Background: Vegetation distribution maps are of great significance for nature protection and management. In diverse tropical forests, accurate spatial mapping of vegetation types is challenging;the high species divers...Background: Vegetation distribution maps are of great significance for nature protection and management. In diverse tropical forests, accurate spatial mapping of vegetation types is challenging;the high species diversity and abundance of rare species challenge classification concepts, while remote sensing signals may not vary systematically with species composition, complicating the technical capability for delineating vegetation types in the landscape.Methods: We used a combination of field-based compositional data and their relations to environmental variables to predict the distribution of forest types in the Wuzhishan National Natural Reserve(WNNR), Hainan Island,China, using multivariate regression trees(MRT). The MRT was based on arboreal vegetation composition in 132plots of 20 m×20 m with a regular spacing of 1 km. Apart from the MRT, non-metric multidimensional scaling(NMDS) was used to evaluate vegetation-environment relationships.Results: The MRT model worked best when using 14 key environmental variables including topography, climate,latitude and soil, although the difference with the simpler model including only topographical variables was small. The full model classified the 132 plots into 3 vegetation types, 6 formation groups, 20 formations and 65associations at different hierarchical syntaxonomic levels. This model was the basis for forest vegetation maps for the WNNR. MRT and NMDS showed that elevation was the main driving force for the distribution of vegetation types and formation groups. Climate, latitude, and soil(especially available P), together with topographic variables, all influenced the distribution of formations and associations.Conclusions: While elevation determines forest-type distributions, lower-level syntaxonomic forest classes respond to the topographic diversity typical for mountains. Apart from providing the first detailed forest vegetation map for any part of WNNR, we show how, in spite of limitations, MRT with existing environmental data can be a useful method for mapping diverse and remote tropical forests.展开更多
Recent technological advancements and developments have led to a dramatic increase in the amount of high-dimensional data and thus have increased the demand for proper and efficient multivariate regression methods.Num...Recent technological advancements and developments have led to a dramatic increase in the amount of high-dimensional data and thus have increased the demand for proper and efficient multivariate regression methods.Numerous traditional multivariate approaches such as principal component analysis have been used broadly in various research areas,including investment analysis,image identification,and population genetic structure analysis.However,these common approaches have the limitations of ignoring the correlations between responses and a low variable selection efficiency.Therefore,in this article,we introduce the reduced rank regression method and its extensions,sparse reduced rank regression and subspace assisted regression with row sparsity,which hold potential to meet the above demands and thus improve the interpretability of regression models.We conducted a simulation study to evaluate their performance and compared them with several other variable selection methods.For different application scenarios,we also provide selection suggestions based on predictive ability and variable selection accuracy.Finally,to demonstrate the practical value of these methods in the field of microbiome research,we applied our chosen method to real population-level microbiome data,the results of which validated our method.Our method extensions provide valuable guidelines for future omics research,especially with respect to multivariate regression,and could pave the way for novel discoveries in microbiome and related research fields.展开更多
Objective: To determine the independent prognostic factors in the recurrence of colonic carcinoma after curative resection. Methods: Two hundred and one patients undergoing curative resections for colonic carcinoma we...Objective: To determine the independent prognostic factors in the recurrence of colonic carcinoma after curative resection. Methods: Two hundred and one patients undergoing curative resections for colonic carcinoma were investigated by univariate and Cox multivariate regression analyses. Ten factors contributed to the rate were analyzed. Results: Dukes stages, obstruction, postoperative chemotherapy as well as the growth manner of the tumor were significantly associated with the recurrence rate of colonic carcinoma (P<0.05) by univariate analysis, while Dukes stages, obstruction, and postoperative chemotherapy were significant factors by the multivariate analysis. Conclusion: Dukes stages, obstruction, and postoperative chemotherapy are independent prognostic factors in the recurrence of colonic carcinoma.展开更多
Often many variables have to be analyzed for their importance in terms of significant contribution and predictability in medical research. One of the possible analytical tools may be the Multiple Linear Regression Ana...Often many variables have to be analyzed for their importance in terms of significant contribution and predictability in medical research. One of the possible analytical tools may be the Multiple Linear Regression Analysis. However, research papers usually report both univariate and multivariate regression analyses of the data. The biostatistician sometimes faces practical difficulties while selecting the independent variables for logical inclusion in the multivariate analysis. The selection criteria for inclusion of a variable in the multivariate regression is that the variable at the univariate level should have a regression coefficient with p 〈 0.20. However, there is a chance that an independent variable with p 〉 0.20 at univariate regression may become significant in the multivariate regression analysis and vice versa, provided the above criteria is not strictly adhered to. We undertook both univariate and multivariate linear regression analyses on data from two multi-centric clinical trials. We recommend that there is no need to restrict the p value of 〈= 0.20. Because of high speed computer and availability of statistical software, the desired results could be achieved by considering all relevant independent variables in multivariate regression analysis.展开更多
Abstract Using the method of stepwise multivariate linear regression (SMLR), the quantitative structure activity relationships (QSAR) of two isomeric series of taxol and its derivatives have been studied. It was foun...Abstract Using the method of stepwise multivariate linear regression (SMLR), the quantitative structure activity relationships (QSAR) of two isomeric series of taxol and its derivatives have been studied. It was found that the molar refractivity of the C3′substituent of the C13 side chain has significant correlation with its activity. We deduce that structural changes in the C3′substituents may be critical to the anticancer function. It would be useful to the design and synthesis of taxol like compounds with improved activities.展开更多
