目的探讨容量保证的高频振荡通气(volume-guaranteed high frequency oscillation ventilation,HFOVVG)与常频机械通气(conventional mechanical ventilation,CMV)治疗早产儿呼吸衰竭的疗效差异。方法前瞻性纳入2018年10月—2022年12月...目的探讨容量保证的高频振荡通气(volume-guaranteed high frequency oscillation ventilation,HFOVVG)与常频机械通气(conventional mechanical ventilation,CMV)治疗早产儿呼吸衰竭的疗效差异。方法前瞻性纳入2018年10月—2022年12月东南大学医学院附属江阴医院新生儿科住院的112例呼吸衰竭早产儿(胎龄28~34周)为研究对象,采用掷硬币法基于机械通气模式随机分为HFOV-VG组(44例)和CMV组(68例),比较两种通气模式的治疗效果。结果HFOV-VG组和CMV组治疗24 h后动脉血pH、氧分压、二氧化碳分压及氧分压/吸入气氧浓度均较治疗前改善(P<0.05),且HFOV-VG组改善效果优于CMV组(P<0.05)。两组早产儿并发症、28 d病死率、住院时长比较差异无统计学意义(P>0.05),但HFOV-VG组有创机械通气时间短于CMV组(P<0.05)。随访至纠正6月龄,两组早产儿小儿神经心理发育量表的发育商、大运动、精细动作、适应能力、语言、社会行为得分差异无统计学意义(P>0.05)。结论HFOV-VG模式较CMV模式能够更快提高氧分压、促进二氧化碳排出,从而改善呼吸衰竭早产儿的氧合、缩短呼吸机使用时间,对患儿短期神经行为发育无显著影响。展开更多
Mooring observations were conducted from July 16, 2011 to March 30, 2012 east of Mindanao, Philippines （127°2.8＇E, 8°0.3＇N） to observe the abyssal current at about 5 600 m deep and 500 m above the ocean ...Mooring observations were conducted from July 16, 2011 to March 30, 2012 east of Mindanao, Philippines （127°2.8＇E, 8°0.3＇N） to observe the abyssal current at about 5 600 m deep and 500 m above the ocean bottom. Several features were revealed： 1） the observed abyssal current was highly variable with standard deviations of 57.3 mrn/s and 34.0 ram/s, larger than the mean values of-31.9 and 16.6 mm/s for the zonal and meridional components, respectively; 2） low-frequency current longer than 6 days exhibited strong seasonal variation, flowing southeastward （mean flow direction of 119.0° clockwise from north） before about October 1, 2011 and northwestward （mean flow direction of 60.5° counter-clockwise from north） thereafter; 3） the high-frequency flow bands were dominated by tidal currents O1, K1, M2, and S2, and near-inertial currents, whose frequencies were higher than the local inertial frequency. The two diurnal tidal constituents were much stronger than the two semidiumal ones. This study provides for the first time an observational insight into the abyssal western boundary current east of Mindanao based on long-term observations at one site. It is meaningful for further research into the deep and abyssal circulation over the whole Philippine Sea and the 3D structure of the westem boundary current system in this region. More observational and high-resolution model studies are needed to examine the spatial structure and temporal variation of the abyssal current over a much larger space and longer period, their relation to the upper-layer circulation, and the underlying dynamics.展开更多
In order to enhance the efficiency of spectrum utilization and reduce communication overhead in spectrum sharing process, we propose a two-stage dynamic spectrum sharing scheme in which cooperative and noncooperative ...In order to enhance the efficiency of spectrum utilization and reduce communication overhead in spectrum sharing process, we propose a two-stage dynamic spectrum sharing scheme in which cooperative and noncooperative modes are analyzed in both stages. In particular, the existence and the uniqueness of Nash Equilibrium(NE) strategies for noncooperative mode are proved. In addition, a distributed iterative algorithm is proposed to obtain the optimal solutions of the scheme. Simulation studies are carried out to show the performance comparison between two modes as well as the system revenue improvement of the proposed scheme compared with a conventional scheme without a virtual price control factor.展开更多
