The rising prevalence of chronic multimorbidity poses substantial challenges to healthcare systems,necessitating the development of innovative management strategies to optimize patient care and system efficiency.The s...The rising prevalence of chronic multimorbidity poses substantial challenges to healthcare systems,necessitating the development of innovative management strategies to optimize patient care and system efficiency.The study by Fontalba-Navas et al investigates the implementation of a novel high complexity unit(HCU)specifically designed to improve the management of patients with chronic complex conditions.By adopting a multidisciplinary approach,the HCU aims to provide comprehensive,patient-centered care that enhances health outcomes and alleviates the strain on traditional hospital services.Utilizing a longitudinal analysis of data from the Basic Minimum Data Set,this study compares hospitalization metrics among the HCU,Internal Medicine,and other departments within a regional hospital throughout 2022.The findings reveal that the HCU's integrated care model significantly reduces readmission rates and boosts patient satisfaction compared to conventional care practices.The study highlights the HCU's potential as a replicable model for managing chronic multimorbidity,emphasizing its effectiveness in minimizing unnecessary hospitalizations and enhancing the overall quality of patient care.This innovative approach not only addresses the complexities associated with chronic multimorbid conditions but also offers a sustainable framework for healthcare systems confronting similar challenges.展开更多
Microwave-assisted rock-breaking technology,as a novel hybrid approach,is anticipated to facilitate the efficient excavation of complex rock formations.It is therefore crucial to understand the damage and failure mech...Microwave-assisted rock-breaking technology,as a novel hybrid approach,is anticipated to facilitate the efficient excavation of complex rock formations.It is therefore crucial to understand the damage and failure mechanisms of rocks that have been subjected to irradiation.In this study,uniaxial compression experiments were conducted on granite specimens after 1.4 kW microwave irradiation for varying durations.Furthermore,a numerical method was proposed to solve electromagnetic-thermal-mechanical coupling problems by integrating finite and discrete elements.The results demonstrated a differential temperature distribution(high temperature in the middle and low-temperature areas at the ends)in the granite specimens under microwave irradiation,which resulted in a notable reduction in their physical and mechanical properties.As the duration of irradiation increased,the rate of heating and the extent of strength reduction both diminished,while the morphology and distribution of cracks at ultimate failure became increasingly complex.The numerical method effectively addresses the simulation challenges associated with the electromagnetic selective heating of granite containing multiple polar minerals under microwave irradiation.This approach accounted for the non-uniform thermal expansion of the minerals and provided a comprehensive model of damage progression under compression.展开更多
Due to the fact that the emergency medicine distribution is vital to the quick response to urgent demand when an epidemic occurs, the optimal vaccine distribution approach is explored according to the epidemic diffusi...Due to the fact that the emergency medicine distribution is vital to the quick response to urgent demand when an epidemic occurs, the optimal vaccine distribution approach is explored according to the epidemic diffusion rule and different urgency degrees of affected areas with the background of the epidemic outbreak in a given region. First, the SIQR （susceptible, infected, quarantined,recovered） epidemic model with pulse vaccination is introduced to describe the epidemic diffusion rule and obtain the demanded vaccine in each pulse. Based on the SIQR model, the affected areas are clustered by using the self-organizing map （SOM） neutral network to qualify the results. Then, a dynamic vaccine distribution model is formulated, incorporating the results of clustering the affected areas with the goals of both reducing the transportation cost and decreasing the unsatisfied demand for the emergency logistics network. Numerical study with twenty affected areas and four distribution centers is carried out. The corresponding numerical results indicate that the proposed approach can make an outstanding contribution to controlling the affected areas with a relatively high degree of urgency, and the comparison results prove that the performance of the clustering method is superior to that of the non-clustering method on controlling epidemic diffusion.展开更多
Parameter identification, model calibration, and uncertainty quantification are important steps in the model-building process, and are necessary for obtaining credible results and valuable information. Sensitivity ana...Parameter identification, model calibration, and uncertainty quantification are important steps in the model-building process, and are necessary for obtaining credible results and valuable information. Sensitivity analysis of hydrological model is a key step in model uncertainty quantification, which can identify the dominant parameters, reduce the model calibration uncertainty, and enhance the model optimization efficiency. There are, however, some shortcomings in classical approaches, including the long duration of time and high computation cost required to quantitatively assess the sensitivity of a multiple-parameter hydrological model. For this reason, a two-step statistical evaluation framework using global techniques is presented. It is based on （1） a screening method （Morris） for qualitative ranking of parameters, and （2） a variance-based method integrated with a meta-model for quantitative sensitivity analysis, i.e., the Sobol method integrated with the response surface model （RSMSobol）. First, the Morris screening method was used to qualitatively identify the parameters＇ sensitivity, and then ten parameters were selected to quantify the sensitivity indices. Subsequently, the RSMSobol method was used to quantify the sensitivity, i.e., the first-order and total sensitivity indices based on the response surface model （RSM） were calculated. The RSMSobol method can not only quantify the sensitivity, but also reduce the computational cost, with good accuracy compared to the classical approaches. This approach will be effective and reliable in the global sensitivity analysis of a complex large-scale distributed hydrological model.展开更多
