Antimicrobial resistance is a global public health threat,and the World Health Organization(WHO)has announced a priority list of the most threatening pathogens against which novel antibiotics need to be developed.The ...Antimicrobial resistance is a global public health threat,and the World Health Organization(WHO)has announced a priority list of the most threatening pathogens against which novel antibiotics need to be developed.The discovery and introduction of novel antibiotics are time-consuming and expensive.According to WHO’s report of antibacterial agents in clinical development,only 18 novel antibiotics have been approved since 2014.Therefore,novel antibiotics are critically needed.Artificial intelligence(AI)has been rapidly applied to drug development since its recent technical breakthrough and has dramatically improved the efficiency of the discovery of novel antibiotics.Here,we first summarized recently marketed novel antibiotics,and antibiotic candidates in clinical development.In addition,we systematically reviewed the involvement of AI in antibacterial drug development and utilization,including small molecules,antimicrobial peptides,phage therapy,essential oils,as well as resistance mechanism prediction,and antibiotic stewardship.展开更多
The automotive sector is crucial in modern society,facilitating essential transportation needs across personal,commercial,and logistical domains while significantly contributing to national economic development and em...The automotive sector is crucial in modern society,facilitating essential transportation needs across personal,commercial,and logistical domains while significantly contributing to national economic development and employment generation.The transformative impact of Artificial Intelligence(AI)has revolutionised multiple facets of the automotive industry,encompassing intelligent manufacturing processes,diagnostic systems,control mechanisms,supply chain operations,customer service platforms,and traffic management solutions.While extensive research exists on the above aspects of AI applications in automotive contexts,there is a compelling need to synthesise this knowledge comprehensively to guide and inspire future research.This review introduces a novel taxonomic framework that provides a holistic perspective on AI integration into the automotive sector,focusing on next-generation AI methods and their critical implementation aspects.Additionally,the proposed conceptual framework for real-time condition monitoring of electric vehicle subsystems delivers actionable maintenance recommendations to stakeholders,addressing a critical gap in the field.The review highlights that AI has significantly expedited the development of autonomous vehicles regarding navigation,decision-making,and safety features through the use of advanced algorithms and deep learning structures.Furthermore,it identifies advanced driver assistance systems,vehicle health monitoring,and predictive maintenance as the most impactful AI applications,transforming operational safety and maintenance efficiency in modern automotive technologies.The work is beneficial to understanding the various use cases of AI in the different automotive domains,where AI maintains a state-of-the-art for sector-specific applications,providing a strong foundation for meeting Industry 4.0 needs and encouraging AI use among more nascent industry segments.The current work is intended to consolidate previous works while shedding some light on future research directions in promoting further growth of AI-based innovations in the scope of automotive applications.展开更多
Artificial intelligence(AI)has significantly transformed higher education by enabling personalized learning through adaptive platforms,intelligent tutoring systems,and real-time feedback mechanisms.This study ex-amine...Artificial intelligence(AI)has significantly transformed higher education by enabling personalized learning through adaptive platforms,intelligent tutoring systems,and real-time feedback mechanisms.This study ex-amines the benefits and challenges of AI-driven personalized learning,emphasizing its potential to improve student engagement,retention,and academic outcomes.However,ethical concerns—such as data privacy,al-gorithmic bias,and access disparities—pose challenges that must be addressed for sustainable AI integration.By analyzing case studies from multiple universities and synthesizing existing literature,this research proposes a framework for ethical AI implementation that balances innovation with accountability and inclusivity.The findings contribute to ongoing discussions on AI’s role in education,providing practical insights for educators,administrators,and policymakers.展开更多
