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Research on the Construction of Intellectual Property System and Optimization of Business Environment in China
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作者 Zhang Xue Lyu Guofu 《科技与法律(中英文)》 2025年第1期125-137,共13页
With the rapid development of globalization and information technology,intellectual property has been one of the key drivers of economic growth,and the construction of intellectual property system has become an import... With the rapid development of globalization and information technology,intellectual property has been one of the key drivers of economic growth,and the construction of intellectual property system has become an important criterion for measuring the quality of business environment.This article is intended to explore the current status of intellectual property system construction in China,the challenges,and its relationship with the business environment,to propose the corresponding countermeasures and suggestions.The study finds that the legal system of intellectual property in China is gradually improving,and judicial and administrative protection are continuously strengthened.However,the challenges still remain such as frequent infringements,rights hard to protect and insufficient international cooperation.These issues not only affect the legitimate rights and interests of innovation entities,but also for the market fairness and the level of the business environment.Therefore,this article proposes that strengthening the perfection of the intellectual property legal system,enhancing intellectual property services and support capabilities,strengthening international cooperation and exchanges,and accelerating the cultivation of composite talents.It aims to provide theoretical references for the construction of intellectual property system and the optimization of the business environment,promote the high-quality development of economy and enhance the global competitiveness of the country. 展开更多
关键词 intellectual property business environment system construction economic development
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Portable Software Environment for Ultrahigh-Resolution ELM Development on GPUs
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作者 Dali Wang Peter Schwartz +5 位作者 Fengming Yuan Franklin Eaglebarge Danial Riccuito Peter Thornton Chris Layton Qinglei Cao 《Journal of Computer and Communications》 2025年第2期28-36,共9页
This paper presents our endeavors in developing the large-scale, ultra-high-resolution E3SM Land Model (uELM), specifically designed for exascale computers furnished with accelerators such as Nvidia GPUs. The uELM is ... This paper presents our endeavors in developing the large-scale, ultra-high-resolution E3SM Land Model (uELM), specifically designed for exascale computers furnished with accelerators such as Nvidia GPUs. The uELM is a sophisticated code that substantially relies on High-Performance Computing (HPC) environments, necessitating particular machine and software configurations. To facilitate community-based uELM developments employing GPUs, we have created a portable, standalone software environment preconfigured with uELM input datasets, simulation cases, and source code. This environment, utilizing Docker, encompasses all essential code, libraries, and system software for uELM development on GPUs. It also features a functional unit test framework and an offline model testbed for comprehensive numerical experiments. From a technical perspective, the paper discusses GPU-ready container generations, uELM code management, and input data distribution across computational platforms. Lastly, the paper demonstrates the use of environment for functional unit testing, end-to-end simulation on CPUs and GPUs, and collaborative code development. 展开更多
关键词 E3SM Land Model Ultrahigh-Resolution ELM Portable Software environment GPU-Ready environment
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Influence of ultrafine cement on cement-soil in peat soil environment of Dianchi Lake
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作者 CAO Jing SUN Huafeng +5 位作者 HUANG Siyang KONG Cheng LIU Fangyi LIU Fuhua TIAN Lin ZHU Weiming 《土木与环境工程学报(中英文)》 北大核心 2025年第2期1-12,共12页
Treatment of peat soil foundation in Yunnan surrounding Dianchi and Erhai Lakes poses complex problems for engineering projects.It is insufficient to rely on ordinary cement to reinforce peat soil.In order to make the... Treatment of peat soil foundation in Yunnan surrounding Dianchi and Erhai Lakes poses complex problems for engineering projects.It is insufficient to rely on ordinary cement to reinforce peat soil.In order to make the reinforcement reliable,this experiment mixed(ultrafine cement)UFC into ordinary cement to form a composite solidify agent.This study aimed to analyze the influence of UFC proportion on the strength of cement-soil in the peat soil environment.Unconfined compressive strength(UCS)and scanning electron microscope(SEM)tests were conducted on samples soaked for 28 and 90 days,respectively.The test results show that without considering the effects of Humic Acid(HA)and Fulvic Acid(FA),incorporating UFC can significantly improve the UCS of cement-soil.The rapid hydration of the fine particles generates a large number of cementitious products,improves the cohesion of the soil skeleton,and fills the pores.However,when the proportion of UFC increases,the aggregate structure formed by a larger quantity of fine particles reduces the hydration rate and degree of cement hydration,making the UCS growth rate of cement-soil insignificant.In the peat soil environment,HA significantly weakened the UCS of cement-soil in both physical and chemical aspects.However,UFC can mitigate the adverse effect of HA on cement-soil by its small particle size,high surface energy,and solid binding ability.In addition,FA has a positive effect on the UCS of cement-soil soaked for 28 days and 90 days.The UFC addition could promote the enhancement effect of FA on cement-soil UCS.SEM test results showed that cement hydration products increased significantly with the increase of UFC proportion,and cementation between hydration products and soil particles was enhanced.The size and connectivity of cement-soil pores were significantly reduced,thereby improving cement-soil structural integrity. 展开更多