Net Primary Productivity （NPP） is one of the important biophysical variables of vegetation activity, and it plays an important role in studying global carbon cycle, carbon source and sink of ecosystem, and spatial a...Net Primary Productivity （NPP） is one of the important biophysical variables of vegetation activity, and it plays an important role in studying global carbon cycle, carbon source and sink of ecosystem, and spatial and temporal distribution of CO2. Remote sensing can provide broad view quickly, timely and multi-temporally, which makes it an attractive and powerful tool for studying ecosystem primary productivity, at scales ranging from local to global. This paper aims to use Moderate Resolution Imaging Spectroradiometer （MODIS） data to estimate and analyze spatial and temporal distribution of NPP of the northern Hebei Province in 2001 based on Carnegie-Ames-Stanford Approach （CASA） model. The spatial distribution of Absorbed Photosynthetically Active Radiation （APAR） of vegetation and light use efficiency in three geographical subregions, that is, Bashang Plateau Region, Basin Region in the northwestern Hebei Province and Yanshan Mountainous Region in the Northern Hebei Province were analyzed, and total NPP spatial distribution of the study area in 2001 was discussed. Based on 16-day MODIS Fraction of Photosynthetically Active Radiation absorbed by vegetation （FPAR） product, 16-day composite NPP dynamics were calculated using CASA model; the seasonal dynamics of vegetation NPP in three subreglons were also analyzed. Result reveals that the total NPP of the study area in 2001 was 25.1877 × 10^6gC/（m^2.a）, and NPP in 2001 ranged from 2 to 608gC/（m^2-a）, with an average of 337.516gC/（m^2.a）. NPP of the study area in 2001 accumulated mainly from May to September （DOY 129-272）, high NIP values appeared from June to August （DOY 177-204）, and the maximum NPP appeared from late July to mid-August （DOY 209-224）.展开更多
Two land surface schemes, one the standard Biosphere / Atmosphere Transfer Scheme Version ie (BOZ) and the other B1Z based on B0Z and heterogeneously-treated by' combined approach' , were co 'pled to the m...Two land surface schemes, one the standard Biosphere / Atmosphere Transfer Scheme Version ie (BOZ) and the other B1Z based on B0Z and heterogeneously-treated by' combined approach' , were co 'pled to the meso-scale model MM4, respectively. Through the calculations of equations from the companion paper, parameters representing land surface heterogeneity and suitable for the coupling models were found out. Three cases were simulated for heavy rainfalls during 36 hours, and the sensitivity of short-term weather modeling to the land surface heterogeneity was tested. Through the analysis of the simulations of the three heavy rainfalls, it was demonstrated that BIZ, compared with BOZ, could more realistically reflect the features of the land surface heterogeneity, therefore could more realistically reproduce the circulation and precipitation amount in the heavy rainfall processes of the three cases. This shows that even short-term weather is sensitive to the land surface heterogeneity, which is more obvious with time passing, and whose influence is more pronounced in the lower layer and gradually extends to the middle and upper layer. Through the analysis of these simulations with BlZ, it is suggested that the bulk effect of smaller-scale fluxes (i.e., the momentum, water vapor and sensible heat fluxes) near the s ig nificantly-heterogeneous land surface is to change the larger-scale (i.e., meso-scale) circulation, and then to influence the development of the low-level jets and precipitation. And also, the complexity of the land-atmosphere interaction was shown in these simulations.展开更多
To represent model uncertainties more comprehensively,a stochastically perturbed parameterization(SPP)scheme consisting of temporally and spatially varying perturbations of 18 parameters in the microphysics,convection...To represent model uncertainties more comprehensively,a stochastically perturbed parameterization(SPP)scheme consisting of temporally and spatially varying perturbations of 18 parameters in the microphysics,convection,boundary layer,and surface layer parameterization schemes,as well as the stochastically perturbed parameterization tendencies(SPPT)scheme,and the stochastic kinetic energy backscatter(SKEB)scheme,is applied in the Global and Regional Assimilation and Prediction Enhanced System-Regional Ensemble Prediction System(GRAPES-REPS)to evaluate and compare the general performance of various combinations of multiple stochastic physics schemes.Six experiments are performed for a summer month(1-30 June 2015)over China and multiple verification metrics are used.The results show that:(1)All stochastic experiments outperform the control(CTL)experiment,and all combinations of stochastic parameterization schemes perform better than the single SPP scheme,indicating that stochastic methods can effectively improve the forecast skill,and combinations of multiple stochastic parameterization schemes can better represent model uncertainties;(2)The combination of all three stochastic physics schemes(SPP,SPPT,and SKEB)outperforms any other combination of two schemes in precipitation forecasting and surface and upper-air