Cognitive computing has emerged as a transformative force in artificial intelligence(AI)education,bridging theoretical advancements with practical applications.This article explores the role of cognitive models in en-...Cognitive computing has emerged as a transformative force in artificial intelligence(AI)education,bridging theoretical advancements with practical applications.This article explores the role of cognitive models in en-hancing learning systems,from intelligent tutoring and personalized recommendations to virtual laboratories and special education support.It examines key technologies—such as knowledge graphs,natural language processing,and multimodal data analysis—that enable adaptive,human-like responsiveness.The study also ad-dresses technical challenges like interpretability and data privacy,alongside ethical concerns including equity and bias.Looking forward,it discusses how cognitive computing could reshape future learning modalities and aligns with trends like artificial general intelligence and interdisciplinary learning science.By tracing the path from theory to practice,this work underscores the potential of cognitive computing to create an inclusive,dy-namic educational landscape,while highlighting the need for ethical and technical rigor to ensure its responsible evolution.展开更多
With the rapid development of technology,artificial intelligence(AI)is increasingly being applied in various fields.In today’s context of resource scarcity,pursuit of sustainable development and resource reuse,the tr...With the rapid development of technology,artificial intelligence(AI)is increasingly being applied in various fields.In today’s context of resource scarcity,pursuit of sustainable development and resource reuse,the transformation of old objects is particularly important.This article analyzes the current status of old object transformation and the opportunities brought by the internet to old objects and delves into the application of artificial intelligence in old object transformation.The focus is on five aspects:intelligent identification and classification,intelligent evaluation and prediction,automation integration,intelligent design and optimization,and integration of 3D printing technology.Finally,the process of“redesigning an old furniture,such as a wooden desk,through AI technology”is described,including the recycling,identification,detection,design,transformation,and final user feedback of the old wooden desk.This illustrates the unlimited potential of the“AI+old object transformation”approach,advocates for people to strengthen green environmental protection,and drives sustainable development.展开更多
Cardiovascular diseases are the leading cause of death,requiring innovative approaches for prevention,diagnosis,and treatment.Personalized medicine customizes interventions according to individual characteristics,with...Cardiovascular diseases are the leading cause of death,requiring innovative approaches for prevention,diagnosis,and treatment.Personalized medicine customizes interventions according to individual characteristics,with artificial intelligence(AI)playing a key role in analyzing complex data to improve diagnostic accuracy,predict outcomes,and optimize therapies.AI can identify patterns in imaging and biomarkers,facilitating the earlier detection of medical conditions.Wearable devices and health applications facilitate continuous monitoring and personalized care.Emerging fields such as digital Chinese medicine offer additional perspectives by integrating traditional diagnostic principles with modern digital tools,contributing to holistic and individualized cardiovascular care.This study examines the advancements and challenges in personalized cardiovascular medicine,highlighting the need to address issues such as data privacy,algorithmic bias,and accessibility to promote the equitable application of personalized medicine.展开更多
In view of the common problems of integrating artificial intelligence into the training of postgraduates in Acupuncture and Tuina major,this paper reviews the related research progress both at home and abroad.It puts ...In view of the common problems of integrating artificial intelligence into the training of postgraduates in Acupuncture and Tuina major,this paper reviews the related research progress both at home and abroad.It puts forward the innovative reform paths for integrating artificial intelligence into postgraduate training mode of Acupuncture and Tuina major:construct the teaching staff of artificial intelligence graduate students;innovating artificial intelligence to promote the integration of classics and scientific research;constructing the ideological and political case base of artificial intelligence courses;implementing artificial intelligence platform blended teaching;building a domestic and foreign exchange platform for artificial intelligence.Through practical research in teaching,it has achieved good teaching results and played a good demonstration,leading and radiation role in similar majors in China.展开更多
文章探讨了医学检索中对话式AI机器人的设计原则,基于Scopus与Web of Science平台的多源案例,分析其层次架构,探索模型中的深度学习与自然语言处理、上下文语境及个性化推荐等特征,解析对话式AI机器人在医学检索中的机遇与挑战以及对我...文章探讨了医学检索中对话式AI机器人的设计原则,基于Scopus与Web of Science平台的多源案例,分析其层次架构,探索模型中的深度学习与自然语言处理、上下文语境及个性化推荐等特征,解析对话式AI机器人在医学检索中的机遇与挑战以及对我国的启示,为我国“新医科”建设提供借鉴与参考。展开更多
