Objective： The aim of our study was to compare the value of computed tomography （CT） and 99mTc-methylene- diphosphonate （MDP） SPECT （single photon emission computed tomography）/CT fusion imaging in determining ...Objective： The aim of our study was to compare the value of computed tomography （CT） and 99mTc-methylene- diphosphonate （MDP） SPECT （single photon emission computed tomography）/CT fusion imaging in determining the extent of mandibular invasion by malignant tumor of the oral cavity. Methods： This study had local ethical committee approval, and all patients gave written informed consent. Fifty-three patients were revealed mandibular invasion by malignant tumor of the oral cavity underwent CT and SPECT/CT. The patients were divided into two groups： group A （invasion-periphery-type） and group B （invasion-center- type）. Two radiologists assessed the CT images and two nuclear medicine physicians separately assessed the $PECT/CT images in consensus and without knowledge of the results of other imaging tests. The extent of bone involvement suggested with an imaging modality was compared with pathological findings in the surgical specimen. Results： With pathological findings as the standard of reference, Group A： The extent of mandibular invasion by malignant tumor under- went SPECT/CT was 1.02 _＋ 0.20 cm larger than that underwent pathological findings. And the extent of mandibular invasion underwent CT was 1.42 ＋ 0.35 cm smaller than that underwent pathological examination. There were significant difference among the three methods （P 〈 0.01）. Group B： The extent of mandibular invasion by malignant tumor underwent SPECT/CT was 1.3 ＋ 0.39 cm larger than that underwent pathological examination. The extent of mandibular invasion underwent CT was 2.55 ＋ 1.44 cm smaller than that underwent pathological findings. There were significant difference among the three methods （P 〈 0.01）. The extent of mandibular invasion underwent SPECT/CT was the extent which surgeon must excise to get clear margins. Conclusion： SPECT/CT fusion imaging has significant clinical value in determining the extent of mandibular inva- sion by malignant tumor of oral cavity.展开更多
Objective： The aim of the study was to evaluate the clinical value of ^99mTc-methylene diphosphonic acid （MDP） SPECT/CT fusion imaging and CT scanning in diagnosis of infiltrated mandible by gingival carcinoma. Met...Objective： The aim of the study was to evaluate the clinical value of ^99mTc-methylene diphosphonic acid （MDP） SPECT/CT fusion imaging and CT scanning in diagnosis of infiltrated mandible by gingival carcinoma. Methods： 18 cases of gingival carcinoma were processed infiltrated mandible by ^99mTc-MDP SPECT/CT fusion image and CT, and their scanning results compared with pathology findings. Results： Eleven of 13 cases with well-differentiated squamous cell carcinoma showed positive images, one of 11 cases was false positive images by pathology findings, and 10 cases were exhibited infiltrated mandibles; 5 cases with moderately differentiated and poorly differentiated squamous call carcinoma showed positive images, pathology showed carcinoma call had infiltrated cavum ossis of mandible. Five of 18 cases were positive images by CT. Conclusion： ^99mTc-MDP SPECT/CT fusion imaging is a useful method in diagnosis of infiltrated mandible by gingival carcinoma.展开更多
Objective: to analyze the application value of SPECT/CT fusion imaging technology in differential diagnosis of benign and malignant spinal lesions. Methods: all the subjects were diagnosed with SPECT/CT fusion imaging...Objective: to analyze the application value of SPECT/CT fusion imaging technology in differential diagnosis of benign and malignant spinal lesions. Methods: all the subjects were diagnosed with SPECT/CT fusion imaging technology, and then all the subjects were diagnosed with CT-guided percutaneous spinal biopsy. 42 cases of benign lesions were confirmed and 18 cases of malignant lesions, accounting for 70.00% and 30.00% respectively. Taking CT-guided biopsy as the gold standard, the detection rates of benign and malignant spinal lesions by SPECT/CT fusion imaging were statistically compared. Results: there was no significant difference between differential diagnosis accuracy and gold standard in SPECT/CT fusion imaging technique (P > 0.05). Conclusion: it has high differential diagnosis accuracy, can effectively identify patients' diseases, and is worthy of clinical application.展开更多