verification to better represent the model uncertainties and improve the forecast skill;(3)Combining SKEB with SPP and/or SPPT results in a notable increase in the spread and reduction in outliers for the upper-air wind speed.SKEB directly perturbs the wind field and therefore its addition will greatly impact the upper-air wind-speed fields,and it contributes most to the improvement in spread and outliers for wind;(4)The introduction of SPP has a positive added value,and does not lead to large changes in the evolution of the kinetic energy(KE)spectrum at any wavelength;(5)The introduction of SPPT and SKEB would cause a 5%-10%and 30%-80%change in the KE of mesoscale systems,and all three stochastic schemes(SPP,SPPT,and SKEB)mainly affect the KE of mesoscale systems.This study indicates the potential of combining multiple stochastic physics schemes and lays a foundation for the future development and design of regional and global ensembles.展开更多
A new approach,gate-capacitance-shift (GCS) approach,is described for compact modeling.This approach is piecewise for various physical effects and comprises the gate-bias-dependent nature of corrections in the nanosca...A new approach,gate-capacitance-shift (GCS) approach,is described for compact modeling.This approach is piecewise for various physical effects and comprises the gate-bias-dependent nature of corrections in the nanoscale regime.Additionally,an approximate-analytical solution to the quantum mechanical (QM) effects in polysilicon (poly)-gates is obtained based on the density gradient model.It is then combined with the GCS approach to develop a compact model for these effects.The model results tally well with numerical simulation.Both the model results and simulation results indicate that the QM effects in poly-gates of nanoscale MOSFETs are non-negligible and have an opposite influence on the device characteristics as the poly-depletion (PD) effects do.展开更多
The performance of six statistical approaches,which can be used for selection of the best model to describe the growth of individual fish,was analyzed using simulated and real length-at-age data.The six approaches inc...The performance of six statistical approaches,which can be used for selection of the best model to describe the growth of individual fish,was analyzed using simulated and real length-at-age data.The six approaches include coefficient of determination(R2),adjusted coefficient of determination(adj.-R2),root mean squared error(RMSE),Akaike's information criterion(AIC),bias correction of AIC(AICc) and Bayesian information criterion(BIC).The simulation data were generated by five growth models with different numbers of parameters.Four sets of real data were taken from the literature.The parameters in each of the five growth models were estimated using the maximum likelihood method under the assumption of the additive error structure for the data.The best supported model by the data was identified using each of the six approaches.The results show that R2 and RMSE have the same properties and perform worst.The sample size has an effect on the performance of adj.-R2,AIC,AICc and BIC.Adj.-R2 does better in small samples than in large samples.AIC is not suitable to use in small samples and tends to select more complex model when the sample size becomes large.AICc and BIC have best performance in small and large sample cases,respectively.Use of AICc or BIC is recommended for selection of fish growth model according to the size of the length-at-age data.展开更多
We study the localized coherent structures ofa generally nonintegrable (2+ 1 )-dimensional KdV equation via a variable separation approach. In a special integrable case, the entrance of some arbitrary functions leads ...We study the localized coherent structures ofa generally nonintegrable (2+ 1 )-dimensional KdV equation via a variable separation approach. In a special integrable case, the entrance of some arbitrary functions leads to abundant coherent structures. However, in the general nonintegrable case, an additional condition has to be introduced for these arbitrary functions. Although the additional condition has been introduced into the solutions of the nonintegrable KdV equation, there still exist many interesting solitary wave structures. Especially, the nonintegrable KdV equation possesses the breather-like localized excitations, and the similar static ring soliton solutions as in the integrable case. Furthermor,in the integrable case, the interaction between two travelling ring solitons is elastic, while in the nonintegrable case we cannot find even the single travelling ring soliton solution.展开更多
Eringen's nonlocal elasticity theory is extensively employed for the analysis of nanostructures because it is able to capture nanoscale effects.Previous studies have revealed that using the differential form of th...Eringen's nonlocal elasticity theory is extensively employed for the analysis of nanostructures because it is able to capture nanoscale effects.Previous studies have revealed that using the differential form of the strain-driven version of this theory leads to paradoxical results in some cases,such as bending analysis of cantilevers,and recourse must be made to the integral version.In this article,a novel numerical approach is developed for the bending analysis of Euler-Bernoulli nanobeams in the context of strain-and stress-driven integral nonlocal models.This numerical approach is proposed for the direct solution to bypass the difficulties related to converting the integral governing equation into a differential equation.First,the governing equation is derived based on both strain-driven and stress-driven nonlocal models by means of the minimum total potential energy.Also,in each case,the governing equation is obtained in both strong and weak forms.To solve numerically the derived equations,matrix differential and integral operators are constructed based upon the finite difference technique and trapezoidal integration rule.It is shown that the proposed numerical approach can be efficiently applied to the strain-driven nonlocal model with the aim of resolving the mentioned paradoxes.Also,it is able to solve the problem based on the strain-driven model without inconsistencies of the application of this model that are reported in the literature.展开更多