In this work,we have developed a novel machine(deep)learning computational framework to determine and identify damage loading parameters(conditions)for structures and materials based on the permanent or residual plast...In this work,we have developed a novel machine(deep)learning computational framework to determine and identify damage loading parameters(conditions)for structures and materials based on the permanent or residual plastic deformation distribution or damage state of the structure.We have shown that the developed machine learning algorithm can accurately and(practically)uniquely identify both prior static as well as impact loading conditions in an inverse manner,based on the residual plastic strain and plastic deformation as forensic signatures.The paper presents the detailed machine learning algorithm,data acquisition and learning processes,and validation/verification examples.This development may have significant impacts on forensic material analysis and structure failure analysis,and it provides a powerful tool for material and structure forensic diagnosis,determination,and identification of damage loading conditions in accidental failure events,such as car crashes and infrastructure or building structure collapses.展开更多
In 2023,pivotal advancements in artificial intelligence(AI)have significantly experienced.With that in mind,traditional methodologies,notably the p-y approach,have struggled to accurately model the complex,nonlinear s...In 2023,pivotal advancements in artificial intelligence(AI)have significantly experienced.With that in mind,traditional methodologies,notably the p-y approach,have struggled to accurately model the complex,nonlinear soil-structure interactions of laterally loaded large-diameter drilled shafts.This study undertakes a rigorous evaluation of machine learning(ML)and deep learning(DL)techniques,offering a comprehensive review of their application in addressing this geotechnical challenge.A thorough review and comparative analysis have been carried out to investigate various AI models such as artificial neural networks(ANNs),relevance vector machines(RVMs),and least squares support vector machines(LSSVMs).It was found that despite ML approaches outperforming classic methods in predicting the lateral behavior of piles,their‘black box'nature and reliance only on a data-driven approach made their results showcase statistical robustness rather than clear geotechnical insights,a fact underscored by the mathematical equations derived from these studies.Furthermore,the research identified a gap in the availability of drilled shaft datasets,limiting the extendibility of current findings to large-diameter piles.An extensive dataset,compiled from a series of lateral loading tests on free-head drilled shaft with varying properties and geometries,was introduced to bridge this gap.The paper concluded with a direction for future research,proposes the integration of physics-informed neural networks(PINNs),combining data-driven models with fundamental geotechnical principles to improve both the interpretability and predictive accuracy of AI applications in geotechnical engineering,marking a novel contribution to the field.展开更多
基金supported by the National Natural Science Foundation of China(32300157)the Shanghai Municipal Science and Technology Commission(19411964900)+1 种基金the Major Research and Development Project of Innovative Drugs,Ministry of Science and Technology of China(2017ZX09304005)the Wellcome Trust.
文摘Antimicrobial resistance is a global public health threat,and the World Health Organization(WHO)has announced a priority list of the most threatening pathogens against which novel antibiotics need to be developed.The discovery and introduction of novel antibiotics are time-consuming and expensive.According to WHO’s report of antibacterial agents in clinical development,only 18 novel antibiotics have been approved since 2014.Therefore,novel antibiotics are critically needed.Artificial intelligence(AI)has been rapidly applied to drug development since its recent technical breakthrough and has dramatically improved the efficiency of the discovery of novel antibiotics.Here,we first summarized recently marketed novel antibiotics,and antibiotic candidates in clinical development.In addition,we systematically reviewed the involvement of AI in antibacterial drug development and utilization,including small molecules,antimicrobial peptides,phage therapy,essential oils,as well as resistance mechanism prediction,and antibiotic stewardship.
基金The authors are grateful to the Universiti Malaysia Pahang Al-Sultan Abdullah and the Malaysian Ministry of Higher Education for their generous support and funding provided through University Distinguished Research Grants(Project No.RDU223016)as well as financial assistance provided through the Fundamental Research Grant Scheme(No.FRGS/1/2022/TK10/UMP/02/35).