Objective: To explore the significance of dual-energy CT non-linear fusion technique in improving the quality of CTA image of renal cancer. Methods: The CTA images of 100 patients who had been confirmed by pathology a...Objective: To explore the significance of dual-energy CT non-linear fusion technique in improving the quality of CTA image of renal cancer. Methods: The CTA images of 100 patients who had been confirmed by pathology as renal cancer were collected and were randomly divided into experimental group and control group with 50 cases respectively. The two groups of patients were treated with iodine concentration of 300 mg/ml and 350 mg/ml non-ionic contrast agent, with a dosage of 1.5 ml/kg and an injection rate of 4 ml/s. The contrast agent intelligently tracking method was adopted bolus. The control group used the conventional CTA scanning, with a reference tube voltage/tube current of 100 kv/ref150 mas. The experimental group adopted the double energy scanning, with ball tube A and ball tube B. The reference tube voltage/tube current was 100 kv/ref250 mas and sn150 kv/ref125 mas respectively. The images of the experimental group were non-linear fused to obtain the Mono+ 55 kev single-energy images. The CT value, SNR contrast ratio of the abdominal aorta, renal artery and tumor tissue of the experimental group images and the 100 KV images and the Mono+ 55 kev images of the control group were compared. The objective evaluation and subjective evaluation of the image quality of the three groups of images was performed. Results: The results showed that the 100 kV images of the experimental group were statistically different from those of the control group (P05) in CT value, SNR and CNR (P 0.05). And there was no statistically significant difference between the non-linear fusion single-energy Mono+ 55 kev images and the control group images in CT value, SNR and CNR (P > 0.05). The subjective evaluation of image quality showed that there was no significant difference between Mono+ 55 kev images and control group images, and the quality of Mono+ 55 kev images was higher than that of experimental group 100 kV images. Conclusion: The dual-energy CT non-linear fusion technique can improve the quality of CTA image in patients with renal cancer, and it is possible to obtain high quality CTA images with low iodine concentration contrast agent.展开更多
目的探讨SPECT/CT融合图像与全身骨显像(whole-body bone scintigraphy,WBBS)对骨转移瘤的价值比较。方法回顾性分析我院80例可疑肿瘤骨转移性病变患者行WBBS及SPECT/CT断层图像融合,所有结果都通过病理或进一步随访等方式确诊。分别计...目的探讨SPECT/CT融合图像与全身骨显像(whole-body bone scintigraphy,WBBS)对骨转移瘤的价值比较。方法回顾性分析我院80例可疑肿瘤骨转移性病变患者行WBBS及SPECT/CT断层图像融合,所有结果都通过病理或进一步随访等方式确诊。分别计算并比较两种结果对病例及病灶诊断的灵敏度、特异度、阳性预测值、阴性预测值、正确诊断百分率。结果 80例患者骨转移61例,19例为良性病例,258处病灶中,骨转移202处,良性病灶为56处。WBBS对病例及病灶诊断的灵敏度分别为82%和89.1%,特异度分别为42.1%和31.7%,阳性预测值分别为82%和84.7%,阴性预测值分别为42.1%和40.6%,准确率72.5%和78.1%。SPECT/CT对病例及病灶诊断的灵敏度分别为98.4%和98%,特异度分别为52.6%和76.8%,阳性预测值分别为87%和93.8%,阴性预测值分别为90.9%和91.5%,准确率为87.5%和83.4%。两组数据均经过χ2检验,P<0.05。结论在骨转移瘤的诊断中,SPECT/CT融合图像较WBBS明显更具有诊断价值。展开更多
文摘Objective： The aim of our study was to compare the value of computed tomography （CT） and 99mTc-methylene- diphosphonate （MDP） SPECT （single photon emission computed tomography）/CT fusion imaging in determining the extent of mandibular invasion by malignant tumor of the oral cavity. Methods： This study had local ethical committee approval, and all patients gave written informed consent. Fifty-three patients were revealed mandibular invasion by malignant tumor of the oral cavity underwent CT and SPECT/CT. The patients were divided into two groups： group A （invasion-periphery-type） and group B （invasion-center- type）. Two radiologists assessed the CT images and two nuclear medicine physicians separately assessed the $PECT/CT images in consensus and without knowledge of the results of other imaging tests. The extent of bone involvement suggested with an imaging modality was compared with pathological findings in the surgical specimen. Results： With pathological findings as the standard of reference, Group A： The extent of mandibular invasion by malignant tumor under- went SPECT/CT was 1.02 _＋ 0.20 cm larger than that underwent pathological findings. And the extent of mandibular invasion underwent CT was 1.42 ＋ 0.35 cm smaller than that underwent pathological examination. There were significant difference among the three methods （P 〈 0.01）. Group B： The extent of mandibular invasion by malignant tumor underwent SPECT/CT was 1.3 ＋ 0.39 cm larger than that underwent pathological examination. The extent of mandibular invasion underwent CT was 2.55 ＋ 1.44 cm smaller than that underwent pathological findings. There were significant difference among the three methods （P 〈 0.01）. The extent of mandibular invasion underwent SPECT/CT was the extent which surgeon must excise to get clear margins. Conclusion： SPECT/CT fusion imaging has significant clinical value in determining the extent of mandibular inva- sion by malignant tumor of oral cavity.