In order to analyze the effects of backfill materials, geometries and slab setting on the settlement of bridge approach embankment, scale model was built based on the structural characteristics of bridge approach emba...In order to analyze the effects of backfill materials, geometries and slab setting on the settlement of bridge approach embankment, scale model was built based on the structural characteristics of bridge approach embankment, and scale model tests were carried out under different conditions. The results show that when graded gravels were selected as the backfill materials, the effect of setting approach slab to reduce the differential settlement is more prominent. When lime soils were selected as the backfill material, approach slab can moderate the longitudinal settlement slope. When using different backfill materials, the ultimate settlement of the positive trapezoidal backfill geometries is less than that of the inverted trapezoid, and the backfill geometries have little effect on the settlement slope.展开更多
A review of recent animal models of amyotrophic lateral sclerosis showed a large number of mi RNAs had altered levels of expression in the brain and spinal cord,motor neurons of spinal cord and brainstem,and hypogloss...A review of recent animal models of amyotrophic lateral sclerosis showed a large number of mi RNAs had altered levels of expression in the brain and spinal cord,motor neurons of spinal cord and brainstem,and hypoglossal,facial,and red motor nuclei and were mostly upregulated.Among the mi RNAs found to be upregulated in two of the studies were mi R-21,mi R-155,mi R-125 b,mi R-146 a,mi R-124,mi R-9,and mi R-19 b,while those downregulated in two of the studies included mi R-146 a,mi R-29,mi R-9,and mi R-125 b.A change of direction in mi RNA expression occurred in some tissues when compared(e.g.,mi R-29 b-3 p in cerebellum and spinal cord of wobbler mice at 40 days),or at different disease stages(e.g.,mi R-200 a in spinal cord of SOD1(G93 A)mice at 95 days vs.108 and 112 days).In the animal models,suppression of mi R-129-5 p resulted in increased lifespan,improved muscle strength,reduced neuromuscular junction degeneration,and tended to improve motor neuron survival in the SOD1(G93 A)mouse model.Suppression of mi R-155 was also associated with increased lifespan,while lowering of mi R-29 a tended to improve lifespan in males and increase muscle strength in SOD1(G93 A)mice.Overexpression of members of mi R-17~92 cluster improved motor neuron survival in SOD1(G93 A)mice.Treatment with an artificial mi RNA designed to target h SOD1 increased lifespan and improved muscle strength in SOD1(G93 A)animals.Further studies with animal models of amyotrophic lateral sclerosis are warranted to validate these findings and identify specific mi RNAs whose suppression or directed against h SOD1 results in increased lifespan,improved muscle strength,reduced neuromuscular junction degeneration,and improved motor neuron survival in SOD1(G93 A)animals.展开更多
The spring (March-April-May) rainfall over northern China (SPRNC) is predicted by using the interannual increment approach. DY denotes the difference between the current year and previous years. The seasonal forecast ...The spring (March-April-May) rainfall over northern China (SPRNC) is predicted by using the interannual increment approach. DY denotes the difference between the current year and previous years. The seasonal forecast model for the DY of SPRNC is constructed based on the data that are taken from the 1965-2002 period (38 years), in which six predictors are available no later than the current month of February. This is favorable so that the seasonal forecasts can be made one month ahead. Then, SPRNC and the percentage anomaly of SPRNC are obtained by the predicted DY of SPRNC. The model performs well in the prediction of the inter-annual variation of the DY of SPRNC during 1965-2002, with a correlation coefficient between the predicted and observed DY of SPRNC of 0.87. This accounts for 76% of the total variance, with a low value for the average root mean square error (RMSE) of 20%. Both the results of the hindcast for the period of 2003-2010 (eight years) and the cross-validation test for the period of 1965-2009 (45 years) illustrate the good prediction capability of the model, with a small mean relative error of 10%, an RMSE of 17% and a high rate of coherence of 87.5% for the hindcasts of the percentage anomaly of SPRNC.展开更多
In order to deal with modeling problem of a pressure balance system with time-delay, nonlinear, time-varying and uncertain characteristics, an intelligent modeling procedure is proposed, which is based on artificial n...In order to deal with modeling problem of a pressure balance system with time-delay, nonlinear, time-varying and uncertain characteristics, an intelligent modeling procedure is proposed, which is based on artificial neural network(ANN) and input-output data of the system during shield tunneling and can overcome the precision problem in mechanistic modeling(MM) approach. The computational results show that the training algorithm with Gauss-Newton optimization has fast convergent speed. The experimental investigation indicates that, compared with mechanistic modeling approach, intelligent modeling procedure can obviously increase the precision in both soil pressure fitting and forecasting period. The effectiveness and accuracy of proposed intelligent modeling procedure are verified in laboratory tests.展开更多
基金Supported by Basic Science Research Program through the National Research Foundation of Korea(NRF)funded by the Ministry of Education,No.NRF-RS-2023-00237287.