文摘The automotive sector is crucial in modern society,facilitating essential transportation needs across personal,commercial,and logistical domains while significantly contributing to national economic development and employment generation.The transformative impact of Artificial Intelligence(AI)has revolutionised multiple facets of the automotive industry,encompassing intelligent manufacturing processes,diagnostic systems,control mechanisms,supply chain operations,customer service platforms,and traffic management solutions.While extensive research exists on the above aspects of AI applications in automotive contexts,there is a compelling need to synthesise this knowledge comprehensively to guide and inspire future research.This review introduces a novel taxonomic framework that provides a holistic perspective on AI integration into the automotive sector,focusing on next-generation AI methods and their critical implementation aspects.Additionally,the proposed conceptual framework for real-time condition monitoring of electric vehicle subsystems delivers actionable maintenance recommendations to stakeholders,addressing a critical gap in the field.The review highlights that AI has significantly expedited the development of autonomous vehicles regarding navigation,decision-making,and safety features through the use of advanced algorithms and deep learning structures.Furthermore,it identifies advanced driver assistance systems,vehicle health monitoring,and predictive maintenance as the most impactful AI applications,transforming operational safety and maintenance efficiency in modern automotive technologies.The work is beneficial to understanding the various use cases of AI in the different automotive domains,where AI maintains a state-of-the-art for sector-specific applications,providing a strong foundation for meeting Industry 4.0 needs and encouraging AI use among more nascent industry segments.The current work is intended to consolidate previous works while shedding some light on future research directions in promoting further growth of AI-based innovations in the scope of automotive applications.
文摘Artificial intelligence(AI)has significantly transformed higher education by enabling personalized learning through adaptive platforms,intelligent tutoring systems,and real-time feedback mechanisms.This study ex-amines the benefits and challenges of AI-driven personalized learning,emphasizing its potential to improve student engagement,retention,and academic outcomes.However,ethical concerns—such as data privacy,al-gorithmic bias,and access disparities—pose challenges that must be addressed for sustainable AI integration.By analyzing case studies from multiple universities and synthesizing existing literature,this research proposes a framework for ethical AI implementation that balances innovation with accountability and inclusivity.The findings contribute to ongoing discussions on AI’s role in education,providing practical insights for educators,administrators,and policymakers.
文摘Cognitive computing has emerged as a transformative force in artificial intelligence(AI)education,bridging theoretical advancements with practical applications.This article explores the role of cognitive models in en-hancing learning systems,from intelligent tutoring and personalized recommendations to virtual laboratories and special education support.It examines key technologies—such as knowledge graphs,natural language processing,and multimodal data analysis—that enable adaptive,human-like responsiveness.The study also ad-dresses technical challenges like interpretability and data privacy,alongside ethical concerns including equity and bias.Looking forward,it discusses how cognitive computing could reshape future learning modalities and aligns with trends like artificial general intelligence and interdisciplinary learning science.By tracing the path from theory to practice,this work underscores the potential of cognitive computing to create an inclusive,dy-namic educational landscape,while highlighting the need for ethical and technical rigor to ensure its responsible evolution.
基金2023 College Student Innovation and Entrepreneurship Training Program-Provincial and Ministerial Level(Chongqing City):Jiangjiang-A DIY Old Object Transformation Platform Integrating AI Technology(Project No.:S202312608036)。
文摘With the rapid development of technology,artificial intelligence(AI)is increasingly being applied in various fields.In today’s context of resource scarcity,pursuit of sustainable development and resource reuse,the transformation of old objects is particularly important.This article analyzes the current status of old object transformation and the opportunities brought by the internet to old objects and delves into the application of artificial intelligence in old object transformation.The focus is on five aspects:intelligent identification and classification,intelligent evaluation and prediction,automation integration,intelligent design and optimization,and integration of 3D printing technology.Finally,the process of“redesigning an old furniture,such as a wooden desk,through AI technology”is described,including the recycling,identification,detection,design,transformation,and final user feedback of the old wooden desk.This illustrates the unlimited potential of the“AI+old object transformation”approach,advocates for people to strengthen green environmental protection,and drives sustainable development.