Piles are long, slender structural elements used to transfer the loads from the superstructure through weak strata onto stiffer soils or rocks. For driven piles, the impact of the piling hammer induces compression and...Piles are long, slender structural elements used to transfer the loads from the superstructure through weak strata onto stiffer soils or rocks. For driven piles, the impact of the piling hammer induces compression and tension stresses in the piles. Hence, an important design consideration is to check that the strength of the pile is sufficient to resist the stresses caused by the impact of the pile hammer. Due to its complexity, pile drivability lacks a precise analytical solution with regard to the phenomena involved.In situations where measured data or numerical hypothetical results are available, neural networks stand out in mapping the nonlinear interactions and relationships between the system’s predictors and dependent responses. In addition, unlike most computational tools, no mathematical relationship assumption between the dependent and independent variables has to be made. Nevertheless, neural networks have been criticized for their long trial-and-error training process since the optimal configuration is not known a priori. This paper investigates the use of a fairly simple nonparametric regression algorithm known as multivariate adaptive regression splines（MARS）, as an alternative to neural networks, to approximate the relationship between the inputs and dependent response, and to mathematically interpret the relationship between the various parameters. In this paper, the Back propagation neural network（BPNN） and MARS models are developed for assessing pile drivability in relation to the prediction of the Maximum compressive stresses（MCS）, Maximum tensile stresses（MTS）, and Blow per foot（BPF）. A database of more than four thousand piles is utilized for model development and comparative performance between BPNN and MARS predictions.展开更多
This study aims to extend the multivariate adaptive regression splines(MARS)-Monte Carlo simulation(MCS) method for reliability analysis of slopes in spatially variable soils. This approach is used to explore the infl...This study aims to extend the multivariate adaptive regression splines(MARS)-Monte Carlo simulation(MCS) method for reliability analysis of slopes in spatially variable soils. This approach is used to explore the influences of the multiscale spatial variability of soil properties on the probability of failure(P_f) of the slopes. In the proposed approach, the relationship between the factor of safety and the soil strength parameters characterized with spatial variability is approximated by the MARS, with the aid of Karhunen-Loeve expansion. MCS is subsequently performed on the established MARS model to evaluate Pf.Finally, a nominally homogeneous cohesive-frictional slope and a heterogeneous cohesive slope, which are both characterized with different spatial variabilities, are utilized to illustrate the proposed approach.Results showed that the proposed approach can estimate the P_f of the slopes efficiently in spatially variable soils with sufficient accuracy. Moreover, the approach is relatively robust to the influence of different statistics of soil properties, thereby making it an effective and practical tool for addressing slope reliability problems concerning time-consuming deterministic stability models with low levels of P_f.Furthermore, disregarding the multiscale spatial variability of soil properties can overestimate or underestimate the P_f. Although the difference is small in general, the multiscale spatial variability of the soil properties must still be considered in the reliability analysis of heterogeneous slopes, especially for those highly related to cost effective and accurate designs.展开更多
The assessment of in situ permeability of rock mass is challenging for large-scale projects such as reservoirs created by dams,where water tightness issues are of prime importance.The in situ permeability is strongly ...The assessment of in situ permeability of rock mass is challenging for large-scale projects such as reservoirs created by dams,where water tightness issues are of prime importance.The in situ permeability is strongly related to the frequency and distribution of discontinuities in the rock mass and quantified by rock quality designation(RQD).This paper analyzes the data of hydraulic conductivity and discontinuities sampled at different depths during the borehole investigations in the limestone and sandstone formations for the construction of hydraulic structures in Oman.Cores recovered from boreholes provide RQD data,and in situ Lugeon tests elucidate the permeability.A modern technique of multivariate adaptive regression splines(MARS)assisted in correlating permeability and RQD along with the depth.In situ permeability shows a declining trend with increasing RQD,and the depth of investigation is within 50 m.This type of relationship can be developed based on detailed initial investigations at the site where the hydraulic conductivity of discontinuous rocks is required to be delineated.The relationship can approximate the permeability by only measuring the RQD in later investigations on the same site,thus saving the time and cost of the site investigations.The applicability of the relationship developed in this study to another location requires a lithological similarity of the rock mass that can be verified through preliminary investigation at the site.展开更多
In this study, a multivariate local quadratic polynomial regression(MLQPR) method is proposed to design a model for the sludge volume index(SVI). In MLQPR, a quadratic polynomial regression function is established to ...In this study, a multivariate local quadratic polynomial regression(MLQPR) method is proposed to design a model for the sludge volume index(SVI). In MLQPR, a quadratic polynomial regression function is established to describe the relationship between SVI and the relative variables, and the important terms of the quadratic polynomial regression function are determined by the significant test of the corresponding coefficients. Moreover, a local estimation method is introduced to adjust the weights of the quadratic polynomial regression function to improve the model accuracy. Finally, the proposed method is applied to predict the SVI values in a real wastewater treatment process(WWTP). The experimental results demonstrate that the proposed MLQPR method has faster testing speed and more accurate results than some existing methods.展开更多