关键词 peat soil environment ultrafine cement(UFC) cement-soil strength test MICROSTRUCTURE
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Environmental Impacts of Uncontrolled Waste Collection Points in the Urban Municipality of Coyah, Guinea, West Africa
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作者 Marie Rose Bangoura Alain Gbilimou Lucien Solie 《Journal of Geoscience and Environment Protection》 2025年第1期302-315,共14页
This article is descriptive research that takes into account the growing concerns of the authorities of the municipality of Coyah regarding waste management, as well as our desire to contribute to improving the living... This article is descriptive research that takes into account the growing concerns of the authorities of the municipality of Coyah regarding waste management, as well as our desire to contribute to improving the living conditions of the inhabitants of this region. The main objective is to assess the environmental impacts of uncontrolled waste collection points on the receiving environments, by characterizing and evaluating them. This will make it possible to propose appropriate measures for rational and sustainable management of the environment in Coyah. The study addresses the characterization and assessment of pollution of receiving environments, including water, soil and air. Environmental analyses were carried out according to standard methods of EPA (1997), adapted to the equipment of the companies Hach, Millipore and Verlan. During the environmental impact assessment, we identified the sources of pollution and assessed the potential impacts. This research highlighted the pollution of receiving environments by waste located in the vicinity of collection points, while considering solutions for efficient and sustainable waste management. 展开更多
关键词 environmental Impacts Waste Sustainable Management Receiving environment Collection Points
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Diagnostic Reference Levels, Protection of Patients and the Environment against Harmful Effects of X-Rays: Practice of Pediatric Radiology in Six General Reference Hospitals of the Kongo Central Province, DRC
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作者 Minga Barthelemy Bope Kwete Pembi Francy Pembi +13 位作者 Luwaya Ndombasi Blanchard Ipende Lansikub Jean Sokomoy Nankwa Joséphine Mukadi Mukadi Jules Thomas Byeka Mukambilwa Dorksin Kapia Patrice Milambo Binkedi Ngoma Richard Omombo Ngongo Timothée Mbiango Mabanza Francine Kafinga Ketibula Charly Nkwadi Katolo Adolphe Ngongo Mulemba Tchite Aya Nkole Benjamin Kafinga Luzolo Emery Masandi Milondo Alphonse 《Journal of Biosciences and Medicines》 2025年第1期47-59,共13页
The purpose of this research was to evaluate radiological safety in pediatric radiology in hospitals in the Kongo Central province of the DRC. To this end, we surveyed a convenience sample of 50 health professionals, ... The purpose of this research was to evaluate radiological safety in pediatric radiology in hospitals in the Kongo Central province of the DRC. To this end, we surveyed a convenience sample of 50 health professionals, including 10 radiologists working in the hospitals covered by the survey, to assess the practice of pediatric radiology and the degree of compliance with radiation protection principles for the safety of children and the environment. We collected radiophysical parameters to calculate entrance doses in pediatric radiology in radiology departments to determine the dosimetric level by comparison with the diagnostic reference levels of the International Commission on Radiological Protection (ICRP). All in all, we found that in Kongo Central in the DRC, many health personnel surveyed reported that more than 30% of requested radiological examinations are not justified. Also, after comparing the entrance doses produced in the surveyed departments with those of the International Commission on Radiological Protection (ICRP), a statistically significant difference was found in pediatric radiology between the average doses in five out of six surveyed departments and those of the ICRP. Therefore, almost all of the surveyed departments were found to be highly irradiating in children, while excessive X-ray irradiation in children can have significant effects due to their increased sensitivity to radiation. Among the risks are: increased cancer risks, damage to developing cells, potential genetic effects, and neurological effects. This is why support for implementing radiation protection principles is a necessity to promote the safety of patients and the environment against the harmful effects of X-rays in conventional radiology. 展开更多
关键词 Diagnostic Reference Levels (DRLs) Radiation Protection environment and Pediatric Radiology
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Non-cooperative target extraction in complex industrial environment based on image segmentation
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作者 WU Xiaojun WANG Peng +2 位作者 ZHAO He YU Xianzhe LI Tiancheng 《Journal of Measurement Science and Instrumentation》 2025年第1期119-127,共9页
