胚胎染色体异常是复发性流产的最主要原因,其在高龄妊娠复发性流产中的比例较非高龄妊娠高出29%,目前尚无有效的治疗手段。本文认为阳明脉衰是导致高龄妊娠胚胎染色体异常复发性流产的重要病机,补益阳明津气、调整阴阳可以有效改善此种...胚胎染色体异常是复发性流产的最主要原因,其在高龄妊娠复发性流产中的比例较非高龄妊娠高出29%,目前尚无有效的治疗手段。本文认为阳明脉衰是导致高龄妊娠胚胎染色体异常复发性流产的重要病机,补益阳明津气、调整阴阳可以有效改善此种复发性流产的结局。从现代医学角度,本文从代谢–细胞–蛋白的角度出发,浅析补益阳明津气可能通过多靶点干预本病。全文基于浅析阳明的生理、病理及现代研究,为高龄妊娠胚胎染色体异常复发性流产的临床治疗提供参考。Chromosomal abnormality is the main cause of recurrent abortion, and its proportion in recurrent abortion of advanced pregnancy is 29% higher than that of non-advanced pregnancy. This paper considers that the failure of Yangming meridian is an important pathogenesis of recurrent abortion with chromosome abnormality in advanced pregnancy embryo. Tonifying Yangming Qi and regulating yin and yang can effectively improve the outcome of recurrent abortion. From the point of view of modern medicine, this paper analyzes that nourishing Yangming Qi may intervene this disease through multiple targets from the angle of metabolism-cell-protein. Based on the analysis of Yangming’s physiology, pathology and modern research, this paper provides reference for the clinical treatment of recurrent abortion with chromosomal abnormalities in advanced pregnancy embryos.展开更多
文摘胚胎染色体异常是复发性流产的最主要原因,其在高龄妊娠复发性流产中的比例较非高龄妊娠高出29%,目前尚无有效的治疗手段。本文认为阳明脉衰是导致高龄妊娠胚胎染色体异常复发性流产的重要病机,补益阳明津气、调整阴阳可以有效改善此种复发性流产的结局。从现代医学角度,本文从代谢–细胞–蛋白的角度出发,浅析补益阳明津气可能通过多靶点干预本病。全文基于浅析阳明的生理、病理及现代研究,为高龄妊娠胚胎染色体异常复发性流产的临床治疗提供参考。Chromosomal abnormality is the main cause of recurrent abortion, and its proportion in recurrent abortion of advanced pregnancy is 29% higher than that of non-advanced pregnancy. This paper considers that the failure of Yangming meridian is an important pathogenesis of recurrent abortion with chromosome abnormality in advanced pregnancy embryo. Tonifying Yangming Qi and regulating yin and yang can effectively improve the outcome of recurrent abortion. From the point of view of modern medicine, this paper analyzes that nourishing Yangming Qi may intervene this disease through multiple targets from the angle of metabolism-cell-protein. Based on the analysis of Yangming’s physiology, pathology and modern research, this paper provides reference for the clinical treatment of recurrent abortion with chromosomal abnormalities in advanced pregnancy embryos.
文摘目的探讨研究优势聚力护理模式在高龄妊娠期糖尿病(gestational diabetes mellitus,GDM)患者中的应用效果。方法选取2019年1月-2022年11月万载县妇幼保健院收治的60例高龄GDM患者为研究对象,根据随机数字表法分为对照组和实验组,各30例。对照组采取常规护理模式,实验组采取优势聚力护理模式,分析对比2组干预前后的血糖指标[空腹血糖(fiber bragg grating,FBG)、餐后2 h血糖(postprandial 2-hour blood glucose,PBG)、糖化血红蛋白(glycosylated hemoglobin,HbA1c)]、自我管理评分[糖尿病自我管理行为量表(summary of diabetes self care activities,SDSCA)、合理用药自我效能量表(self-efficacy for appropriate medication use scale,SEAMS)]、不良妊娠结局、护理满意率。结果干预后2组血糖指标均比干预前下降,且实验组FBG、PBG、HbA1c水平低于对照组(P<0.05);干预后2组自我管理及健康信念评分比干预前改善,且实验组SDSCA、SEAMS评分均优于对照组(P<0.05);实验组不良妊娠结局率低于对照组(P<0.05);实验组护理满意率较对照组更高(P<0.05)。结论优势聚力护理模式在高龄GDM患者中应用具有良好的护理效果,可改善患者的血糖指标,有利于患者自我管理行为的提升,减少不良妊娠结局出现的概率,具有较好的临床应用价值。