文摘The rising prevalence of chronic multimorbidity poses substantial challenges to healthcare systems,necessitating the development of innovative management strategies to optimize patient care and system efficiency.The study by Fontalba-Navas et al investigates the implementation of a novel high complexity unit(HCU)specifically designed to improve the management of patients with chronic complex conditions.By adopting a multidisciplinary approach,the HCU aims to provide comprehensive,patient-centered care that enhances health outcomes and alleviates the strain on traditional hospital services.Utilizing a longitudinal analysis of data from the Basic Minimum Data Set,this study compares hospitalization metrics among the HCU,Internal Medicine,and other departments within a regional hospital throughout 2022.The findings reveal that the HCU's integrated care model significantly reduces readmission rates and boosts patient satisfaction compared to conventional care practices.The study highlights the HCU's potential as a replicable model for managing chronic multimorbidity,emphasizing its effectiveness in minimizing unnecessary hospitalizations and enhancing the overall quality of patient care.This innovative approach not only addresses the complexities associated with chronic multimorbid conditions but also offers a sustainable framework for healthcare systems confronting similar challenges.
基金funded by the Postgraduate Research and Practice Innovation Program of Jiangsu Province(Grant No.KYCX23_2744)the Fundamental Research Funds for the Central Universities(Grant No.2023XSCX051)the Graduate Innovation Program of China University of Mining and Technology(Grant No.2023WLKXJ182).
文摘Microwave-assisted rock-breaking technology,as a novel hybrid approach,is anticipated to facilitate the efficient excavation of complex rock formations.It is therefore crucial to understand the damage and failure mechanisms of rocks that have been subjected to irradiation.In this study,uniaxial compression experiments were conducted on granite specimens after 1.4 kW microwave irradiation for varying durations.Furthermore,a numerical method was proposed to solve electromagnetic-thermal-mechanical coupling problems by integrating finite and discrete elements.The results demonstrated a differential temperature distribution(high temperature in the middle and low-temperature areas at the ends)in the granite specimens under microwave irradiation,which resulted in a notable reduction in their physical and mechanical properties.As the duration of irradiation increased,the rate of heating and the extent of strength reduction both diminished,while the morphology and distribution of cracks at ultimate failure became increasingly complex.The numerical method effectively addresses the simulation challenges associated with the electromagnetic selective heating of granite containing multiple polar minerals under microwave irradiation.This approach accounted for the non-uniform thermal expansion of the minerals and provided a comprehensive model of damage progression under compression.
基金The National Natural Science Foundation of China (No.70671021)
文摘Due to the fact that the emergency medicine distribution is vital to the quick response to urgent demand when an epidemic occurs, the optimal vaccine distribution approach is explored according to the epidemic diffusion rule and different urgency degrees of affected areas with the background of the epidemic outbreak in a given region. First, the SIQR （susceptible, infected, quarantined,recovered） epidemic model with pulse vaccination is introduced to describe the epidemic diffusion rule and obtain the demanded vaccine in each pulse. Based on the SIQR model, the affected areas are clustered by using the self-organizing map （SOM） neutral network to qualify the results. Then, a dynamic vaccine distribution model is formulated, incorporating the results of clustering the affected areas with the goals of both reducing the transportation cost and decreasing the unsatisfied demand for the emergency logistics network. Numerical study with twenty affected areas and four distribution centers is carried out. The corresponding numerical results indicate that the proposed approach can make an outstanding contribution to controlling the affected areas with a relatively high degree of urgency, and the comparison results prove that the performance of the clustering method is superior to that of the non-clustering method on controlling epidemic diffusion.
基金supported by the National Natural Science Foundation of China (Grant No. 41271003)the National Basic Research Program of China (Grants No. 2010CB428403 and 2010CB951103)
文摘Parameter identification, model calibration, and uncertainty quantification are important steps in the model-building process, and are necessary for obtaining credible results and valuable information. Sensitivity analysis of hydrological model is a key step in model uncertainty quantification, which can identify the dominant parameters, reduce the model calibration uncertainty, and enhance the model optimization efficiency. There are, however, some shortcomings in classical approaches, including the long duration of time and high computation cost required to quantitatively assess the sensitivity of a multiple-parameter hydrological model. For this reason, a two-step statistical evaluation framework using global techniques is presented. It is based on （1） a screening method （Morris） for qualitative ranking of parameters, and （2） a variance-based method integrated with a meta-model for quantitative sensitivity analysis, i.e., the Sobol method integrated with the response surface model （RSMSobol）. First, the Morris screening method was used to qualitatively identify the parameters＇ sensitivity, and then ten parameters were selected to quantify the sensitivity indices. Subsequently, the RSMSobol method was used to quantify the sensitivity, i.e., the first-order and total sensitivity indices based on the response surface model （RSM） were calculated. The RSMSobol method can not only quantify the sensitivity, but also reduce the computational cost, with good accuracy compared to the classical approaches. This approach will be effective and reliable in the global sensitivity analysis of a complex large-scale distributed hydrological model.