In complex industrial scenes,it is difficult to acquire high-precision non-cooperative target pose under monocular visual servo control.This paper presents a new method of target extraction and high-precision edge fit... In complex industrial scenes,it is difficult to acquire high-precision non-cooperative target pose under monocular visual servo control.This paper presents a new method of target extraction and high-precision edge fitting for the wheel of the sintering trolley in steel production,which fuses multiple target extraction algorithms adapting to the working environment of the target.Firstly,based on obvious difference between the pixels of the target image and the non-target image in the gray histogram,these pixels were classified and then segmented in intraclass,removing interference factors and remaining the target image.Then,multiple segmentation results were merged and a final target image was obtained after small connected regions were eliminated.In the edge fitting stage,the edge fitting method with best-circumscribed rectangle was proposed to accurately fit the circular target edge.Finally,PnP algorithm was adopted for pose measurement of the target.The experimental results showed that the average estimation error of pose angleγwith respect to the z-axis rotation was 0.2346°,the average measurement error of pose angleαwith respect to the x-axis rotation was 0.1703°,and the average measurement error of pose angle β with respect to the y-axis rotation was 0.2275°.The proposed method has practical application value. 展开更多
关键词 digital image processing industrial environment non-cooperative target pose measurement
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CO hydrogenation conversion driven by micro-environments of active sites over iron carbide catalysts
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作者 Nan Song Xingxing Li +6 位作者 Ebtihal Abograin Wenyao Chen Junbo Cao Jing Zhang De Chen Xuezhi Duan Xinggui Zhou 《Green Energy & Environment》 2025年第2期367-373,共7页
Essentially clearing the structure-activity relationship between iron carbide catalysts involving multiple active centers to understand the reaction mechanism of CO hydrogenation conversion process is still a great ch... Essentially clearing the structure-activity relationship between iron carbide catalysts involving multiple active centers to understand the reaction mechanism of CO hydrogenation conversion process is still a great challenge.Here,two main micro-environment factors,namely electronic properties and geometrical effects were found to have an integrated effect on the mechanism of CO hydrogenation conversion,involving active sites on multiple crystal phases.The Bader charge of the surface Fe atoms on the active sites had a guiding effect on the CO activation pathway,while the spatial configuration of the active sites greatly affected the energy barriers of CO activation.Although the defective surfaces were more conducive to CO activation,the defective sites were not the only sites to dissociate CO,as CO always tended to dissociate in a wider area.This synergistic effect of the micro-environment also occurred during the CO conversion process.Surface C atoms on relatively flat configurations were more likely to form methane,while the electronic properties of the active sites could effectively describe the C-C coupling process,as well as distinguish the coupling mechanisms. 展开更多
关键词 MICRO-environment CO hydrogenation conversion Electronic property Local environment Synergistic effect
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Responses of yield,root traits and their plasticity to the nitrogen environment in nitrogen-efficient cultivars of drip-irrigated rice
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作者 Qingyun Tang Guodong Wang +2 位作者 Lei Zhao Zhiwen Song Yuxiang Li 《Journal of Integrative Agriculture》 2025年第2期480-496,共17页
The responses of drip-irrigated rice physiological traits to water and fertilizers have been widely studied.However,the responses of yield,root traits and their plasticity to the nitrogen environment in different nitr... The responses of drip-irrigated rice physiological traits to water and fertilizers have been widely studied.However,the responses of yield,root traits and their plasticity to the nitrogen environment in different nitrogen-efficient cultivars are not fully understood.An experiment was conducted from 2020-2022 with a high nitrogen use efficiency(high-NUE)cultivar(T-43)and a low-NUE cultivar(LX-3),and four nitrogen levels(0,150,300,and 450 kg ha^(-1))under drip irrigation in large fields.The aim was to study the relationships between root morphology,conformation,biomass,and endogenous hormone contents,yield and NUE.The results showed three main points:1)Under the same N application rate,compared with LX-3,the yield,N partial factor productivity(PFP),fine root length density(FRLD),shoot dry weight(SDW),root indole-3-acetic acid(IAA),and root zeatin and zeatin riboside(Z+ZR)of T-43 were significantly greater by11.4-18.9,11.3-13.5,11.6-15.7,9.9-31.1,6.1-48.1,and 22.8-73.6%,respectively,while the root-shoot ratio(RSR)and root abscisic acid(ABA)were significantly lower(P<0.05);2)nitrogen treatment significantly increased the rice root morphological indexes and endogenous hormone contents(P<0.05).Compared to N0,the yield,RLD,surface area density(SAD),root volume density(RVD),and root endogenous hormones(IAA,Z+ZR)were significantly increased in both cultivars under N2 by 61.6-71.6,64.2-74.0,69.9-105.6,6.67-9.91,54.0-67.8,and 51.4-58.9%,respectively.Compared with N3,the PFP and N agronomic efficiency(NAE)of nitrogen fertilizer under N2 increased by 52.3-62.4 and39.2-63.0%,respectively;3)the responses of root trait plasticity to the N environment significantly differed between the cultivars(P<0.05).Compared with LX-3,T-43 showed a longer root length and larger specific surface area,which is a strategy for adapting to changes in the nutrient environment.For the rice cultivar with high-NUE,the RSR was optimized by increasing the FRLD,root distribution in upper soil layers,and root endogenous hormones(IAA,Z+ZR)under suitable nitrogen conditions(N2).An efficient nutrient acquisition strategy can occur through root plasticity,leading to greater yield and NUE. 展开更多
