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Mechanism Study on the Effect of Retarder on Polyurethane Setting Time Based on Molecular Simulation
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作者 WU Yuxuan XU Wenyuan +1 位作者 YU Tianlai JI Yongcheng 《Journal of Wuhan University of Technology(Materials Science)》 SCIE EI CAS 2025年第1期224-231,共8页
This study identified castor oil and phosphate ester as effective retarders through setting time,tensile,and flexural tests,and determined their optimal dosages.The mechanism by which phosphate ester affects the setti... This study identified castor oil and phosphate ester as effective retarders through setting time,tensile,and flexural tests,and determined their optimal dosages.The mechanism by which phosphate ester affects the setting time of polyurethane was further investigated using molecular dynamics simulations.Fourier transform infrared spectroscopy was also employed to systematically study the physical and chemical interactions between phosphate esters and polyurethane materials.The results demonstrate that a 1%concentration of phosphate ester provides the most effective retarding effect with minimal impact on the strength of polyurethane.When phosphate ester is added to the B component of the two-component polyurethane system,its interaction energy with component A decreases,as do the diffusion coefficient and aggregation degree of component B on the surface of component A.This reduction in interaction slows the setting time.Additionally,the addition of phosphate ester to polyurethane leads to the disappearance or weakening of functional groups,indicating competitive interactions within the phosphate ester components that inhibit the reaction rate. 展开更多
关键词 POLYURETHANE RETARDER setting time molecular dynamics diffusion coefficient
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IoT Empowered Early Warning of Transmission Line Galloping Based on Integrated Optical Fiber Sensing and Weather Forecast Time Series Data
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作者 Zhe Li Yun Liang +1 位作者 Jinyu Wang Yang Gao 《Computers, Materials & Continua》 SCIE EI 2025年第1期1171-1192,共22页
Iced transmission line galloping poses a significant threat to the safety and reliability of power systems,leading directly to line tripping,disconnections,and power outages.Existing early warning methods of iced tran... Iced transmission line galloping poses a significant threat to the safety and reliability of power systems,leading directly to line tripping,disconnections,and power outages.Existing early warning methods of iced transmission line galloping suffer from issues such as reliance on a single data source,neglect of irregular time series,and lack of attention-based closed-loop feedback,resulting in high rates of missed and false alarms.To address these challenges,we propose an Internet of Things(IoT)empowered early warning method of transmission line galloping that integrates time series data from optical fiber sensing and weather forecast.Initially,the method applies a primary adaptive weighted fusion to the IoT empowered optical fiber real-time sensing data and weather forecast data,followed by a secondary fusion based on a Back Propagation(BP)neural network,and uses the K-medoids algorithm for clustering the fused data.Furthermore,an adaptive irregular time series perception adjustment module is introduced into the traditional Gated Recurrent Unit(GRU)network,and closed-loop feedback based on attentionmechanism is employed to update network parameters through gradient feedback of the loss function,enabling closed-loop training and time series data prediction of the GRU network model.Subsequently,considering various types of prediction data and the duration of icing,an iced transmission line galloping risk coefficient is established,and warnings are categorized based on this coefficient.Finally,using an IoT-driven realistic dataset of iced transmission line galloping,the effectiveness of the proposed method is validated through multi-dimensional simulation scenarios. 展开更多
关键词 Optical fiber sensing multi-source data fusion early warning of galloping time series data IOT adaptive weighted learning irregular time series perception closed-loop attention mechanism
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Epidemiological Aspects of Maternal Deaths Observed on Arrival over a Decade at the Fousseyni Daou Hospital in Kayes
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作者 Mahamadou Diassana Ballan Macalou +9 位作者 Sitapha Dembele Robert Diarra Alima Sidibe Lassina Goita Samou Diarra Seydou Z. Dao Mamadou Haidara Famakan Kane Fantamady Camara Soumaila Traore 《Open Journal of Obstetrics and Gynecology》 2025年第1期108-117,共10页