基金Under the auspices of the National Natural Science Foundation of China (No. 40571117), the Knowledge Innovation Program of Chinese Academy of Sciences (No. KZCX3-SW-338), Research foundation of the State Key Laboratory of Remote Sensing Science, Institute of Remote Sensing Applications, Chinese Academy of Sciences (KQ060006)
文摘Net Primary Productivity （NPP） is one of the important biophysical variables of vegetation activity, and it plays an important role in studying global carbon cycle, carbon source and sink of ecosystem, and spatial and temporal distribution of CO2. Remote sensing can provide broad view quickly, timely and multi-temporally, which makes it an attractive and powerful tool for studying ecosystem primary productivity, at scales ranging from local to global. This paper aims to use Moderate Resolution Imaging Spectroradiometer （MODIS） data to estimate and analyze spatial and temporal distribution of NPP of the northern Hebei Province in 2001 based on Carnegie-Ames-Stanford Approach （CASA） model. The spatial distribution of Absorbed Photosynthetically Active Radiation （APAR） of vegetation and light use efficiency in three geographical subregions, that is, Bashang Plateau Region, Basin Region in the northwestern Hebei Province and Yanshan Mountainous Region in the Northern Hebei Province were analyzed, and total NPP spatial distribution of the study area in 2001 was discussed. Based on 16-day MODIS Fraction of Photosynthetically Active Radiation absorbed by vegetation （FPAR） product, 16-day composite NPP dynamics were calculated using CASA model; the seasonal dynamics of vegetation NPP in three subreglons were also analyzed. Result reveals that the total NPP of the study area in 2001 was 25.1877 × 10^6gC/（m^2.a）, and NPP in 2001 ranged from 2 to 608gC/（m^2-a）, with an average of 337.516gC/（m^2.a）. NPP of the study area in 2001 accumulated mainly from May to September （DOY 129-272）, high NIP values appeared from June to August （DOY 177-204）, and the maximum NPP appeared from late July to mid-August （DOY 209-224）.
基金the NKBRSF Project! G 1999043400 the CNSF Project! 49735180.
文摘Two land surface schemes, one the standard Biosphere / Atmosphere Transfer Scheme Version ie (BOZ) and the other B1Z based on B0Z and heterogeneously-treated by' combined approach' , were co 'pled to the meso-scale model MM4, respectively. Through the calculations of equations from the companion paper, parameters representing land surface heterogeneity and suitable for the coupling models were found out. Three cases were simulated for heavy rainfalls during 36 hours, and the sensitivity of short-term weather modeling to the land surface heterogeneity was tested. Through the analysis of the simulations of the three heavy rainfalls, it was demonstrated that BIZ, compared with BOZ, could more realistically reflect the features of the land surface heterogeneity, therefore could more realistically reproduce the circulation and precipitation amount in the heavy rainfall processes of the three cases. This shows that even short-term weather is sensitive to the land surface heterogeneity, which is more obvious with time passing, and whose influence is more pronounced in the lower layer and gradually extends to the middle and upper layer. Through the analysis of these simulations with BlZ, it is suggested that the bulk effect of smaller-scale fluxes (i.e., the momentum, water vapor and sensible heat fluxes) near the s ig nificantly-heterogeneous land surface is to change the larger-scale (i.e., meso-scale) circulation, and then to influence the development of the low-level jets and precipitation. And also, the complexity of the land-atmosphere interaction was shown in these simulations.
基金National Key Research and Development(R&D)Program of China,(Grant No.2018YFC1507405).