关键词 drip irrigation rice nitrogen environment root traits PLASTICITY YIELD nitrogen use efficiency
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The Practical Logic and Optimization Path of Rural Human Settlement Environment Governance in Jiangsu Region of China from the Perspective of Cultural and Tourism Integration
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作者 Zhong Wei Jingyi Zhao +1 位作者 Yongshuai Zhang Yun Sun 《Proceedings of Business and Economic Studies》 2025年第1期119-126,共8页
In recent years,managing rural living environments has become a vital component of the rural revitalization strategy.Jiangsu Province,rich in economic and cultural resources,has accumulated valuable experience in expl... In recent years,managing rural living environments has become a vital component of the rural revitalization strategy.Jiangsu Province,rich in economic and cultural resources,has accumulated valuable experience in exploring rural environmental governance by integrating culture and tourism.This research analyzes the practical logic of rural environmental governance in Jiangsu from both theoretical and practical perspectives.It emphasizes the importance of integrating culture and tourism to enhance environmental governance while addressing the associated challenges.The results show that the integration of culture and tourism not only enhances rural ecological environments and living facilities but also boosts regional economic development and the preservation of cultural resources.Nevertheless,there are still challenges in aspects such as the collaboration of stakeholders,the establishment of long-term mechanisms,and the application of digital technologies.Based on real cases in Jiangsu,this study suggests optimization strategies and policy recommendations to improve rural environmental governance within the framework of cultural and tourism integration. 展开更多
关键词 Cultural and tourism integration Rural living environment Jiangsu Governance logic Optimization strategies
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Towards a Healthier Hospital Environment:The Role of Digital Twins in Achieving Optimal Environmental Comfort
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作者 Fabrizio Cumo Anna Maria Giovenale +1 位作者 Elisa Pennacchia Virginia Adele Tiburcio 《Digital Twins and Applications》 2025年第1期13-32,共20页
Indoor environmental comfort is fundamental to human health as people spend 90%of their time indoors.This aspect is even more crucial in hospitals,where the concept of health is closely linked to well-being,ethics and... Indoor environmental comfort is fundamental to human health as people spend 90%of their time indoors.This aspect is even more crucial in hospitals,where the concept of health is closely linked to well-being,ethics and environmental aspects.Emerging methodologies and technologies such as digital twin,building information modelling,the internet of things,sensing technologies and data analytics offer new opportunities to ensure healthier environments and more efficient building management.This paper provides an assessment of how digitalisation can support decision-making processes related to maintaining high levels of indoor environmental comfort in hospital settings,particularly by analysing how real-time data processing and the application of machine learning can promote proactive interventions in these facilities.The methodological approach was based on four phases:defining the objectives of the digital twin,identifying the input data to build and feed the digital model,defining the KPIs to evaluate the system's correct functioning and identifying the enabling technologies to be integrated into the system to achieve the set goal.The result is a digital twin for managing the operating room and its related services,with the aim of guiding decisions based on accurate data and improving operational efficiency,levels of environmental comfort,and safety regarding the diffusion of medical gases. 展开更多
关键词 building information modelling data analytics healthy indoor environment occupant building interaction occupant well-being
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Empowering Sentiment Analysis in Resource-Constrained Environments:Leveraging Lightweight Pre-trained Models for Optimal Performance
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作者 V.Prema V.Elavazhahan 《Journal of Harbin Institute of Technology(New Series)》 2025年第1期76-84,共9页