In high mountainous areas, the development and distribution of alpine permafrost is greatly affected by macro- and mi- cro-topographic factors. The effects of latitude, altitude, slope, and aspect on the distribution ...In high mountainous areas, the development and distribution of alpine permafrost is greatly affected by macro- and mi- cro-topographic factors. The effects of latitude, altitude, slope, and aspect on the distribution of permafrost were studied to under- stand the dislribution patterns of permafrost in Wenquan on the Qinghai-Tibet Plateau. Cluster and correlation analysis were per- formed based on 30 m Global Digital Elevation Model （GDEM） data and field data obtained using geophysical exploration and borehole drilling methods. A Multivariate Adaptive Regression Spline model （MARS） was developed to simulate permafrost spa- tial distribution over the studied area. A validation was followed by comparing to 201 geophysical exploration sites, as well as by comparing to two other models, i.e., a binary logistic regression model and the Mean Annual Ground Temperature model （IVlAGT）. The MARS model provides a better simulation than the other two models. Besides the control effect of elevation on permafrost distribution, the MARS model also takes into account the impact of direct solar radiation on permafrost distribution.展开更多
This paper makes an approach to the approximate optimum in structural design,which combines the global response surface（GRS） based multivariate adaptive regression splines（MARS） with Move-Limit strategy（MLS）.MAR...This paper makes an approach to the approximate optimum in structural design,which combines the global response surface（GRS） based multivariate adaptive regression splines（MARS） with Move-Limit strategy（MLS）.MARS is an adaptive regression process,which fits in with the multidimensional problems.It adopts a modified recursive partitioning strategy to simplify high-dimensional problems into smaller highly accurate models.MLS for moving and resizing the search sub-regions is employed in the space of design variables.The quality of the approximation functions and the convergence history of the optimization process are reflected in MLS.The disadvantages of the conventional response surface method（RSM） have been avoided,specifically,highly nonlinear high-dimensional problems.The GRS/MARS with MLS is applied to a high-dimensional test function and an engineering problem to demonstrate its feasibility and convergence,and compared with quadratic response surface（QRS） models in terms of computational efficiency and accuracy.展开更多
Multivariate seemingly unrelated regression system is raised first and the two stage estimation and its covariance matrix are given. The results of the literatures[1-5] are extended in this paper.
Japanese Spanish mackerel,Scomberomorus niphonius,is a commercially important,highly migratory species that is widely distributed throughout the northwestern Pacific region.However,its life history and migratory patte...Japanese Spanish mackerel,Scomberomorus niphonius,is a commercially important,highly migratory species that is widely distributed throughout the northwestern Pacific region.However,its life history and migratory patterns are only partially understood.This study used otolith chemistry to investigate the migratory pattern of S.niphonius in the southern Yellow Sea,an important fishing ground.Transverse sections of otoliths from 15 age-1 spawning or spent individuals,comprising up to one complete migration cycle,were analyzed from the core to the margin by using laser ablation inductively coupled plasma mass spectrometry.The ratios of the element to Ca were integrated with microstructural analysis to produce age-related elemental profiles.Combining multielemental analysis of otolith composition with multivariate analytical models,we quantified structural changes in otolith chemistry profiles.Results revealed there were diverse changing patterns of otolith chemistry profiles for detected elements and the elements of Na,Mg,Sr and Ba were important for the chronological signal.Five clusters were identified through chronological clustering,representing the five life stages from the early stage to the spawning stage.Variation of Ba:Ca ratio was most informative,showing a step-decreasing pattern in the first four stages and a rebound in the spawning stage.These results support the hypothesized migratory pattern of S.niphonius:hatching and spending their early life in the coastal sandy ridges system of the southern Yellow Sea,migrating northeastward and offshore for feeding during juvenile stage,aggregating in early October and migrating outward to the Jeju Island for wintering,and returning to the coastal waters for spawning.This study demonstrated the value of life-history related otolith chemistry profiles combined with multivariate analytical models was a means to verify the migration patterns of S.niphonius at regional scales with potential application in fisheries assessment and management.展开更多
Boosting algorithms are a class of general methods used to improve the general periormance of regression analysis. The main idea is to maintain a distribution over the train set. In order to use the given distribution...Boosting algorithms are a class of general methods used to improve the general periormance of regression analysis. The main idea is to maintain a distribution over the train set. In order to use the given distribution directly, a modified PLS algorithm is proposed and used as the base learner to deal with the nonlinear multivariate regression problems. Experiments on gasoline octane number prediction demonstrate that boosting the modified PLS algorithm has better general performance over the PLS algorithm.展开更多
A multivariable regression(MVR) approach is proposed to identify the real power transfer between generators and loads.Based on solved load flow results,it first uses modified nodal equation method(MNE) to determine re...A multivariable regression(MVR) approach is proposed to identify the real power transfer between generators and loads.Based on solved load flow results,it first uses modified nodal equation method(MNE) to determine real power contribution from each generator to loads.Then,the results of MNE method and load flow information are utilized to determine suitable regression coefficients using MVR model to estimate the power transfer.The 25-bus equivalent system of south Malaysia is utilized as a test system to illustrate the effectiveness of the MVR output compared to that of the MNE method.The error of the estimate of MVR method ranges from 0.001 4 to 0.007 9.Furthermore,when compared to MNE method,MVR method computes generator contribution to loads within 26.40 ms whereas the MNE method takes 360 ms for the calculation of same real power transfer allocation.Therefore,MVR method is more suitable for real time power transfer allocation.展开更多