文摘To represent model uncertainties more comprehensively,a stochastically perturbed parameterization(SPP)scheme consisting of temporally and spatially varying perturbations of 18 parameters in the microphysics,convection,boundary layer,and surface layer parameterization schemes,as well as the stochastically perturbed parameterization tendencies(SPPT)scheme,and the stochastic kinetic energy backscatter(SKEB)scheme,is applied in the Global and Regional Assimilation and Prediction Enhanced System-Regional Ensemble Prediction System(GRAPES-REPS)to evaluate and compare the general performance of various combinations of multiple stochastic physics schemes.Six experiments are performed for a summer month(1-30 June 2015)over China and multiple verification metrics are used.The results show that:(1)All stochastic experiments outperform the control(CTL)experiment,and all combinations of stochastic parameterization schemes perform better than the single SPP scheme,indicating that stochastic methods can effectively improve the forecast skill,and combinations of multiple stochastic parameterization schemes can better represent model uncertainties;(2)The combination of all three stochastic physics schemes(SPP,SPPT,and SKEB)outperforms any other combination of two schemes in precipitation forecasting and surface and upper-air verification to better represent the model uncertainties and improve the forecast skill;(3)Combining SKEB with SPP and/or SPPT results in a notable increase in the spread and reduction in outliers for the upper-air wind speed.SKEB directly perturbs the wind field and therefore its addition will greatly impact the upper-air wind-speed fields,and it contributes most to the improvement in spread and outliers for wind;(4)The introduction of SPP has a positive added value,and does not lead to large changes in the evolution of the kinetic energy(KE)spectrum at any wavelength;(5)The introduction of SPPT and SKEB would cause a 5%-10%and 30%-80%change in the KE of mesoscale systems,and all three stochastic schemes(SPP,SPPT,and SKEB)mainly affect the KE of mesoscale systems.This study indicates the potential of combining multiple stochastic physics schemes and lays a foundation for the future development and design of regional and global ensembles.
文摘A new approach,gate-capacitance-shift (GCS) approach,is described for compact modeling.This approach is piecewise for various physical effects and comprises the gate-bias-dependent nature of corrections in the nanoscale regime.Additionally,an approximate-analytical solution to the quantum mechanical (QM) effects in polysilicon (poly)-gates is obtained based on the density gradient model.It is then combined with the GCS approach to develop a compact model for these effects.The model results tally well with numerical simulation.Both the model results and simulation results indicate that the QM effects in poly-gates of nanoscale MOSFETs are non-negligible and have an opposite influence on the device characteristics as the poly-depletion (PD) effects do.
基金Supported by the High Technology Research and Development Program of China (863 Program,No2006AA100301)
文摘The performance of six statistical approaches,which can be used for selection of the best model to describe the growth of individual fish,was analyzed using simulated and real length-at-age data.The six approaches include coefficient of determination(R2),adjusted coefficient of determination(adj.-R2),root mean squared error(RMSE),Akaike's information criterion(AIC),bias correction of AIC(AICc) and Bayesian information criterion(BIC).The simulation data were generated by five growth models with different numbers of parameters.Four sets of real data were taken from the literature.The parameters in each of the five growth models were estimated using the maximum likelihood method under the assumption of the additive error structure for the data.The best supported model by the data was identified using each of the six approaches.The results show that R2 and RMSE have the same properties and perform worst.The sample size has an effect on the performance of adj.-R2,AIC,AICc and BIC.Adj.-R2 does better in small samples than in large samples.AIC is not suitable to use in small samples and tends to select more complex model when the sample size becomes large.AICc and BIC have best performance in small and large sample cases,respectively.Use of AICc or BIC is recommended for selection of fish growth model according to the size of the length-at-age data.
文摘We study the localized coherent structures ofa generally nonintegrable (2+ 1 )-dimensional KdV equation via a variable separation approach. In a special integrable case, the entrance of some arbitrary functions leads to abundant coherent structures. However, in the general nonintegrable case, an additional condition has to be introduced for these arbitrary functions. Although the additional condition has been introduced into the solutions of the nonintegrable KdV equation, there still exist many interesting solitary wave structures. Especially, the nonintegrable KdV equation possesses the breather-like localized excitations, and the similar static ring soliton solutions as in the integrable case. Furthermor,in the integrable case, the interaction between two travelling ring solitons is elastic, while in the nonintegrable case we cannot find even the single travelling ring soliton solution.
文摘Eringen's nonlocal elasticity theory is extensively employed for the analysis of nanostructures because it is able to capture nanoscale effects.Previous studies have revealed that using the differential form of the strain-driven version of this theory leads to paradoxical results in some cases,such as bending analysis of cantilevers,and recourse must be made to the integral version.In this article,a novel numerical approach is developed for the bending analysis of Euler-Bernoulli nanobeams in the context of strain-and stress-driven integral nonlocal models.This numerical approach is proposed for the direct solution to bypass the difficulties related to converting the integral governing equation into a differential equation.First,the governing equation is derived based on both strain-driven and stress-driven nonlocal models by means of the minimum total potential energy.Also,in each case,the governing equation is obtained in both strong and weak forms.To solve numerically the derived equations,matrix differential and integral operators are constructed based upon the finite difference technique and trapezoidal integration rule.It is shown that the proposed numerical approach can be efficiently applied to the strain-driven nonlocal model with the aim of resolving the mentioned paradoxes.Also,it is able to solve the problem based on the strain-driven model without inconsistencies of the application of this model that are reported in the literature.