Introduction: The objective of this work was to study maternal deaths noted on arrival in the Gynecology and Obstetrics Department at Fousseyni Daou Hospital in Kayes over a period of 10 years. Materials and Methods: ... Introduction: The objective of this work was to study maternal deaths noted on arrival in the Gynecology and Obstetrics Department at Fousseyni Daou Hospital in Kayes over a period of 10 years. Materials and Methods: This was a cross-sectional, descriptive study with data collection over a period of 10 years;The data collection was retrospective over nine years from January 1, 2013 to December 31, 2021 and prospective over one year from January 1, 2022 to December 31, 2022. This study focused on all patients whose death was noted on arrival during pregnancy, labor or in the postpartum period in the Gynecology-Obstetrics Department of Fousseyni Daou Hospital. Confidentiality and anonymity were respected. The processing and analysis of statistical data were carried out using SPSS 20.0 software. Results: During the study period, we recorded 93 cases of death noted on arrival out of a total of 606 maternal deaths, i.e., a frequency of 15.34%. The average age was 27 years with the extremes of 20 years and 34 years. They came mainly from rural areas at 74%, were married at 82%, uneducated at 51.6%, housewives at 87.1%. The profession of the spouses is worker at 37.6%. In our sample, evacuated patients were the most represented with 75.3%. Postpartum hemorrhage was the most frequent reason for admission with 22.6%. The deceased patients had no medical history at 86%. In our series, 59.5% of the deceased patients had not had antenatal consultations (CPN). Patients who died on arrival and who had given birth at home were the most represented with 54.8%. Deaths from immediate postpartum hemorrhage complicated by shock were the most frequent with 25.8% followed by severe anemia 8.6%. Deaths were mainly due to direct obstetric causes at 76.3%. In these deaths observed on arrival, the 2nd delay was identified at 48.4%. Conclusion: Maternal deaths observed on arrival remain frequent in the Kayes region. The main causes are immediate postpartum hemorrhage and anemia, which are almost all preventable causes of maternal death following the 1st and 2nd delay. 展开更多
关键词 Death Observed on arrival Maternal Mortality Kayes Hospital
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Thermodynamic Energy-Laws Presuppose Time Orientation Subject to Principle of Least Action
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作者 Helmut Tributsch 《Journal of Modern Physics》 2025年第2期310-327,共18页
It is shown that time asymmetry is essential for deriving thermodynamic law and arises from the turnover of energy while reducing its information content and driving entropy increase. A dynamically interpreted princip... It is shown that time asymmetry is essential for deriving thermodynamic law and arises from the turnover of energy while reducing its information content and driving entropy increase. A dynamically interpreted principle of least action enables time asymmetry and time flow as a generation of action and redefines useful energy as an information system which implements a form of acting information. This is demonstrated using a basic formula, originally applied for time symmetry/energy conservation considerations, relating time asymmetry (which is conventionally denied but here expressly allowed), to energy behaviour. The results derived then explained that a dynamic energy is driving time asymmetry. It is doing it by decreasing the information content of useful energy, thus generating action and entropy increase, explaining action-time as an information phenomenon. Thermodynamic laws follow directly. The formalism derived readily explains what energy is, why it is conserved (1st law of thermodynamics), why entropy increases (2nd law) and that maximum entropy production within the restraints of the system controls self-organized processes of non-linear irreversible thermodynamics. The general significance of the principle of least action arises from its role of controlling the action generating oriented time of nature. These results contrast with present understanding of time neutrality and clock-time, which are here considered a source of paradoxes, intellectual contradictions and dead-end roads in models explaining nature and the universe. 展开更多
关键词 thermodynamic Laws Newton’s time Nature’s time Entropy Increase IRREVERSIBILITY SELF-ORGANIZatION Least Action
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Storage time affects the level and diagnostic efficacy of plasma biomarkers for neurodegenerative diseases
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作者 Lifang Zhao Mingkai Zhang +4 位作者 Qimeng Li Xuemin Wang Jie Lu Ying Han Yanning Cai 《Neural Regeneration Research》 SCIE CAS 2025年第8期2373-2381,共9页
Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is k... Several promising plasma biomarker proteins,such as amyloid-β(Aβ),tau,neurofilament light chain,and glial fibrillary acidic protein,are widely used for the diagnosis of neurodegenerative diseases.However,little is known about the long-term stability of these biomarker proteins in plasma samples stored at-80°C.We aimed to explore how storage time would affect the diagnostic accuracy of these biomarkers using a large cohort.Plasma samples from 229 cognitively unimpaired individuals,encompassing healthy controls and those experiencing subjective cognitive decline,as well as 99 patients with cognitive impairment,comprising those with mild cognitive impairment and dementia,were acquired from the Sino Longitudinal Study on Cognitive Decline project.These samples were stored at-80°C for up to 6 years before being used in this study.Our results showed that plasma levels of Aβ42,Aβ40,neurofilament light chain,and glial fibrillary acidic protein were not significantly correlated with sample storage time.However,the level of total tau showed a negative correlation with sample storage time.Notably,in individuals without cognitive impairment,plasma levels of total protein and tau phosphorylated protein threonine 181(p-tau181)also showed a negative correlation with sample storage time.This was not observed in individuals with cognitive impairment.Consequently,we speculate that the diagnostic accuracy of plasma p-tau181 and the p-tau181 to total tau ratio may be influenced by sample storage time.Therefore,caution is advised when using these plasma biomarkers for the identification of neurodegenerative diseases,such as Alzheimer's disease.Furthermore,in cohort studies,it is important to consider the impact of storage time on the overall results. 展开更多
关键词 Alzheimer’s disease amyloid-β diagnostic ability glial fibrillary acidic protein NEURODEGENERatION neurofilament light chain plasma biomarkers single molecule array storage time tau
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Impact of the chaotic semiconductor laser output power on time-delay-signature of chaos and random bit generation
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作者 Chenpeng Xue Xu Wang +3 位作者 Likai Zheng Haoyu Zhang Yanhua Hong Zuxing Zhang 《Chinese Physics B》 2025年第3期325-330,共6页
We experimentally analyze the effect of the optical power on the time delay signature identification and the random bit generation in chaotic semiconductor laser with optical feedback.Due to the inevitable noise durin... We experimentally analyze the effect of the optical power on the time delay signature identification and the random bit generation in chaotic semiconductor laser with optical feedback.Due to the inevitable noise during the photoelectric detection and analog-digital conversion,the varying of output optical power would change the signal to noise ratio,then impact time delay signature identification and the random bit generation.Our results show that,when the optical power is less than-14 dBm,with the decreasing of the optical power,the actual identified time delay signature degrades and the entropy of the chaotic signal increases.Moreover,the extracted random bit sequence with lower optical power is more easily pass through the randomness testing. 展开更多
关键词 CHAOS time delay signature entropy estimation random bit generation
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Detection and interpretation of the time-varying seasonal signals in China with multi-geodetic measurements
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作者 Liansheng Deng Yugang Xiao +4 位作者 Qusen Chen Wei Peng Zhao Li Hua Chen Zhiwen Wu 《Geodesy and Geodynamics》 2025年第1期42-54,共13页
The time-varying periodic variations in Global Navigation Satellite System(GNSS)stations affect the reliable time series analysis and appropriate geophysical interpretation.In this study,we apply the singular spectrum... The time-varying periodic variations in Global Navigation Satellite System(GNSS)stations affect the reliable time series analysis and appropriate geophysical interpretation.In this study,we apply the singular spectrum analysis(SSA)method to characterize and interpret the periodic patterns of GNSS deformations in China using multiple geodetic datasets.These include 23-year observations from the Crustal Movement Observation Network of China(CMONOC),displacements inferred from the Gravity Recovery and Climate Experiment(GRACE),and loadings derived from Geophysical models(GM).The results reveal that all CMONOC time series exhibit seasonal signals characterized by amplitude and phase modulations,and the SSA method outperforms the traditional least squares fitting(LSF)method in extracting and interpreting the time-varying seasonal signals from the original time series.The decrease in the root mean square(RMS)correlates well with the annual cycle variance estimated by the SSA method,and the average reduction in noise amplitudes is nearly twice as much for SSA filtered results compared with those from the LSF method.With SSA analysis,the time-varying seasonal signals for all the selected stations can be identified in the reconstructed components corresponding to the first ten eigenvalues.Moreover,both RMS reduction and correlation analysis imply the advantages of GRACE solutions in explaining the GNSS periodic variations,and the geophysical effects can account for 71%of the GNSS annual amplitudes,and the average RMS reduction is 15%.The SSA method has proved to be useful for investigating the GNSS timevarying seasonal signals.It could be applicable as an auxiliary tool in the improvement of nonlinear variations investigations. 展开更多
关键词 GNSS coordinate time series Singularspectrumanalysis time-varying seasonal signals Loading effects GRACE
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Cyclic loading of marble:Correlating the attenuation of the electric and acoustic activities and highlighting criticality indices in terms of natural time