文摘Cardiovascular diseases are the leading cause of death,requiring innovative approaches for prevention,diagnosis,and treatment.Personalized medicine customizes interventions according to individual characteristics,with artificial intelligence(AI)playing a key role in analyzing complex data to improve diagnostic accuracy,predict outcomes,and optimize therapies.AI can identify patterns in imaging and biomarkers,facilitating the earlier detection of medical conditions.Wearable devices and health applications facilitate continuous monitoring and personalized care.Emerging fields such as digital Chinese medicine offer additional perspectives by integrating traditional diagnostic principles with modern digital tools,contributing to holistic and individualized cardiovascular care.This study examines the advancements and challenges in personalized cardiovascular medicine,highlighting the need to address issues such as data privacy,algorithmic bias,and accessibility to promote the equitable application of personalized medicine.
基金Supported by Research Project of Postgraduate Education and Teaching Reform in Jilin Province in 2023(JJKH20230060YJG)Research Project of Teaching Reform of Vocational Education and Adult Education in Jilin Province(2022ZCY295)+5 种基金Scientific Research Project of Higher Education in Jilin Province in 2023(JGJX2023D200)Research Project of Teaching Reform of Higher Education in 2023(XJSX202301)Research Project of Teaching Reform of Higher Education in 2023(XJ202303)Postgraduate Training Innovation Demonstration Project in 2023(2023YJ04)Postgraduate Training Innovation Demonstration Project in 2023(2023YJ01)Provincial College Students Innovation and Entrepreneurship Project(S202310199042&S202310199043).
文摘In view of the common problems of integrating artificial intelligence into the training of postgraduates in Acupuncture and Tuina major,this paper reviews the related research progress both at home and abroad.It puts forward the innovative reform paths for integrating artificial intelligence into postgraduate training mode of Acupuncture and Tuina major:construct the teaching staff of artificial intelligence graduate students;innovating artificial intelligence to promote the integration of classics and scientific research;constructing the ideological and political case base of artificial intelligence courses;implementing artificial intelligence platform blended teaching;building a domestic and foreign exchange platform for artificial intelligence.Through practical research in teaching,it has achieved good teaching results and played a good demonstration,leading and radiation role in similar majors in China.
文摘In this work,we have developed a novel machine(deep)learning computational framework to determine and identify damage loading parameters(conditions)for structures and materials based on the permanent or residual plastic deformation distribution or damage state of the structure.We have shown that the developed machine learning algorithm can accurately and(practically)uniquely identify both prior static as well as impact loading conditions in an inverse manner,based on the residual plastic strain and plastic deformation as forensic signatures.The paper presents the detailed machine learning algorithm,data acquisition and learning processes,and validation/verification examples.This development may have significant impacts on forensic material analysis and structure failure analysis,and it provides a powerful tool for material and structure forensic diagnosis,determination,and identification of damage loading conditions in accidental failure events,such as car crashes and infrastructure or building structure collapses.
基金supported by Prince Sultan University(Grant No.PSU-CE-TECH-135,2023).
文摘In 2023,pivotal advancements in artificial intelligence(AI)have significantly experienced.With that in mind,traditional methodologies,notably the p-y approach,have struggled to accurately model the complex,nonlinear soil-structure interactions of laterally loaded large-diameter drilled shafts.This study undertakes a rigorous evaluation of machine learning(ML)and deep learning(DL)techniques,offering a comprehensive review of their application in addressing this geotechnical challenge.A thorough review and comparative analysis have been carried out to investigate various AI models such as artificial neural networks(ANNs),relevance vector machines(RVMs),and least squares support vector machines(LSSVMs).It was found that despite ML approaches outperforming classic methods in predicting the lateral behavior of piles,their‘black box'nature and reliance only on a data-driven approach made their results showcase statistical robustness rather than clear geotechnical insights,a fact underscored by the mathematical equations derived from these studies.Furthermore,the research identified a gap in the availability of drilled shaft datasets,limiting the extendibility of current findings to large-diameter piles.An extensive dataset,compiled from a series of lateral loading tests on free-head drilled shaft with varying properties and geometries,was introduced to bridge this gap.The paper concluded with a direction for future research,proposes the integration of physics-informed neural networks(PINNs),combining data-driven models with fundamental geotechnical principles to improve both the interpretability and predictive accuracy of AI applications in geotechnical engineering,marking a novel contribution to the field.