Sentiment analysis,a cornerstone of natural language processing,has witnessed remarkable advancements driven by deep learning models which demonstrated impressive accuracy in discerning sentiment from text across vari... Sentiment analysis,a cornerstone of natural language processing,has witnessed remarkable advancements driven by deep learning models which demonstrated impressive accuracy in discerning sentiment from text across various domains.However,the deployment of such models in resource-constrained environments presents a unique set of challenges that require innovative solutions.Resource-constrained environments encompass scenarios where computing resources,memory,and energy availability are restricted.To empower sentiment analysis in resource-constrained environments,we address the crucial need by leveraging lightweight pre-trained models.These models,derived from popular architectures such as DistilBERT,MobileBERT,ALBERT,TinyBERT,ELECTRA,and SqueezeBERT,offer a promising solution to the resource limitations imposed by these environments.By distilling the knowledge from larger models into smaller ones and employing various optimization techniques,these lightweight models aim to strike a balance between performance and resource efficiency.This paper endeavors to explore the performance of multiple lightweight pre-trained models in sentiment analysis tasks specific to such environments and provide insights into their viability for practical deployment. 展开更多
关键词 sentiment analysis light weight models resource⁃constrained environment pre⁃trained models
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Spatiotemporal evolution of ecological environment quality and its drivers in the Helan Mountain,China
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作者 HE Yuanrong CHEN Yuhang +5 位作者 ZHONG Liang LAI Yangfeng KANG Yuting LUO Ming ZHU Yunfei ZHANG Ming 《Journal of Arid Land》 2025年第2期224-244,共21页
Understanding the ecological evolution is of great significance in addressing the impacts of climate change and human activities.However,the ecological evolution and its drivers remain inadequately explored in arid an... Understanding the ecological evolution is of great significance in addressing the impacts of climate change and human activities.However,the ecological evolution and its drivers remain inadequately explored in arid and semi-arid areas.This study took the Helan Mountain,a typical arid and semi-arid area in China,as the study area.By adopting an Enhanced Remote Sensing Ecological Index(ERSEI)that integrates the habitat quality(HQ)index with the Remote Sensing Ecological Index(RSEI),we quantified the ecological environment quality of the Helan Mountain during 2010-2022 and analyzed the driving factors behind the changes.Principal Component Analysis(PCA)was used to validate the composite ERSEI,enabling the extraction of key features and the reduction of redundant information.The results showed that the contributions of first principal component(PC1)for ERSEI and RSEI were 80.23%and 78.72%,respectively,indicating that the ERSEI can provide higher precision and more details than the RSEI in assessing ecological environment quality.Temporally,the ERSEI in the Helan Mountain exhibited an initial decline followed by an increase from 2010 to 2022,with the average value of ERSEI ranging between 0.298 and 0.346.Spatially,the ERSEI showed a trend of being higher in the southwest and lower in the northeast,with high-quality ecological environments mainly concentrated in the western foothills at higher altitudes.The centroid of ERSEI shifted northeastward toward Helan County from 2010 to 2022.Temperature and digital elevation model(DEM)emerged as the primary drivers of ERSEI changes.This study highlights the necessity of using comprehensive monitoring tools to guide policy-making and conservation strategies,ensuring the resilience of fragile ecosystems in the face of ongoing climatic and anthropogenic pressures.The findings offer valuable insights for the sustainable management and conservation in arid and semi-arid ecosystems. 展开更多
关键词 ecological environment quality Enhanced Remote Sensing Ecological Index(ERSEI) Principal Component Analysis(PCA) Moran's I centroid migration analysis geographic detector(Geodetector) Helan Mountain
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Effects of thinning on the understory light environment of different stands and the photosynthetic performance and growth of the reforestation species Phoebe bournei 被引量:2
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作者 Shicheng Su Nianqing Jin Xiaoli Wei 《Journal of Forestry Research》 SCIE EI CAS CSCD 2024年第1期12-28,共17页
Light levels determine regeneration in stands and a key concern is how to regulate the light environment of different stand types to the requirements of the understory.In this study,we selected three stands typical in... Light levels determine regeneration in stands and a key concern is how to regulate the light environment of different stand types to the requirements of the understory.In this study,we selected three stands typical in south China(a Cryptomeria japonica plantation,a Quercus acutissima plantation,and a mixed stand of both)and three thinning intensities to determine the best understory light environ-ment for 3-year-old Phoebe bournei seedlings.The canopy structure,understory light environment,and photosynthe-sis and growth indicators were assessed following thin-ning.Thinning improved canopy structure and understory light availability of each stand;species composition was the reason for differences in the understory light environ-ment.Under the same thinning intensity,the mixed stand had the greatest light radiation and most balanced spectral composition.P.bournei photosynthesis and growth were closely related to the light environment;all three stands required heavy thinning to create an effective and sustained understory light environment.In a suitable understory light environment,the efficiency of light interception,absorption,and use by seedlings was enhanced,resulting in a higher carbon assimilation the main limiting factor was stomatal conductance.As a shade-avoidance signal,red/far-red radia-tion is a critical factor driving changes in photosynthesis and growth of P.bournei seedlings,and a reduction increased light absorption and use capacity and height:diameter ratios.The growth advantage transformed from diameter to height,enabling seedlings to access more light.Our findings suggest that the regeneration of shade-tolerant species such as P.bournei could be enhanced if a targeted approach to thinning based on stand type was adopted. 展开更多