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作者 Dimos Triantis Ilias Stavrakas +1 位作者 Ermioni D.Pasiou Stavros K.Kourkoulis 《International Journal of Mining Science and Technology》 2025年第2期159-174,共16页
The attenuation of the acoustic activity in marble specimens under uniaxial compressive loadingunloading loops is quantified in juxtaposition to that of the electric activity.In parallel,the existence of"pre-fail... The attenuation of the acoustic activity in marble specimens under uniaxial compressive loadingunloading loops is quantified in juxtaposition to that of the electric activity.In parallel,the existence of"pre-failure indiceso"warning about entrance into a critical stage,that of impending fracture,is explored.The acoustic activity is quantified in terms of the normalized number of acoustic hits,their average rate of production and their cumulative energy,and,the cumulative counts and their average rate of change.The electric activity is studied in terms of the pressure stimulated currents and the electric charge released.The analysis revealed that the acoustic and electric activities are linearly correlated to each other,suggesting that they are different manifestations of the same damage mechanisms.In addition,Kaiser's effect,governing the acoustic activity,is found to govern,also,the electric activity.Moreover,it is concluded that entrance into the critical stage is safely predicted by means of a simple criterion,based on the evolution of the average rate of change of the normalized cumulative counts in the natural time domain.These predictions are almost identical with those of the criterion based on the "varianceo" and the "entropies" of the time series of acoustic events in this domain. 展开更多
关键词 Marble cyclic loading Acoustic emissions Kaiser's effect Pressure stimulated currents Criticality indices Natural time
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Exploring the impact of mobile device use on mealtime distractions and its consequences for metabolic health:A narrative minireview
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作者 Muhammad Shahzad Aslam 《World Journal of Clinical Cases》 2025年第17期7-15,共9页
The habitual use of smartphones during meals has become a common behavior,raising concerns about its potential impact on eating habits and metabolic health.The present narrative review investigates how using a smartph... The habitual use of smartphones during meals has become a common behavior,raising concerns about its potential impact on eating habits and metabolic health.The present narrative review investigates how using a smartphone or tablet during meals can cause distractions and negatively affect metabolic health.A comprehensive narrative review was conducted by synthesizing peer-reviewed studies on the interplay between smartphone use during meals,eating behaviors,and metabolic health.Relevant literature was identified through searches in electronic databases and organized thematically to highlight trends and research gaps.By synthesizing evidence from existing literature,this review highlights that smartphone use during meals is associated with increased caloric intake,altered food composition,and disruptions in postprandial metabolic responses.These effects are mediated by reduced meal awareness and psychological distractions,including multitasking.Variability in findings arises from differences in study designs and populations.This review identifies critical research gaps,including the lack of longitudinal studies and the need to explore mechanisms underlying these relationships.By summarizing trends and patterns,this narrative review offers valuable insights into the complex interplay between digital device use,eating habits,and metabolic health,providing a foundation for future research and interventions. 展开更多
关键词 Digital devices Smartphone usage Mealtime behavior Eating habits Postprandial glucose Screen time Dietary patterns Metabolic responses Technological distractions Mobile health
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Study on the pattern of train arrival headway time in high-speed railway
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作者 Changhai Tian Shoushuai Zhang 《Railway Sciences》 2024年第3期344-366,共23页
Purpose-The design goal for the tracking interval of high-speed railway trains in China is 3 min,but it is difficult to achieve,and it is widely believed that it is mainly limited by the tracking interval of train arr... Purpose-The design goal for the tracking interval of high-speed railway trains in China is 3 min,but it is difficult to achieve,and it is widely believed that it is mainly limited by the tracking interval of train arrivals.If the train arrival tracking interval can be compressed,it will be beneficial for China's high-speed railway to achieve a 3-min train tracking interval.The goal of this article is to study how to compress the train arrival tracking interval.Design/methodologylapproach-By simulating the process of dense train groups arriving at the station and stopping,the headway between train arrivals at the station was calculated,and the pattern of train arrival