NonorthogonalMultiple Access(NOMA)is incorporated into the wireless network systems to achieve better connectivity,spectral and energy effectiveness,higher data transfer rate,and also obtain the high quality of servic...NonorthogonalMultiple Access(NOMA)is incorporated into the wireless network systems to achieve better connectivity,spectral and energy effectiveness,higher data transfer rate,and also obtain the high quality of services(QoS).In order to improve throughput and minimum latency,aMultivariate Renkonen Regressive Weighted Preference Bootstrap Aggregation based Nonorthogonal Multiple Access(MRRWPBA-NOMA)technique is introduced for network communication.In the downlink transmission,each mobile device’s resources and their characteristics like energy,bandwidth,and trust are measured.Followed by,the Weighted Preference Bootstrap Aggregation is applied to recognize the resource-efficient mobile devices for aware data transmission by constructing the different weak hypotheses i.e.,Multivariate Renkonen Regression functions.Based on the classification,resource and trust-aware devices are selected for transmission.Simulation of the proposed MRRWPBA-NOMA technique and existing methods are carried out with different metrics such as data delivery ratio,throughput,latency,packet loss rate,and energy efficiency,signaling overhead.The simulation results assessment indicates that the proposed MRRWPBA-NOMA outperforms well than the conventional methods.展开更多
Small-scale measurements of the radon exhalation rate using the flow-through and closed-loop methods were conducted on the surface of a uranium tailing pond to better understand the differences between the two methods...Small-scale measurements of the radon exhalation rate using the flow-through and closed-loop methods were conducted on the surface of a uranium tailing pond to better understand the differences between the two methods.An abnormal radon exhalation behavior was observed,leading to computational fluid dynamics(CFD)-based simulations in which dynamic radon migration in a porous medium and accumulation chamber was considered.Based on the in-situ experimental and numerical simulation results,variations in the radon exhalation rate subject to permeability,flow rate,and insertion depth were quantified and analyzed.The in-situ radon exhalation rates measured using the flow-through method were higher than those measured using the closed-loop method,which could be explained by the negative pressure difference between the inside and outside of the chamber during the measurements.The consistency of the variations in the radon exhalation rate between the experiments and simulations suggests the reliability of CFD-based techniques in obtaining the dynamic evolution of transient radon exhalation rates for diffusion and convection at the porous medium-air interface.The synergistic effects of the three factors(insertion depth,flow rate,and permeability)on the negative pressure difference and measured exhalation rate were quantified,and multivariate regression models were established,with positive correlations in most cases;the exhalation rate decreased with increasing insertion depth at a permeability of 1×10^(−11) m^(2).CFD-based simulations can provide theoretical guidance for improving the flow-through method and thus achieve accurate measurements.展开更多
Tunnel heading stability in two dimensions(2D)has been extensively investigated by numerous scholars in the past decade.One significant limitation of 2D analysis is the absence of actual tunnel geometry modeling with ...Tunnel heading stability in two dimensions(2D)has been extensively investigated by numerous scholars in the past decade.One significant limitation of 2D analysis is the absence of actual tunnel geometry modeling with a considerable degree of idealization.Nevertheless,it is possible to study the stability of tunnels in three dimensions(3D)with a rectangular shape using finite element limit analysis(FELA)and a nonlinear programming technique.This paper employs 3D FELA to generate rigorous solutions for stability numbers,failure mechanisms,and safety factors for rectangular-shaped tunnels.To further explore the usefulness of the produced results,multivariate adaptive regression spline(MARS)is used for machine learning of big dataset and development of design equations for practical design applications.The study should be of great benefit to tunnel design practices using the developed equations provided in the paper.展开更多
Machine learning methods have advantages in predicting excavation-induced lateral wall displacements.Due to lack of sufficient field data,training data for prediction models were often derived from the results of nume...Machine learning methods have advantages in predicting excavation-induced lateral wall displacements.Due to lack of sufficient field data,training data for prediction models were often derived from the results of numerical simulations,leading to poor prediction accuracy.Based on a specific quantity of data,a multivariate adaptive regression splines method(MARS)was introduced to predict lateral wall deflections caused by deep excavations in thick water-rich sands.Sensitivity of lateral wall deflections to affecting factors was analyzed.It is disclosed that dewatering mode has the most significant influence on lateral wall deflections,while the soil cohesion has the least influence.Using crossvalidation analysis,weights were introduced to modify the MARS method to optimize the prediction model.Comparison of the predicted and measured deflections shows that the prediction based on the modified multivariate adaptive regression splines method(MMARS)is more accurate than that based on the traditional MARS method.The prediction model established in this paper can help engineers make predictions for wall displacement,and the proposed methodology can also serve as a reference for researchers to develop prediction models.展开更多
An artificial neural network model was developed to predict the oxidation of refractory gold concentrate （RGC） by ozone and ferric ions. The concentration of ozone and ferric ions, pulp density, oxygen amount, leach...An artificial neural network model was developed to predict the oxidation of refractory gold concentrate （RGC） by ozone and ferric ions. The concentration of ozone and ferric ions, pulp density, oxygen amount, leaching time and temperature were employed as inputs to the network; the output of the network was the percentage of the ferric extraction iron from RGC. The multilayered feed-forward networks were trained by 33 sets of input-output patterns using a back propagation algorithm; a three-layer network with 8 neurons in the hidden layer gave optimal results. The model gave good predictions of high correlation coefficient （R2=0.966）. The predictions by ANN are more accurate when compared with conventional multivariate regression analysis （MVRA）. In addition, calculation with ANN model indicates that temperature is the predominant parameter and ozone concentration is the lesser influential parameter in the pre-oxidation process of refractory gold ore. The ANN neural network model accurately estimates the ferric extraction during pretreatment process of RGC in gold smelter plants and can be used to optimize the process parameters.展开更多
基金financially supported by National Key R&D Program of China(2021YFD220040403 and 2021YFD220040304)the China Scholarship Council(202107565021).