关键词 THINNING Understory light environment Phoebe bournei Photosynthetic performance Growth performance
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Dry environment on the expression of lacrimal gland S100A9,Anxa1,and Clu in rats via proteomics 被引量:2
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作者 Yi-Lin Sun A-Yuan Cui +2 位作者 Li-Xin Wang Wang-Wang Zhang Hong Shi 《International Journal of Ophthalmology(English edition)》 SCIE CAS 2024年第3期435-443,共9页
●AIM:To investigate the underlying mechanism of dry environment(autumn dryness)affecting the lacrimal glands in rats.●METHODS:Twenty Sprague-Dawley rats were randomly divided into two groups.The rats were fed in spe... ●AIM:To investigate the underlying mechanism of dry environment(autumn dryness)affecting the lacrimal glands in rats.●METHODS:Twenty Sprague-Dawley rats were randomly divided into two groups.The rats were fed in specific pathogen free environment as the control group(n=10),and the rats fed in dry environment as the dryness group(n=10).After 24d,lacrimal glands were collected from the rats.The tissues morphology was observed by hematoxylineosin(HE)staining.Tandem mass tags(TMT)quantitative proteomics analysis technology was used to screen the differential expressed proteins of lacrimal glands between the two groups,then bioinformatics analysis was performed.Further,the immunohistochemical(IHC)method was used to verify the target proteins.●RESULTS:In dryness group,the lacrimal glands lobule atrophied,the glandular cavities enlarged,the sparse nuclear distribution and scattered inflammatory infiltration between the acinus were observed.The proteomics exhibited that a total of 195 up-regulated and 236 downregulated differential expressed proteins screened from the lacrimal glands of rats.It was indicated that the biological processes(BP)of differential expressed proteins mainly included cell processes and single BP.The cellular compositions of differential expressed proteins mainly located in cells,organelles.The molecular functions of differential expressed proteins mainly included binding,catalytic activity.Moreover,the Kyoto Encyclopedia of Genes and Genomes(KEGG)pathway analysis showed that the differential expressed proteins mainly involved lysosome,complement and coagulation cascade,and ribosome pathway.The IHC result verified that the up-regulated expression proteins of Protein S100A9(S100A9),Annexin A1(Anxa1),and Clusterin(Clu)in lacrimal glands of rats in dryness group were higher than control group.●CONCLUSION:The up-regulated expression proteins of S100A9,Anxa1,and Clu may be the potential mechanisms of dry eye symptoms caused by dry environment.This study provides clues of dry environments causing eye-related diseases for further studies. 展开更多
关键词 dry eye lacrimal gland S100A9 Clu Anxa1 environment RATS
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Study on Distribution of Four Pseudomonas Species in Living Environment Using Multiplex PCR 被引量:1
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作者 Sachiyo Hayashi Koji Umezawa +12 位作者 Osamu Tsuzukibashi Akira Fukatsu Mana Fuchigami Chiaki Komine Hiroshi Yamamoto Mio Hagiwara-Hamano Yukiko Iizuka Satoshi Uchibori Masanobu Wakami Hiroshi Murakami Taira Kobayashi Masahiko Fukumoto Takato Nomoto 《Open Journal of Stomatology》 2024年第2期77-86,共10页
Purpose: The genus Pseudomonas is a ubiquitous microorganism frequently detected from immunocompromised patients. The inherent resistance to numerous antimicrobial agents contributes to the opportunistic character of ... Purpose: The genus Pseudomonas is a ubiquitous microorganism frequently detected from immunocompromised patients. The inherent resistance to numerous antimicrobial agents contributes to the opportunistic character of this pathogen exhaustive monitoring of this pathogen is considered of critical importance to public health organizations. The reliable identification method able to distinguish genetic close Pseudomonas species is needed, because these organisms are difficult to differentiate by phenotypic or biochemical methods. The purpose of the present study was to design species-specific primers in order to identify and detect four Pseudomonas species which are frequently detected from the human oral cavities, and to investigate the distribution of these organisms in the living environment using a multiplex PCR. Methods: Polymerase chain reaction (PCR) primers were designed based on partial sequences of the rpoD gene of four Pseudomonas species. Swab samples were collected from fifty washstands, and the distribution of Pseudomonas species was investigated using a conventional PCR at genus level and a multiplex PCR at species level. Results: Multiplex PCR method developed in this study was able to distinguish four Pseudomonas species clearly. The genus Pseudomonas was detected from all samples (100%), whereas P. putida, P, aeruginosa, P. stutzeri and P. fluorescens were detected at 44%, 8%, 4% and 2% in fifty swab samples, respectively. Conclusion: Our developed one-step multiplex PCR method is accurate, specific, cost-effective, time-saving, and works without requiring DNA extraction. It was indicated that washstands were the uninhabitable environment for P. putida, P, aeruginosa, P. stutzeri and P. fluorescens. 展开更多
关键词 Genus Pseudomonas Multiplex PCR Living environment
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The corrosion characteristic and mechanism of Mg-5Y-1.5Nd-xZn-0.5Zr(x=0,2,4,6 wt.%)alloys in marine atmospheric environment 被引量:1