headway was obtained,changing the traditional understanding that the train arrival headway is considered the main factor limiting the headway of trains.Findings-When the running speed of trains is high,the headway between trains is short,the length of the station approach throat area is considerable and frequent train arrivals at the station,the arrival headway for the first group or several groups of trains will exceed the headway,but the subsequent sets of trains will havea headway equal to the arrival headway.This convergence characteristic is obtained by appropriately increasing the running time.Originality/value-According to this pattern,there is no need to overly emphasize the impact of train arrival headway on the headway.This plays an important role in compressing train headway and improving high-speedrailwaycapacity. 展开更多
关键词 High speed railway Train headway Train arrival headway Regular pattern Paper type Research paper
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Riding the Trend of the Times with a Strong Sense of Responsibility
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作者 Wang Yi 《China International Studies》 2025年第1期5-20,共16页
In 2024,the world witnessed further transformation and instability,marked by protracted and intensified geopolitical conflicts,repeated attempts to decouple and sever supply chains,and the rapid rise of the Global Sou... In 2024,the world witnessed further transformation and instability,marked by protracted and intensified geopolitical conflicts,repeated attempts to decouple and sever supply chains,and the rapid rise of the Global South.It has become all the more clear where the once-in-a-century transformations are heading.In 2024,China acted on the blueprint drawn up at the Third Plenary Session of the 20th Central Committee of the Communist Party of China(CPC),and made big strides in deepening reform comprehensively.Marking the 75th anniversary of the founding of New China,China carried forward its great cause of national development and pressed ahead with Chinese modernization with vigor and determination. 展开更多
关键词 STRONG timeS DEEPENING
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The Finite Volume Element Method for Time-Fractional Nonlinear Fourth-Order Diffusion Equation with Time Delay
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作者 Anran Li Qing Yang 《Engineering(科研)》 2025年第1期53-72,共20页
In this article, a finite volume element algorithm is presented and discussed for the numerical solutions of a time-fractional nonlinear fourth-order diffusion equation with time delay. By choosing the second-order sp... In this article, a finite volume element algorithm is presented and discussed for the numerical solutions of a time-fractional nonlinear fourth-order diffusion equation with time delay. By choosing the second-order spatial derivative of the original unknown as an additional variable, the fourth-order problem is transformed into a second-order system. Then the fully discrete finite volume element scheme is formulated by using L1approximation for temporal Caputo derivative and finite volume element method in spatial direction. The unique solvability and stable result of the proposed scheme are proved. A priori estimate of L2-norm with optimal order of convergence O(h2+τ2−α)where τand hare time step length and space mesh parameter, respectively, is obtained. The efficiency of the scheme is supported by some numerical experiments. 展开更多
关键词 time-Fractional Nonlinear Fourth-Order Diffusion Equation with time Delay Finite Volume Element Method Caputo-Fractional Derivative Optimal Priori Error Analysis
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Countability of Infinite Paths in the Infinity Tree: Proof of the Continuum Hypothesis in a Non-Cantorian Infinity Theory
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作者 Philip C. Jackson 《Advances in Pure Mathematics》 2025年第1期73-90,共18页
A previous paper showed that the real numbers between 0 and 1 could be represented by an infinite tree structure, called the ‘infinity tree’, which contains only a countably infinite number of nodes and arcs. This p... A previous paper showed that the real numbers between 0 and 1 could be represented by an infinite tree structure, called the ‘infinity tree’, which contains only a countably infinite number of nodes and arcs. This paper discusses how a finite-state Turing machine could, in a countably infinite number of state transitions, write all the infinite paths in the infinity tree to a countably infinite tape. Hence it is argued that the real numbers in the interval [0, 1] are countably infinite in a non-Cantorian theory of infinity based on Turing machines using countably infinite space and time. In this theory, Cantor’s Continuum Hypothesis can also be proved. And in this theory, it follows that the power set of the natural numbers P(ℕ) is countably infinite, which contradicts the claim of Cantor’s Theorem for the natural numbers. However, this paper does not claim there is an error in Cantor’s arguments that [0, 1] is uncountably infinite. Rather, this paper considers the situation as a paradox, resulting from different choices about how to represent and count the continuum of real numbers. 展开更多