文摘Background: Vegetation distribution maps are of great significance for nature protection and management. In diverse tropical forests, accurate spatial mapping of vegetation types is challenging;the high species diversity and abundance of rare species challenge classification concepts, while remote sensing signals may not vary systematically with species composition, complicating the technical capability for delineating vegetation types in the landscape.Methods: We used a combination of field-based compositional data and their relations to environmental variables to predict the distribution of forest types in the Wuzhishan National Natural Reserve(WNNR), Hainan Island,China, using multivariate regression trees(MRT). The MRT was based on arboreal vegetation composition in 132plots of 20 m×20 m with a regular spacing of 1 km. Apart from the MRT, non-metric multidimensional scaling(NMDS) was used to evaluate vegetation-environment relationships.Results: The MRT model worked best when using 14 key environmental variables including topography, climate,latitude and soil, although the difference with the simpler model including only topographical variables was small. The full model classified the 132 plots into 3 vegetation types, 6 formation groups, 20 formations and 65associations at different hierarchical syntaxonomic levels. This model was the basis for forest vegetation maps for the WNNR. MRT and NMDS showed that elevation was the main driving force for the distribution of vegetation types and formation groups. Climate, latitude, and soil(especially available P), together with topographic variables, all influenced the distribution of formations and associations.Conclusions: While elevation determines forest-type distributions, lower-level syntaxonomic forest classes respond to the topographic diversity typical for mountains. Apart from providing the first detailed forest vegetation map for any part of WNNR, we show how, in spite of limitations, MRT with existing environmental data can be a useful method for mapping diverse and remote tropical forests.
基金the National Key Research and Development Program of China(2018YFC2000500)the Strategic Priority Research Program of the Chinese Academy of Sciences(XDB29020000)+1 种基金the National Natural Science Foundation of China(31771481 and 91857101)the Key Research Program of the Chinese Academy of Sciences(KFZD-SW-219),“China Microbiome Initiative.”。
文摘Recent technological advancements and developments have led to a dramatic increase in the amount of high-dimensional data and thus have increased the demand for proper and efficient multivariate regression methods.Numerous traditional multivariate approaches such as principal component analysis have been used broadly in various research areas,including investment analysis,image identification,and population genetic structure analysis.However,these common approaches have the limitations of ignoring the correlations between responses and a low variable selection efficiency.Therefore,in this article,we introduce the reduced rank regression method and its extensions,sparse reduced rank regression and subspace assisted regression with row sparsity,which hold potential to meet the above demands and thus improve the interpretability of regression models.We conducted a simulation study to evaluate their performance and compared them with several other variable selection methods.For different application scenarios,we also provide selection suggestions based on predictive ability and variable selection accuracy.Finally,to demonstrate the practical value of these methods in the field of microbiome research,we applied our chosen method to real population-level microbiome data,the results of which validated our method.Our method extensions provide valuable guidelines for future omics research,especially with respect to multivariate regression,and could pave the way for novel discoveries in microbiome and related research fields.
基金This work was supported by a grant fromthe Hubei Province Natural Science Foundation of China(No.2003 ABA151)
文摘Objective: To determine the independent prognostic factors in the recurrence of colonic carcinoma after curative resection. Methods: Two hundred and one patients undergoing curative resections for colonic carcinoma were investigated by univariate and Cox multivariate regression analyses. Ten factors contributed to the rate were analyzed. Results: Dukes stages, obstruction, postoperative chemotherapy as well as the growth manner of the tumor were significantly associated with the recurrence rate of colonic carcinoma (P<0.05) by univariate analysis, while Dukes stages, obstruction, and postoperative chemotherapy were significant factors by the multivariate analysis. Conclusion: Dukes stages, obstruction, and postoperative chemotherapy are independent prognostic factors in the recurrence of colonic carcinoma.
文摘Often many variables have to be analyzed for their importance in terms of significant contribution and predictability in medical research. One of the possible analytical tools may be the Multiple Linear Regression Analysis. However, research papers usually report both univariate and multivariate regression analyses of the data. The biostatistician sometimes faces practical difficulties while selecting the independent variables for logical inclusion in the multivariate analysis. The selection criteria for inclusion of a variable in the multivariate regression is that the variable at the univariate level should have a regression coefficient with p 〈 0.20. However, there is a chance that an independent variable with p 〉 0.20 at univariate regression may become significant in the multivariate regression analysis and vice versa, provided the above criteria is not strictly adhered to. We undertook both univariate and multivariate linear regression analyses on data from two multi-centric clinical trials. We recommend that there is no need to restrict the p value of 〈= 0.20. Because of high speed computer and availability of statistical software, the desired results could be achieved by considering all relevant independent variables in multivariate regression analysis.
文摘Abstract Using the method of stepwise multivariate linear regression (SMLR), the quantitative structure activity relationships (QSAR) of two isomeric series of taxol and its derivatives have been studied. It was found that the molar refractivity of the C3′substituent of the C13 side chain has significant correlation with its activity. We deduce that structural changes in the C3′substituents may be critical to the anticancer function. It would be useful to the design and synthesis of taxol like compounds with improved activities.
