific. Surgeons see m to have been unaware of the various clinical manifestations of extrafossal gla ndular tissue, particularly when excising lesions in the upper temporal region o f the conjunctiva. Surgical intervention in this location may jeopardizethe excr etory ducts of the lacrimal gland and may consequently lead to dry eye and thus should be avoided when the typical clinical appearance of prolapsed lacrimal gla nd is encountered.展开更多
文摘目的:应用颞侧球结膜眼红指数(TCHI)、眼部症状评分(OSS)及视觉模拟量表(VAS)研究翼状胬肉切除联合自体结膜移植术后患者眼表炎症反应变化情况,并将上述指标应用于抗炎治疗效果评价中,判断其应用有效性。方法:以100例翼状胬肉患者为研究对象,均采取翼状胬肉切除联合自体结膜移植术治疗,术后对眼表炎症进行治疗。评估术前,术后1、3、7、10 d,术后1、2个月眼表炎症,应用眼表综合分析仪对TCHI做出评估,观察OSS、VAS评分等主观量化指标的动态变化,采用荧光素钠染色法对角膜上皮愈合情况进行观察,并测量最佳矫正视力(BCVA)。结果:患者术后2个月BCVA明显较术前低(P<0.05)。术后10 d患者角膜无荧光素染色出现,提示角膜上皮缺损愈合完全。术后1 d OSS评分及TCHI值高于术前(均P<0.05);随着抗炎治疗的开展,患者术后7 d OSS评分及TCHI值均降至术前水平(均P>0.05);患者术后1、2个月上述指标均较术前低(均P<0.05)。患者术后1 d VAS评分高于术前(P<0.05);随着抗炎治疗的开展,患者术后7 d VAS评分降至术前水平(P>0.05);术后2个月VAS评分较术前低(P<0.05)。结论:OSS、VAS评分及TCHI可对行翼状胬肉切除联合自体结膜移植术治疗患者的炎症状态做出有效评估,并可作为抗炎治疗有效性的评价指标。
文摘Purpose: To analyse clinical referral diagnoses and the location of lesions wi th histologically verified lacrimal gland tissue occurring outside the fossa of the lacrimal gland. Methods: Sections of lesions excised from areas outside the fossa of the lacrimal gland containing lacrimal gland tissue on histological exa mination were collected from the files of the Eye Pathology Institute, Copenhage n, Denmark. Specimens spanned a period of 50 years. Sections were re-examined a nd referral data on location and clinical diagnosis were compared with histologi cal findings. Results: A total of 120 lesions were collected. Of these, 59 (49% ) consisted of prolapsed lacrimal gland. The remaining 61 (51%) lesions contain ed ectopic lacrimal gland tissue, either as part of a complex choristoma in 38 ( 32%) cases, or as solitary ectopic lacrimal gland tissue in 23 (19%) cases. Th e majority (97; 81%) of lesions had been located at the temporal epibulbar conj unctiva and included mainly prolapsed lacrimal gland and complex choristoma. The clinical referral diagnoses covered a wide spectrum of lesions. The most freque nt clinical diagnoses were non-specific tumour (35%), non-specific cyst (18% ) and dermoid (11%). Of the 61 lesions containing ectopic lacrimal gland tissue , only two had been preoperatively diagnosed as such and only two of the 59 lesi ons with prolapsed lacrimal gland had been correctly diagnosed. Conclusions: Pro lapsed palpebral lobe of the lacrimal gland was the most common lesion and, as e xpected, the prime location was the temporal conjunctiva. Despite this location, the referring clinical diagnosis was often wrong or non-specific. Surgeons see m to have been unaware of the various clinical manifestations of extrafossal gla ndular tissue, particularly when excising lesions in the upper temporal region o f the conjunctiva. Surgical intervention in this location may jeopardizethe excr etory ducts of the lacrimal gland and may consequently lead to dry eye and thus should be avoided when the typical clinical appearance of prolapsed lacrimal gla nd is encountered.