关键词 INFINITY Countable UNCOUNTABLE Diagonalization Real Numbers Infinity Tree Continuum Hypothesis Turing Machine Infinite time Turing Machine Non-Cantorian
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The Clinical Significance of the Emergency Green Channel in the Treatment of Patients with Acute Chest Pain
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作者 Congying Li Yi Zhang 《Journal of Clinical and Nursing Research》 2025年第1期113-119,共7页
Objective: To analyze the clinical significance of the emergency green channel in the treatment of patients with acute chest pain. Methods: Sixty patients with acute chest pain treated between September 2022 and July ... Objective: To analyze the clinical significance of the emergency green channel in the treatment of patients with acute chest pain. Methods: Sixty patients with acute chest pain treated between September 2022 and July 2024 were selected as the subjects of this study. They were divided into groups based on the order of treatment: the first 30 patients were included in the Green Channel group, where the emergency green channel was employed, while the remaining 30 patients were placed in the Regular Emergency group, receiving standard emergency treatment. The rescue time, hospitalization time, pain scores, incidence of adverse reactions, and quality of life between the Green Channel group and the Regular Emergency group were compared. Results: The rescue time and hospitalization time of the Green Channel group were shorter than those of the Regular Emergency group, with statistical significance (P < 0.05). The pain scores at 30, 60, 120, and 240 minutes after rescue in the Green Channel group were lower than those in the Regular Emergency group, with statistical significance (P < 0.05). The incidence of adverse reactions such as recurrent acute attacks, arrhythmia, heart failure, stroke, and shock in the Green Channel group was lower than that in the Regular Emergency group, with statistical significance (P < 0.05). The treatment satisfaction rate and success rate in the Green Channel group were 93.33% and 93.33%, respectively, while those in the Regular Emergency group were 73.33% and 73.33%. Both the satisfaction and success rates in the Green Channel group were higher than those in the Regular Emergency group, with statistical significance (P < 0.05). The quality of life in the Green Channel group was also higher than that in the Regular Emergency group, with statistical significance (P < 0.05). Conclusion: The emergency green channel plays a significant role in the treatment of patients with acute chest pain and is worthy of widespread clinical application. 展开更多
关键词 Emergency green channel Patients with acute chest pain Rescue time Hospitalization time Pain score Incidence of adverse reactions
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The burden of upper motor neuron involvement is correlated with the bilateral limb involvement interval in patients with amyotrophic lateral sclerosis:a retrospective observational study
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作者 Jieying Wu Shan Ye +2 位作者 Xiangyi Liu Yingsheng Xu Dongsheng Fan 《Neural Regeneration Research》 SCIE CAS 2025年第5期1505-1512,共8页
Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor neurons.Early bilateral limb involvement significantly affects patients'daily lives ... Amyotrophic lateral sclerosis is a rare neurodegenerative disease characterized by the involvement of both upper and lower motor neurons.Early bilateral limb involvement significantly affects patients'daily lives and may lead them to be confined to bed.However,the effect of upper and lower motor neuron impairment and other risk factors on bilateral limb involvement is unclear.To address this issue,we retrospectively collected data from 586 amyotrophic lateral sclerosis patients with limb onset diagnosed at Peking University Third Hospital between January 2020 and May 2022.A univariate analysis revealed no significant differences in the time intervals of spread in different directions between individuals with upper motor neuron-dominant amyotrophic lateral sclerosis and those with classic amyotrophic lateral sclerosis.We used causal directed acyclic graphs for risk factor determination and Cox proportional hazards models to investigate the association between the duration of bilateral limb involvement and clinical baseline characteristics in amyotrophic lateral sclerosis patients.Multiple factor analyses revealed that higher upper motor neuron scores(hazard ratio[HR]=1.05,95%confidence interval[CI]=1.01–1.09,P=0.018),onset in the left limb(HR=0.72,95%CI=0.58–0.89,P=0.002),and a horizontal pattern of progression(HR=0.46,95%CI=0.37–0.58,P<0.001)were risk factors for a shorter interval until bilateral limb involvement.The results demonstrated that a greater degree of upper motor neuron involvement might cause contralateral limb involvement to progress more quickly in limb-onset amyotrophic lateral sclerosis patients.These findings may improve the management of amyotrophic lateral sclerosis patients with limb onset and the prediction of patient prognosis. 展开更多