文摘Piles are long, slender structural elements used to transfer the loads from the superstructure through weak strata onto stiffer soils or rocks. For driven piles, the impact of the piling hammer induces compression and tension stresses in the piles. Hence, an important design consideration is to check that the strength of the pile is sufficient to resist the stresses caused by the impact of the pile hammer. Due to its complexity, pile drivability lacks a precise analytical solution with regard to the phenomena involved.In situations where measured data or numerical hypothetical results are available, neural networks stand out in mapping the nonlinear interactions and relationships between the system’s predictors and dependent responses. In addition, unlike most computational tools, no mathematical relationship assumption between the dependent and independent variables has to be made. Nevertheless, neural networks have been criticized for their long trial-and-error training process since the optimal configuration is not known a priori. This paper investigates the use of a fairly simple nonparametric regression algorithm known as multivariate adaptive regression splines（MARS）, as an alternative to neural networks, to approximate the relationship between the inputs and dependent response, and to mathematically interpret the relationship between the various parameters. In this paper, the Back propagation neural network（BPNN） and MARS models are developed for assessing pile drivability in relation to the prediction of the Maximum compressive stresses（MCS）, Maximum tensile stresses（MTS）, and Blow per foot（BPF）. A database of more than four thousand piles is utilized for model development and comparative performance between BPNN and MARS predictions.
基金supported by The Hong Kong Polytechnic University through the project RU3Ythe Research Grant Council through the project PolyU 5128/13E+1 种基金National Natural Science Foundation of China(Grant No.51778313)Cooperative Innovation Center of Engineering Construction and Safety in Shangdong Blue Economic Zone
文摘This study aims to extend the multivariate adaptive regression splines(MARS)-Monte Carlo simulation(MCS) method for reliability analysis of slopes in spatially variable soils. This approach is used to explore the influences of the multiscale spatial variability of soil properties on the probability of failure(P_f) of the slopes. In the proposed approach, the relationship between the factor of safety and the soil strength parameters characterized with spatial variability is approximated by the MARS, with the aid of Karhunen-Loeve expansion. MCS is subsequently performed on the established MARS model to evaluate Pf.Finally, a nominally homogeneous cohesive-frictional slope and a heterogeneous cohesive slope, which are both characterized with different spatial variabilities, are utilized to illustrate the proposed approach.Results showed that the proposed approach can estimate the P_f of the slopes efficiently in spatially variable soils with sufficient accuracy. Moreover, the approach is relatively robust to the influence of different statistics of soil properties, thereby making it an effective and practical tool for addressing slope reliability problems concerning time-consuming deterministic stability models with low levels of P_f.Furthermore, disregarding the multiscale spatial variability of soil properties can overestimate or underestimate the P_f. Although the difference is small in general, the multiscale spatial variability of the soil properties must still be considered in the reliability analysis of heterogeneous slopes, especially for those highly related to cost effective and accurate designs.
基金indebted to the Sohar University and the University of Buraimi, Oman, to support this study
文摘The assessment of in situ permeability of rock mass is challenging for large-scale projects such as reservoirs created by dams,where water tightness issues are of prime importance.The in situ permeability is strongly related to the frequency and distribution of discontinuities in the rock mass and quantified by rock quality designation(RQD).This paper analyzes the data of hydraulic conductivity and discontinuities sampled at different depths during the borehole investigations in the limestone and sandstone formations for the construction of hydraulic structures in Oman.Cores recovered from boreholes provide RQD data,and in situ Lugeon tests elucidate the permeability.A modern technique of multivariate adaptive regression splines(MARS)assisted in correlating permeability and RQD along with the depth.In situ permeability shows a declining trend with increasing RQD,and the depth of investigation is within 50 m.This type of relationship can be developed based on detailed initial investigations at the site where the hydraulic conductivity of discontinuous rocks is required to be delineated.The relationship can approximate the permeability by only measuring the RQD in later investigations on the same site,thus saving the time and cost of the site investigations.The applicability of the relationship developed in this study to another location requires a lithological similarity of the rock mass that can be verified through preliminary investigation at the site.
文摘In this study, a multivariate local quadratic polynomial regression(MLQPR) method is proposed to design a model for the sludge volume index(SVI). In MLQPR, a quadratic polynomial regression function is established to describe the relationship between SVI and the relative variables, and the important terms of the quadratic polynomial regression function are determined by the significant test of the corresponding coefficients. Moreover, a local estimation method is introduced to adjust the weights of the quadratic polynomial regression function to improve the model accuracy. Finally, the proposed method is applied to predict the SVI values in a real wastewater treatment process(WWTP). The experimental results demonstrate that the proposed MLQPR method has faster testing speed and more accurate results than some existing methods.
基金supported financially by the Special Basic Research Program of China(Grant No.2008FY110200)partially by Open Programme of State Key Laboratory(No.SKLFSE201009)
文摘In high mountainous areas, the development and distribution of alpine permafrost is greatly affected by macro- and mi- cro-topographic factors. The effects of latitude, altitude, slope, and aspect on the distribution of permafrost were studied to under- stand the dislribution patterns of permafrost in Wenquan on the Qinghai-Tibet Plateau. Cluster and correlation analysis were per- formed based on 30 m Global Digital Elevation Model （GDEM） data and field data obtained using geophysical exploration and borehole drilling methods. A Multivariate Adaptive Regression Spline model （MARS） was developed to simulate permafrost spa- tial distribution over the studied area. A validation was followed by comparing to 201 geophysical exploration sites, as well as by comparing to two other models, i.e., a binary logistic regression model and the Mean Annual Ground Temperature model （IVlAGT）. The MARS model provides a better simulation than the other two models. Besides the control effect of elevation on permafrost distribution, the MARS model also takes into account the impact of direct solar radiation on permafrost distribution.