基金Project(51978068) supported by the National Natural Science Foundation of ChinaProject(2018YFE0103800) supported by the National Key R&D Program of China+1 种基金Project(2017M620434) supported by the China Postdoctoral Science FoundationProject(310821173501) support by the Special Fund for Basic Scientific Research of Central College of Chang’an University, China。
文摘In order to analyze the effects of backfill materials, geometries and slab setting on the settlement of bridge approach embankment, scale model was built based on the structural characteristics of bridge approach embankment, and scale model tests were carried out under different conditions. The results show that when graded gravels were selected as the backfill materials, the effect of setting approach slab to reduce the differential settlement is more prominent. When lime soils were selected as the backfill material, approach slab can moderate the longitudinal settlement slope. When using different backfill materials, the ultimate settlement of the positive trapezoidal backfill geometries is less than that of the inverted trapezoid, and the backfill geometries have little effect on the settlement slope.
文摘A review of recent animal models of amyotrophic lateral sclerosis showed a large number of mi RNAs had altered levels of expression in the brain and spinal cord,motor neurons of spinal cord and brainstem,and hypoglossal,facial,and red motor nuclei and were mostly upregulated.Among the mi RNAs found to be upregulated in two of the studies were mi R-21,mi R-155,mi R-125 b,mi R-146 a,mi R-124,mi R-9,and mi R-19 b,while those downregulated in two of the studies included mi R-146 a,mi R-29,mi R-9,and mi R-125 b.A change of direction in mi RNA expression occurred in some tissues when compared(e.g.,mi R-29 b-3 p in cerebellum and spinal cord of wobbler mice at 40 days),or at different disease stages(e.g.,mi R-200 a in spinal cord of SOD1(G93 A)mice at 95 days vs.108 and 112 days).In the animal models,suppression of mi R-129-5 p resulted in increased lifespan,improved muscle strength,reduced neuromuscular junction degeneration,and tended to improve motor neuron survival in the SOD1(G93 A)mouse model.Suppression of mi R-155 was also associated with increased lifespan,while lowering of mi R-29 a tended to improve lifespan in males and increase muscle strength in SOD1(G93 A)mice.Overexpression of members of mi R-17~92 cluster improved motor neuron survival in SOD1(G93 A)mice.Treatment with an artificial mi RNA designed to target h SOD1 increased lifespan and improved muscle strength in SOD1(G93 A)animals.Further studies with animal models of amyotrophic lateral sclerosis are warranted to validate these findings and identify specific mi RNAs whose suppression or directed against h SOD1 results in increased lifespan,improved muscle strength,reduced neuromuscular junction degeneration,and improved motor neuron survival in SOD1(G93 A)animals.
基金Innovation Key Program of the Chinese Academy of Sciences(KZCX2-YW-QN202)Global Climate Change Research National Basic Research Program of China(2010CB950304)+1 种基金Innovation Key Program of the Chinese Academy of Sciences (KZCX2-YW-BR-14)Special Fund for Public Welfare Industry (Meteorology) (GYHY200906018)
文摘The spring (March-April-May) rainfall over northern China (SPRNC) is predicted by using the interannual increment approach. DY denotes the difference between the current year and previous years. The seasonal forecast model for the DY of SPRNC is constructed based on the data that are taken from the 1965-2002 period (38 years), in which six predictors are available no later than the current month of February. This is favorable so that the seasonal forecasts can be made one month ahead. Then, SPRNC and the percentage anomaly of SPRNC are obtained by the predicted DY of SPRNC. The model performs well in the prediction of the inter-annual variation of the DY of SPRNC during 1965-2002, with a correlation coefficient between the predicted and observed DY of SPRNC of 0.87. This accounts for 76% of the total variance, with a low value for the average root mean square error (RMSE) of 20%. Both the results of the hindcast for the period of 2003-2010 (eight years) and the cross-validation test for the period of 1965-2009 (45 years) illustrate the good prediction capability of the model, with a small mean relative error of 10%, an RMSE of 17% and a high rate of coherence of 87.5% for the hindcasts of the percentage anomaly of SPRNC.
基金Project(2013CB035402) supported by the National Basic Research Program of ChinaProjects(51105048,51209028) supported by the National Natural Science Foundation of China
文摘In order to deal with modeling problem of a pressure balance system with time-delay, nonlinear, time-varying and uncertain characteristics, an intelligent modeling procedure is proposed, which is based on artificial neural network(ANN) and input-output data of the system during shield tunneling and can overcome the precision problem in mechanistic modeling(MM) approach. The computational results show that the training algorithm with Gauss-Newton optimization has fast convergent speed. The experimental investigation indicates that, compared with mechanistic modeling approach, intelligent modeling procedure can obviously increase the precision in both soil pressure fitting and forecasting period. The effectiveness and accuracy of proposed intelligent modeling procedure are verified in laboratory tests.