文摘目的探讨容量保证的高频振荡通气(volume-guaranteed high frequency oscillation ventilation,HFOVVG)与常频机械通气(conventional mechanical ventilation,CMV)治疗早产儿呼吸衰竭的疗效差异。方法前瞻性纳入2018年10月—2022年12月东南大学医学院附属江阴医院新生儿科住院的112例呼吸衰竭早产儿(胎龄28~34周)为研究对象,采用掷硬币法基于机械通气模式随机分为HFOV-VG组(44例)和CMV组(68例),比较两种通气模式的治疗效果。结果HFOV-VG组和CMV组治疗24 h后动脉血pH、氧分压、二氧化碳分压及氧分压/吸入气氧浓度均较治疗前改善(P<0.05),且HFOV-VG组改善效果优于CMV组(P<0.05)。两组早产儿并发症、28 d病死率、住院时长比较差异无统计学意义(P>0.05),但HFOV-VG组有创机械通气时间短于CMV组(P<0.05)。随访至纠正6月龄,两组早产儿小儿神经心理发育量表的发育商、大运动、精细动作、适应能力、语言、社会行为得分差异无统计学意义(P>0.05)。结论HFOV-VG模式较CMV模式能够更快提高氧分压、促进二氧化碳排出,从而改善呼吸衰竭早产儿的氧合、缩短呼吸机使用时间,对患儿短期神经行为发育无显著影响。
基金Supported by the China Postdoctoral Science Foundation(No.2013M530331)the Project of State Strategic Program of Global Change(No.2013CB956202)
文摘Mooring observations were conducted from July 16, 2011 to March 30, 2012 east of Mindanao, Philippines （127°2.8＇E, 8°0.3＇N） to observe the abyssal current at about 5 600 m deep and 500 m above the ocean bottom. Several features were revealed： 1） the observed abyssal current was highly variable with standard deviations of 57.3 mrn/s and 34.0 ram/s, larger than the mean values of-31.9 and 16.6 mm/s for the zonal and meridional components, respectively; 2） low-frequency current longer than 6 days exhibited strong seasonal variation, flowing southeastward （mean flow direction of 119.0° clockwise from north） before about October 1, 2011 and northwestward （mean flow direction of 60.5° counter-clockwise from north） thereafter; 3） the high-frequency flow bands were dominated by tidal currents O1, K1, M2, and S2, and near-inertial currents, whose frequencies were higher than the local inertial frequency. The two diurnal tidal constituents were much stronger than the two semidiumal ones. This study provides for the first time an observational insight into the abyssal western boundary current east of Mindanao based on long-term observations at one site. It is meaningful for further research into the deep and abyssal circulation over the whole Philippine Sea and the 3D structure of the westem boundary current system in this region. More observational and high-resolution model studies are needed to examine the spatial structure and temporal variation of the abyssal current over a much larger space and longer period, their relation to the upper-layer circulation, and the underlying dynamics.
基金supported in part by the National Natural Science Foundation of China(61471115)the National Science and Technology Major Project of the Ministry of Science and Technology of China(2014ZX03003010-002)+1 种基金the General Program of Natural Science Foundation of Jiangsu Province(BK20131299)the 2016 Science and Technology joint research and innovation foundation of Jiangsu province(SBY2016020323)
文摘In order to enhance the efficiency of spectrum utilization and reduce communication overhead in spectrum sharing process, we propose a two-stage dynamic spectrum sharing scheme in which cooperative and noncooperative modes are analyzed in both stages. In particular, the existence and the uniqueness of Nash Equilibrium(NE) strategies for noncooperative mode are proved. In addition, a distributed iterative algorithm is proposed to obtain the optimal solutions of the scheme. Simulation studies are carried out to show the performance comparison between two modes as well as the system revenue improvement of the proposed scheme compared with a conventional scheme without a virtual price control factor.
