In the second language teaching class,language is not only the teaching media,but also the teaching content.Thus,intermediate language plays a vital role in the teaching effect in the second language class.Based on th...In the second language teaching class,language is not only the teaching media,but also the teaching content.Thus,intermediate language plays a vital role in the teaching effect in the second language class.Based on the analysis of the application of English as an intermediate language in international education,the writer put forward some suggestions on how to use the intermediate language effectively,hoping to provide some help and enlightenment to the teaching of Chinese as a foreign language,so as to achieve the effect of twice the result with half the effort.展开更多
The phase III clinical trial of the novel molecular targeted agent(MTA)lenvatinib for patients with advanced hepatocellular carcinoma(HCC)(REFLECT trial)found that lenvatinib was non-inferior to sorafenib in overall s...The phase III clinical trial of the novel molecular targeted agent(MTA)lenvatinib for patients with advanced hepatocellular carcinoma(HCC)(REFLECT trial)found that lenvatinib was non-inferior to sorafenib in overall survival.Recently,the efficacy of multiple MTAs,including lenvatinib,in practice has been reported,and therapeutic strategies for Barcelona Clinic Liver Cancer(BCLC)intermediate stage HCC are undergoing major changes.Based on these results,lenvatinib could be recommended for patients with transcatheter arterial chemoembolization(TACE)-refractory,ALBI grade 1,within the up-to-seven criteria in the BCLC intermediate stage.Lenvatinib provides a more favorable outcome than TACE,even in cases with large or multinodular HCC beyond the up-to-seven criteria with Child-Pugh grade A.When patients meet the definitions of TACE-refractory or TACE-unsuitable,switching to systemic chemotherapy,including lenvatinib,is for favorable for preserving liver function.If initial treatment,including MTA,has a significant therapeutic effect and downstaging of HCC is obtained,additional TACE or surgical resection should be considered.Lenvatinib also has a therapeutic effect for poorly differentiated type and non-simple nodular type HCC thanks to the survival-prolonging effect of this drug.Furthermore,a significant therapeutic effect is expected in tumors with more than 50%liver involvement or main portal vein invasion,which have traditionally been considered to have a poor prognosis in patients.This suggests that at the start of lenvatinib treatment,HCC patients with ALBI grade 1 may be able to maintain liver functional reserve.展开更多
The indicator of social financing scale(SFS)has become a new intermediate target for China’s socioeconomic regulation since 2011,which has a better tracking performance on important economic indicators such as CPI an...The indicator of social financing scale(SFS)has become a new intermediate target for China’s socioeconomic regulation since 2011,which has a better tracking performance on important economic indicators such as CPI and is also the new intermediate target of monetary policy used by China’s central bank to replace M2 at present.So,is there an impact of the social financing scale on another important economic indicator,the RMB exchange rate?This paper conducted an OLS regression analysis of the time series data of social financing scale and the nominal effective exchange rate(NEER)of RMB for a total of 61 months from October 2016 to October 2021 and find that SFS has a significant positive impact on the exchange rate of RMB.This result means that the expansion of SFS will lead to the appreciation of RMB.In addition,the paper fills the research gap on the combination of SFS and RMB exchange rate,and suggests that mechanisms such as monetary policy or domestic interest rates may be responsible for this correlation at the theoretical level.展开更多
文摘In the second language teaching class,language is not only the teaching media,but also the teaching content.Thus,intermediate language plays a vital role in the teaching effect in the second language class.Based on the analysis of the application of English as an intermediate language in international education,the writer put forward some suggestions on how to use the intermediate language effectively,hoping to provide some help and enlightenment to the teaching of Chinese as a foreign language,so as to achieve the effect of twice the result with half the effort.
文摘The phase III clinical trial of the novel molecular targeted agent(MTA)lenvatinib for patients with advanced hepatocellular carcinoma(HCC)(REFLECT trial)found that lenvatinib was non-inferior to sorafenib in overall survival.Recently,the efficacy of multiple MTAs,including lenvatinib,in practice has been reported,and therapeutic strategies for Barcelona Clinic Liver Cancer(BCLC)intermediate stage HCC are undergoing major changes.Based on these results,lenvatinib could be recommended for patients with transcatheter arterial chemoembolization(TACE)-refractory,ALBI grade 1,within the up-to-seven criteria in the BCLC intermediate stage.Lenvatinib provides a more favorable outcome than TACE,even in cases with large or multinodular HCC beyond the up-to-seven criteria with Child-Pugh grade A.When patients meet the definitions of TACE-refractory or TACE-unsuitable,switching to systemic chemotherapy,including lenvatinib,is for favorable for preserving liver function.If initial treatment,including MTA,has a significant therapeutic effect and downstaging of HCC is obtained,additional TACE or surgical resection should be considered.Lenvatinib also has a therapeutic effect for poorly differentiated type and non-simple nodular type HCC thanks to the survival-prolonging effect of this drug.Furthermore,a significant therapeutic effect is expected in tumors with more than 50%liver involvement or main portal vein invasion,which have traditionally been considered to have a poor prognosis in patients.This suggests that at the start of lenvatinib treatment,HCC patients with ALBI grade 1 may be able to maintain liver functional reserve.
文摘The indicator of social financing scale(SFS)has become a new intermediate target for China’s socioeconomic regulation since 2011,which has a better tracking performance on important economic indicators such as CPI and is also the new intermediate target of monetary policy used by China’s central bank to replace M2 at present.So,is there an impact of the social financing scale on another important economic indicator,the RMB exchange rate?This paper conducted an OLS regression analysis of the time series data of social financing scale and the nominal effective exchange rate(NEER)of RMB for a total of 61 months from October 2016 to October 2021 and find that SFS has a significant positive impact on the exchange rate of RMB.This result means that the expansion of SFS will lead to the appreciation of RMB.In addition,the paper fills the research gap on the combination of SFS and RMB exchange rate,and suggests that mechanisms such as monetary policy or domestic interest rates may be responsible for this correlation at the theoretical level.