关键词 amyotrophic lateral sclerosis bilateral limb involvement Cox proportional hazards regression model horizontal spread restricted cubic spline analysis time interval upper motor neuron vertical spread
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Impacts of increasing compound hot-dry events on vegetation under the warming-wetting trend in Northwest China
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作者 Zejin Liu Limin Jiao Xihong Lian 《Geography and Sustainability》 2025年第2期32-43,共12页
In a warming world,climate extremes tend to be more frequent and intense.The exceptional response of ecosystems triggered by extreme climate events under a warmer and wetter climate in northwest China(NWC)has aroused ... In a warming world,climate extremes tend to be more frequent and intense.The exceptional response of ecosystems triggered by extreme climate events under a warmer and wetter climate in northwest China(NWC)has aroused growing concern.However,understanding the responses of vegetation to climate extremes from the compound events perspective remains challenging.In this study,we identify the climate dynamics in NWC during 1971–2020 based on daily meteorological observations,focusing on the changes in compound hot-dry events(CHDEs)during the warmer and wetter period.We further explore the effects of CHDEs on vegetation by examining vegetation anomalies and recovery time using daily gross primary productivity(GPP)data.The results show a clear warmer and wetter period in NWC during 2000–2020.No signs of a hiatus in CHDEs increase are observed during this period,and even the duration of CHDEs in western NWC keeps showing an increasing tendency.Vegetation in eastern NWC,with a lower probability of GPP anomalies,exhibits stronger resistance of ecosystems to CHDEs than in western NWC.In NWC,vegetation typically returns to its normal state in 5.50 days on average,but exhibits greater resilience in the western region,where it takes less recovery time(4.82 days).Vegetation in the central region shows the lowest probability of GPP anomalies and relatively longer recovery time,likely due to its higher altitudes.Our research underscores the imperative to address the considerable impacts of CHDEs on vegetation growth even as the regional climate becomes increasingly warmer and wetter. 展开更多
关键词 Warming-wetting trend Compound hot-dry events Vegetation anomaly Recovery time
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Two FT genes synergistically regulate the reproductive transition of loquat
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作者 Yuanyuan Jiang Yunmei Zhu +9 位作者 Ze Peng Wenbing Su Jiangrong Peng Yuan Yuan Ling Zhang Zhike Zhang Xianghui Yang Yongshun Gao Shunquan Lin Chongjian Ma 《Horticultural Plant Journal》 2025年第2期548-563,共16页
Unlike annual flowering plants that exhibit a single reproductive cycle encompassing vegetative growth,flowering,and senescence within a single year,perennial woody trees undergo a transition between vegetative and re... Unlike annual flowering plants that exhibit a single reproductive cycle encompassing vegetative growth,flowering,and senescence within a single year,perennial woody trees undergo a transition between vegetative and reproductive growth every year after a long juvenile phase.Most woody fruit trees bloom when it turns warm in spring,and the fruit ripens in summer or autumn.However,as a member of the Maloideae subfamily,the loquat tree blooms in the cold autumn and winter,and the fruit matures in the spring.To explore the regulatory mechanism of loquat flowering,we characterized two FLOWERING LOCUS T homologous genes in loquat,EjFT1 and EjFT2.qRT-PCR results revealed that EjFT1 and EjFT2 exhibited nearly opposite expression patterns in various tissues.EjFT1 was mainly expressed in young tissues;EjFT2 was mainly expressed in mature leaves,open flowers,and fruits.EjFT2 exhibited an obvious circadian rhythm and was regulated by EjCO.After the trees were exposed to short-day conditions or sprayed with exogenous GA_(3),the expression of EjFT2 was strongly inhibited,and the loquat tree did not produce floral buds.Furthermore,the yeast two-hybrid,bimolecular fluorescence complementation,and Dualluciferase assay experiments revealed that both EjFT1 and EjFT2 interacted with EjFD,with the EjFT2-EjFD protein complex enhancing the activity of EjAP1-1 and EjAP1-2 promoters,while EjFT1-EjFD inhibited the activity of the EjAP1-1 promoter.Protein structural analysis of EjFT1and EjFT2 suggested that differences in amino acid residues at Val_(123)/Leu_(123),Ser_(157)/Ala_(157),and Val_(158)/Ala_(158)may be the reason for their functional differences.Our results showed that EjFT1 and EjFT2 may cooperatively regulate the floral bud differentiation of loquat by competitively binding with EjFD.EjFT2 regulates the onset of loquat floral bud differentiation by responding to photoperiod and gibberellin signals,while EjFT1 is involved in the vegetative growth of loquat.These findings provide important clues for the investigation of the regulatory mechanism of loquat flowering and advance the exploration into the multiple roles of FT homologous genes in regulating the reproductive transformation and vegetative growth of flowering plants. 展开更多