基金Project supported by the National Natural Science Foundation of China (Grant No.50775084)the National Hightechnology Research and Development Program of China (Grant No.2006AA04Z121)
文摘This paper makes an approach to the approximate optimum in structural design,which combines the global response surface（GRS） based multivariate adaptive regression splines（MARS） with Move-Limit strategy（MLS）.MARS is an adaptive regression process,which fits in with the multidimensional problems.It adopts a modified recursive partitioning strategy to simplify high-dimensional problems into smaller highly accurate models.MLS for moving and resizing the search sub-regions is employed in the space of design variables.The quality of the approximation functions and the convergence history of the optimization process are reflected in MLS.The disadvantages of the conventional response surface method（RSM） have been avoided,specifically,highly nonlinear high-dimensional problems.The GRS/MARS with MLS is applied to a high-dimensional test function and an engineering problem to demonstrate its feasibility and convergence,and compared with quadratic response surface（QRS） models in terms of computational efficiency and accuracy.
基金Supported by the NSF of Henan Province(0611052600)
文摘Multivariate seemingly unrelated regression system is raised first and the two stage estimation and its covariance matrix are given. The results of the literatures[1-5] are extended in this paper.
基金The National Natural Science Foundation of China under contract Nos 41930534 and 41876177
文摘Japanese Spanish mackerel,Scomberomorus niphonius,is a commercially important,highly migratory species that is widely distributed throughout the northwestern Pacific region.However,its life history and migratory patterns are only partially understood.This study used otolith chemistry to investigate the migratory pattern of S.niphonius in the southern Yellow Sea,an important fishing ground.Transverse sections of otoliths from 15 age-1 spawning or spent individuals,comprising up to one complete migration cycle,were analyzed from the core to the margin by using laser ablation inductively coupled plasma mass spectrometry.The ratios of the element to Ca were integrated with microstructural analysis to produce age-related elemental profiles.Combining multielemental analysis of otolith composition with multivariate analytical models,we quantified structural changes in otolith chemistry profiles.Results revealed there were diverse changing patterns of otolith chemistry profiles for detected elements and the elements of Na,Mg,Sr and Ba were important for the chronological signal.Five clusters were identified through chronological clustering,representing the five life stages from the early stage to the spawning stage.Variation of Ba:Ca ratio was most informative,showing a step-decreasing pattern in the first four stages and a rebound in the spawning stage.These results support the hypothesized migratory pattern of S.niphonius:hatching and spending their early life in the coastal sandy ridges system of the southern Yellow Sea,migrating northeastward and offshore for feeding during juvenile stage,aggregating in early October and migrating outward to the Jeju Island for wintering,and returning to the coastal waters for spawning.This study demonstrated the value of life-history related otolith chemistry profiles combined with multivariate analytical models was a means to verify the migration patterns of S.niphonius at regional scales with potential application in fisheries assessment and management.
基金This work was supported by the National High-tech Research and Development Program of China (No. 2003AA412110).
文摘Boosting algorithms are a class of general methods used to improve the general periormance of regression analysis. The main idea is to maintain a distribution over the train set. In order to use the given distribution directly, a modified PLS algorithm is proposed and used as the base learner to deal with the nonlinear multivariate regression problems. Experiments on gasoline octane number prediction demonstrate that boosting the modified PLS algorithm has better general performance over the PLS algorithm.
文摘A multivariable regression(MVR) approach is proposed to identify the real power transfer between generators and loads.Based on solved load flow results,it first uses modified nodal equation method(MNE) to determine real power contribution from each generator to loads.Then,the results of MNE method and load flow information are utilized to determine suitable regression coefficients using MVR model to estimate the power transfer.The 25-bus equivalent system of south Malaysia is utilized as a test system to illustrate the effectiveness of the MVR output compared to that of the MNE method.The error of the estimate of MVR method ranges from 0.001 4 to 0.007 9.Furthermore,when compared to MNE method,MVR method computes generator contribution to loads within 26.40 ms whereas the MNE method takes 360 ms for the calculation of same real power transfer allocation.Therefore,MVR method is more suitable for real time power transfer allocation.
基金the Taif University Researchers Supporting Project number(TURSP-2020/36),Taif University,Taif,Saudi Arabiafundedby Princess Nourah bint Abdulrahman University Researchers Supporting Project Number(PNURSP2022R97), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia。
文摘NonorthogonalMultiple Access(NOMA)is incorporated into the wireless network systems to achieve better connectivity,spectral and energy effectiveness,higher data transfer rate,and also obtain the high quality of services(QoS).In order to improve throughput and minimum latency,aMultivariate Renkonen Regressive Weighted Preference Bootstrap Aggregation based Nonorthogonal Multiple Access(MRRWPBA-NOMA)technique is introduced for network communication.In the downlink transmission,each mobile device’s resources and their characteristics like energy,bandwidth,and trust are measured.Followed by,the Weighted Preference Bootstrap Aggregation is applied to recognize the resource-efficient mobile devices for aware data transmission by constructing the different weak hypotheses i.e.,Multivariate Renkonen Regression functions.Based on the classification,resource and trust-aware devices are selected for transmission.Simulation of the proposed MRRWPBA-NOMA technique and existing methods are carried out with different metrics such as data delivery ratio,throughput,latency,packet loss rate,and energy efficiency,signaling overhead.The simulation results assessment indicates that the proposed MRRWPBA-NOMA outperforms well than the conventional methods.