文摘Objective： The aim of the study was to evaluate the clinical value of ^99mTc-methylene diphosphonic acid （MDP） SPECT/CT fusion imaging and CT scanning in diagnosis of infiltrated mandible by gingival carcinoma. Methods： 18 cases of gingival carcinoma were processed infiltrated mandible by ^99mTc-MDP SPECT/CT fusion image and CT, and their scanning results compared with pathology findings. Results： Eleven of 13 cases with well-differentiated squamous cell carcinoma showed positive images, one of 11 cases was false positive images by pathology findings, and 10 cases were exhibited infiltrated mandibles; 5 cases with moderately differentiated and poorly differentiated squamous call carcinoma showed positive images, pathology showed carcinoma call had infiltrated cavum ossis of mandible. Five of 18 cases were positive images by CT. Conclusion： ^99mTc-MDP SPECT/CT fusion imaging is a useful method in diagnosis of infiltrated mandible by gingival carcinoma.
文摘Objective: to analyze the application value of SPECT/CT fusion imaging technology in differential diagnosis of benign and malignant spinal lesions. Methods: all the subjects were diagnosed with SPECT/CT fusion imaging technology, and then all the subjects were diagnosed with CT-guided percutaneous spinal biopsy. 42 cases of benign lesions were confirmed and 18 cases of malignant lesions, accounting for 70.00% and 30.00% respectively. Taking CT-guided biopsy as the gold standard, the detection rates of benign and malignant spinal lesions by SPECT/CT fusion imaging were statistically compared. Results: there was no significant difference between differential diagnosis accuracy and gold standard in SPECT/CT fusion imaging technique (P > 0.05). Conclusion: it has high differential diagnosis accuracy, can effectively identify patients' diseases, and is worthy of clinical application.
文摘Objective: To explore the significance of dual-energy CT non-linear fusion technique in improving the quality of CTA image of renal cancer. Methods: The CTA images of 100 patients who had been confirmed by pathology as renal cancer were collected and were randomly divided into experimental group and control group with 50 cases respectively. The two groups of patients were treated with iodine concentration of 300 mg/ml and 350 mg/ml non-ionic contrast agent, with a dosage of 1.5 ml/kg and an injection rate of 4 ml/s. The contrast agent intelligently tracking method was adopted bolus. The control group used the conventional CTA scanning, with a reference tube voltage/tube current of 100 kv/ref150 mas. The experimental group adopted the double energy scanning, with ball tube A and ball tube B. The reference tube voltage/tube current was 100 kv/ref250 mas and sn150 kv/ref125 mas respectively. The images of the experimental group were non-linear fused to obtain the Mono+ 55 kev single-energy images. The CT value, SNR contrast ratio of the abdominal aorta, renal artery and tumor tissue of the experimental group images and the 100 KV images and the Mono+ 55 kev images of the control group were compared. The objective evaluation and subjective evaluation of the image quality of the three groups of images was performed. Results: The results showed that the 100 kV images of the experimental group were statistically different from those of the control group (P05) in CT value, SNR and CNR (P 0.05). And there was no statistically significant difference between the non-linear fusion single-energy Mono+ 55 kev images and the control group images in CT value, SNR and CNR (P > 0.05). The subjective evaluation of image quality showed that there was no significant difference between Mono+ 55 kev images and control group images, and the quality of Mono+ 55 kev images was higher than that of experimental group 100 kV images. Conclusion: The dual-energy CT non-linear fusion technique can improve the quality of CTA image in patients with renal cancer, and it is possible to obtain high quality CTA images with low iodine concentration contrast agent.
文摘目的探讨SPECT/CT融合图像与全身骨显像(whole-body bone scintigraphy,WBBS)对骨转移瘤的价值比较。方法回顾性分析我院80例可疑肿瘤骨转移性病变患者行WBBS及SPECT/CT断层图像融合,所有结果都通过病理或进一步随访等方式确诊。分别计算并比较两种结果对病例及病灶诊断的灵敏度、特异度、阳性预测值、阴性预测值、正确诊断百分率。结果 80例患者骨转移61例,19例为良性病例,258处病灶中,骨转移202处,良性病灶为56处。WBBS对病例及病灶诊断的灵敏度分别为82%和89.1%,特异度分别为42.1%和31.7%,阳性预测值分别为82%和84.7%,阴性预测值分别为42.1%和40.6%,准确率72.5%和78.1%。SPECT/CT对病例及病灶诊断的灵敏度分别为98.4%和98%,特异度分别为52.6%和76.8%,阳性预测值分别为87%和93.8%,阴性预测值分别为90.9%和91.5%,准确率为87.5%和83.4%。两组数据均经过χ2检验,P<0.05。结论在骨转移瘤的诊断中,SPECT/CT融合图像较WBBS明显更具有诊断价值。