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作者 Quantong Jiang Dongzhu Lu +2 位作者 Liren Cheng Nazhen Liu Baorong Hou 《Journal of Magnesium and Alloys》 SCIE EI CAS CSCD 2024年第1期139-158,共20页
The microstructure and precipitated phases of as-cast Mg-5Y-1.5Nd-x Zn-0.5Zr(x=0,2,4,6 wt.%)alloys were investigated by optical microscopy,scanning electron microscopy,energy-dispersive spectrometry and X-ray Diffract... The microstructure and precipitated phases of as-cast Mg-5Y-1.5Nd-x Zn-0.5Zr(x=0,2,4,6 wt.%)alloys were investigated by optical microscopy,scanning electron microscopy,energy-dispersive spectrometry and X-ray Diffraction.The exposure corrosion experiment of these magnesium alloys was tested in South China Sea and KEXUE vessel atmospheric environment.The corrosion characteristic and mechanism of magnesium alloys of Mg-5Y-1.5Nd-x Zn-0.5Zr(x=0,2,4,6 wt.%)alloys were analyzed by weight loss rate,corrosion depth,corrosion products and corrosion morphologies.The electrochemical corrosion tests were also measured in the natural seawater.The comprehensive results showed that Mg-5Y-1.5Nd-4Zn-0.5Zr magnesium alloy existed the best corrosion resistance whether in the marine atmospheric environment and natural seawater environment.That depended on the microstructure,type and distribution of precipitated phases in Mg-5Y-1.5Nd-4Zn-0.5Zr magnesium alloy.Sufficient quantity anodic precipitated phases in the microstructure of Mg-5Y-1.5Nd-4Zn-0.5Zr alloy played the key role in the corrosion resistance. 展开更多
关键词 Marine atmospheric environment Exposure corrosion Magnesium alloy Corrosion rate Corrosion mechanism
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Paleoenvironmental Characteristics of Paleogene Lacustrine Source Rocks in the Western Bozhong Sag,Bohai Bay Basin,China:Evidence from Biomarkers,Major and Trace Elements 被引量:1
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作者 WANG Xiang LIU Guangdi +6 位作者 SONG Zezhang SUN Mingliang WANG Xiaolin WANG Feilong CHEN Rongtao GENG Mingyang LI Yishu 《Acta Geologica Sinica(English Edition)》 SCIE CAS CSCD 2024年第1期220-240,共21页
The organic matter(OM)enrichment mechanisms and depositional environment characteristics of lacustrine source rocks in the western Bozhong Sag,Bohai Bay Basin in Northeast China remain controversial.To address these i... The organic matter(OM)enrichment mechanisms and depositional environment characteristics of lacustrine source rocks in the western Bozhong Sag,Bohai Bay Basin in Northeast China remain controversial.To address these issues,based on Rock-Eval pyrolysis,kerogen macerals,H/C and O/C ratios,GC-MS,major and trace elements,the Dongying Formation Member(Mbr)3(E_(3)d_(3)),the Shahejie Formation mbrs 1 and 2(E_(2)s_(1+2)),and the Shahejie Mbr 3(E_(2)s_(3))source rocks in the western Bozhong Sag were studied.The above methods were used to reveal their geochemical properties,OM origins and depositional environments,all of which indicate that E_(2)s_(1+2)and E_(2)s_(3)are excellent source rocks,and that E_(3)d_(3)is of the second good quality.E_(3)d_(3)source rocks were formed under a warm and humid climate,mainly belong to fluvial/delta facies,the E_(3)d_(3)sediments formed under weakly oxidizing and freshwater conditions.Comparatively,the depositional environments of E_(2)s_(1+2)source rocks were arid and cold climate,representing saline or freshwater lacustrine facies,and the sediments of E_(2)s_(1+2)belong to anoxic or suboxic settings with large evaporation and salinity.During the period of E_(2)s_(3),the climate became warm and humid,indicating the freshwater lacustrine facies,and E_(2)s_(3)was characterized by freshwater and abundant algae.Moreover,compared with other intervals,the OM origin of E_(3)d_(3)source rocks has noticeable terrestrial input.The OM origin of the E_(2)s_(1+2)and E_(2)s_(3)are mainly plankton and bacteria.Tectonic subsidence and climate change have affected the changes of the depositional environment in the western Bozhong Sag,thus controlling the distribution of the source rocks,the geochemical characteristics in the three intervals of lacustrine source rocks have distinct differences.Overall,these factors are effective to evaluate the paleoenvironmental characteristics of source rocks by biomarkers,major and trace elements.The established models may have positive implications for research of lacustrine source rocks in offshore areas with few drillings. 展开更多
关键词 petroleum geology source rocks depositional environments biomarkers major elements trace elements Bozhong Sag
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Influence of static cartoons combined with dynamic virtual environments on preoperative anxiety of preschool-aged children undergoing surgery 被引量:2
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作者 Ya-Lin Zhang Qi-Ying Zhou +3 位作者 Peng Zhang Lin-Feng Huang Li Jin Zhi-Guo Zhou 《World Journal of Clinical Cases》 SCIE 2024年第22期4947-4955,共9页