基金National Natural Science Foundation of China(No.11575080)Hunan Provincial Natural Science Foundation of China(No.2022JJ30482)Hunan Provincial Innovation Foundation for Postgraduate(No.QL20220206).
文摘Small-scale measurements of the radon exhalation rate using the flow-through and closed-loop methods were conducted on the surface of a uranium tailing pond to better understand the differences between the two methods.An abnormal radon exhalation behavior was observed,leading to computational fluid dynamics(CFD)-based simulations in which dynamic radon migration in a porous medium and accumulation chamber was considered.Based on the in-situ experimental and numerical simulation results,variations in the radon exhalation rate subject to permeability,flow rate,and insertion depth were quantified and analyzed.The in-situ radon exhalation rates measured using the flow-through method were higher than those measured using the closed-loop method,which could be explained by the negative pressure difference between the inside and outside of the chamber during the measurements.The consistency of the variations in the radon exhalation rate between the experiments and simulations suggests the reliability of CFD-based techniques in obtaining the dynamic evolution of transient radon exhalation rates for diffusion and convection at the porous medium-air interface.The synergistic effects of the three factors(insertion depth,flow rate,and permeability)on the negative pressure difference and measured exhalation rate were quantified,and multivariate regression models were established,with positive correlations in most cases;the exhalation rate decreased with increasing insertion depth at a permeability of 1×10^(−11) m^(2).CFD-based simulations can provide theoretical guidance for improving the flow-through method and thus achieve accurate measurements.
基金supported by the Thailand Science Research and Innovation Fundamental Fund fiscal year 2023The fifth author (V.Kamchoom)acknowledges the financial support from the National Science,Research and Innovation Fund (NSRF)at King Mongkut's Institute of Technology Ladkrabang (KMITL),Thailand (Grant No.FRB66065/0258-RE-KRIS/FF66/53)+1 种基金the Climate Change and Climate Variability Research in Monsoon Asia (CMON3)from the National Research Council of Thailand (NRCT) (Grant No.N10A650844)the National Natural Science Foundation of China (NSFC).
文摘Tunnel heading stability in two dimensions(2D)has been extensively investigated by numerous scholars in the past decade.One significant limitation of 2D analysis is the absence of actual tunnel geometry modeling with a considerable degree of idealization.Nevertheless,it is possible to study the stability of tunnels in three dimensions(3D)with a rectangular shape using finite element limit analysis(FELA)and a nonlinear programming technique.This paper employs 3D FELA to generate rigorous solutions for stability numbers,failure mechanisms,and safety factors for rectangular-shaped tunnels.To further explore the usefulness of the produced results,multivariate adaptive regression spline(MARS)is used for machine learning of big dataset and development of design equations for practical design applications.The study should be of great benefit to tunnel design practices using the developed equations provided in the paper.
基金Financial support from the National Natural Science Foundation of China(Grant No.42177179)is gratefully acknowledged.
文摘Machine learning methods have advantages in predicting excavation-induced lateral wall displacements.Due to lack of sufficient field data,training data for prediction models were often derived from the results of numerical simulations,leading to poor prediction accuracy.Based on a specific quantity of data,a multivariate adaptive regression splines method(MARS)was introduced to predict lateral wall deflections caused by deep excavations in thick water-rich sands.Sensitivity of lateral wall deflections to affecting factors was analyzed.It is disclosed that dewatering mode has the most significant influence on lateral wall deflections,while the soil cohesion has the least influence.Using crossvalidation analysis,weights were introduced to modify the MARS method to optimize the prediction model.Comparison of the predicted and measured deflections shows that the prediction based on the modified multivariate adaptive regression splines method(MMARS)is more accurate than that based on the traditional MARS method.The prediction model established in this paper can help engineers make predictions for wall displacement,and the proposed methodology can also serve as a reference for researchers to develop prediction models.
基金Project (2006AA06Z132) supported by High-tech Research and Development Program of ChinaProject (B604) supported by Leading Academic Discipline Project of Shanghai
文摘An artificial neural network model was developed to predict the oxidation of refractory gold concentrate （RGC） by ozone and ferric ions. The concentration of ozone and ferric ions, pulp density, oxygen amount, leaching time and temperature were employed as inputs to the network; the output of the network was the percentage of the ferric extraction iron from RGC. The multilayered feed-forward networks were trained by 33 sets of input-output patterns using a back propagation algorithm; a three-layer network with 8 neurons in the hidden layer gave optimal results. The model gave good predictions of high correlation coefficient （R2=0.966）. The predictions by ANN are more accurate when compared with conventional multivariate regression analysis （MVRA）. In addition, calculation with ANN model indicates that temperature is the predominant parameter and ozone concentration is the lesser influential parameter in the pre-oxidation process of refractory gold ore. The ANN neural network model accurately estimates the ferric extraction during pretreatment process of RGC in gold smelter plants and can be used to optimize the process parameters.