关键词 LOQUat Flowering time GA3 Short day FT AP1
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LONG TIME EXISTENCE FOR THE NON-ISENTROPIC SLIGHTLY COMPRESSIBLE FLUID MODEL OF KORTEWEG TYPE
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作者 Qiangchang JU Jianjun XU 《Acta Mathematica Scientia》 2025年第2期416-445,共30页
We investigate the long time existence of strong solutions to the initial value problem for the three-dimensional non-isentropic compressible Navier-Stokes-Korteweg system.Under the conditions of slight density and te... We investigate the long time existence of strong solutions to the initial value problem for the three-dimensional non-isentropic compressible Navier-Stokes-Korteweg system.Under the conditions of slight density and temperature variations,we verify that the full compressible Navier-Stokes-Korteweg equations admit a unique strong solution as long as the solution of the limiting system exists,when the Mach number is sufficiently small.Furthermore,we deduce the uniform convergence of strong solutions for the compressible system toward those for the corresponding incompressible system on the time interval in which the solution exists. 展开更多
关键词 non-isentropic compressible Navier-Stokes-Korteweg equations low Mach num-ber limit long time existence strong solution
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Shortening the recipient warm ischemia time could be a strategy for expanding the liver donor pool
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作者 Jia-Wei Yu Lin-Biao Xiang +11 位作者 Xiao-Juan Dong Chen-Xi Yang Lei Wang Xiao-Yu Liu Yi-Hong Song Xian-Jie Bai Jing-Wen Xiao Lu Ren Qin-Hong Xu Gang-Hua Yang Yi Lv Qiang Lu 《World Journal of Gastroenterology》 2025年第9期135-145,共11页
BACKGROUND Shortening the recipient warm ischemia time(rWIT)has been proven to be effective for improving the short-and long-term outcomes after liver transplantation(LT)and offsets the negative impact of an extended ... BACKGROUND Shortening the recipient warm ischemia time(rWIT)has been proven to be effective for improving the short-and long-term outcomes after liver transplantation(LT)and offsets the negative impact of an extended cold ischemia time.However,few studies have been conducted to explore the prognostic effects of shortening the rWIT in transplantations using a liver graft from an extendedcriteria donor(ECD).AIM To investigate whether shortening the rWIT could improve the outcomes of ECD LT.METHODS Rat ECD autologous orthotopic LT were performed with variable rWITs(0,10,20,and 30 minutes).Near-infrared fluorescence imaging(FI)was used for the real-time assessment of liver graft ischemia-reperfusion injury after the anhepatic phase.Survival was assessed,and liver function and histological analyses were performed on the third day after transplantation.RESULTS The FI curve growth rate and postoperative three-day survival rate significantly increased,and the liver function and Suzuki score of the liver grafts significantly improved when the rWIT was≤10 minutes(P<0.05).CONCLUSION The post-transplant outcomes were significantly better with a shorter rWIT(10 minutes or less)than with a longer rWIT,which could be a strategy for expanding the liver donor pool. 展开更多
关键词 Extended criteria donor Recipient warm ischemia time Autologous orthotopic liver transplantation Near-infrared fluorescence imaging Outcome
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Calculation of the carrier dynamics and impedance spectroscopy model in quantum well infrared photodetectors
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作者 Chenzhe Hu Yuyu Bu +2 位作者 Xianying Dai Fengqiu Jiang Yue Hao 《Journal of Semiconductors》 2025年第3期89-95,共7页
Quantum well infrared photodetectors(QWIPs) based on intersubband transitions hold significant potential for high bandwidth operation. In this work, we establish a carrier transport optimization model incorporating el... Quantum well infrared photodetectors(QWIPs) based on intersubband transitions hold significant potential for high bandwidth operation. In this work, we establish a carrier transport optimization model incorporating electron injection at the emitter to investigate the carrier dynamics time and impedance spectroscopy in GaAs/AlGaAs QWIPs. Our findings provide novel evidence that the escape time of electrons is the key limiting factor for the 3-dB bandwidth of QWIPs. Moreover, to characterize the impact of carrier dynamics time and non-equilibrium space charge region on impedance, we developed an equivalent circuit model where depletion region resistance and capacitance are employed to describe non-equilibrium space charge region. Using this model, we discovered that under illumination, both net charge accumulation caused by variations in carrier dynamics times within quantum wells and changes in width of non-equilibrium space charge region exert different dominant influences on depletion region capacitance at various doping concentrations. 展开更多
关键词 quantum well infrared photodetectors(QWIPs) carrier dynamics time impedance spectroscopy equivalent circuit model 3-dB bandwidth
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