BACKGROUND Preschoolers become anxious when they are about to undergo anesthesia and surgery,warranting the development of more appropriate and effective interventions.AIM To explore the effect of static cartoons comb... BACKGROUND Preschoolers become anxious when they are about to undergo anesthesia and surgery,warranting the development of more appropriate and effective interventions.AIM To explore the effect of static cartoons combined with dynamic virtual environments on preoperative anxiety and anesthesia induction compliance in preschool-aged children undergoing surgery.METHODS One hundred and sixteen preschool-aged children were selected and assigned to the drug(n=37),intervention(n=40),and control(n=39)groups.All the children received routine preoperative checkups and nursing before being transferred to the preoperative preparation room on the day of the operation.The drug group received 0.5 mg/kg midazolam and the intervention group treatment consisting of static cartoons combined with dynamic virtual environments.The control group received no intervention.The modified Yale Preoperative Anxiety Scale was used to evaluate the children’s anxiety level on the day before surgery(T0),before leaving the preoperative preparation room(T1),when entering the operating room(T2),and at anesthesia induction(T3).Compliance during anesthesia induction(T3)was evaluated using the Induction Compliance Checklist(ICC).Changes in mean arterial pressure(MAP),heart rate(HR),and respiratory rate(RR)were also recorded at each time point.RESULTS The anxiety scores of the three groups increased variously at T1 and T2.At T3,both the drug and intervention groups had similar anxiety scores,both of which were lower than those in the control group.At T1 and T2,MAP,HR,and RR of the three groups increased.The drug and control groups had significantly higher MAP and RR than the intervention group at T2.At T3,the MAP,HR,and RR of the drug group decreased and were significantly lower than those in the control group but were comparable to those in the intervention group.Both the drug and intervention groups had similar ICC scores and duration of anesthesia induction(T3),both of which were higher than those of the control group.CONCLUSION Combining static cartoons with dynamic virtual environments as effective as medication,specifically midazolam,in reducing preoperative anxiety and fear in preschool-aged children.This approach also improve their compliance during anesthesia induction and helped maintain their stable vital signs. 展开更多
关键词 PRESCHOOL Children Static cartoons combined with dynamic virtual environments Preoperative anxiety COMPLIANCE Anesthesia induction
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Corrosion behavior of HVOF Inconel 625 coating in the simulated marine environment 被引量:2
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作者 彭超 钟丰平 +2 位作者 袁梦 谢世杰 王学斌 《China Welding》 CAS 2024年第1期46-51,共6页
High velocity oxygen fuel(HVOF)spraying process is commonly used to produce superalloy coatings.Inconel 625 coating was prepared on Q235B low carbon steel by HVOF.A series of experiments were conducted to examine the ... High velocity oxygen fuel(HVOF)spraying process is commonly used to produce superalloy coatings.Inconel 625 coating was prepared on Q235B low carbon steel by HVOF.A series of experiments were conducted to examine the surface and corrosion resistance properties of Inconel 625 HVOF coating.In this paper,potentiodynamic polarization tests and electrochemical impedance spectroscopy(EIS)tests were carried out to evaluate the corrosion resistance of Inconel 625 coating under simulated marine environment.The experiment-al results showed that Inconel 625 coating revealed low porosity and desired coating thickness.Shift in the corrosion potential(E_(corr))to-wards the noble direction combined with much low corrosion current density(i_(corr))indicating a significant improvement of HVOF Inconel 625 coating compared with the substrate. 展开更多
关键词 high velocity oxygen fuel(HVOF) Inconel 625 coating marine environment corrosion
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The coordinated evolution of ecological environment,public service,and tourism economy along the Silk Road Economic Belt,using the Dual-Carbon Targets 被引量:1
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作者 Shuo Yang Wei Guo +1 位作者 Tianjun Xu Tongtong Liu 《Chinese Journal of Population,Resources and Environment》 2024年第1期34-47,共14页
Carbon peak and carbon neutrality(dual-carbon)are important targets for the international response to climate change.The Silk Road Economic Belt is a strategic resource region and is important for future ecological en... Carbon peak and carbon neutrality(dual-carbon)are important targets for the international response to climate change.The Silk Road Economic Belt is a strategic resource region and is important for future ecological environment and tourism development.Based on the“dual-carbon”targets,the Single index quantification,Multiple index synthesis,and Poly-criteria integration evaluation model were used in this study to measure the coordinated development index of the ecological environment,public service,and tourism economy along the Silk Road Economic Belt and to analyze its spatial and temporal evolution.Further,it explores the dynamic evolution and development trend of the three systems using the Kernel Density and Grey Markov Prediction Model.The results show that the coordinated development index along this region needs to be improved during the study period.Furthermore,the coordinated development index of the Southwest region is relatively higher than that of the Northwest region.From the development trend of the three systems,all of them develop in a stable manner;however,the tourism economy system is easily affected by external disturbances.The coordinated development index of the three systems changes dynamically and tends to be in a good state of coordination.There is a certain spatial and temporal heterogeneity.The gravity center of the coordinated development index has been in the Southwest region.During the forecast period,the coordinated development index along this region will improve significantly,while insufficient and unbalanced development will continue. 展开更多
关键词 Dual-carbon Ecological environment Public services Tourist economy Silk Road Economic Belt
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